#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P19957 uniprotkb:P00772 intact:EBI-8657434|ensembl:ENSP00000243924|uniprotkb:Q6FG74|intact:MINT-1519171|uniprotkb:E1P618 intact:EBI-986248|uniprotkb:Q29625|ensembl:ENSSSCP00070052099|ensembl:ENSSSCP00015042352|ensembl:ENSSSCP00045004195|ensembl:ENSSSCP00065026074 psi-mi:elaf_human(display_long)|uniprotkb:PI3(gene name)|psi-mi:PI3(display_short)|uniprotkb:WAP3(gene name synonym)|uniprotkb:WFDC14(gene name synonym)|uniprotkb:Elastase-specific inhibitor(gene name synonym)|uniprotkb:Skin-derived antileukoproteinase(gene name synonym)|uniprotkb:Peptidase inhibitor 3(gene name synonym)|uniprotkb:WAP four-disulfide core domain protein 14(gene name synonym)|uniprotkb:Protease inhibitor WAP3(gene name synonym) psi-mi:cela1_pig(display_long)|uniprotkb:CELA1(gene name)|psi-mi:CELA1(display_short)|uniprotkb:ELA1(gene name synonym)|uniprotkb:Elastase-1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Tsunemi et al. (1996) pubmed:8794736|mint:MINT-5221154 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8657461|mint:MINT-24855 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000124102(gene)|ensembl:ENST00000243924(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007620"(copulation)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0031012"(extracellular matrix)|go:"GO:0045087"(innate immune response)|interpro:IPR002098(Seminal vesicle protein I)|interpro:IPR008197(Whey acidic protein, 4-disulphide core)|interpro:IPR019541|interpro:IPR036645|rcsb pdb:1FLE|rcsb pdb:2REL|rcsb pdb:6ATU|reactome:R-HSA-6803157|reactome:R-HSA-6809371|refseq:NP_002629.1|mint:MINT-1519198(identity) refseq:XP_005655631.1|refseq:NP_998988.1|ensembl:ENSSSCT00015102157(transcript)|ensembl:ENSSSCT00045006201(transcript)|ensembl:ENSSSCT00065060127(transcript)|ensembl:ENSSSCT00070061127(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0046872"(metal ion binding)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|rcsb pdb:1B0E|rcsb pdb:1BMA|rcsb pdb:1BTU|rcsb pdb:1C1M|rcsb pdb:1E34|rcsb pdb:1E35|rcsb pdb:1E36|rcsb pdb:1E37|rcsb pdb:1E38|rcsb pdb:1EAI|rcsb pdb:1EAS|rcsb pdb:1EAT|rcsb pdb:1EAU|rcsb pdb:1ELA|rcsb pdb:1ELB|rcsb pdb:1ELC|ensembl:ENSSSCG00015075833(gene)|ensembl:ENSSSCG00045003737(gene)|ensembl:ENSSSCG00065043957(gene)|ensembl:ENSSSCG00070030376(gene)|rcsb pdb:1ELD|rcsb pdb:1ELE|rcsb pdb:1ELF|rcsb pdb:1ELG|rcsb pdb:1ESA|rcsb pdb:1ESB|rcsb pdb:1H9L|rcsb pdb:1HAX|rcsb pdb:1HAY|rcsb pdb:1HAZ|rcsb pdb:1HB0|rcsb pdb:1HV7|rcsb pdb:1INC|rcsb pdb:1JIM|rcsb pdb:1L0Z|rcsb pdb:1L1G|rcsb pdb:1EST|rcsb pdb:1FLE|rcsb pdb:1LKA|rcsb pdb:1LKB|rcsb pdb:1LVY|rcsb pdb:1FZZ|rcsb pdb:1MCV|rcsb pdb:1MMJ|rcsb pdb:1GVK|rcsb pdb:1GWA|rcsb pdb:1NES|rcsb pdb:1OKX|rcsb pdb:1QGF|rcsb pdb:1QIX|rcsb pdb:1QNJ|rcsb pdb:1QR3|rcsb pdb:1UO6|rcsb pdb:1UVO|rcsb pdb:1UVP|rcsb pdb:2A7C|rcsb pdb:2A7J|rcsb pdb:2BB4|rcsb pdb:2BD2|rcsb pdb:2BD3|rcsb pdb:2BD5|rcsb pdb:2BD7|rcsb pdb:2BD8|rcsb pdb:2BD9|rcsb pdb:2BDA|rcsb pdb:2BDB|rcsb pdb:2BDC|rcsb pdb:2BLO|rcsb pdb:2BLQ|rcsb pdb:2CV3|rcsb pdb:2D26|rcsb pdb:2DE8|rcsb pdb:2DE9|rcsb pdb:2EST|rcsb pdb:2FO9|rcsb pdb:2FOA|rcsb pdb:2FOB|rcsb pdb:2FOC|rcsb pdb:2FOD|rcsb pdb:2FOE|rcsb pdb:2FOF|rcsb pdb:2FOG|rcsb pdb:2FOH|rcsb pdb:2G4T|rcsb pdb:2G4U|rcsb pdb:2H1U|rcsb pdb:2IOT|rcsb pdb:2OQU|rcsb pdb:2V0B|rcsb pdb:2V35|rcsb pdb:3E3T|rcsb pdb:3EST|rcsb pdb:3HGN|rcsb pdb:3HGP|rcsb pdb:3MNB|rcsb pdb:3MNC|rcsb pdb:3MNS|rcsb pdb:3MNX|rcsb pdb:3MO3|rcsb pdb:3MO6|rcsb pdb:3MO9|rcsb pdb:3MOC|rcsb pdb:3MTY|rcsb pdb:3MU0|rcsb pdb:3MU1|rcsb pdb:3MU4|rcsb pdb:3MU5|rcsb pdb:3MU8|rcsb pdb:2BD4|rcsb pdb:3ODD|rcsb pdb:3ODF|rcsb pdb:3UOU|rcsb pdb:4EST|rcsb pdb:4GVU|rcsb pdb:4YM9|rcsb pdb:5AVD|rcsb pdb:5EST|rcsb pdb:6EST|rcsb pdb:6Q8S|rcsb pdb:6QBU|rcsb pdb:6QEN|rcsb pdb:6QEO|rcsb pdb:6TH7|rcsb pdb:7EST|rcsb pdb:9EST|rcsb pdb:8EST|dip:DIP-378N|mint:MINT-1519191(identity) - comment:mint|function:Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:In the xray complex 1fle, P00772 is chain E and P19957 is chain I Resolution 1.900|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/02/12 2014/10/16 rogid:PyCOpNgmCcwUckWUfatAq4ptJog9606 rogid:arE2fjBcj7ZqyshQz9Uajas279k9823 intact-crc:D2EC35C172CA84B1|rigid:GCwzWp35YEOLHTgl1fNi0/OlEYo false tag:?-?(MINT-1519199) tag:?-?(MINT-1519192) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)