#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P80294	uniprotkb:Q96KC8	intact:EBI-296567|uniprotkb:B2RUY6|ensembl:ENSP00000330587	intact:EBI-296550|uniprotkb:Q5VX89|uniprotkb:Q9H6B8|uniprotkb:B0YIZ8|ensembl:ENSP00000366179	psi-mi:mt1h_human(display_long)|uniprotkb:MT1H(gene name)|psi-mi:MT1H(display_short)|uniprotkb:Metallothionein-IH(gene name synonym)|uniprotkb:Metallothionein-0(gene name synonym)	psi-mi:dnjc1_human(display_long)|uniprotkb:DNAJC1(gene name)|psi-mi:DNAJC1(display_short)|uniprotkb:DnaJ protein homolog MTJ1(gene name synonym)|uniprotkb:HTJ1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kroczynska et al. (2004)	pubmed:14668352	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-296562	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005942.1|ensembl:ENSG00000205358(gene)|ensembl:ENST00000332374(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071294"(cellular response to zinc ion)|interpro:IPR000006(Metallothionein, vertebrate)|interpro:IPR003019(Metallothionein superfamily, eukaryotic)|interpro:IPR017854(Metallothionein superfamily)|interpro:IPR018064|interpro:IPR023587|reactome:R-HSA-5661231	refseq:NP_071760.2|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR017884|interpro:IPR017930|interpro:IPR018253|interpro:IPR036869|rcsb pdb:2CQQ|rcsb pdb:2CQR|ensembl:ENSG00000136770(gene)|ensembl:ENST00000376980(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|go:"GO:0006457"(protein folding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051087"(chaperone binding)	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/02/16	2014/10/16	rogid:8s9tQaRMzAWAkNfAXrwLjR795NQ9606	rogid:rYAqjvnyqhi9qp+KGQBZ2wjzV4Y9606	intact-crc:5F1846C2FA8D01C8|rigid:fh3CfIZZ3//PB5JiwcaFVvmrdk8	false	-	binding-associated region:242-554	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96KC8	uniprotkb:P01011	intact:EBI-296550|uniprotkb:Q5VX89|uniprotkb:Q9H6B8|uniprotkb:B0YIZ8|ensembl:ENSP00000366179	intact:EBI-296557|uniprotkb:Q9UC47|uniprotkb:Q13703|uniprotkb:Q2TU87|uniprotkb:Q2TU88|uniprotkb:Q59GP9|uniprotkb:Q6LBY8|uniprotkb:Q6LDT7|uniprotkb:Q6NSC9|uniprotkb:Q8N177|uniprotkb:Q96DW8|uniprotkb:Q9UNU9|uniprotkb:B3KVQ7|ensembl:ENSP00000376793|ensembl:ENSP00000376795|ensembl:ENSP00000450540	psi-mi:dnjc1_human(display_long)|uniprotkb:DNAJC1(gene name)|psi-mi:DNAJC1(display_short)|uniprotkb:DnaJ protein homolog MTJ1(gene name synonym)|uniprotkb:HTJ1(gene name synonym)	psi-mi:aact_human(display_long)|uniprotkb:Cell growth-inhibiting gene 24/25 protein(gene name synonym)|uniprotkb:SERPINA3(gene name)|psi-mi:SERPINA3(display_short)|uniprotkb:AACT(gene name synonym)|uniprotkb:GIG24(orf name)|uniprotkb:GIG25(orf name)|uniprotkb:Serpin A3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Kroczynska et al. (2004)	pubmed:14668352	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-296913	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071760.2|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR017884|interpro:IPR017930|interpro:IPR018253|interpro:IPR036869|rcsb pdb:2CQQ|rcsb pdb:2CQR|ensembl:ENSG00000136770(gene)|ensembl:ENST00000376980(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|go:"GO:0006457"(protein