#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q96FX2 uniprotkb:Q9UGK8 intact:EBI-465363|ensembl:ENSP00000419599 intact:EBI-465368|uniprotkb:Q9UGK9|ensembl:ENSP00000265965 psi-mi:dph3_human(display_long)|uniprotkb:DESR1(gene name synonym)|uniprotkb:DPH3(gene name)|psi-mi:DPH3(display_short)|uniprotkb:CSL-type zinc finger-containing protein 2(gene name synonym)|uniprotkb:DelGEF-interacting protein 1(gene name synonym)|uniprotkb:ZCSL2(gene name synonym) psi-mi:srgef_human(display_long)|uniprotkb:SERGEF(gene name)|psi-mi:SERGEF(display_short)|uniprotkb:DELGEF(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor-related protein(gene name synonym)|uniprotkb:Deafness locus-associated putative guanine nucleotide exchange factor(gene name synonym)|uniprotkb:GNEFR(gene name synonym) psi-mi:"MI:0018"(two hybrid) Sjolinder et al. (2004) pubmed:14980502 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-465397 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000154813(gene)|ensembl:ENST00000488423(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0046872"(metal ion binding)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051099"(positive regulation of binding)|interpro:IPR007872(Zinc finger, DPH-type)|interpro:IPR036671|interpro:IPR044248|rcsb pdb:2JR7|reactome:R-HSA-5358493|refseq:NP_001040899.1|refseq:NP_996662.1 ensembl:ENST00000265965(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0050709"(negative regulation of protein secretion)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:Q9UGK8|ensembl:ENSG00000129158(gene)|refseq:NP_036271.1 - - - dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/12/06 2014/10/16 rogid:CS4NPRwE45s9Jxz4WJ2U5pDrzjI9606 rogid:3+CMCq/X3/IP+yj7Tp3p+tOvKto9606 intact-crc:9D41CBC22C74E302|rigid:vAxxnyjc90Uw90qz79ql3zYn9FA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96FX2 uniprotkb:Q9UGK8 intact:EBI-465363|ensembl:ENSP00000419599 intact:EBI-465368|uniprotkb:Q9UGK9|ensembl:ENSP00000265965 psi-mi:dph3_human(display_long)|uniprotkb:DESR1(gene name synonym)|uniprotkb:DPH3(gene name)|psi-mi:DPH3(display_short)|uniprotkb:CSL-type zinc finger-containing protein 2(gene name synonym)|uniprotkb:DelGEF-interacting protein 1(gene name synonym)|uniprotkb:ZCSL2(gene name synonym) psi-mi:srgef_human(display_long)|uniprotkb:SERGEF(gene name)|psi-mi:SERGEF(display_short)|uniprotkb:DELGEF(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor-related protein(gene name synonym)|uniprotkb:Deafness locus-associated putative guanine nucleotide exchange factor(gene name synonym)|uniprotkb:GNEFR(gene name synonym) psi-mi:"MI:0018"(two hybrid) Sjolinder et al. (2004) pubmed:14980502 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-465439 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000154813(gene)|ensembl:ENST00000488423(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0046872"(metal ion binding)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051099"(positive regulation of binding)|interpro:IPR007872(Zinc finger, DPH-type)|interpro:IPR036671|interpro:IPR044248|rcsb pdb:2JR7|reactome:R-HSA-5358493|refseq:NP_001040899.1|refseq:NP_996662.1 ensembl:ENST00000265965(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0050709"(negative regulation of protein secretion)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:Q9UGK8|ensembl:ENSG00000129158(gene)|refseq:NP_036271.1 - - - dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/12/06 2014/10/16 rogid:CS4NPRwE45s9Jxz4WJ2U5pDrzjI9606 rogid:3+CMCq/X3/IP+yj7Tp3p+tOvKto9606 intact-crc:57B0C104050C38E6|rigid:vAxxnyjc90Uw90qz79ql3zYn9FA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UGK8 uniprotkb:Q96FX2 intact:EBI-465368|uniprotkb:Q9UGK9|ensembl:ENSP00000265965 