#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9QZR5 uniprotkb:P06876 intact:EBI-366905|uniprotkb:O88905|uniprotkb:Q99P45|uniprotkb:Q99P46|uniprotkb:Q9D2E6|uniprotkb:Q9D474|uniprotkb:Q9EQL2|uniprotkb:Q9QZR4|ensembl:ENSMUSP00000124133 intact:EBI-366934|uniprotkb:Q61929|uniprotkb:E9QMG8|ensembl:ENSMUSP00000020158 psi-mi:hipk2_mouse(display_long)|uniprotkb:Hipk2(gene name)|psi-mi:Hipk2(display_short)|uniprotkb:Nbak1(gene name synonym)|uniprotkb:Stank(gene name synonym)|uniprotkb:Nuclear body-associated kinase 1(gene name synonym)|uniprotkb:Sialophorin tail-associated nuclear serine/threonine-protein kinase(gene name synonym) psi-mi:myb_mouse(display_long)|uniprotkb:Myb(gene name)|psi-mi:Myb(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kanei-Ishii et al. (2004) pubmed:15082531 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-366889 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129537.1|refseq:NP_034563.2|ensembl:ENSMUSG00000061436|ensembl:ENSMUSG00000061436(gene)|ensembl:ENSMUST00000161779(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010842"(retina layer formation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046332"(SMAD binding)|go:"GO:0046790"(virion binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9QZR5|reactome:R-MMU-3899300|reactome:R-MMU-6804756|reactome:R-MMU-8939243|reactome:R-MMU-9022692|refseq:NP_001281072.1|refseq:NP_001281073.1|dip:DIP-31712N refseq:NP_001185843.1|refseq:NP_034978.3|rcsb pdb:1MBE|rcsb pdb:1MBF|rcsb pdb:1MBG|rcsb pdb:1MBH|rcsb pdb:1MBJ|rcsb pdb:1MBK|rcsb pdb:1MSE|rcsb pdb:1MSF|rcsb pdb:1SB0|rcsb pdb:2AGH|rcsb pdb:6DMX|rcsb pdb:6DNQ|rcsb pdb:1IDZ|ensembl:ENSMUSG00000019982(gene)|ensembl:ENSMUST00000020158(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017145"(stem cell division)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|rcsb pdb:1GUU|rcsb pdb:1GV2|rcsb pdb:1GV5|rcsb pdb:1GVD|rcsb pdb:1H88|rcsb pdb:1H89|rcsb pdb:1IDY|dip:DIP-31713N - crc64:5C863BE377F3AAEF - comment:MYB was deletion mutant lacking transcriptional activator domain|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/06/10 2014/10/16 rogid:QuwURfphVnnlJdiKOk6l4fDgtQM10090 rogid:BHCfLLes3QMOQXPc0SgbXNPldhw10090 intact-crc:B39BB0DB1AD2E06E|rigid:qKN/04zu5dIvhriJDNdxgQc5RS0 false sufficient binding region:757-896 sufficient binding region:?-?,1-274 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O54949 uniprotkb:Q9QZR5 intact:EBI-366894|uniprotkb:Q6PF98|uniprotkb:Q5SYE6|ensembl:ENSMUSP00000119345 intact:EBI-366905|uniprotkb:O88905|uniprotkb:Q99P45|uniprotkb:Q99P46|uniprotkb:Q9D2E6|uniprotkb:Q9D474|uniprotkb:Q9EQL2|uniprotkb:Q9QZR4|ensembl:ENSMUSP00000124133 psi-mi:nlk_mouse(display_long)|uniprotkb:Nlk(gene name)|psi-mi:Nlk(display_short)|uniprotkb:Nemo-like kinase(gene name synonym) psi-mi:hipk2_mouse(display_long)|uniprotkb:Hipk2(gene name)|psi-mi:Hipk2(display_short)|uniprotkb:Nbak1(gene name synonym)|uniprotkb:Stank(gene name synonym)|uniprotkb:Nuclear body-associated kinase 1(gene name synonym)|uniprotkb:Sialophorin tail-associated nuclear serine/threonine-protein kinase(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kanei-Ishii et al. (2004) pubmed:15082531 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-366928 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032728.3|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042501"(serine phosphorylation of STAT protein)|ensembl:ENSMUSG00000017376(gene)|ensembl:ENSMUST00000142739(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-MMU-4086398 refseq:NP_001129537.1|refseq:NP_034563.2|ensembl:ENSMUSG00000061436|ensembl:ENSMUSG00000061436(gene)|ensembl:ENSMUST00000161779(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010842"(retina layer formation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046332"(SMAD binding)|go:"GO:0046790"(virion binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9QZR5|reactome:R-MMU-3899300|reactome:R-MMU-6804756|reactome:R-MMU-8939243|reactome:R-MMU-9022692|refseq:NP_001281072.1|refseq:NP_001281073.1|dip:DIP-31712N - - crc64:5C863BE377F3AAEF dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/06/10 2014/10/16 rogid:hoiMW9ZcjnQXDyaFlxEHS9064a010090 rogid:QuwURfphVnnlJdiKOk6l4fDgtQM10090 intact-crc:387CC36E5FEDABA5|rigid:ybSR1otJ6/A4MvaHC4yiZKS8qFU false sufficient binding region:124-527 sufficient binding region:655-920 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06876 uniprotkb:Q9QZR5 intact:EBI-366934|uniprotkb:Q61929|uniprotkb:E9QMG8|ensembl:ENSMUSP00000020158 intact:EBI-366905|uniprotkb:O88905|uniprotkb:Q99P45|uniprotkb:Q99P46|uniprotkb:Q9D2E6|uniprotkb:Q9D474|uniprotkb:Q9EQL2|uniprotkb:Q9QZR4|ensembl:ENSMUSP00000124133 psi-mi:myb_mouse(display_long)|uniprotkb:Myb(gene name)|psi-mi:Myb(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:hipk2_mouse(display_long)|uniprotkb:Hipk2(gene name)|psi-mi:Hipk2(display_short)|uniprotkb:Nbak1(gene name synonym)|uniprotkb:Stank(gene name synonym)|uniprotkb:Nuclear body-associated kinase 1(gene name synonym)|uniprotkb:Sialophorin tail-associated nuclear serine/threonine-protein kinase(gene name synonym) psi-mi:"MI:0096"(pull down) Kanei-Ishii et al. (2004) pubmed:15082531 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-366949 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185843.1|refseq:NP_034978.3|rcsb pdb:1MBE|rcsb pdb:1MBF|rcsb pdb:1MBG|rcsb pdb:1MBH|rcsb pdb:1MBJ|rcsb pdb:1MBK|rcsb pdb:1MSE|rcsb pdb:1MSF|rcsb pdb:1SB0|rcsb pdb:2AGH|rcsb pdb:6DMX|rcsb pdb:6DNQ|rcsb pdb:1IDZ|ensembl:ENSMUSG00000019982(gene)|ensembl:ENSMUST00000020158(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017145"(stem cell division)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|rcsb pdb:1GUU|rcsb pdb:1GV2|rcsb pdb:1GV5|rcsb pdb:1GVD|rcsb pdb:1H88|rcsb pdb:1H89|rcsb pdb:1IDY|dip:DIP-31713N refseq:NP_001129537.1|refseq:NP_034563.2|ensembl:ENSMUSG00000061436|ensembl:ENSMUSG00000061436(gene)|ensembl:ENSMUST00000161779(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010842"(retina layer formation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046332"(SMAD binding)|go:"GO:0046790"(virion binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9QZR5|reactome:R-MMU-3899300|reactome:R-MMU-6804756|reactome:R-MMU-8939243|reactome:R-MMU-9022692|refseq:NP_001281072.1|refseq:NP_001281073.1|dip:DIP-31712N go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045595"(regulation of cell differentiation) - crc64:5C863BE377F3AAEF comment:"Interaction requires repeats 2 and 3 of the Myb DNA-binding domain (IPR001005)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/06/10 2014/10/16 rogid:BHCfLLes3QMOQXPc0SgbXNPldhw10090 rogid:QuwURfphVnnlJdiKOk6l4fDgtQM10090 intact-crc:F1B1FB64B94F2BD6|rigid:qKN/04zu5dIvhriJDNdxgQc5RS0 false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O54949 uniprotkb:Q9QZR5 intact:EBI-366894|uniprotkb:Q6PF98|uniprotkb:Q5SYE6|ensembl:ENSMUSP00000119345 intact:EBI-366905|uniprotkb:O88905|uniprotkb:Q99P45|uniprotkb:Q99P46|uniprotkb:Q9D2E6|uniprotkb:Q9D474|uniprotkb:Q9EQL2|uniprotkb:Q9QZR4|ensembl:ENSMUSP00000124133 psi-mi:nlk_mouse(display_long)|uniprotkb:Nlk(gene name)|psi-mi:Nlk(display_short)|uniprotkb:Nemo-like kinase(gene name synonym) psi-mi:hipk2_mouse(display_long)|uniprotkb:Hipk2(gene name)|psi-mi:Hipk2(display_short)|uniprotkb:Nbak1(gene name synonym)|uniprotkb:Stank(gene name synonym)|uniprotkb:Nuclear body-associated kinase 1(gene name synonym)|uniprotkb:Sialophorin tail-associated nuclear serine/threonine-protein kinase(gene name synonym) psi-mi:"MI:0096"(pull down) Kanei-Ishii et al. (2004) pubmed:15082531 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-366957 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032728.3|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042501"(serine phosphorylation of STAT protein)|ensembl:ENSMUSG00000017376(gene)|ensembl:ENSMUST00000142739(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-MMU-4086398 