#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P35609 uniprotkb:Q9Y561 intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5 intact:EBI-296693|uniprotkb:B4DRQ2|uniprotkb:A8K137|ensembl:ENSP00000276654 psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym) psi-mi:lrp12_human(display_long)|uniprotkb:ST7(gene name synonym)|uniprotkb:LRP12(gene name)|psi-mi:LRP12(display_short)|uniprotkb:Suppressor of tumorigenicity 7 protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Battle et al. (2003) pubmed:12809483 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-296713 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N refseq:NP_001129175.1|refseq:NP_038465.1|ensembl:ENSG00000147650(gene)|ensembl:ENST00000276654(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0040008"(regulation of growth)|interpro:IPR000859(CUB)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR035914|interpro:IPR036055|reactome:R-HSA-975634 - - - comment:AA 517-859 of ST7 and AA 307-COOH of ACTN2 are sufficient for this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/02/19 2014/10/16 rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606 rogid:If6W5MknSGJo7Jx7ZcLHHI3tvrI9606 intact-crc:0F0CA8612B3E1F46|rigid:Vtlw/Epjja87AMZp2sBOWBuYJdA false binding-associated region:307-892 binding-associated region:517-589 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UBF9 uniprotkb:Q9Y561 intact:EBI-296701|uniprotkb:A0A4R6|uniprotkb:B4DT79 intact:EBI-296693|uniprotkb:B4DRQ2|uniprotkb:A8K137|ensembl:ENSP00000276654 psi-mi:myoti_human(display_long)|uniprotkb:MYOT(gene name)|psi-mi:MYOT(display_short)|uniprotkb:TTID(gene name synonym)|uniprotkb:Titin immunoglobulin domain protein(gene name synonym)|uniprotkb:Myofibrillar titin-like Ig domains protein(gene name synonym)|uniprotkb:57 kDa cytoskeletal protein(gene name synonym) psi-mi:lrp12_human(display_long)|uniprotkb:ST7(gene name synonym)|uniprotkb:LRP12(gene name)|psi-mi:LRP12(display_short)|uniprotkb:Suppressor of tumorigenicity 7 protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Battle et al. (2003) pubmed:12809483 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-296720 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030424"(axon)|go:"GO:0042383"(sarcolemma)|go:"GO:0043025"(neuronal cell body)|go:"GO:0050808"(synapse organization)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0030018"(Z disc)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001129412.1|refseq:NP_006781.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|rcsb pdb:2KDG|rcsb pdb:2KKQ|refseq:NP_001287840.1|interpro:IPR036179 refseq:NP_001129175.1|refseq:NP_038465.1|ensembl:ENSG00000147650(gene)|ensembl:ENST00000276654(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0040008"(regulation of growth)|interpro:IPR000859(CUB)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR035914|interpro:IPR036055|reactome:R-HSA-975634 - - - comment:AA 517-859 of ST7 and AA 250-COOH of TTID are sufficient fo this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/02/19 2014/10/16 rogid:y7p/HY416pf0hNjpo0B5cRolBAk9606 rogid:If6W5MknSGJo7Jx7ZcLHHI3tvrI9606 intact-crc:93267F15AD54C6F8|rigid:b8T0uHT+LE5YCd36VK1Frnf3BYA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y561 uniprotkb:O95295 intact:EBI-296693|uniprotkb:B4DRQ2|uniprotkb:A8K137|ensembl:ENSP00000276654 intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56 psi-mi:lrp12_human(display_long)|uniprotkb:ST7(gene name synonym)|uniprotkb:LRP12(gene name)|psi-mi:LRP12(display_short)|uniprotkb:Suppressor of tumorigenicity 7 protein(gene name synonym) psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Battle et al. (2003) pubmed:12809483 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-296734 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129175.1|refseq:NP_038465.1|ensembl:ENSG00000147650(gene)|ensembl:ENST00000276654(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0040008"(regulation of growth)|interpro:IPR000859(CUB)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR035914|interpro:IPR036055|reactome:R-HSA-975634 ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1 - - - comment:AA 517-859 of ST7 and AA 17-COOH of SNAP25BP are sufficient for this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/02/19 2014/10/16 rogid:If6W5MknSGJo7Jx7ZcLHHI3tvrI9606 rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606 intact-crc:6B88E5F18C71868C|rigid:sVv0C2rwXIBRC3TPWrxfv+7G8C0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y561 uniprotkb:P63244 intact:EBI-296693|uniprotkb:B4DRQ2|uniprotkb:A8K137|ensembl:ENSP00000276654 intact:EBI-296739|ensembl:ENSP00000426909|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0 psi-mi:lrp12_human(display_long)|uniprotkb:ST7(gene name synonym)|uniprotkb:LRP12(gene name)|psi-mi:LRP12(display_short)|uniprotkb:Suppressor of tumorigenicity 7 protein(gene name synonym) psi-mi:rack1_human(display_long)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym) psi-mi:"MI:0018"(two hybrid) Battle et al. (2003) pubmed:12809483 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-296801 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129175.1|refseq:NP_038465.1|ensembl:ENSG00000147650(gene)|ensembl:ENST00000276654(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0040008"(regulation of growth)|interpro:IPR000859(CUB)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR035914|interpro:IPR036055|reactome:R-HSA-975634 rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|mint:P63244|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|ensembl:ENSG00000204628(gene)|ensembl:ENST00000512805(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|rcsb pdb:6ZUO|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_006089.1|dip:DIP-46736N go:"GO:0007165"(signal transduction) - - comment:AA 517-579 of ST7 and AA 106-COOH of GNB2L1 are sufficient for this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/02/19 2014/10/16 rogid:If6W5MknSGJo7Jx7ZcLHHI3tvrI9606 rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606 intact-crc:8E5730C0A6E0B01F|rigid:o4OhcKSh3jWZ9JLgePSD9h39yJs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NPI5 uniprotkb:Q9Y561 intact:EBI-514059|uniprotkb:Q52M81|uniprotkb:B7ZKR3|uniprotkb:Q9NZK3|ensembl:ENSP00000168977 intact:EBI-296693|uniprotkb:B4DRQ2|uniprotkb:A8K137|ensembl:ENSP00000276654 psi-mi:nrk2_human(display_long)|uniprotkb:NMRK2(gene name)|psi-mi:NMRK2(display_short)|uniprotkb:ITGB1BP3(gene name synonym)|uniprotkb:Integrin beta-1-binding protein 3(gene name synonym)|uniprotkb:Muscle integrin-binding protein(gene name synonym)|uniprotkb:NRK2(gene name synonym)|uniprotkb:Nicotinic acid riboside kinase 2(gene name synonym)|uniprotkb:Ribosylnicotinamide kinase 2(gene name synonym)|uniprotkb:Ribosylnicotinic acid kinase 2(gene name synonym) psi-mi:lrp12_human(display_long)|uniprotkb:ST7(gene name synonym)|uniprotkb:LRP12(gene name)|psi-mi:LRP12(display_short)|uniprotkb:Suppressor of tumorigenicity 7 protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Battle et al. (2003) pubmed:12809483 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-296814 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276046.1|refseq:NP_733778.1|ensembl:ENSG00000077009(gene)|ensembl:ENST00000168977(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050262"(ribosylnicotinamide kinase activity)|go:"GO:0061769"(ribosylnicotinate kinase activity)|interpro:IPR027417|reactome:R-HSA-196807 refseq:NP_001129175.1|refseq:NP_038465.1|ensembl:ENSG00000147650(gene)|ensembl:ENST00000276654(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0040008"(regulation of growth)|interpro:IPR000859(CUB)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR035914|interpro:IPR036055|reactome:R-HSA-975634 go:"GO:0007165"(signal transduction) - - comment:AA 517-579 of ST7 and AA 92-COOH of MIBP are sufficient for this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/02/19 2014/10/16 rogid:ZH0x0zysFbhcQPMhqVSPdjSuQcQ9606 rogid:If6W5MknSGJo7Jx7ZcLHHI3tvrI9606 intact-crc:D337F5048322262E|rigid:0klV727+hnQKpWwVNdUlN6xKEsU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y561 