#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q13868	uniprotkb:Q9NPD3	intact:EBI-301735|uniprotkb:Q9NUY4|uniprotkb:A3KFL3|ensembl:ENSP00000361433|uniprotkb:A3KFL4|uniprotkb:B4DKK6	intact:EBI-371823|ensembl:ENSP00000315476	psi-mi:exos2_human(display_long)|uniprotkb:EXOSC2(gene name)|psi-mi:EXOSC2(display_short)|uniprotkb:RRP4(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:Exosome component 2(gene name synonym)	psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Raijmakers et al. (2002)	pubmed:12419256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-371832	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055100.2|ensembl:ENSG00000130713(gene)|ensembl:ENST00000372358(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|mint:Q13868|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001269638.1|dip:DIP-31264N|refseq:NP_001269637.1	refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N	go:"GO:0000178"("exosome (RNase complex)")	-	-	-	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2004/07/13	2014/10/16	rogid:Lpl4OBbEYV2DRbYzLCPvbQdtaro9606	rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606	intact-crc:8A620F8187381115|rigid:b/Z0y0gCOLvFy95kXmv3BLLFdXk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NPD3	uniprotkb:Q13868	intact:EBI-371823|ensembl:ENSP00000315476	intact:EBI-301735|uniprotkb:Q9NUY4|uniprotkb:A3KFL3|ensembl:ENSP00000361433|uniprotkb:A3KFL4|uniprotkb:B4DKK6	psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym)	psi-mi:exos2_human(display_long)|uniprotkb:EXOSC2(gene name)|psi-mi:EXOSC2(display_short)|uniprotkb:RRP4(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:Exosome component 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Raijmakers et al. (2002)	pubmed:12419256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-371837	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N	refseq:NP_055100.2|ensembl:ENSG00000130713(gene)|ensembl:ENST00000372358(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|mint:Q13868|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001269638.1|dip:DIP-31264N|refseq:NP_001269637.1	go:"GO:0000178"("exosome (RNase complex)")	-	-	-	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2004/07/13	2014/10/16	rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606	rogid:Lpl4OBbEYV2DRbYzLCPvbQdtaro9606	intact-crc:4BA8A7AEB475AFE6|rigid:b/Z0y0gCOLvFy95kXmv3BLLFdXk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13868	uniprotkb:Q15024	intact:EBI-301735|uniprotkb:Q9NUY4|uniprotkb:A3KFL3|ensembl:ENSP00000361433|uniprotkb:A3KFL4|uniprotkb:B4DKK6	intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564	psi-mi:exos2_human(display_long)|uniprotkb:EXOSC2(gene name)|psi-mi:EXOSC2(display_short)|uniprotkb:RRP4(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:Exosome component 2(gene name synonym)	psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Raijmakers et al. (2002)	pubmed:12419256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-371852	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055100.2|ensembl:ENSG00000130713(gene)|ensembl:ENST00000372358(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|mint:Q13868|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001269638.1|dip:DIP-31264N|refseq:NP_001269637.1	refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N	go:"GO:0000178"("exosome (RNase complex)")	-	-	-	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2004/07/13	2014/10/16	rogid:Lpl4OBbEYV2DRbYzLCPvbQdtaro9606	rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606	intact-crc:FB3FE6108D191F76|rigid:RsqNVI6Km7KBO/B+AyR1ZlRrwKI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15024	uniprotkb:Q13868	intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564	intact:EBI-301735|uniprotkb:Q9NUY4|uniprotkb:A3KFL3|ensembl:ENSP00000361433|uniprotkb:A3KFL4|uniprotkb:B4DKK6	psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym)	psi-mi:exos2_human(display_long)|uniprotkb:EXOSC2(gene name)|psi-mi:EXOSC2(display_short)|uniprotkb:RRP4(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:Exosome component 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Raijmakers et al. (2002)	pubmed:12419256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-371857	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N	