#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q04207 uniprotkb:P25799 intact:EBI-644400|uniprotkb:Q62025|ensembl:ENSMUSP00000025867 intact:EBI-643958|uniprotkb:B2RRQ6|uniprotkb:Q3TZE8|uniprotkb:Q3V2V6|uniprotkb:Q6TDG8|uniprotkb:Q75ZL1|uniprotkb:Q80Y21|uniprotkb:Q8C712|ensembl:ENSMUSP00000029812|ensembl:ENSMUSP00000128345 psi-mi:tf65_mouse(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:Nfkb3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym) psi-mi:nfkb1_mouse(display_long)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:NF-kappa-B1 p84/NF-kappa-B1 p98(gene name synonym)|uniprotkb:Nfkb1(gene name)|psi-mi:Nfkb1(display_short)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Chen-Park et al. (2002) pubmed:11970949|mint:MINT-5215321 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8307153|mint:MINT-25001 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033071.1|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5621575|reactome:R-MMU-9020702|reactome:R-MMU-933542|rcsb pdb:2RAM|rcsb pdb:5U01|rcsb pdb:6GGR|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|ensembl:ENSMUSG00000024927(gene)|ensembl:ENSMUST00000025867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|mint:Q04207|rcsb pdb:1BFT|rcsb pdb:1IKN|rcsb pdb:1K3Z|rcsb pdb:1LE5|rcsb pdb:1LE9|rcsb pdb:1LEI|rcsb pdb:1MY5|rcsb pdb:1MY7|rcsb pdb:1OY3|rcsb pdb:1RAM|interpro:IPR037059|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2LWW|dip:DIP-6219N|mint:MINT-714334(identity) refseq:NP_032715.2|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048535"(lymph node development)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071322"(cellular response to carbohydrate stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1900127"(positive regulation of hyaluronan biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|rcsb pdb:1U3Y|rcsb pdb:1U3Z|rcsb pdb:1U41|rcsb pdb:1U42|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2V2T|rcsb pdb:3JV4|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-5607764|reactome:R-MMU-5621575|rcsb pdb:1U3J|reactome:R-MMU-5684264|reactome:R-MMU-6798695|ensembl:ENSMUSG00000028163(gene)|ensembl:ENSMUST00000029812(transcript)|ensembl:ENSMUST00000164430(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|refseq:XP_006501169.1|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904630"(cellular response to diterpene)|go:"GO:1904632"(cellular response to glucoside)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030503|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:P25799|rcsb pdb:1BFS|rcsb pdb:1IKN|rcsb pdb:1LE5|rcsb pdb:1LE9|go:"GO:1901653"(cellular response to peptide)|rcsb pdb:1LEI|rcsb pdb:1NFK|rcsb pdb:1OOA|rcsb pdb:1U36|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0010628"(positive regulation of gene expression)|reactome:R-MMU-933542|reactome:R-MMU-9020702|dip:DIP-85N|mint:MINT-714341(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:In the xray complex 1lei, Q04207 is chain A and P25799 is chain B Resolution 2.700|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/02/12 2014/10/16 rogid:poiJSPJwXK2Om5pfk8z5HwFgK1o10090 rogid:OiCZGnyznh4scSRI6QeIuv4pHbA10090 intact-crc:E78F403A67FA24B5|rigid:0AZuFy4V4SHQmESaNIXknOfbw10 false tag:?-?(MINT-714335) tag:?-?(MINT-714342) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)