uniprotkb:O95405 intact:EBI-296693|uniprotkb:B4DRQ2|uniprotkb:A8K137|ensembl:ENSP00000276654 intact:EBI-296817|ensembl:ENSP00000287727|ensembl:ENSP00000360647|uniprotkb:Q9UNE1|uniprotkb:Q9Y5R7|uniprotkb:Q5T0F6|uniprotkb:Q5T0F7 psi-mi:lrp12_human(display_long)|uniprotkb:ST7(gene name synonym)|uniprotkb:LRP12(gene name)|psi-mi:LRP12(display_short)|uniprotkb:Suppressor of tumorigenicity 7 protein(gene name synonym) psi-mi:zfyv9_human(display_long)|uniprotkb:ZFYVE9(gene name)|psi-mi:ZFYVE9(display_short)|uniprotkb:MADHIP(gene name synonym)|uniprotkb:SARA(gene name synonym)|uniprotkb:SMADIP(gene name synonym)|uniprotkb:Mothers against decapentaplegic homolog-interacting protein(gene name synonym)|uniprotkb:Smad anchor for receptor activation(gene name synonym)|uniprotkb:Receptor activation anchor(gene name synonym)|uniprotkb:Novel serine protease(gene name synonym) psi-mi:"MI:0018"(two hybrid) Battle et al. (2003) pubmed:12809483 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-296833 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129175.1|refseq:NP_038465.1|ensembl:ENSG00000147650(gene)|ensembl:ENST00000276654(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0040008"(regulation of growth)|interpro:IPR000859(CUB)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR035914|interpro:IPR036055|reactome:R-HSA-975634 ensembl:ENSG00000157077(gene)|ensembl:ENST00000287727(transcript)|ensembl:ENST00000371591(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR024608|interpro:IPR035438|interpro:IPR037145|mint:O95405|rcsb pdb:1DEV|rcsb pdb:1MK2|rcsb pdb:4BKW|rcsb pdb:5MJY|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-3304356|reactome:R-HSA-3656532|refseq:NP_004790.2|refseq:NP_015563.2|refseq:XP_011540739.1 go:"GO:0007165"(signal transduction)|go:"GO:0006897"(endocytosis) - - comment:AA 517-579 of ST7 and AA 731-COOH of MADHIP are sufficient for this interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/02/19 2014/10/16 rogid:If6W5MknSGJo7Jx7ZcLHHI3tvrI9606 rogid:v3GnwyZAswVd59VtF27Ny2k7Ujc9606 intact-crc:7EF5338E7597A1EB|rigid:GwdTHmC3K7qR0s8VRiUDdzkOlU8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63244 uniprotkb:Q9Y561 intact:EBI-296739|ensembl:ENSP00000426909|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0 intact:EBI-296693|uniprotkb:B4DRQ2|uniprotkb:A8K137|ensembl:ENSP00000276654 psi-mi:rack1_human(display_long)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym) psi-mi:lrp12_human(display_long)|uniprotkb:ST7(gene name synonym)|uniprotkb:LRP12(gene name)|psi-mi:LRP12(display_short)|uniprotkb:Suppressor of tumorigenicity 7 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Battle et al. (2003) pubmed:12809483 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-296839 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|mint:P63244|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|ensembl:ENSG00000204628(gene)|ensembl:ENST00000512805(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|rcsb pdb:6ZUO|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_006089.1|dip:DIP-46736N refseq:NP_001129175.1|refseq:NP_038465.1|ensembl:ENSG00000147650(gene)|ensembl:ENST00000276654(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0040008"(regulation of growth)|interpro:IPR000859(CUB)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR035914|interpro:IPR036055|reactome:R-HSA-975634 go:"GO:0007165"(signal transduction) - - comment:Coexpression in 293-T cells. ST7 was V5/His tagged and GNB2L1 was HA tagged. AA 106-COOH of GNB2L1 is sufficient for interaction with ST7.