refseq:NP_055100.2|ensembl:ENSG00000130713(gene)|ensembl:ENST00000372358(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|mint:Q13868|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001269638.1|dip:DIP-31264N|refseq:NP_001269637.1	go:"GO:0000178"("exosome (RNase complex)")	-	-	-	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2004/07/13	2014/10/16	rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606	rogid:Lpl4OBbEYV2DRbYzLCPvbQdtaro9606	intact-crc:3AF54E3FBE54A185|rigid:RsqNVI6Km7KBO/B+AyR1ZlRrwKI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NPD3	uniprotkb:Q15024	intact:EBI-371823|ensembl:ENSP00000315476	intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564	psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym)	psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Raijmakers et al. (2002)	pubmed:12419256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-371861	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N	refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N	go:"GO:0000178"("exosome (RNase complex)")	-	-	comment:Arbitary assigment made of bait/roles since not defined by author - only that interaction seen in one direction only.	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2004/07/13	2014/10/16	rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606	rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606	intact-crc:2CAE86B0B0672473|rigid:uw/GdLkr2G8tDQs9+Rb2jEo0x90	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NQT5	uniprotkb:Q9NQT4	intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6	intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233	psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym)	psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Raijmakers et al. (2002)	pubmed:12419256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-371887	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N	refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N	go:"GO:0000178"("exosome (RNase complex)")	-	-	comment:Arbitary assigment made of bait/roles since not defined by author - only that interaction seen in one direction only.	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2004/07/13	2014/10/16	rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606	rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606	intact-crc:0E1D3B512C874DC0|rigid:VBefDYKJyBrpbs6+qO0P151IAHQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15024	uniprotkb:Q9Y3B2	intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym)	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Raijmakers et al. (2002)	pubmed:12419256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-371904	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	go:"GO:0000178"("exosome (RNase complex)")	-	-	-	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2004/07/13	2014/10/16	rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	intact-crc:31A679888007213D|rigid:ytBi10yHXCpc6IB4jyxSAtHTrIs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y3B2	uniprotkb:Q15024	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Raijmakers et al. (2002)	pubmed:12419256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-371908	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N	go:"GO:0000178"("exosome (RNase complex)")	-	-	-	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2004/07/13	2014/10/16	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606	intact-crc:F06CD1A7B34A9FCE|rigid:ytBi10yHXCpc6IB4jyxSAtHTrIs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NQT4	uniprotkb:Q9Y3B2	intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym)	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Raijmakers et al. (2002)	pubmed:12419256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-371914	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	go:"GO:0000178"("exosome (RNase complex)")	-	-	-	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2004/07/13	2014/10/16	rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	intact-crc:E463999E9314A794|rigid:g4l1Xa47ej5OzCFmRa1UR7MkUek	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y3B2	uniprotkb:Q9NQT4	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Raijmakers et al. (2002)	pubmed:12419256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-371918	