#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8R4E9 uniprotkb:O88513 intact:EBI-457043|uniprotkb:Q8BUQ1|uniprotkb:Q8BX29|uniprotkb:Q8R3V0|uniprotkb:Q8R4E8|ensembl:ENSMUSP00000006760 intact:EBI-445922|ensembl:ENSMUSP00000006898|ensembl:ENSMUSP00000106011 psi-mi:cdt1_mouse(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:Retroviral insertion site 2 protein(gene name synonym)|uniprotkb:Cdt1(gene name)|psi-mi:Cdt1(display_short)|uniprotkb:Ris2(gene name synonym) psi-mi:gemi_mouse(display_long)|uniprotkb:Gmnn(gene name)|psi-mi:Gmnn(display_short) psi-mi:"MI:0114"(x-ray crystallography) Lee et al. (2004) pubmed:15286659 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-457211|rcsb pdb:1WLQ - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_080290.3|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|ensembl:ENSMUSG00000006585(gene)|ensembl:ENSMUST00000006760(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|rcsb pdb:2KLO|rcsb pdb:2RQQ|rcsb pdb:2ZXX|rcsb pdb:3A4C|reactome:R-MMU-68827|reactome:R-MMU-68867|reactome:R-MMU-68949|reactome:R-MMU-68962|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like) refseq:NP_065592.1|refseq:XP_006516786.1|dip:DIP-32562N|ensembl:ENSMUSG00000006715(gene)|ensembl:ENSMUST00000006898(transcript)|ensembl:ENSMUST00000110382(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000104"(negative regulation of DNA-dependent DNA replication)|interpro:IPR022786|interpro:IPR029697|reactome:R-MMU-68827|reactome:R-MMU-68962|rcsb pdb:2ZXX - - - complex-properties:|3d-resolution:2.80|3d-r-factors:working 23.1%, free 28.5% taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/11/09 2014/10/16 rogid:GkxXG8geC2JHCrw2tNWQzIhf+W410090 rogid:FnezPIg7tsn2yJ4U6vb01AIZOfs10090 intact-crc:143AC07B6A95C643|rigid:V3lEerxyL+sE2bvbiQhQ0XbFtYg false binding-associated region:159-355 binding-associated region:79-157 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)