#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0CG63 uniprotkb:P36075 intact:EBI-7000452|ensemblfungi:YLL039C|intact:MINT-545233|uniprotkb:D6VXW7|uniprotkb:P61864|uniprotkb:Q6LA96|uniprotkb:P04838 intact:EBI-26782|uniprotkb:D6VXJ8|ensemblfungi:YKL090W psi-mi:ubi4p_yeast(display_long)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name) psi-mi:cue2_yeast(display_long)|uniprotkb:CUE2(gene name)|psi-mi:CUE2(display_short)|uniprotkb:YKL090W(locus name)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 2(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Kang et al. (2003) pubmed:12787503|mint:MINT-5216430 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8656399|mint:MINT-24762 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLL039C(gene)|ensemblfungi:YLL039C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:2KDI|rcsb pdb:2L00|rcsb pdb:3CMM|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3OLM|rcsb pdb:4HCN|rcsb pdb:4NNJ|rcsb pdb:4Q5E|rcsb pdb:4Q5H|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-156827|reactome:R-SCE-174113|reactome:R-SCE-1799339|reactome:R-SCE-532668|reactome:R-SCE-5358346|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5687128|reactome:R-SCE-5689603|reactome:R-SCE-5689877|reactome:R-SCE-5689880|reactome:R-SCE-5689901|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6791226|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-72649|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72706|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-8948747|reactome:R-SCE-8948751|reactome:R-SCE-901032|reactome:R-SCE-9020702|reactome:R-SCE-9033241|reactome:R-SCE-917729|reactome:R-SCE-9646399|reactome:R-SCE-975956|reactome:R-SCE-975957|reactome:R-SCE-983168|interpro:IPR000626(Ubiquitin)|sgd:S000003962|interpro:IPR019956|interpro:IPR019954|refseq:NP_013061.1|interpro:IPR029071|mint:P0CG63|mint:MINT-735273(identity) refseq:NP_012833.1|sgd:S000001573|dip:DIP-1917N|ensemblfungi:YKL090W(gene)|ensemblfungi:YKL090W_mRNA(transcript)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|interpro:IPR002625(Smr protein/MutS2 C-terminal)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR036063|interpro:IPR041809|interpro:IPR041810|rcsb pdb:1OTR|mint:MINT-735266(identity) - function:Protein modifier which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Attachment to proteins as a Lys-48-linked polymer usually leads to their degradation by proteasome. Attachment to proteins as a monomer or as an alternatively linked polymer does not lead to proteasomal degradation and may be required for numerous functions, including maintenance of chromatin structure, regulation of gene expression, stress response, ribosome biogenesis and DNA repair|comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint|comment:In the xray complex 1otr, P36075 is chain A and P04838 is chain B Resolution|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/02/12 2014/10/16 rogid:+GNv/Jc7C11q8cgu2qZ6YkcsIeI559292 rogid:x5IYNSbtfMWNa14S0kzmQ5+KJjs559292 intact-crc:F00476DB415661DE|rigid:jahDhx2jU4RGeAeADZWL1ga180g false tag:?-?(MINT-735274) tag:?-?(MINT-735267) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)