#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0CG63	uniprotkb:P48510	intact:EBI-7000452|ensemblfungi:YLL039C|intact:MINT-545233|uniprotkb:D6VXW7|uniprotkb:P61864|uniprotkb:Q6LA96|uniprotkb:P04838	intact:EBI-6174|uniprotkb:D6W0A3|ensemblfungi:YMR276W	psi-mi:ubi4p_yeast(display_long)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name)	psi-mi:dsk2_yeast(display_long)|uniprotkb:DSK2(gene name)|psi-mi:DSK2(display_short)|uniprotkb:SHE4(gene name synonym)|uniprotkb:YMR276W(locus name)|uniprotkb:YM8021.02(orf name)	psi-mi:"MI:0096"(pull down)	Funakoshi et al. (2002)	pubmed:11805328|mint:MINT-5215046	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8083438|mint:MINT-50251	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLL039C(gene)|ensemblfungi:YLL039C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:2KDI|rcsb pdb:2L00|rcsb pdb:3CMM|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3OLM|rcsb pdb:4HCN|rcsb pdb:4NNJ|rcsb pdb:4Q5E|rcsb pdb:4Q5H|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-156827|reactome:R-SCE-174113|reactome:R-SCE-1799339|reactome:R-SCE-532668|reactome:R-SCE-5358346|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5687128|reactome:R-SCE-5689603|reactome:R-SCE-5689877|reactome:R-SCE-5689880|reactome:R-SCE-5689901|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6791226|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-72649|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72706|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-8948747|reactome:R-SCE-8948751|reactome:R-SCE-901032|reactome:R-SCE-9020702|reactome:R-SCE-9033241|reactome:R-SCE-917729|reactome:R-SCE-9646399|reactome:R-SCE-975956|reactome:R-SCE-975957|reactome:R-SCE-983168|interpro:IPR000626(Ubiquitin)|sgd:S000003962|interpro:IPR019956|interpro:IPR019954|refseq:NP_013061.1|interpro:IPR029071|mint:P0CG63|mint:MINT-612542(identity)	refseq:NP_014003.1|sgd:S000004889|dip:DIP-4398N|mint:P48510|ensemblfungi:YMR276W(gene)|ensemblfungi:YMR276W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019954|interpro:IPR029071|rcsb pdb:1WR1|rcsb pdb:2BWB|rcsb pdb:2BWE|rcsb pdb:2BWF|rcsb pdb:3M63|rcsb pdb:4UN2|reactome:R-SCE-8856825|mint:MINT-612536(identity)	-	function:Protein modifier which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Attachment to proteins as a Lys-48-linked polymer usually leads to their degradation by proteasome. Attachment to proteins as a monomer or as an alternatively linked polymer does not lead to proteasomal degradation and may be required for numerous functions, including maintenance of chromatin structure, regulation of gene expression, stress response, ribosome biogenesis and DNA repair|comment:mint|comment:"Stoichiometry: 1.0"	crc64:3F8691BB95E46569|comment:"Stoichiometry: 1.0"	comment:Dsk2 binds to polyubiquitin chains but not to monoubiquitin.|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/09/08	2014/10/16	rogid:+GNv/Jc7C11q8cgu2qZ6YkcsIeI559292	rogid:1hHbfo970BiDc/ZuAO8Jc6V9vEI559292	intact-crc:BB257499B83C264F|rigid:YlNIedx16tlOxK6OPSpYFODQ3Zo	false	tag:?-?(MINT-612543)	tag:?-?