#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O54960	uniprotkb:Q63537	intact:EBI-780358	intact:EBI-1638355|uniprotkb:Q9Z1H0	psi-mi:capon_rat(display_long)|uniprotkb:Nitric oxide synthase 1 adaptor protein(gene name synonym)|uniprotkb:C-terminal PDZ ligand of neuronal nitric oxide synthase protein(gene name synonym)|uniprotkb:Nos1ap(gene name)|psi-mi:Nos1ap(display_short)|uniprotkb:Capon(gene name synonym)	psi-mi:syn2_rat(display_long)|uniprotkb:Syn2(gene name)|psi-mi:Syn2(display_short)|uniprotkb:Synapsin II(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jaffrey et al. (2002)	pubmed:11867766|mint:MINT-5215146	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8146894|mint:MINT-49631	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:620106|refseq:NP_620277.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR006020(Phosphotyrosine interaction region)|go:"GO:0002020"(protease binding)|go:"GO:0003062"(regulation of heart rate by chemical signal)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0030018"(Z disc)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|mint:MINT-712084(identity)	rgd:3798|refseq:NP_001029192.1|refseq:NP_062032.1|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR001359(Synapsin)|interpro:IPR020898|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|mint:Q63537|interpro:IPR028712|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043195"(terminal bouton)|go:"GO:0045202"(synapse)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099504"(synaptic vesicle cycle)|rcsb pdb:1I7L|rcsb pdb:1I7N|reactome:R-RNO-181429|reactome:R-RNO-212676|mint:MINT-712092(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2004/04/09	2014/10/16	rogid:jVxktgA+vgO6Dy5IaBsFjkItBf810116	rogid:/uqCXVO2VdZfAgfc9c8dwJQcUOY10116	intact-crc:5CD38933F7AC46E2|rigid:v1omUwO6V3rExkLuLl5PyLbci/8	false	tag:?-?(MINT-712087)|binding-associated region:32-170(MINT-712085)	tag:?-?(MINT-712093)	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:O70441	uniprotkb:O54960	intact:EBI-8152619|intact:MINT-232985	intact:EBI-780358	psi-mi:syn3_rat(display_long)|uniprotkb:Syn3(gene name)|psi-mi:Syn3(display_short)|uniprotkb:Synapsin III(gene name synonym)	psi-mi:capon_rat(display_long)|uniprotkb:Nitric oxide synthase 1 adaptor protein(gene name synonym)|uniprotkb:C-terminal PDZ ligand of neuronal nitric oxide synthase protein(gene name synonym)|uniprotkb:Nos1ap(gene name)|psi-mi:Nos1ap(display_short)|uniprotkb:Capon(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jaffrey et al. (2002)	pubmed:11867766|mint:MINT-5215146	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8152608|mint:MINT-49632	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3799|refseq:NP_058805.1|dip:DIP-358N|reactome:R-RNO-181429|reactome:R-RNO-212676|go:"GO:0005524"(ATP binding)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0045202"(synapse)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099504"(synaptic vesicle cycle)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028712|mint:MINT-712076(identity)	rgd:620106|refseq:NP_620277.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR006020(Phosphotyrosine interaction region)|go:"GO:0002020"(protease binding)|go:"GO:0003062"(regulation of heart rate by chemical signal)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0030018"(Z disc)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|mint:MINT-712068(identity)	-	comment:mint|function:May be involved in the regulation of neurotransmitter release and synaptogenesis. Binds ATP with high affinity and ADP with a lower affinity. This is consistent with a catalytic role of the C-domain in which ADP would be dissociated by cellular ATP after bound ATP was hydrolyzed|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2004/04/09	2014/10/16	rogid:eL1BtP/JfRTyAI0bVIUBS08fSIY10116	rogid:jVxktgA+vgO6Dy5IaBsFjkItBf810116	intact-crc:A1E85A96013D9E9D|rigid:UXspFyWhOQam9bwpmZ5GdS1TCiI	false	tag:?-?(MINT-712077)	binding-associated region:32-170(MINT-712069)|tag:?-?(MINT-712071)	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:O54960	uniprotkb:P09951	intact:EBI-780358	intact:EBI-1638487|uniprotkb:Q9WUX7|ensembl:ENSRNOP00000014250	psi-mi:capon_rat(display_long)|uniprotkb:Nitric oxide synthase 1 adaptor protein(gene name synonym)|uniprotkb:C-terminal PDZ ligand of neuronal nitric oxide synthase protein(gene name synonym)|uniprotkb:Nos1ap(gene name)|psi-mi:Nos1ap(display_short)|uniprotkb:Capon(gene name synonym)	psi-mi:syn1_rat(display_long)|uniprotkb:Syn1(gene name)|psi-mi:Syn1(display_short)|uniprotkb:Synapsin I(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jaffrey et al. (2002)	pubmed:11867766|mint:MINT-5215146	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8152682|mint:MINT-49633	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:620106|refseq:NP_620277.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR006020(Phosphotyrosine interaction region)|go:"GO:0002020"(protease binding)|go:"GO:0003062"(regulation of heart rate by chemical signal)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0030018"(Z disc)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|mint:MINT-712120(identity)	rgd:3797|refseq:NP_001104252.1|refseq:NP_062006.1|ensembl:ENSRNOG00000010365(gene)|ensembl:ENSRNOT00000014250(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0045202"(synapse)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048666"(neuron development)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0099504"(synaptic vesicle cycle)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028713|mint:P09951|rcsb pdb:1PK8|rcsb pdb:1PX2|reactome:R-RNO-181429|reactome:R-RNO-212676|mint:MINT-712128(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2004/04/09	2014/10/16	rogid:jVxktgA+vgO6Dy5IaBsFjkItBf810116	rogid:2Kokx9XJDZPkBHu140QPqsDpSxw10116	intact-crc:7069DA8EFA80AE7A|rigid:Jd0OeYsFc8YqUII2eSx9pnls0PE	false	binding-associated region:32-170(MINT-712121)|tag:?-?(MINT-712123)	tag:?-?(MINT-712132)|binding-associated region:200-300(MINT-712129)	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:O54960	uniprotkb:P09951	intact:EBI-780358	intact:EBI-1638487|uniprotkb:Q9WUX7|ensembl:ENSRNOP00000014250	psi-mi:capon_rat(display_long)|uniprotkb:Nitric oxide synthase 1 adaptor protein(gene name synonym)|uniprotkb:C-terminal PDZ ligand of neuronal nitric oxide synthase protein(gene name synonym)|uniprotkb:Nos1ap(gene name)|psi-mi:Nos1ap(display_short)|uniprotkb:Capon(gene name synonym)	psi-mi:syn1_rat(display_long)|uniprotkb:Syn1(gene name)|psi-mi:Syn1(display_short)|uniprotkb:Synapsin I(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Jaffrey et al. (2002)	pubmed:11867766|mint:MINT-5215146	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8152733|mint:MINT-49630	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:620106|refseq:NP_620277.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR006020(Phosphotyrosine interaction region)|go:"GO:0002020"(protease binding)|go:"GO:0003062"(regulation of heart rate by chemical signal)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0030018"(Z disc)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|mint:MINT-712102(identity)	rgd:3797|refseq:NP_001104252.1|refseq:NP_062006.1|ensembl:ENSRNOG00000010365(gene)|ensembl:ENSRNOT00000014250(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0045202"(synapse)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048666"(neuron development)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0099504"(synaptic vesicle cycle)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028713|mint:P09951|rcsb pdb:1PK8|rcsb pdb:1PX2|reactome:R-RNO-181429|reactome:R-RNO-212676|mint:MINT-712110(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:overlay assay?|comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2004/04/09	2014/10/16	rogid:jVxktgA+vgO6Dy5IaBsFjkItBf810116	rogid:2Kokx9XJDZPkBHu140QPqsDpSxw10116	intact-crc:7717124102C859FD|rigid:Jd0OeYsFc8YqUII2eSx9pnls0PE	false	binding-associated region:32-170(MINT-712103)|tag:?-?(MINT-712105)	binding-associated region:200-300(MINT-712111)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)