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N	go:"GO:0000178"("exosome (RNase complex)")	-	-	-	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2004/07/13	2014/10/16	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606	intact-crc:25A931B1A0591967|rigid:g4l1Xa47ej5OzCFmRa1UR7MkUek	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NQT4	uniprotkb:Q96B26	intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233	intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354	psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym)	psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Raijmakers et al. (2002)	pubmed:12419256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-371928	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N	refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N	go:"GO:0000178"("exosome (RNase complex)")	-	-	-	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2004/07/13	2014/10/16	rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606	rogid:y/cReHiPMubzNruyETohBjbRick9606	intact-crc:169E8B98BEB8832B|rigid:XTt1uv/Gosk07KcjsAaT6EDg+n4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96B26	uniprotkb:Q9NQT4	intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354	intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233	psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym)	psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Raijmakers et al. (2002)	pubmed:12419256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-371933	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N	refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N	go:"GO:0000178"("exosome (RNase complex)")	-	-	-	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2004/07/13	2014/10/16	rogid:y/cReHiPMubzNruyETohBjbRick9606	rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606	intact-crc:D75423B78DF53DD8|rigid:XTt1uv/Gosk07KcjsAaT6EDg+n4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13615	uniprotkb:Q15024	intact:EBI-371938|uniprotkb:Q9NYN5|uniprotkb:Q9NYN6|uniprotkb:Q9UDX6|uniprotkb:Q9UEG3|uniprotkb:A5PL26|uniprotkb:A7MD32|intact:EBI-28971617|ensembl:ENSP00000384651	intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564	psi-mi:mtmr3_human(display_long)|uniprotkb:MTMR3(gene name)|psi-mi:MTMR3(display_short)|uniprotkb:FYVE domain-containing dual specificity protein phosphatase 1(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 10(gene name synonym)|uniprotkb:KIAA0371(gene name synonym)|uniprotkb:ZFYVE10(gene name synonym)|uniprotkb:Phosphatidylinositol-3,5-bisphosphate 3-phosphatase(gene name synonym)|uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym)	psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Raijmakers et al. (2002)	pubmed:12419256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-371975	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000333027|ensembl:ENSP00000331649|ensembl:ENST00000351488|ensembl:ENSP00000307271|ensembl:ENSP00000384651|ensembl:ENST00000406629|ensembl:ENSP00000384077|refseq:NP_066576.1|refseq:NP_694690.1|refseq:NP_694691.1|ensembl:ENSG00000100330(gene)|ensembl:ENST00000401950(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:1904562"(phosphatidylinositol 5-phosphate metabolic process)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR029021|interpro:IPR030564|interpro:IPR035888|mint:Q13615|reactome:R-HSA-1632852|reactome:R-HSA-1660499|refseq:XP_016884521.1	refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N	go:"GO:0000178"("exosome (RNase complex)")	-	-	-	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2004/07/13	2014/10/16	rogid:6YquGTCQYgFfrhdj1Iqtzgd9tP49606	rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606	intact-crc:D5357DD42A457BE6|rigid:k8EFpXMvLanyN9rDzZ9Zo1KqbaU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13615	uniprotkb:Q15024	intact:EBI-371938|uniprotkb:Q9NYN5|uniprotkb:Q9NYN6|uniprotkb:Q9UDX6|uniprotkb:Q9UEG3|uniprotkb:A5PL26|uniprotkb:A7MD32|intact:EBI-28971617|ensembl:ENSP00000384651	intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564	psi-mi:mtmr3_human(display_long)|uniprotkb:MTMR3(gene name)|psi-mi:MTMR3(display_short)|uniprotkb:FYVE domain-containing dual specificity protein phosphatase 1(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 10(gene name synonym)|uniprotkb:KIAA0371(gene