#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q99M75 uniprotkb:P07174 intact:EBI-7370412|intact:MINT-243866|ensembl:ENSRNOP00000041517 intact:EBI-1038810 psi-mi:rtn4r_rat(display_long)|uniprotkb:Rtn4r(gene name)|psi-mi:Rtn4r(display_short)|uniprotkb:Nogor(gene name synonym)|uniprotkb:Nogo receptor(gene name synonym)|uniprotkb:Nogo-66 receptor(gene name synonym) psi-mi:tnr16_rat(display_long)|uniprotkb:Ngfr(gene name)|psi-mi:Ngfr(display_short)|uniprotkb:Tnfrsf16(gene name synonym)|uniprotkb:Low-affinity nerve growth factor receptor(gene name synonym)|uniprotkb:Gp80-LNGFR(gene name synonym)|uniprotkb:p75 ICD(gene name synonym)|uniprotkb:Low affinity neurotrophin receptor p75NTR(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yu et al. (2004) pubmed:15527766|imex:IM-13935|mint:MINT-5217280 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7370404|mint:MINT-50780|imex:IM-13935-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620810|refseq:NP_446065.1|interpro:IPR032675|rcsb pdb:3KJ4|ensembl:ENSRNOG00000030920(gene)|ensembl:ENSRNOT00000051037(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0030426"(growth cone)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038131"(neuregulin receptor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905573"(ganglioside GM1 binding)|go:"GO:1905576"(ganglioside GT1b binding)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|mint:MINT-1208460(identity) rgd:3177|refseq:NP_036742.2|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0005035"(death receptor activity)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010941"(regulation of cell death)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0007165"(signal transduction)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016048"(detection of temperature stimulus)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021675"(nerve development)|go:"GO:0030135"(coated vesicle)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032224"(positive regulation of synaptic transmission, cholinergic)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0009611"(response to wounding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0009986"(cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035907"(dorsal aorta development)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042488"(positive regulation of odontogenesis of dentin-containing tooth)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043121"(neurotrophin binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048406"(nerve growth factor binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051799"(negative regulation of hair follicle development)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0070678"(preprotein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR022325|interpro:IPR034046|interpro:IPR041448|rcsb pdb:1NGR|rcsb pdb:1SG1|rcsb pdb:2MIC|rcsb pdb:2MJO|rcsb pdb:3BUK|rcsb pdb:3IJ2|rcsb pdb:4F42|rcsb pdb:4F44|reactome:R-RNO-193634|reactome:R-RNO-193692|reactome:R-RNO-205017|reactome:R-RNO-205025|reactome:R-RNO-205043|reactome:R-RNO-209543|reactome:R-RNO-209560|reactome:R-RNO-209563|go:"GO:0051897"(positive regulation of protein kinase B signaling)|mint:P07174|dip:DIP-5715N|mint:MINT-1208456(identity) - function:Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system|comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2C|comment:The interaction is detecable only in the Triton-insoluble fraction|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2004/12/14 2014/10/16 rogid:JNKz36jyj56yCZdDB3464B0mhgY10116 rogid:lscumOKfwxDCsoAs1EZfp6iFwz410116 intact-crc:2BDFF9BC7CDD18A8|rigid:SNIwCzVvxbr5qPN71rIlGh442gs false tag:?-?(MINT-1208461) - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot)