#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9P0K1	uniprotkb:Q9NYB9	intact:EBI-1567236|uniprotkb:O75075|uniprotkb:O75076|uniprotkb:Q9P0K2|uniprotkb:Q9UIA1|uniprotkb:Q9UKK2|ensembl:ENSP00000265727	intact:EBI-743598|uniprotkb:Q13147|uniprotkb:Q13249|uniprotkb:Q13801|uniprotkb:Q9BV70|uniprotkb:B4DSN1	psi-mi:ada22_human(display_long)|uniprotkb:Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2(gene name synonym)|uniprotkb:Metalloproteinase-disintegrin ADAM22-3(gene name synonym)|uniprotkb:ADAM22(gene name)|psi-mi:ADAM22(display_short)|uniprotkb:MDC2(gene name synonym)	psi-mi:abi2_human(display_long)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Huang et al. (2002)	pubmed:12463424|mint:MINT-5215962	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8567753|mint:MINT-51035	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR034027|interpro:IPR036436|rcsb pdb:3G5C|rcsb pdb:5Y2Z|rcsb pdb:5Y31|rcsb pdb:7CQF|reactome:R-HSA-5682910|ensembl:ENSG00000008277(gene)|ensembl:ENST00000265727(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007417"(central nervous system development)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030424"(axon)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR013111(EGF, extracellular)|interpro:IPR018358|interpro:IPR024079|refseq:NP_004185.1|refseq:NP_068367.1|refseq:NP_068368.2|refseq:NP_068369.1|mint:MINT-724725(identity)	refseq:NP_001269854.1|refseq:NP_001269855.1|refseq:NP_001269856.1|refseq:NP_005750.4|go:"GO:0005912"(adherens junction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007399"(nervous system development)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031209"(SCAR complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR035726|interpro:IPR036028|interpro:IPR036993|rcsb pdb:2ED0|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:XP_006712248.1|mint:Q9NYB9|dip:DIP-37566N|mint:MINT-724719(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:NFA|negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2004/12/24	2014/10/16	rogid:pEM4mE6AUDeeGEhYogJDkrL2/jU9606	rogid:ceor35u+atlarKgbnb1tTQXcSZQ9606	intact-crc:0F25FCDFD23B4AD2|rigid:RID1mBn0S5FZaXibyd6Ix0wjCtQ	true	tag:?-?(MINT-724726)	tag:?-?(MINT-724720)	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0056"(full identification by DNA sequencing)
uniprotkb:Q9NYB9	uniprotkb:Q61072	intact:EBI-743598|uniprotkb:Q13147|uniprotkb:Q13249|uniprotkb:Q13801|uniprotkb:Q9BV70|uniprotkb:B4DSN1	intact:EBI-77983|uniprotkb:E9QPP2|ensembl:ENSMUSP00000081048|uniprotkb:Q60618|uniprotkb:Q61853|uniprotkb:Q80U94	psi-mi:abi2_human(display_long)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)	psi-mi:adam9_mouse(display_long)|uniprotkb:Adam9(gene name)|psi-mi:Adam9(display_short)|uniprotkb:Kiaa0021(gene name synonym)|uniprotkb:Mdc9(gene name synonym)|uniprotkb:Mltng(gene name synonym)|uniprotkb:Metalloprotease/disintegrin/cysteine-rich protein 9(gene name synonym)|uniprotkb:Myeloma cell metalloproteinase(gene name synonym)|uniprotkb:Meltrin-gamma(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Huang et al. (2002)	pubmed:12463424|mint:MINT-5215962	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8567827|mint:MINT-51037	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269854.1|refseq:NP_001269855.1|refseq:NP_001269856.1|refseq:NP_005750.4|go:"GO:0005912"(adherens junction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007399"(nervous system development)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031209"(SCAR complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR035726|interpro:IPR036028|interpro:IPR036993|rcsb pdb:2ED0|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:XP_006712248.1|mint:Q9NYB9|dip:DIP-37566N|mint:MINT-724758(identity)	