name synonym)|uniprotkb:ZFYVE10(gene name synonym)|uniprotkb:Phosphatidylinositol-3,5-bisphosphate 3-phosphatase(gene name synonym)|uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym)	psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Raijmakers et al. (2002)	pubmed:12419256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-371979	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000333027|ensembl:ENSP00000331649|ensembl:ENST00000351488|ensembl:ENSP00000307271|ensembl:ENSP00000384651|ensembl:ENST00000406629|ensembl:ENSP00000384077|refseq:NP_066576.1|refseq:NP_694690.1|refseq:NP_694691.1|ensembl:ENSG00000100330(gene)|ensembl:ENST00000401950(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:1904562"(phosphatidylinositol 5-phosphate metabolic process)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR029021|interpro:IPR030564|interpro:IPR035888|mint:Q13615|reactome:R-HSA-1632852|reactome:R-HSA-1660499|refseq:XP_016884521.1	refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N	go:"GO:0000178"("exosome (RNase complex)")	-	-	-	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2004/07/13	2014/10/16	rogid:6YquGTCQYgFfrhdj1Iqtzgd9tP49606	rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606	intact-crc:14FFD5FB1908C515|rigid:k8EFpXMvLanyN9rDzZ9Zo1KqbaU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y3B2	uniprotkb:Q13615	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	intact:EBI-371938|uniprotkb:Q9NYN5|uniprotkb:Q9NYN6|uniprotkb:Q9UDX6|uniprotkb:Q9UEG3|uniprotkb:A5PL26|uniprotkb:A7MD32|intact:EBI-28971617|ensembl:ENSP00000384651	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:mtmr3_human(display_long)|uniprotkb:MTMR3(gene name)|psi-mi:MTMR3(display_short)|uniprotkb:FYVE domain-containing dual specificity protein phosphatase 1(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 10(gene name synonym)|uniprotkb:KIAA0371(gene name synonym)|uniprotkb:ZFYVE10(gene name synonym)|uniprotkb:Phosphatidylinositol-3,5-bisphosphate 3-phosphatase(gene name synonym)|uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Raijmakers et al. (2002)	pubmed:12419256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-371983	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	ensembl:ENST00000333027|ensembl:ENSP00000331649|ensembl:ENST00000351488|ensembl:ENSP00000307271|ensembl:ENSP00000384651|ensembl:ENST00000406629|ensembl:ENSP00000384077|refseq:NP_066576.1|refseq:NP_694690.1|refseq:NP_694691.1|ensembl:ENSG00000100330(gene)|ensembl:ENST00000401950(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:1904562"(phosphatidylinositol 5-phosphate metabolic process)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR029021|interpro:IPR030564|interpro:IPR035888|mint:Q13615|reactome:R-HSA-1632852|reactome:R-HSA-1660499|refseq:XP_016884521.1	go:"GO:0000178"("exosome (RNase complex)")	-	-	-	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2004/07/13	2014/10/16	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	rogid:6YquGTCQYgFfrhdj1Iqtzgd9tP49606	intact-crc:4CD982A44C204CBA|rigid:0HBldQz7pf/Cj97nwYd0vSsti/A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13615	uniprotkb:Q9Y3B2	intact:EBI-371938|uniprotkb:Q9NYN5|uniprotkb:Q9NYN6|uniprotkb:Q9UDX6|uniprotkb:Q9UEG3|uniprotkb:A5PL26|uniprotkb:A7MD32|intact:EBI-28971617|ensembl:ENSP00000384651	intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939	psi-mi:mtmr3_human(display_long)|uniprotkb:MTMR3(gene name)|psi-mi:MTMR3(display_short)|uniprotkb:FYVE domain-containing dual specificity protein phosphatase 1(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 10(gene name synonym)|uniprotkb:KIAA0371(gene name synonym)|uniprotkb:ZFYVE10(gene name synonym)|uniprotkb:Phosphatidylinositol-3,5-bisphosphate 3-phosphatase(gene name synonym)|uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym)	psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Raijmakers et al. (2002)	pubmed:12419256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-371987	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000333027|ensembl:ENSP00000331649|ensembl:ENST00000351488|ensembl:ENSP00000307271|ensembl:ENSP00000384651|ensembl:ENST00000406629|ensembl:ENSP00000384077|refseq:NP_066576.1|refseq:NP_694690.1|refseq:NP_694691.1|ensembl:ENSG00000100330(gene)|ensembl:ENST00000401950(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:1904562"(phosphatidylinositol 