refseq:NP_001129537.1|refseq:NP_034563.2|ensembl:ENSMUSG00000061436|ensembl:ENSMUSG00000061436(gene)|ensembl:ENSMUST00000161779(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010842"(retina layer formation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046332"(SMAD binding)|go:"GO:0046790"(virion binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9QZR5|reactome:R-MMU-3899300|reactome:R-MMU-6804756|reactome:R-MMU-8939243|reactome:R-MMU-9022692|refseq:NP_001281072.1|refseq:NP_001281073.1|dip:DIP-31712N go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway) - crc64:5C863BE377F3AAEF dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/06/10 2014/10/16 rogid:hoiMW9ZcjnQXDyaFlxEHS9064a010090 rogid:QuwURfphVnnlJdiKOk6l4fDgtQM10090 intact-crc:BA11AB52143F48D7|rigid:ybSR1otJ6/A4MvaHC4yiZKS8qFU false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O54949 uniprotkb:P06876 intact:EBI-366894|uniprotkb:Q6PF98|uniprotkb:Q5SYE6|ensembl:ENSMUSP00000119345 intact:EBI-366934|uniprotkb:Q61929|uniprotkb:E9QMG8|ensembl:ENSMUSP00000020158 psi-mi:nlk_mouse(display_long)|uniprotkb:Nlk(gene name)|psi-mi:Nlk(display_short)|uniprotkb:Nemo-like kinase(gene name synonym) psi-mi:myb_mouse(display_long)|uniprotkb:Myb(gene name)|psi-mi:Myb(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:"MI:0096"(pull down) Kanei-Ishii et al. (2004) pubmed:15082531 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-366965 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032728.3|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042501"(serine phosphorylation of STAT protein)|ensembl:ENSMUSG00000017376(gene)|ensembl:ENSMUST00000142739(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-MMU-4086398 refseq:NP_001185843.1|refseq:NP_034978.3|rcsb pdb:1MBE|rcsb pdb:1MBF|rcsb pdb:1MBG|rcsb pdb:1MBH|rcsb pdb:1MBJ|rcsb pdb:1MBK|rcsb pdb:1MSE|rcsb pdb:1MSF|rcsb pdb:1SB0|rcsb pdb:2AGH|rcsb pdb:6DMX|rcsb pdb:6DNQ|rcsb pdb:1IDZ|ensembl:ENSMUSG00000019982(gene)|ensembl:ENSMUST00000020158(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017145"(stem cell division)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|rcsb pdb:1GUU|rcsb pdb:1GV2|rcsb pdb:1GV5|rcsb pdb:1GVD|rcsb pdb:1H88|rcsb pdb:1H89|rcsb pdb:1IDY|dip:DIP-31713N go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045595"(regulation of cell differentiation) - - comment:"Interaction requires repeat 2 and 3 of the Myb DNA binding domain (IPR001005)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/06/10 2014/10/16 rogid:hoiMW9ZcjnQXDyaFlxEHS9064a010090 rogid:BHCfLLes3QMOQXPc0SgbXNPldhw10090 intact-crc:01E8B2B7F9CF0170|rigid:mMc1Fa8A9vHou/Oct+TFCwm3H3c false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UBE8 uniprotkb:P10242 intact:EBI-366978|uniprotkb:Q6P2A3|uniprotkb:Q2PNI9|uniprotkb:B2RCX1|ensembl:ENSP00000384625 intact:EBI-298355|uniprotkb:P78391|uniprotkb:P78392|uniprotkb:P78525|uniprotkb:P78526|uniprotkb:Q14023|uniprotkb:Q14024|uniprotkb:Q9UE83|uniprotkb:Q708E4|uniprotkb:Q708E7|ensembl:ENSP00000356788|uniprotkb:E9PNL6|uniprotkb:E9PI07|uniprotkb:E9PLZ5|uniprotkb:E9PNA4|uniprotkb:E9PRS2 psi-mi:nlk_human(display_long)|uniprotkb:NLK(gene name)|psi-mi:NLK(display_short)|uniprotkb:LAK1(gene name synonym)|uniprotkb:Nemo-like kinase(gene name synonym)|uniprotkb:Protein LAK1(gene name synonym) psi-mi:myb_human(display_long)|uniprotkb:MYB(gene name)|psi-mi:MYB(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Kanei-Ishii et al. (2004) pubmed:15082531 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-366987 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087095(gene)|ensembl:ENST00000407008(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|refseq:NP_057315.3|go:"GO:0008134"(transcription factor binding)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042501"(serine phosphorylation of STAT protein)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-HSA-4086398 