(MINT-612537)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0CG63	uniprotkb:P48510	intact:EBI-7000452|ensemblfungi:YLL039C|intact:MINT-545233|uniprotkb:D6VXW7|uniprotkb:P61864|uniprotkb:Q6LA96|uniprotkb:P04838	intact:EBI-6174|uniprotkb:D6W0A3|ensemblfungi:YMR276W	psi-mi:ubi4p_yeast(display_long)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name)	psi-mi:dsk2_yeast(display_long)|uniprotkb:DSK2(gene name)|psi-mi:DSK2(display_short)|uniprotkb:SHE4(gene name synonym)|uniprotkb:YMR276W(locus name)|uniprotkb:YM8021.02(orf name)	psi-mi:"MI:0096"(pull down)	Funakoshi et al. (2002)	pubmed:11805328|mint:MINT-5215046	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8083479|mint:MINT-50253	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLL039C(gene)|ensemblfungi:YLL039C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:2KDI|rcsb pdb:2L00|rcsb pdb:3CMM|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3OLM|rcsb pdb:4HCN|rcsb pdb:4NNJ|rcsb pdb:4Q5E|rcsb pdb:4Q5H|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-156827|reactome:R-SCE-174113|reactome:R-SCE-1799339|reactome:R-SCE-532668|reactome:R-SCE-5358346|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5687128|reactome:R-SCE-5689603|reactome:R-SCE-5689877|reactome:R-SCE-5689880|reactome:R-SCE-5689901|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6791226|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-72649|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72706|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-8948747|reactome:R-SCE-8948751|reactome:R-SCE-901032|reactome:R-SCE-9020702|reactome:R-SCE-9033241|reactome:R-SCE-917729|reactome:R-SCE-9646399|reactome:R-SCE-975956|reactome:R-SCE-975957|reactome:R-SCE-983168|interpro:IPR000626(Ubiquitin)|sgd:S000003962|interpro:IPR019956|interpro:IPR019954|refseq:NP_013061.1|interpro:IPR029071|mint:P0CG63|mint:MINT-612569(identity)	refseq:NP_014003.1|sgd:S000004889|dip:DIP-4398N|mint:P48510|ensemblfungi:YMR276W(gene)|ensemblfungi:YMR276W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019954|interpro:IPR029071|rcsb pdb:1WR1|rcsb pdb:2BWB|rcsb pdb:2BWE|rcsb pdb:2BWF|rcsb pdb:3M63|rcsb pdb:4UN2|reactome:R-SCE-8856825|mint:MINT-612575(identity)	-	function:Protein modifier which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Attachment to proteins as a Lys-48-linked polymer usually leads to their degradation by proteasome. Attachment to proteins as a monomer or as an alternatively linked polymer does not lead to proteasomal degradation and may be required for numerous functions, including maintenance of chromatin structure, regulation of gene expression, stress response, ribosome biogenesis and DNA repair|comment:mint|comment:"Stoichiometry: 1.0"	crc64:3F8691BB95E46569|comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/09/08	2014/10/16	rogid:+GNv/Jc7C11q8cgu2qZ6YkcsIeI559292	rogid:1hHbfo970BiDc/ZuAO8Jc6V9vEI559292	intact-crc:109844A08F7E518C|rigid:YlNIedx16tlOxK6OPSpYFODQ3Zo	false	tag:?-?(MINT-612570)	tag:?-?(MINT-612576)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0CG63	uniprotkb:P48510	intact:EBI-7000452|ensemblfungi:YLL039C|intact:MINT-545233|uniprotkb:D6VXW7|uniprotkb:P61864|uniprotkb:Q6LA96|uniprotkb:P04838	intact:EBI-6174|uniprotkb:D6W0A3|ensemblfungi:YMR276W	psi-mi:ubi4p_yeast(display_long)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name)	psi-mi:dsk2_yeast(display_long)|uniprotkb:DSK2(gene name)|psi-mi:DSK2(display_short)|uniprotkb:SHE4(gene name synonym)|uniprotkb:YMR276W(locus name)|uniprotkb:YM8021.02(orf name)	psi-mi:"MI:0096"(pull down)	Funakoshi et al. (2002)	pubmed:11805328|mint:MINT-5215046	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8083456|mint:MINT-50252	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLL039C(gene)|ensemblfungi:YLL039C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:2KDI|rcsb pdb:2L00|rcsb pdb:3CMM|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3OLM|rcsb pdb:4HCN|rcsb pdb:4NNJ|rcsb pdb:4Q5E|rcsb