#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P14555	uniprotkb:P18054	intact:EBI-726473|uniprotkb:Q6DN24|uniprotkb:Q6IBD9|uniprotkb:Q9UCD2|uniprotkb:A8K5I7|ensembl:ENSP00000364252|ensembl:ENSP00000383364|ensembl:ENSP00000504762	intact:EBI-1633210|uniprotkb:O95569|uniprotkb:Q6ISF8|uniprotkb:Q9UQM4|ensembl:ENSP00000251535	psi-mi:pa2ga_human(display_long)|uniprotkb:Phosphatidylcholine 2-acylhydrolase 2A(gene name synonym)|uniprotkb:Group IIA phospholipase A2(gene name synonym)|uniprotkb:GIIC sPLA2(gene name synonym)|uniprotkb:Non-pancreatic secretory phospholipase A2(gene name synonym)|uniprotkb:PLA2G2A(gene name)|psi-mi:PLA2G2A(display_short)|uniprotkb:PLA2B(gene name synonym)|uniprotkb:PLA2L(gene name synonym)|uniprotkb:RASF-A(gene name synonym)	psi-mi:lox12_human(display_long)|uniprotkb:"Arachidonate (12S)-lipoxygenase"(gene name synonym)|uniprotkb:"Arachidonate (15S)-lipoxygenase"(gene name synonym)|uniprotkb:"Linoleate (13S)-lipoxygenase"(gene name synonym)|uniprotkb:ALOX12(gene name)|psi-mi:ALOX12(display_short)|uniprotkb:LOG12(gene name synonym)|uniprotkb:Platelet-type lipoxygenase 12(gene name synonym)|uniprotkb:12LO(gene name synonym)|uniprotkb:Lipoxin synthase 12-LO(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Coffey et al. (2004)	pubmed:15474031|imex:IM-13918|mint:MINT-5217235	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7348140|mint:MINT-50574|imex:IM-13918-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000291.1|refseq:NP_001155199.1|refseq:NP_001155200.1|refseq:NP_001155201.1|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0102567"|go:"GO:0102568"|go:"GO:1902563"(regulation of neutrophil activation)|interpro:IPR001211(Phospholipase A2, eukaryotic)|interpro:IPR016090(Phospholipase A2)|interpro:IPR033112|interpro:IPR033113|interpro:IPR036444|rcsb pdb:1AYP|rcsb pdb:1BBC|rcsb pdb:1DB4|rcsb pdb:1DB5|rcsb pdb:1DCY|rcsb pdb:1J1A|rcsb pdb:1KQU|rcsb pdb:1KVO|rcsb pdb:1N28|rcsb pdb:1N29|rcsb pdb:1POD|go:"GO:0050482"(arachidonic acid secretion)|rcsb pdb:2GNY|rcsb pdb:3U8B|rcsb pdb:3U8D|rcsb pdb:3U8H|rcsb pdb:3U8I|rcsb pdb:5G3N|reactome:R-HSA-1482788|reactome:R-HSA-1482801|reactome:R-HSA-1482839|reactome:R-HSA-1482922|reactome:R-HSA-1482925|reactome:R-HSA-1483166|reactome:R-HSA-6803157|rcsb pdb:1POE|ensembl:ENSG00000188257(gene)|ensembl:ENST00000375111(transcript)|ensembl:ENST00000400520(transcript)|ensembl:ENST00000482011(transcript)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019835"(cytolysis)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0046337"(phosphatidylethanolamine metabolic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046473"(phosphatidic acid metabolic process)|go:"GO:0047498"(calcium-dependent phospholipase A2 activity)|mint:MINT-1206469(identity)	refseq:NP_000688.2|ensembl:ENSG00000108839(gene)|ensembl:ENST00000251535(transcript)|go:"GO:0004052"("arachidonate 12(S)-lipoxygenase activity")|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007568"(aging)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016165"(linoleate 13S-lipoxygenase activity)|go:"GO:0016702"(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0033559"(unsaturated fatty acid metabolic process)|go:"GO:0034440"(lipid oxidation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0047977"(hepoxilin-epoxide hydrolase activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050473"(arachidonate 15-lipoxygenase activity)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:1901751"(leukotriene A4 metabolic process)|go:"GO:1905956"(positive regulation of endothelial tube morphogenesis)|go:"GO:2001303"(lipoxin A4 biosynthetic process)|go:"GO:2001306"(lipoxin B4 biosynthetic process)|interpro:IPR000907(Lipoxygenase)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR001885(Lipoxygenase, mammalian)|interpro:IPR013819(Lipoxygenase, C-terminal)|interpro:IPR020833|interpro:IPR020834|interpro:IPR036226|interpro:IPR036392|interpro:IPR042062|rcsb pdb:2ABU|rcsb pdb:3D3L|reactome:R-HSA-2142696|reactome:R-HSA-2142700|reactome:R-HSA-2142712|reactome:R-HSA-9018677|reactome:R-HSA-9025106|reactome:R-HSA-9026290|mint:MINT-1206465(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2|comment:BIOSOURCE=platelets of human tyrodes|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-platelet)|taxid:9606(Homo sapiens platelet, thrombocytes)	-	2004/11/29	2014/10/16	rogid:DgzoDPJ3UPjvBQ/3Ls/4N7QSQBY9606	rogid:8rflal3gFNTu9CHevTRRmen+r2Y9606	intact-crc:6054102D287864E2|rigid:t8a3Ss3/X+x9Anv+6td3PdFprKE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)