refseq:NP_001155129.1|refseq:NP_001155130.1|refseq:NP_001155131.1|refseq:NP_001155132.1|refseq:NP_001123644.1|refseq:NP_001123645.1|refseq:NP_005366.2|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1904899"(positive regulation of hepatic stellate cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000845"(positive regulation of testosterone secretion)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|mint:P10242|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000118513(gene)|ensembl:ENST00000367814(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|refseq:NP_001155128.1|dip:DIP-1057N go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway) - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:9606(human-molt-4)|taxid:9606(Homo sapiens MOLT-4 T-cell leukaemia line) - 2004/06/10 2014/10/16 rogid:RKKD4tTtOkk3Ve2gevJOI1N69ks9606 rogid:do/bvngcNTqnh1KZE4vDAtPP0749606 intact-crc:0DE71452C0EF563A|rigid:eM4Fnf/V9TPlyJnsRqcjSm5/vA0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P10242 uniprotkb:Q9H2X6 intact:EBI-298355|uniprotkb:P78391|uniprotkb:P78392|uniprotkb:P78525|uniprotkb:P78526|uniprotkb:Q14023|uniprotkb:Q14024|uniprotkb:Q9UE83|uniprotkb:Q708E4|uniprotkb:Q708E7|ensembl:ENSP00000356788|uniprotkb:E9PNL6|uniprotkb:E9PI07|uniprotkb:E9PLZ5|uniprotkb:E9PNA4|uniprotkb:E9PRS2 intact:EBI-348345|ensembl:ENSP00000385571|uniprotkb:Q75MR7|uniprotkb:Q8WWI4|uniprotkb:Q9H2Y1 psi-mi:myb_human(display_long)|uniprotkb:MYB(gene name)|psi-mi:MYB(display_short)|uniprotkb:Proto-oncogene c-Myb(gene name synonym) psi-mi:hipk2_human(display_long)|uniprotkb:HIPK2(gene name)|psi-mi:HIPK2(display_short) psi-mi:"MI:0019"(coimmunoprecipitation) Kanei-Ishii et al. (2004) pubmed:15082531 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-366992 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155129.1|refseq:NP_001155130.1|refseq:NP_001155131.1|refseq:NP_001155132.1|refseq:NP_001123644.1|refseq:NP_001123645.1|refseq:NP_005366.2|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:1901533"(negative regulation of hematopoietic progenitor cell differentiation)|go:"GO:1904899"(positive regulation of hepatic stellate cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000845"(positive regulation of testosterone secretion)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR012642(Mitotic Wos2)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|mint:P10242|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-983231|ensembl:ENSG00000118513(gene)|ensembl:ENST00000367814(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045624"(positive regulation of T-helper cell differentiation)|refseq:NP_001155128.1|dip:DIP-1057N go:"GO:0030578"(PML body organization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046332"(SMAD binding)|go:"GO:0046790"(virion binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|rcsb pdb:6P5S|rcsb pdb:7NCF|reactome:R-HSA-2032785|reactome:R-HSA-3899300|reactome:R-HSA-5578768|reactome:R-HSA-6804756|reactome:R-HSA-8939243|reactome:R-HSA-9022692|mint:Q9H2X6|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010842"(retina layer formation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|ensembl:ENSG00000064393(gene)|ensembl:ENST00000406875(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0001654"(eye development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001106710.1|refseq:NP_073577.3|ensembl:ENSP00000385571|ensembl:ENST00000428878|ensembl:ENSP00000413724|dip:DIP-31716N go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045595"(regulation of cell differentiation) - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:9606(human-molt-4)|taxid:9606(Homo sapiens MOLT-4 T-cell leukaemia line) - 2004/06/10 2014/10/16 rogid:do/bvngcNTqnh1KZE4vDAtPP0749606 rogid:jCklf83jA3PA1CGAimi3q9E9CW49606 intact-crc:F3D8737C3A0F8F07|rigid:y0B9u2CGDEFCdHoOY7g9dTxIIIw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)