folding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051087"(chaperone binding)	go:"GO:0006953"(acute-phase response)|refseq:NP_001076.2|ensembl:ENSG00000196136(gene)|ensembl:ENST00000393078(transcript)|ensembl:ENST00000393080(transcript)|ensembl:ENST00000467132(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|reactome:R-HSA-6798695|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000215(Protease inhibitor I4, serpin)|go:"GO:0006954"(inflammatory response)|interpro:IPR023795|interpro:IPR023796|go:"GO:0010951"(negative regulation of endopeptidase activity)|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01011|rcsb pdb:1AS4|rcsb pdb:1QMN|rcsb pdb:2ACH|rcsb pdb:3CAA|rcsb pdb:3DLW|rcsb pdb:4CAA|rcsb pdb:6HGE|reactome:R-HSA-114608	-	-	-	comment:"SANT2 domain (AA 493-554) of Q96KC8 found necessary for interaction. AA520 and AA554 in Q96KC8 found important for successful interaction.  AA 140-343 of Q9UNU9 used in interaction."	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/02/16	2014/10/16	rogid:rYAqjvnyqhi9qp+KGQBZ2wjzV4Y9606	rogid:LTdrRsWwtOm8QvOWZ4h0SO8EuP09606	intact-crc:87C38AA6E791E2BA|rigid:dv3gVCuBYLHoBnFqmf7ta7IPsg4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96KC8	uniprotkb:P01011	intact:EBI-296550|uniprotkb:Q5VX89|uniprotkb:Q9H6B8|uniprotkb:B0YIZ8|ensembl:ENSP00000366179	intact:EBI-296557|uniprotkb:Q9UC47|uniprotkb:Q13703|uniprotkb:Q2TU87|uniprotkb:Q2TU88|uniprotkb:Q59GP9|uniprotkb:Q6LBY8|uniprotkb:Q6LDT7|uniprotkb:Q6NSC9|uniprotkb:Q8N177|uniprotkb:Q96DW8|uniprotkb:Q9UNU9|uniprotkb:B3KVQ7|ensembl:ENSP00000376793|ensembl:ENSP00000376795|ensembl:ENSP00000450540	psi-mi:dnjc1_human(display_long)|uniprotkb:DNAJC1(gene name)|psi-mi:DNAJC1(display_short)|uniprotkb:DnaJ protein homolog MTJ1(gene name synonym)|uniprotkb:HTJ1(gene name synonym)	psi-mi:aact_human(display_long)|uniprotkb:Cell growth-inhibiting gene 24/25 protein(gene name synonym)|uniprotkb:SERPINA3(gene name)|psi-mi:SERPINA3(display_short)|uniprotkb:AACT(gene name synonym)|uniprotkb:GIG24(orf name)|uniprotkb:GIG25(orf name)|uniprotkb:Serpin A3(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Kroczynska et al. (2004)	pubmed:14668352	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-296923	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071760.2|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR017884|interpro:IPR017930|interpro:IPR018253|interpro:IPR036869|rcsb pdb:2CQQ|rcsb pdb:2CQR|ensembl:ENSG00000136770(gene)|ensembl:ENST00000376980(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|go:"GO:0006457"(protein folding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051087"(chaperone binding)	go:"GO:0006953"(acute-phase response)|refseq:NP_001076.2|ensembl:ENSG00000196136(gene)|ensembl:ENST00000393078(transcript)|ensembl:ENST00000393080(transcript)|ensembl:ENST00000467132(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|reactome:R-HSA-6798695|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000215(Protease inhibitor I4, serpin)|go:"GO:0006954"(inflammatory response)|interpro:IPR023795|interpro:IPR023796|go:"GO:0010951"(negative regulation of endopeptidase activity)|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01011|rcsb pdb:1AS4|rcsb pdb:1QMN|rcsb pdb:2ACH|rcsb pdb:3CAA|rcsb pdb:3DLW|rcsb pdb:4CAA|rcsb pdb:6HGE|reactome:R-HSA-114608	-	-	-	comment:Interaction detected by monoclonal antibody to Q9UNU9  AA 493-554 of Q96KC8 and AA1-400 of Q9UNU9 used for interaction.  