intact:EBI-465363|ensembl:ENSP00000419599 psi-mi:srgef_human(display_long)|uniprotkb:SERGEF(gene name)|psi-mi:SERGEF(display_short)|uniprotkb:DELGEF(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor-related protein(gene name synonym)|uniprotkb:Deafness locus-associated putative guanine nucleotide exchange factor(gene name synonym)|uniprotkb:GNEFR(gene name synonym) psi-mi:dph3_human(display_long)|uniprotkb:DESR1(gene name synonym)|uniprotkb:DPH3(gene name)|psi-mi:DPH3(display_short)|uniprotkb:CSL-type zinc finger-containing protein 2(gene name synonym)|uniprotkb:DelGEF-interacting protein 1(gene name synonym)|uniprotkb:ZCSL2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sjolinder et al. (2004) pubmed:14980502 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-465463 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000265965(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0050709"(negative regulation of protein secretion)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:Q9UGK8|ensembl:ENSG00000129158(gene)|refseq:NP_036271.1 ensembl:ENSG00000154813(gene)|ensembl:ENST00000488423(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0046872"(metal ion binding)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051099"(positive regulation of binding)|interpro:IPR007872(Zinc finger, DPH-type)|interpro:IPR036671|interpro:IPR044248|rcsb pdb:2JR7|reactome:R-HSA-5358493|refseq:NP_001040899.1|refseq:NP_996662.1 - - - dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2004/12/06 2014/10/16 rogid:3+CMCq/X3/IP+yj7Tp3p+tOvKto9606 rogid:CS4NPRwE45s9Jxz4WJ2U5pDrzjI9606 intact-crc:9D959D0C57E88CBE|rigid:vAxxnyjc90Uw90qz79ql3zYn9FA false - flag tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UGK8 uniprotkb:Q96KP1 intact:EBI-465368|uniprotkb:Q9UGK9|ensembl:ENSP00000265965 intact:EBI-465715|uniprotkb:Q5JPC8|uniprotkb:Q96AN6|uniprotkb:Q9NUZ8|uniprotkb:Q9UJM7|ensembl:ENSP00000230449|uniprotkb:B2RBE6 psi-mi:srgef_human(display_long)|uniprotkb:SERGEF(gene name)|psi-mi:SERGEF(display_short)|uniprotkb:DELGEF(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor-related protein(gene name synonym)|uniprotkb:Deafness locus-associated putative guanine nucleotide exchange factor(gene name synonym)|uniprotkb:GNEFR(gene name synonym) psi-mi:exoc2_human(display_long)|uniprotkb:EXOC2(gene name)|psi-mi:EXOC2(display_short)|uniprotkb:SEC5(gene name synonym)|uniprotkb:SEC5L1(gene name synonym)|uniprotkb:Exocyst complex component Sec5(gene name synonym) psi-mi:"MI:0096"(pull down) Sjolinder et al. (2004) pubmed:14980502 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-465724 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000265965(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0050709"(negative regulation of protein secretion)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:Q9UGK8|ensembl:ENSG00000129158(gene)|refseq:NP_036271.1 ensembl:ENSG00000112685(gene)|ensembl:ENST00000230449(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0090543"(Flemming body)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR029175|interpro:IPR039481|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:XP_016866507.1|refseq:XP_016866508.1|refseq:XP_016866509.1|refseq:XP_016866510.1|refseq:XP_016866511.1|refseq:XP_016866512.1|refseq:XP_016866513.1|refseq:NP_060773.3|dip:DIP-31795N - - - stimulant:Addition of ZCSL2 strongly increases the interaction.|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/12/06 2014/10/16 rogid:3+CMCq/X3/IP+yj7Tp3p+tOvKto9606 rogid:7p+4vZ18z6u2PJY0GzbHY+ro0v89606 intact-crc:30CF1E475DA57F2F|rigid:JRHygVLJ3T1jQ6BRBhSh568OFFo false glutathione s tranferase tag:n-n radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)