pdb:4Q5H|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-156827|reactome:R-SCE-174113|reactome:R-SCE-1799339|reactome:R-SCE-532668|reactome:R-SCE-5358346|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5687128|reactome:R-SCE-5689603|reactome:R-SCE-5689877|reactome:R-SCE-5689880|reactome:R-SCE-5689901|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6791226|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-72649|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72706|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-8948747|reactome:R-SCE-8948751|reactome:R-SCE-901032|reactome:R-SCE-9020702|reactome:R-SCE-9033241|reactome:R-SCE-917729|reactome:R-SCE-9646399|reactome:R-SCE-975956|reactome:R-SCE-975957|reactome:R-SCE-983168|interpro:IPR000626(Ubiquitin)|sgd:S000003962|interpro:IPR019956|interpro:IPR019954|refseq:NP_013061.1|interpro:IPR029071|mint:P0CG63|mint:MINT-612591(identity)	refseq:NP_014003.1|sgd:S000004889|dip:DIP-4398N|mint:P48510|ensemblfungi:YMR276W(gene)|ensemblfungi:YMR276W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019954|interpro:IPR029071|rcsb pdb:1WR1|rcsb pdb:2BWB|rcsb pdb:2BWE|rcsb pdb:2BWF|rcsb pdb:3M63|rcsb pdb:4UN2|reactome:R-SCE-8856825|mint:MINT-612583(identity)	-	function:Protein modifier which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Attachment to proteins as a Lys-48-linked polymer usually leads to their degradation by proteasome. Attachment to proteins as a monomer or as an alternatively linked polymer does not lead to proteasomal degradation and may be required for numerous functions, including maintenance of chromatin structure, regulation of gene expression, stress response, ribosome biogenesis and DNA repair|comment:mint|comment:"Stoichiometry: 1.0"	crc64:3F8691BB95E46569|comment:"Stoichiometry: 1.0"	comment:Dsk2 binds to polyubiquitin chains but not to monoubiquitin.|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/09/08	2014/10/16	rogid:+GNv/Jc7C11q8cgu2qZ6YkcsIeI559292	rogid:1hHbfo970BiDc/ZuAO8Jc6V9vEI559292	intact-crc:14B176D522435872|rigid:YlNIedx16tlOxK6OPSpYFODQ3Zo	false	mutation decreasing interaction:48-48(MINT-612592)	tag:?-?(MINT-612586)|binding-associated region:328-373(MINT-612584)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48510	uniprotkb:P33299	intact:EBI-6174|uniprotkb:D6W0A3|ensemblfungi:YMR276W	intact:EBI-13910|uniprotkb:D6VX51|ensemblfungi:YKL145W	psi-mi:dsk2_yeast(display_long)|uniprotkb:DSK2(gene name)|psi-mi:DSK2(display_short)|uniprotkb:SHE4(gene name synonym)|uniprotkb:YMR276W(locus name)|uniprotkb:YM8021.02(orf name)	psi-mi:prs7_yeast(display_long)|uniprotkb:YKL145W(locus name)|uniprotkb:RPT1(gene name)|psi-mi:RPT1(display_short)|uniprotkb:CIM5(gene name synonym)|uniprotkb:YTA3(gene name synonym)|uniprotkb:Protein CIM5(gene name synonym)|uniprotkb:Tat-binding homolog 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Funakoshi et al. (2002)	pubmed:11805328|mint:MINT-5215046	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8083496|mint:MINT-50254	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014003.1|sgd:S000004889|dip:DIP-4398N|mint:P48510|ensemblfungi:YMR276W(gene)|ensemblfungi:YMR276W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019954|interpro:IPR029071|rcsb pdb:1WR1|rcsb pdb:2BWB|rcsb pdb:2BWE|rcsb pdb:2BWF|rcsb pdb:3M63|rcsb pdb:4UN2|reactome:R-SCE-8856825|mint:MINT-612522(identity)	refseq:NP_012777.1|sgd:S000001628|ensemblfungi:YKL145W(gene)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|ensemblfungi:YKL145W_mRNA(transcript)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|go:"GO:0005634"(nucleus)|rcsb pdb:3VLF|rcsb pdb:4A3V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4JPO|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|rcsb pdb:5A5B|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:5MP9|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:6EF3|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33299|dip:DIP-2883N|mint:MINT-612530(identity)	-	crc64:3F8691BB95E46569|comment:"Stoichiometry: 1.0"	crc64:8454BBC9D549EC5C|comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/09/08	2014/10/16	rogid:1hHbfo970BiDc/ZuAO8Jc6V9vEI559292	rogid:8XXo53yZ1KevHObtYWABeFr0hWo559292	intact-crc:AAB55097690D4428|rigid:ILHHBsqSIMZazZX6lYaxjd8dthE	false	binding-associated region:1-72(MINT-612523)|tag:?