#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P54733	uniprotkb:Q9VZF4	intact:EBI-203549|intact:EBI-1628120|uniprotkb:Q24479|uniprotkb:Q95RP5|uniprotkb:Q9V3B3|uniprotkb:Q9V456|ensemblmetazoa:FBpp0080331|ensemblmetazoa:FBpp0080332|ensemblmetazoa:FBpp0080333|ensemblmetazoa:FBpp0080334	intact:EBI-138334|intact:EBI-1628008|uniprotkb:A4V1G6|ensemblmetazoa:FBpp0073101|ensemblmetazoa:FBpp0073102|ensemblmetazoa:FBpp0073103	psi-mi:ccne_drome(display_long)|uniprotkb:CycE(gene name)|psi-mi:CycE(display_short)|uniprotkb:CG3938(orf name)	psi-mi:fbxw7_drome(display_long)|uniprotkb:ago(gene name)|psi-mi:ago(display_short)|uniprotkb:CG15010(orf name)|uniprotkb:F-box and WD-40 domain-containing protein 7(gene name synonym)|uniprotkb:Protein archipelago(gene name synonym)	psi-mi:"MI:0096"(pull down)	Moberg et al. (2001)	pubmed:11565033	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-490515	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476959.1|refseq:NP_476960.1|refseq:NP_723924.1|refseq:NP_723925.1|refseq:NP_723926.1|flybase:FBgn0010382|dip:DIP-18331N|ensemblmetazoa:FBgn0010382(gene)|ensemblmetazoa:FBtr0080773(transcript)|ensemblmetazoa:FBtr0080774(transcript)|ensemblmetazoa:FBtr0080775(transcript)|ensemblmetazoa:FBtr0080776(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007277"(pole cell development)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035736"(cell proliferation involved in compound eye morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048665"(neuron fate specification)|go:"GO:0090210"(regulation of establishment of blood-brain barrier)|go:"GO:0097134"(cyclin E1-CDK2 complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P54733|reactome:R-DME-1538133|reactome:R-DME-187577|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-9706019	go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|go:"GO:1900038"(negative regulation of cellular response to hypoxia)|ensemblmetazoa:FBtr0073246(transcript)|ensemblmetazoa:FBtr0073247(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007419"(ventral cord development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030332"(cyclin binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0045571"(negative regulation of imaginal disc growth)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060438"(trachea development)|go:"GO:0071456"(cellular response to hypoxia)|ensemblmetazoa:FBgn0041171(gene)|ensemblmetazoa:FBtr0073245(transcript)|refseq:NP_523922.1|refseq:NP_728964.1|refseq:NP_728965.1|flybase:FBgn0041171|dip:DIP-32477N	-	-	-	dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/11/10	2014/10/16	rogid:AwK/vwBDPgICbmeNxOxrcsj5kiQ7227	rogid:FVPUJUP1NZ/drDu6C4uA3VDNv307227	intact-crc:2C500F35050C9FFA|rigid:btrJj3pkDNgfIyYdPotRoF96ppg	false	myc tag:n-n	binding-associated region:667-1326(IPR001680)|glutathione s tranferase tag:n-n|mutation decreasing interaction:1131-1131	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)