5-phosphate metabolic process)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR029021|interpro:IPR030564|interpro:IPR035888|mint:Q13615|reactome:R-HSA-1632852|reactome:R-HSA-1660499|refseq:XP_016884521.1	refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N	go:"GO:0000178"("exosome (RNase complex)")	-	-	-	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2004/07/13	2014/10/16	rogid:6YquGTCQYgFfrhdj1Iqtzgd9tP49606	rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606	intact-crc:8D132A8B7F6DF249|rigid:0HBldQz7pf/Cj97nwYd0vSsti/A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96B26	uniprotkb:Q13615	intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354	intact:EBI-371938|uniprotkb:Q9NYN5|uniprotkb:Q9NYN6|uniprotkb:Q9UDX6|uniprotkb:Q9UEG3|uniprotkb:A5PL26|uniprotkb:A7MD32|intact:EBI-28971617|ensembl:ENSP00000384651	psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym)	psi-mi:mtmr3_human(display_long)|uniprotkb:MTMR3(gene name)|psi-mi:MTMR3(display_short)|uniprotkb:FYVE domain-containing dual specificity protein phosphatase 1(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 10(gene name synonym)|uniprotkb:KIAA0371(gene name synonym)|uniprotkb:ZFYVE10(gene name synonym)|uniprotkb:Phosphatidylinositol-3,5-bisphosphate 3-phosphatase(gene name synonym)|uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Raijmakers et al. (2002)	pubmed:12419256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-371991	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N	ensembl:ENST00000333027|ensembl:ENSP00000331649|ensembl:ENST00000351488|ensembl:ENSP00000307271|ensembl:ENSP00000384651|ensembl:ENST00000406629|ensembl:ENSP00000384077|refseq:NP_066576.1|refseq:NP_694690.1|refseq:NP_694691.1|ensembl:ENSG00000100330(gene)|ensembl:ENST00000401950(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:1904562"(phosphatidylinositol 5-phosphate metabolic process)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR029021|interpro:IPR030564|interpro:IPR035888|mint:Q13615|reactome:R-HSA-1632852|reactome:R-HSA-1660499|refseq:XP_016884521.1	go:"GO:0000178"("exosome (RNase complex)")	-	-	-	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2004/07/13	2014/10/16	rogid:y/cReHiPMubzNruyETohBjbRick9606	rogid:6YquGTCQYgFfrhdj1Iqtzgd9tP49606	intact-crc:45679CE74980F6F7|rigid:bMeVnkOviEVQqhW1DWFeLA8lnD8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13615	uniprotkb:Q96B26	intact:EBI-371938|uniprotkb:Q9NYN5|uniprotkb:Q9NYN6|uniprotkb:Q9UDX6|uniprotkb:Q9UEG3|uniprotkb:A5PL26|uniprotkb:A7MD32|intact:EBI-28971617|ensembl:ENSP00000384651	intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354	psi-mi:mtmr3_human(display_long)|uniprotkb:MTMR3(gene name)|psi-mi:MTMR3(display_short)|uniprotkb:FYVE domain-containing dual specificity protein phosphatase 1(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 10(gene name synonym)|uniprotkb:KIAA0371(gene name synonym)|uniprotkb:ZFYVE10(gene name synonym)|uniprotkb:Phosphatidylinositol-3,5-bisphosphate 3-phosphatase(gene name synonym)|uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym)	psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Raijmakers et al. (2002)	pubmed:12419256	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-371995	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000333027|ensembl:ENSP00000331649|ensembl:ENST00000351488|ensembl:ENSP00000307271|ensembl:ENSP00000384651|ensembl:ENST00000406629|ensembl:ENSP00000384077|refseq:NP_066576.1|refseq:NP_694690.1|refseq:NP_694691.1|ensembl:ENSG00000100330(gene)|ensembl:ENST00000401950(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:1904562"(phosphatidylinositol 5-phosphate metabolic process)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR029021|interpro:IPR030564|interpro:IPR035888|mint:Q13615|reactome:R-HSA-1632852|reactome:R-HSA-1660499|refseq:XP_016884521.1	refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N	go:"GO:0000178"("exosome (RNase complex)")	-	-	-	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2004/07/13	2014/10/16	rogid:6YquGTCQYgFfrhdj1Iqtzgd9tP49606	rogid:y/cReHiPMubzNruyETohBjbRick9606	intact-crc:84AD34C87ACD4804|rigid:bMeVnkOviEVQqhW1DWFeLA8lnD8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)