#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P16391 uniprotkb:P07151 intact:EBI-8570904|uniprotkb:O02940|intact:MINT-253310 intact:EBI-1031212|ensembl:ENSRNOP00000023017 psi-mi:ha12_rat(display_long) psi-mi:b2mg_rat(display_long)|uniprotkb:B2m(gene name)|psi-mi:B2m(display_short) psi-mi:"MI:0114"(x-ray crystallography) Rudolph et al. (2002) mint:MINT-5215978|pubmed:12470953 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8570926|mint:MINT-24851 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6NF7|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0002476"(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:"GO:0005615"(extracellular space)|go:"GO:0006955"(immune response)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042612"(MHC class I protein complex)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|rcsb pdb:1KJM|interpro:IPR011161(MHC class I-like antigen recognition)|rcsb pdb:1ED3|interpro:IPR036179|interpro:IPR037055|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|mint:MINT-725077(identity) refseq:NP_036644.1|rgd:2189|ensembl:ENSRNOG00000017123(gene)|ensembl:ENSRNOT00000023017(transcript)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0002481"(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007611"(learning or memory)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034756"(regulation of iron ion transport)|go:"GO:0042026"(protein refolding)|go:"GO:0042493"|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071283"("cellular response to iron(III) ion")|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1900122"(positive regulation of receptor binding)|go:"GO:1904434"(positive regulation of ferrous iron binding)|go:"GO:1904437"(positive regulation of transferrin receptor binding)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2000978"(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|rcsb pdb:1ED3|rcsb pdb:1FRT|rcsb pdb:1I1A|rcsb pdb:1KJM|rcsb pdb:1KJV|rcsb pdb:2FRT|rcsb pdb:3FRU|rcsb pdb:6NF7|reactome:R-RNO-1236974|reactome:R-RNO-1236977|reactome:R-RNO-198933|reactome:R-RNO-2172127|reactome:R-RNO-2424491|reactome:R-RNO-6798695|reactome:R-RNO-983170|mint:MINT-725084(identity) - comment:mint|function:Involved in the presentation of foreign antigens to the immune system|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:In the xray complex 1kjm, P16391 is chain A and P07151 is chain B Resolution 2.350|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/02/12 2014/10/16 rogid:Bdw7vjqlgm+n2fqybykoDfIduak10116 rogid:L1E4C8UB88GfVwa4DKn38Q090S410116 intact-crc:D9486AA639164454|rigid:7hG1SFOyZgPXHQsgAf4u884Q/bg false tag:?-?(MINT-725078) tag:?-?(MINT-725085) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)