ensembl:ENSMUSG00000031555(gene)|ensembl:ENSMUST00000084035(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016485"(protein processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0031293"(membrane protein intracellular domain proteolysis)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042117"(monocyte activation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043236"(laminin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902945"(metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|refseq:NP_031430.2|mint:MINT-724764(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:NFA|negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2004/12/24	2014/10/16	rogid:ceor35u+atlarKgbnb1tTQXcSZQ9606	rogid:GSTKev8sg5lfwupVNEpPkPhFxHA10090	intact-crc:518D3FE369272047|rigid:Yt1gWK6v+3YIkyhnD5BhqUlvPXk	true	tag:?-?(MINT-724759)	tag:?-?(MINT-724765)	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0056"(full identification by DNA sequencing)
uniprotkb:Q9UKF5	uniprotkb:Q9NYB9	intact:EBI-8567781|ensembl:ENSP00000352177|ensembl:ENSP00000384229|ensembl:ENSP00000414544|ensembl:ENSP00000423517|ensembl:ENSP00000478469|ensembl:ENSP00000484862|uniprotkb:Q9UHP1|intact:MINT-252736|uniprotkb:Q4W5F3|uniprotkb:Q9UKF3|uniprotkb:Q9UKF4	intact:EBI-743598|uniprotkb:Q13147|uniprotkb:Q13249|uniprotkb:Q13801|uniprotkb:Q9BV70|uniprotkb:B4DSN1	psi-mi:ada29_human(display_long)|uniprotkb:ADAM29(gene name)|psi-mi:ADAM29(display_short)|uniprotkb:Cancer/testis antigen 73(gene name synonym)	psi-mi:abi2_human(display_long)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Huang et al. (2002)	pubmed:12463424|mint:MINT-5215962	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8567774|mint:MINT-51036	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000168594(gene)|ensembl:ENST00000359240(transcript)|ensembl:ENST00000404450(transcript)|ensembl:ENST00000445694(transcript)|ensembl:ENST00000514159(transcript)|ensembl:ENST00000615367(transcript)|ensembl:ENST00000618444(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:1990913"(sperm head plasma membrane)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|refseq:XP_011529859.1|refseq:XP_011529861.1|refseq:XP_011529862.1|refseq:XP_011529863.1|refseq:XP_011529858.1|ensembl:ENSP00000352177|ensembl:ENSP00000384229|ensembl:ENSP00000414544|ensembl:ENSP00000423517|ensembl:ENSP00000478469|ensembl:ENSP00000484862|refseq:NP_001124177.1|refseq:NP_055084.3|refseq:NP_001124176.1|refseq:NP_001124175.1|refseq:NP_001265054.1|refseq:NP_001265055.1|refseq:NP_001265056.1|mint:MINT-724694(identity)	refseq:NP_001269854.1|refseq:NP_001269855.1|refseq:NP_001269856.1|refseq:NP_005750.4|go:"GO:0005912"(adherens junction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007399"(nervous system development)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019900"(kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031209"(SCAR complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR035726|interpro:IPR036028|interpro:IPR036993|rcsb pdb:2ED0|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:XP_006712248.1|mint:Q9NYB9|dip:DIP-37566N|mint:MINT-724688(identity)	-	comment:mint|function:May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:NFA|negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true|dataset:Virus - Publications including interactions involving viral proteins	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2004/12/24	2014/10/16	rogid:19E77bw/6KqbspfB+MLuo+4ZQnM9606	rogid:ceor35u+atlarKgbnb1tTQXcSZQ9606	intact-crc:109AA99D6D87AF49|rigid:NKWDwrP0mhbrm62wENQhLTgbDP4	true	tag:?-?(MINT-724695)	tag:?-?(MINT-724689)	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0056"(full identification by DNA sequencing)