AA497 and AA520 of Q96KC8 important for successful interaction.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/02/16	2014/10/16	rogid:rYAqjvnyqhi9qp+KGQBZ2wjzV4Y9606	rogid:LTdrRsWwtOm8QvOWZ4h0SO8EuP09606	intact-crc:6A0E6F9A78B6FB3A|rigid:dv3gVCuBYLHoBnFqmf7ta7IPsg4	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q96KC8	uniprotkb:P01011	intact:EBI-296550|uniprotkb:Q5VX89|uniprotkb:Q9H6B8|uniprotkb:B0YIZ8|ensembl:ENSP00000366179	intact:EBI-296557|uniprotkb:Q9UC47|uniprotkb:Q13703|uniprotkb:Q2TU87|uniprotkb:Q2TU88|uniprotkb:Q59GP9|uniprotkb:Q6LBY8|uniprotkb:Q6LDT7|uniprotkb:Q6NSC9|uniprotkb:Q8N177|uniprotkb:Q96DW8|uniprotkb:Q9UNU9|uniprotkb:B3KVQ7|ensembl:ENSP00000376793|ensembl:ENSP00000376795|ensembl:ENSP00000450540	psi-mi:dnjc1_human(display_long)|uniprotkb:DNAJC1(gene name)|psi-mi:DNAJC1(display_short)|uniprotkb:DnaJ protein homolog MTJ1(gene name synonym)|uniprotkb:HTJ1(gene name synonym)	psi-mi:aact_human(display_long)|uniprotkb:Cell growth-inhibiting gene 24/25 protein(gene name synonym)|uniprotkb:SERPINA3(gene name)|psi-mi:SERPINA3(display_short)|uniprotkb:AACT(gene name synonym)|uniprotkb:GIG24(orf name)|uniprotkb:GIG25(orf name)|uniprotkb:Serpin A3(gene name synonym)	psi-mi:"MI:0401"(biochemical)	Kroczynska et al. (2004)	pubmed:14668352	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-296931	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071760.2|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR017884|interpro:IPR017930|interpro:IPR018253|interpro:IPR036869|rcsb pdb:2CQQ|rcsb pdb:2CQR|ensembl:ENSG00000136770(gene)|ensembl:ENST00000376980(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|go:"GO:0006457"(protein folding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051087"(chaperone binding)	go:"GO:0006953"(acute-phase response)|refseq:NP_001076.2|ensembl:ENSG00000196136(gene)|ensembl:ENST00000393078(transcript)|ensembl:ENST00000393080(transcript)|ensembl:ENST00000467132(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|reactome:R-HSA-6798695|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000215(Protease inhibitor I4, serpin)|go:"GO:0006954"(inflammatory response)|interpro:IPR023795|interpro:IPR023796|go:"GO:0010951"(negative regulation of endopeptidase activity)|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01011|rcsb pdb:1AS4|rcsb pdb:1QMN|rcsb pdb:2ACH|rcsb pdb:3CAA|rcsb pdb:3DLW|rcsb pdb:4CAA|rcsb pdb:6HGE|reactome:R-HSA-114608	go:"GO:0030569"(obsolete chymotrypsin inhibitor activity)	-	-	comment:"The SANT2 domain (AA 493-554)of Q96KC8 used for interaction.  AA 497 and 520 of Q96KC8 were found to be important for the interaction.   Interaction not SDS-resistant.  Monoclonal antibody for Q9UNU9 used for detection."	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/02/16	2014/10/16	rogid:rYAqjvnyqhi9qp+KGQBZ2wjzV4Y9606	rogid:LTdrRsWwtOm8QvOWZ4h0SO8EuP09606	intact-crc:00EA27CFC81959EF|rigid:dv3gVCuBYLHoBnFqmf7ta7IPsg4	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)