-?(MINT-612525)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0CG63	uniprotkb:P48510	intact:EBI-7000452|ensemblfungi:YLL039C|intact:MINT-545233|uniprotkb:D6VXW7|uniprotkb:P61864|uniprotkb:Q6LA96|uniprotkb:P04838	intact:EBI-6174|uniprotkb:D6W0A3|ensemblfungi:YMR276W	psi-mi:ubi4p_yeast(display_long)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name)	psi-mi:dsk2_yeast(display_long)|uniprotkb:DSK2(gene name)|psi-mi:DSK2(display_short)|uniprotkb:SHE4(gene name synonym)|uniprotkb:YMR276W(locus name)|uniprotkb:YM8021.02(orf name)	psi-mi:"MI:0018"(two hybrid)	Funakoshi et al. (2002)	pubmed:11805328|mint:MINT-5215046	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8083521|mint:MINT-50250	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLL039C(gene)|ensemblfungi:YLL039C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:2KDI|rcsb pdb:2L00|rcsb pdb:3CMM|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3OLM|rcsb pdb:4HCN|rcsb pdb:4NNJ|rcsb pdb:4Q5E|rcsb pdb:4Q5H|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-156827|reactome:R-SCE-174113|reactome:R-SCE-1799339|reactome:R-SCE-532668|reactome:R-SCE-5358346|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5687128|reactome:R-SCE-5689603|reactome:R-SCE-5689877|reactome:R-SCE-5689880|reactome:R-SCE-5689901|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6791226|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-72649|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72706|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-8948747|reactome:R-SCE-8948751|reactome:R-SCE-901032|reactome:R-SCE-9020702|reactome:R-SCE-9033241|reactome:R-SCE-917729|reactome:R-SCE-9646399|reactome:R-SCE-975956|reactome:R-SCE-975957|reactome:R-SCE-983168|interpro:IPR000626(Ubiquitin)|sgd:S000003962|interpro:IPR019956|interpro:IPR019954|refseq:NP_013061.1|interpro:IPR029071|mint:P0CG63|mint:MINT-612561(identity)	refseq:NP_014003.1|sgd:S000004889|dip:DIP-4398N|mint:P48510|ensemblfungi:YMR276W(gene)|ensemblfungi:YMR276W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019954|interpro:IPR029071|rcsb pdb:1WR1|rcsb pdb:2BWB|rcsb pdb:2BWE|rcsb pdb:2BWF|rcsb pdb:3M63|rcsb pdb:4UN2|reactome:R-SCE-8856825|mint:MINT-612553(identity)	-	function:Protein modifier which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Attachment to proteins as a Lys-48-linked polymer usually leads to their degradation by proteasome. Attachment to proteins as a monomer or as an alternatively linked polymer does not lead to proteasomal degradation and may be required for numerous functions, including maintenance of chromatin structure, regulation of gene expression, stress response, ribosome biogenesis and DNA repair|comment:mint|comment:"Stoichiometry: 1.0"	crc64:3F8691BB95E46569|comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2004/09/08	2014/10/16	rogid:+GNv/Jc7C11q8cgu2qZ6YkcsIeI559292	rogid:1hHbfo970BiDc/ZuAO8Jc6V9vEI559292	intact-crc:82EC1413EE0E196E|rigid:YlNIedx16tlOxK6OPSpYFODQ3Zo	false	tag:?-?(MINT-612562)	binding-associated region:?-?(MINT-612554)|tag:?-?(MINT-612556)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)