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2004/02/19 2014/10/16 rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606 rogid:If6W5MknSGJo7Jx7ZcLHHI3tvrI9606 intact-crc:6C14C88286380244|rigid:o4OhcKSh3jWZ9JLgePSD9h39yJs false - - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q9NPI5 uniprotkb:Q9Y561 intact:EBI-514059|uniprotkb:Q52M81|uniprotkb:B7ZKR3|uniprotkb:Q9NZK3|ensembl:ENSP00000168977 intact:EBI-296693|uniprotkb:B4DRQ2|uniprotkb:A8K137|ensembl:ENSP00000276654 psi-mi:nrk2_human(display_long)|uniprotkb:NMRK2(gene name)|psi-mi:NMRK2(display_short)|uniprotkb:ITGB1BP3(gene name synonym)|uniprotkb:Integrin beta-1-binding protein 3(gene name synonym)|uniprotkb:Muscle integrin-binding protein(gene name synonym)|uniprotkb:NRK2(gene name synonym)|uniprotkb:Nicotinic acid riboside kinase 2(gene name synonym)|uniprotkb:Ribosylnicotinamide kinase 2(gene name synonym)|uniprotkb:Ribosylnicotinic acid kinase 2(gene name synonym) psi-mi:lrp12_human(display_long)|uniprotkb:ST7(gene name synonym)|uniprotkb:LRP12(gene name)|psi-mi:LRP12(display_short)|uniprotkb:Suppressor of tumorigenicity 7 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Battle et al. (2003) pubmed:12809483 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-296847 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276046.1|refseq:NP_733778.1|ensembl:ENSG00000077009(gene)|ensembl:ENST00000168977(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050262"(ribosylnicotinamide kinase activity)|go:"GO:0061769"(ribosylnicotinate kinase activity)|interpro:IPR027417|reactome:R-HSA-196807 refseq:NP_001129175.1|refseq:NP_038465.1|ensembl:ENSG00000147650(gene)|ensembl:ENST00000276654(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0040008"(regulation of growth)|interpro:IPR000859(CUB)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR035914|interpro:IPR036055|reactome:R-HSA-975634 go:"GO:0007165"(signal transduction) - - comment:Coexpression in 293-T cells. ST7 was V5/His tagged and MIBP was HA tagged. AA 92-COOH of MIBP is sufficient for interaction with ST7.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2004/02/19 2014/10/16 rogid:ZH0x0zysFbhcQPMhqVSPdjSuQcQ9606 rogid:If6W5MknSGJo7Jx7ZcLHHI3tvrI9606 intact-crc:A7CE40D46F7A0100|rigid:0klV727+hnQKpWwVNdUlN6xKEsU false - - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q9Y561 uniprotkb:O95405 intact:EBI-296693|uniprotkb:B4DRQ2|uniprotkb:A8K137|ensembl:ENSP00000276654 intact:EBI-296817|ensembl:ENSP00000287727|ensembl:ENSP00000360647|uniprotkb:Q9UNE1|uniprotkb:Q9Y5R7|uniprotkb:Q5T0F6|uniprotkb:Q5T0F7 psi-mi:lrp12_human(display_long)|uniprotkb:ST7(gene name synonym)|uniprotkb:LRP12(gene name)|psi-mi:LRP12(display_short)|uniprotkb:Suppressor of tumorigenicity 7 protein(gene name synonym) psi-mi:zfyv9_human(display_long)|uniprotkb:ZFYVE9(gene name)|psi-mi:ZFYVE9(display_short)|uniprotkb:MADHIP(gene name synonym)|uniprotkb:SARA(gene name synonym)|uniprotkb:SMADIP(gene name synonym)|uniprotkb:Mothers against decapentaplegic homolog-interacting protein(gene name synonym)|uniprotkb:Smad anchor for receptor activation(gene name synonym)|uniprotkb:Receptor activation anchor(gene name synonym)|uniprotkb:Novel serine protease(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Battle et al. (2003) pubmed:12809483 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-296852 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129175.1|refseq:NP_038465.1|ensembl:ENSG00000147650(gene)|ensembl:ENST00000276654(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0040008"(regulation of growth)|interpro:IPR000859(CUB)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR035914|interpro:IPR036055|reactome:R-HSA-975634 ensembl:ENSG00000157077(gene)|ensembl:ENST00000287727(transcript)|ensembl:ENST00000371591(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR024608|interpro:IPR035438|interpro:IPR037145|mint:O95405|rcsb pdb:1DEV|rcsb pdb:1MK2|rcsb pdb:4BKW|rcsb pdb:5MJY|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-3304356|reactome:R-HSA-3656532|refseq:NP_004790.2|refseq:NP_015563.2|refseq:XP_011540739.1 go:"GO:0007165"(signal transduction)|go:"GO:0006897"(endocytosis) - - comment:Coexpression in 293-T cells. ST7 was V5/His tagged and MADHIP was HA tagged. AA 731-COOH is sufficient for interaction with ST7.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2004/02/19 2014/10/16 rogid:If6W5MknSGJo7Jx7ZcLHHI3tvrI9606 rogid:v3GnwyZAswVd59VtF27Ny2k7Ujc9606 intact-crc:512A0EAB4B9A9160|rigid:GwdTHmC3K7qR0s8VRiUDdzkOlU8 false - - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot)