#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P42124 uniprotkb:P02299 intact:EBI-112315|uniprotkb:Q9VTA3|uniprotkb:B7Z0G2|ensemblmetazoa:FBpp0076008|ensemblmetazoa:FBpp0271846 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 psi-mi:ez_drome(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:"E(z)"(gene name)|psi-mi:"E(z)"(display_short)|uniprotkb:CG6502(orf name)|uniprotkb:Protein enhancer of zeste(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym) psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:"MI:0045"(experimental interaction detection) Czermin et al. (2002) pubmed:12408863|mint:MINT-5215869 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0213"(methylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8553672|mint:MINT-50302 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524021.2|refseq:NP_001137932.1|flybase:FBgn0000629|dip:DIP-20386N|ensemblmetazoa:FBgn0000629(gene)|ensemblmetazoa:FBtr0076279(transcript)|ensemblmetazoa:FBtr0273338(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016571"(histone methylation)|go:"GO:0022008"(neurogenesis)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:P42124|reactome:R-DME-2559580|reactome:R-DME-8943724|mint:MINT-1573672(identity) refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231|mint:MINT-1573677(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/09/10 2014/10/16 rogid:SgDch3Z90h2XcA4b2MqjzZN+gSI7227 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 intact-crc:ECAD36AAC862C951|rigid:hdj8yBxlRK4WhDXQ2QqAhwiUDTI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P02299 uniprotkb:P20659 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 intact:EBI-591327|ensemblmetazoa:FBpp0082406|ensemblmetazoa:FBpp0082409|uniprotkb:Q27255|uniprotkb:Q27327|uniprotkb:Q8INF9|uniprotkb:Q960R2|uniprotkb:Q9VFL1|uniprotkb:A4V2V9|uniprotkb:A4V2W0|intact:EBI-3404288|intact:EBI-3417031|intact:EBI-9922180|intact:EBI-9933604 psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:trx_drome(display_long)|uniprotkb:KMT2A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2A(gene name synonym)|uniprotkb:trx(gene name)|psi-mi:trx(display_short)|uniprotkb:CG8651(orf name)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) Czermin et al. (2002) pubmed:12408863|mint:MINT-5215869 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0213"(methylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8553681|mint:MINT-50314 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231|mint:MINT-1662104(identity) ensemblmetazoa:FBgn0003862(gene)|ensemblmetazoa:FBtr0082947(transcript)|ensemblmetazoa:FBtr0082950(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR001214(SET)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|reactome:R-DME-8936459|reactome:R-DME-8939236|refseq:NP_001014621.1|refseq:NP_476769.1|refseq:NP_476770.1|refseq:NP_599108.1|refseq:NP_599109.1|flybase:FBgn0003862|mint:MINT-1662099(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/09/10 2014/10/16 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 rogid:LDT4/pLaHAuL/kuZMReRH9ZDrNk7227 intact-crc:F733454EEBE6215E|rigid:OgYiskKdpkR6EGkaWsMIvOErFxk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P02299 uniprotkb:P42124 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 intact:EBI-112315|uniprotkb:Q9VTA3|uniprotkb:B7Z0G2|ensemblmetazoa:FBpp0076008|ensemblmetazoa:FBpp0271846 psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:ez_drome(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:"E(z)"(gene name)|psi-mi:"E(z)"(display_short)|uniprotkb:CG6502(orf name)|uniprotkb:Protein enhancer of zeste(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) Czermin et al. (2002) pubmed:12408863|mint:MINT-5215869 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0213"(methylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8553691|mint:MINT-50325 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231|mint:MINT-1573663(identity) refseq:NP_524021.2|refseq:NP_001137932.1|flybase:FBgn0000629|dip:DIP-20386N|ensemblmetazoa:FBgn0000629(gene)|ensemblmetazoa:FBtr0076279(transcript)|ensemblmetazoa:FBtr0273338(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016571"(histone methylation)|go:"GO:0022008"(neurogenesis)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:P42124|reactome:R-DME-2559580|reactome:R-DME-8943724|mint:MINT-1573658(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/09/10 2014/10/16 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 rogid:SgDch3Z90h2XcA4b2MqjzZN+gSI7227 intact-crc:096E6B35DAEC3785|rigid:hdj8yBxlRK4WhDXQ2QqAhwiUDTI false binding-associated region:1-19(MINT-1573664) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P02299 uniprotkb:P42124 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 intact:EBI-112315|uniprotkb:Q9VTA3|uniprotkb:B7Z0G2|ensemblmetazoa:FBpp0076008|ensemblmetazoa:FBpp0271846 psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:ez_drome(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:"E(z)"(gene name)|psi-mi:"E(z)"(display_short)|uniprotkb:CG6502(orf name)|uniprotkb:Protein enhancer of zeste(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) Czermin et al. (2002) pubmed:12408863|mint:MINT-5215869 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0213"(methylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8553704|mint:MINT-50327 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231|mint:MINT-1573628(identity) refseq:NP_524021.2|refseq:NP_001137932.1|flybase:FBgn0000629|dip:DIP-20386N|ensemblmetazoa:FBgn0000629(gene)|ensemblmetazoa:FBtr0076279(transcript)|ensemblmetazoa:FBtr0273338(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016571"(histone methylation)|go:"GO:0022008"(neurogenesis)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:P42124|reactome:R-DME-2559580|reactome:R-DME-8943724|mint:MINT-1573623(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1C|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/09/10 2014/10/16 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 rogid:SgDch3Z90h2XcA4b2MqjzZN+gSI7227 intact-crc:75BD0DAD14392068|rigid:hdj8yBxlRK4WhDXQ2QqAhwiUDTI false mutation decreasing interaction:9-9(MINT-1573631)|binding-associated region:1-19(MINT-1573629) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P42124 uniprotkb:P02299 intact:EBI-112315|uniprotkb:Q9VTA3|uniprotkb:B7Z0G2|ensemblmetazoa:FBpp0076008|ensemblmetazoa:FBpp0271846 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 psi-mi:ez_drome(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:"E(z)"(gene name)|psi-mi:"E(z)"(display_short)|uniprotkb:CG6502(orf name)|uniprotkb:Protein enhancer of zeste(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym) psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:"MI:0045"(experimental interaction detection) Czermin et al. (2002) pubmed:12408863|mint:MINT-5215869 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0213"(methylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8553722|mint:MINT-50328 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524021.2|refseq:NP_001137932.1|flybase:FBgn0000629|dip:DIP-20386N|ensemblmetazoa:FBgn0000629(gene)|ensemblmetazoa:FBtr0076279(transcript)|ensemblmetazoa:FBtr0273338(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016571"(histone methylation)|go:"GO:0022008"(neurogenesis)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:P42124|reactome:R-DME-2559580|reactome:R-DME-8943724|mint:MINT-1573606(identity) refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231|mint:MINT-1573611(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1C|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/09/10 2014/10/16 rogid:SgDch3Z90h2XcA4b2MqjzZN+gSI7227 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 intact-crc:9084DF6F13AEAA20|rigid:hdj8yBxlRK4WhDXQ2QqAhwiUDTI false - monoacetylated residue:9-9(MINT-1573614)|binding-associated region:1-19(MINT-1573612) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P02299 uniprotkb:P42124 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 intact:EBI-112315|uniprotkb:Q9VTA3|uniprotkb:B7Z0G2|ensemblmetazoa:FBpp0076008|ensemblmetazoa:FBpp0271846 psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:ez_drome(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:"E(z)"(gene name)|psi-mi:"E(z)"(display_short)|uniprotkb:CG6502(orf name)|uniprotkb:Protein enhancer of zeste(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) Czermin et al. (2002) pubmed:12408863|mint:MINT-5215869 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0213"(methylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8553740|mint:MINT-50329 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231|mint:MINT-1573645(identity) refseq:NP_524021.2|refseq:NP_001137932.1|flybase:FBgn0000629|dip:DIP-20386N|ensemblmetazoa:FBgn0000629(gene)|ensemblmetazoa:FBtr0076279(transcript)|ensemblmetazoa:FBtr0273338(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016571"(histone methylation)|go:"GO:0022008"(neurogenesis)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:P42124|reactome:R-DME-2559580|reactome:R-DME-8943724|mint:MINT-1573640(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/09/10 2014/10/16 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 rogid:SgDch3Z90h2XcA4b2MqjzZN+gSI7227 intact-crc:DCAA00C399E765F2|rigid:hdj8yBxlRK4WhDXQ2QqAhwiUDTI false N6,N6-dimethyl-L-lysine:9-9(MINT-1573650)|N6,N6-dimethyl-L-lysine:4-4(MINT-1573648)|binding-associated region:1-19(MINT-1573646) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P20659 uniprotkb:P02299 intact:EBI-591327|ensemblmetazoa:FBpp0082406|ensemblmetazoa:FBpp0082409|uniprotkb:Q27255|uniprotkb:Q27327|uniprotkb:Q8INF9|uniprotkb:Q960R2|uniprotkb:Q9VFL1|uniprotkb:A4V2V9|uniprotkb:A4V2W0|intact:EBI-3404288|intact:EBI-3417031|intact:EBI-9922180|intact:EBI-9933604 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 psi-mi:trx_drome(display_long)|uniprotkb:KMT2A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2A(gene name synonym)|uniprotkb:trx(gene name)|psi-mi:trx(display_short)|uniprotkb:CG8651(orf name)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:"MI:0045"(experimental interaction detection) Czermin et al. (2002) pubmed:12408863|mint:MINT-5215869 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0213"(methylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8553817|mint:MINT-50333 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0003862(gene)|ensemblmetazoa:FBtr0082947(transcript)|ensemblmetazoa:FBtr0082950(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR001214(SET)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|reactome:R-DME-8936459|reactome:R-DME-8939236|refseq:NP_001014621.1|refseq:NP_476769.1|refseq:NP_476770.1|refseq:NP_599108.1|refseq:NP_599109.1|flybase:FBgn0003862|mint:MINT-1662126(identity) refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231|mint:MINT-1662131(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" resulting-ptm:acetylation@9|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/09/10 2014/10/16 rogid:LDT4/pLaHAuL/kuZMReRH9ZDrNk7227 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 intact-crc:740643F0EBC96D33|rigid:OgYiskKdpkR6EGkaWsMIvOErFxk false - binding-associated region:1-19(MINT-1662132) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P20659 uniprotkb:P02299 intact:EBI-591327|ensemblmetazoa:FBpp0082406|ensemblmetazoa:FBpp0082409|uniprotkb:Q27255|uniprotkb:Q27327|uniprotkb:Q8INF9|uniprotkb:Q960R2|uniprotkb:Q9VFL1|uniprotkb:A4V2V9|uniprotkb:A4V2W0|intact:EBI-3404288|intact:EBI-3417031|intact:EBI-9922180|intact:EBI-9933604 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 psi-mi:trx_drome(display_long)|uniprotkb:KMT2A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2A(gene name synonym)|uniprotkb:trx(gene name)|psi-mi:trx(display_short)|uniprotkb:CG8651(orf name)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:"MI:0045"(experimental interaction detection) Czermin et al. (2002) pubmed:12408863|mint:MINT-5215869 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0213"(methylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8553832|mint:MINT-50334 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0003862(gene)|ensemblmetazoa:FBtr0082947(transcript)|ensemblmetazoa:FBtr0082950(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR001214(SET)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|reactome:R-DME-8936459|reactome:R-DME-8939236|refseq:NP_001014621.1|refseq:NP_476769.1|refseq:NP_476770.1|refseq:NP_599108.1|refseq:NP_599109.1|flybase:FBgn0003862|mint:MINT-1662141(identity) refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231|mint:MINT-1662146(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" resulting-ptm:acetylation@14|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/09/10 2014/10/16 rogid:LDT4/pLaHAuL/kuZMReRH9ZDrNk7227 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 intact-crc:65858BC3F0EBC96D|rigid:OgYiskKdpkR6EGkaWsMIvOErFxk false - binding-associated region:1-19(MINT-1662147) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P02299 uniprotkb:P20659 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 intact:EBI-591327|ensemblmetazoa:FBpp0082406|ensemblmetazoa:FBpp0082409|uniprotkb:Q27255|uniprotkb:Q27327|uniprotkb:Q8INF9|uniprotkb:Q960R2|uniprotkb:Q9VFL1|uniprotkb:A4V2V9|uniprotkb:A4V2W0|intact:EBI-3404288|intact:EBI-3417031|intact:EBI-9922180|intact:EBI-9933604 psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:trx_drome(display_long)|uniprotkb:KMT2A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2A(gene name synonym)|uniprotkb:trx(gene name)|psi-mi:trx(display_short)|uniprotkb:CG8651(orf name)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) Czermin et al. (2002) pubmed:12408863|mint:MINT-5215869 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0213"(methylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8553802|mint:MINT-50332 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231|mint:MINT-1662116(identity) ensemblmetazoa:FBgn0003862(gene)|ensemblmetazoa:FBtr0082947(transcript)|ensemblmetazoa:FBtr0082950(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR001214(SET)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|reactome:R-DME-8936459|reactome:R-DME-8939236|refseq:NP_001014621.1|refseq:NP_476769.1|refseq:NP_476770.1|refseq:NP_599108.1|refseq:NP_599109.1|flybase:FBgn0003862|mint:MINT-1662111(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" resulting-ptm:N6@N6-dimethyl-L-lysine 9|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/09/10 2014/10/16 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 rogid:LDT4/pLaHAuL/kuZMReRH9ZDrNk7227 intact-crc:FCC19EE26678B877|rigid:OgYiskKdpkR6EGkaWsMIvOErFxk false binding-associated region:1-19(MINT-1662117) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P02299 uniprotkb:P20659 intact:EBI-522090|uniprotkb:Q4ABE4|ensemblmetazoa:FBpp0085250|ensemblmetazoa:FBpp0091051|ensemblmetazoa:FBpp0091053|ensemblmetazoa:FBpp0091056|ensemblmetazoa:FBpp0091058|ensemblmetazoa:FBpp0091061|ensemblmetazoa:FBpp0091064|ensemblmetazoa:FBpp0091067|ensemblmetazoa:FBpp0091070|ensemblmetazoa:FBpp0091073|ensemblmetazoa:FBpp0091076|ensemblmetazoa:FBpp0091079|ensemblmetazoa:FBpp0091082|ensemblmetazoa:FBpp0091085|ensemblmetazoa:FBpp0091088|ensemblmetazoa:FBpp0091091|ensemblmetazoa:FBpp0091094|ensemblmetazoa:FBpp0091097|ensemblmetazoa:FBpp0091100|ensemblmetazoa:FBpp0091103|ensemblmetazoa:FBpp0091106|ensemblmetazoa:FBpp0091109|ensemblmetazoa:FBpp0091112 intact:EBI-591327|ensemblmetazoa:FBpp0082406|ensemblmetazoa:FBpp0082409|uniprotkb:Q27255|uniprotkb:Q27327|uniprotkb:Q8INF9|uniprotkb:Q960R2|uniprotkb:Q9VFL1|uniprotkb:A4V2V9|uniprotkb:A4V2W0|intact:EBI-3404288|intact:EBI-3417031|intact:EBI-9922180|intact:EBI-9933604 psi-mi:h3_drome(display_long)|uniprotkb:His3(gene name)|psi-mi:His3(display_short)|uniprotkb:"His3:CG31613"(gene name)|psi-mi:"His3:CG31613"(display_short)|uniprotkb:"His3:CG33857"(gene name)|psi-mi:"His3:CG33857"(display_short)|uniprotkb:"His3:CG33860"(gene name)|psi-mi:"His3:CG33860"(display_short)|uniprotkb:"His3:CG33863"(gene name)|psi-mi:"His3:CG33863"(display_short)|uniprotkb:"His3:CG33866"(gene name)|psi-mi:"His3:CG33866"(display_short)|uniprotkb:CG31613(orf name)|uniprotkb:CG33803(orf name)|uniprotkb:CG33806(orf name)|uniprotkb:CG33809(orf name)|uniprotkb:CG33812(orf name)|uniprotkb:CG33815(orf name)|uniprotkb:CG33818(orf name)|uniprotkb:CG33821(orf name)|uniprotkb:CG33824(orf name)|uniprotkb:CG33827(orf name)|uniprotkb:CG33830(orf name)|uniprotkb:CG33833(orf name)|uniprotkb:CG33836(orf name)|uniprotkb:CG33839(orf name)|uniprotkb:CG33842(orf name)|uniprotkb:CG33845(orf name)|uniprotkb:CG33848(orf name)|uniprotkb:CG33851(orf name)|uniprotkb:CG33854(orf name)|uniprotkb:CG33857(orf name)|uniprotkb:CG33860(orf name)|uniprotkb:CG33863(orf name)|uniprotkb:CG33866(orf name)|uniprotkb:"His3:CG33803"(gene name)|psi-mi:"His3:CG33803"(display_short)|uniprotkb:"His3:CG33806"(gene name)|psi-mi:"His3:CG33806"(display_short)|uniprotkb:"His3:CG33809"(gene name)|psi-mi:"His3:CG33809"(display_short)|uniprotkb:"His3:CG33812"(gene name)|psi-mi:"His3:CG33812"(display_short)|uniprotkb:"His3:CG33815"(gene name)|psi-mi:"His3:CG33815"(display_short)|uniprotkb:"His3:CG33818"(gene name)|psi-mi:"His3:CG33818"(display_short)|uniprotkb:"His3:CG33821"(gene name)|psi-mi:"His3:CG33821"(display_short)|uniprotkb:"His3:CG33824"(gene name)|psi-mi:"His3:CG33824"(display_short)|uniprotkb:"His3:CG33827"(gene name)|psi-mi:"His3:CG33827"(display_short)|uniprotkb:"His3:CG33830"(gene name)|psi-mi:"His3:CG33830"(display_short)|uniprotkb:"His3:CG33833"(gene name)|psi-mi:"His3:CG33833"(display_short)|uniprotkb:"His3:CG33836"(gene name)|psi-mi:"His3:CG33836"(display_short)|uniprotkb:"His3:CG33839"(gene name)|psi-mi:"His3:CG33839"(display_short)|uniprotkb:"His3:CG33842"(gene name)|psi-mi:"His3:CG33842"(display_short)|uniprotkb:"His3:CG33845"(gene name)|psi-mi:"His3:CG33845"(display_short)|uniprotkb:"His3:CG33848"(gene name)|psi-mi:"His3:CG33848"(display_short)|uniprotkb:"His3:CG33851"(gene name)|psi-mi:"His3:CG33851"(display_short)|uniprotkb:"His3:CG33854"(gene name)|psi-mi:"His3:CG33854"(display_short) psi-mi:trx_drome(display_long)|uniprotkb:KMT2A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2A(gene name synonym)|uniprotkb:trx(gene name)|psi-mi:trx(display_short)|uniprotkb:CG8651(orf name)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:"MI:0045"(experimental interaction detection) Czermin et al. (2002) pubmed:12408863|mint:MINT-5215869 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0213"(methylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8553865|mint:MINT-50336 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001027285.1|refseq:NP_001027289.1|refseq:NP_001027294.1|refseq:NP_001027298.1|refseq:NP_001027303.1|refseq:NP_001027308.1|refseq:NP_001027313.1|refseq:NP_001027318.1|refseq:NP_001027323.1|refseq:NP_001027328.1|refseq:NP_001027333.1|refseq:NP_001027338.1|refseq:NP_001027343.1|refseq:NP_001027348.1|refseq:NP_001027353.1|refseq:NP_001027358.1|refseq:NP_001027363.1|refseq:NP_001027368.1|refseq:NP_001027373.1|refseq:NP_001027378.1|refseq:NP_001027383.1|refseq:NP_001027387.1|refseq:NP_724345.1|flybase:FBgn0001199|flybase:FBgn0051613|flybase:FBgn0053803|flybase:FBgn0053806|flybase:FBgn0053809|flybase:FBgn0053812|flybase:FBgn0053815|flybase:FBgn0053818|flybase:FBgn0053821|flybase:FBgn0053824|flybase:FBgn0053827|flybase:FBgn0053830|flybase:FBgn0053833|flybase:FBgn0053836|flybase:FBgn0053839|flybase:FBgn0053842|flybase:FBgn0053845|flybase:FBgn0053848|flybase:FBgn0053851|flybase:FBgn0053854|flybase:FBgn0053857|flybase:FBgn0053860|flybase:FBgn0053863|flybase:FBgn0053866|dip:DIP-38722N|ensemblmetazoa:FBgn0051613(gene)|ensemblmetazoa:FBgn0053803(gene)|ensemblmetazoa:FBgn0053806(gene)|ensemblmetazoa:FBgn0053809(gene)|ensemblmetazoa:FBgn0053812(gene)|ensemblmetazoa:FBgn0053815(gene)|ensemblmetazoa:FBgn0053818(gene)|ensemblmetazoa:FBgn0053821(gene)|ensemblmetazoa:FBgn0053824(gene)|ensemblmetazoa:FBgn0053827(gene)|ensemblmetazoa:FBgn0053830(gene)|ensemblmetazoa:FBgn0053833(gene)|ensemblmetazoa:FBgn0053836(gene)|ensemblmetazoa:FBgn0053839(gene)|ensemblmetazoa:FBgn0053842(gene)|ensemblmetazoa:FBgn0053845(gene)|ensemblmetazoa:FBgn0053848(gene)|ensemblmetazoa:FBgn0053851(gene)|ensemblmetazoa:FBgn0053854(gene)|ensemblmetazoa:FBgn0053857(gene)|ensemblmetazoa:FBgn0053860(gene)|ensemblmetazoa:FBgn0053863(gene)|ensemblmetazoa:FBgn0053866(gene)|ensemblmetazoa:FBtr0085894(transcript)|ensemblmetazoa:FBtr0091807(transcript)|ensemblmetazoa:FBtr0091810(transcript)|ensemblmetazoa:FBtr0091813(transcript)|ensemblmetazoa:FBtr0091816(transcript)|ensemblmetazoa:FBtr0091819(transcript)|ensemblmetazoa:FBtr0091822(transcript)|ensemblmetazoa:FBtr0091825(transcript)|ensemblmetazoa:FBtr0091828(transcript)|ensemblmetazoa:FBtr0091831(transcript)|ensemblmetazoa:FBtr0091834(transcript)|ensemblmetazoa:FBtr0091837(transcript)|ensemblmetazoa:FBtr0091840(transcript)|ensemblmetazoa:FBtr0091843(transcript)|ensemblmetazoa:FBtr0091846(transcript)|ensemblmetazoa:FBtr0091849(transcript)|ensemblmetazoa:FBtr0091852(transcript)|ensemblmetazoa:FBtr0091855(transcript)|ensemblmetazoa:FBtr0091858(transcript)|ensemblmetazoa:FBtr0091861(transcript)|ensemblmetazoa:FBtr0091864(transcript)|ensemblmetazoa:FBtr0091867(transcript)|ensemblmetazoa:FBtr0091870(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0035059"(RCAF complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P02299|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:2NQB|rcsb pdb:2PYO|rcsb pdb:2YBA|rcsb pdb:4QLC|rcsb pdb:4UUZ|rcsb pdb:4X23|rcsb pdb:5WCU|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6DZT|rcsb pdb:6MHA|rcsb pdb:6PWE|rcsb pdb:6PWF|reactome:R-DME-1266695|reactome:R-DME-3214847|reactome:R-DME-3247509|reactome:R-DME-8936459|reactome:R-DME-983231|mint:MINT-1662180(identity) ensemblmetazoa:FBgn0003862(gene)|ensemblmetazoa:FBtr0082947(transcript)|ensemblmetazoa:FBtr0082950(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0007482"(haltere development)|go:"GO:0007507"(heart development)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044665"(MLL1/2 complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|interpro:IPR001214(SET)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|reactome:R-DME-8936459|reactome:R-DME-8939236|refseq:NP_001014621.1|refseq:NP_476769.1|refseq:NP_476770.1|refseq:NP_599108.1|refseq:NP_599109.1|flybase:FBgn0003862|mint:MINT-1662175(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/09/10 2014/10/16 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o7227 rogid:LDT4/pLaHAuL/kuZMReRH9ZDrNk7227 intact-crc:AB1930A1EDA79446|rigid:OgYiskKdpkR6EGkaWsMIvOErFxk false binding-associated region:1-19(MINT-1662181) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0363"(inferred by author)