#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P00451 uniprotkb:P01619 intact:EBI-1046394|ensembl:ENSP00000353393|uniprotkb:Q5HY69|uniprotkb:Q14286 intact:EBI-1221053|uniprotkb:P01622|uniprotkb:P01621|uniprotkb:P01623|uniprotkb:P04206|uniprotkb:P06311|uniprotkb:P18135|uniprotkb:P18136|intact:EBI-6677691|intact:EBI-3048564|uniprotkb:A0A0B4J1Z6|uniprotkb:P01620|ensembl:ENSP00000418649|ensembl:ENSP00000487628 psi-mi:fa8_human(display_long)|uniprotkb:Procoagulant component(gene name synonym)|uniprotkb:Antihemophilic factor(gene name synonym)|uniprotkb:F8(gene name)|psi-mi:F8(display_short)|uniprotkb:F8C(gene name synonym) psi-mi:kv320_human(display_long)|uniprotkb:IGKV3-20(gene name)|psi-mi:IGKV3-20(display_short)|uniprotkb:Ig kappa chain V-III region B6(gene name synonym)|uniprotkb:Ig kappa chain V-III region GOL(gene name synonym)|uniprotkb:Ig kappa chain V-III region HAH(gene name synonym)|uniprotkb:Ig kappa chain V-III region HIC(gene name synonym)|uniprotkb:Ig kappa chain V-III region IARC/BL41(gene name synonym)|uniprotkb:Ig kappa chain V-III region NG9(gene name synonym)|uniprotkb:Ig kappa chain V-III region SIE(gene name synonym)|uniprotkb:Ig kappa chain V-III region Ti(gene name synonym)|uniprotkb:Ig kappa chain V-III region WOL(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Spiegel et al. (2001) pubmed:11418455|mint:MINT-5214182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7878814|mint:MINT-24963 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000185010(gene)|ensembl:ENST00000360256(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006953"(acute-phase response)|go:"GO:0007596"(blood coagulation)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR001117(Multicopper oxidase, type 1)|interpro:IPR008972(Cupredoxin)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011706(Multicopper oxidase, type 2)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR024715|interpro:IPR033138|rcsb pdb:1CFG|rcsb pdb:1D7P|rcsb pdb:1FAC|rcsb pdb:1IQD|rcsb pdb:2R7E|rcsb pdb:3CDZ|rcsb pdb:3HNB|rcsb pdb:3HNY|rcsb pdb:3HOB|rcsb pdb:3J2Q|rcsb pdb:3J2S|go:"GO:0007597"(blood coagulation, intrinsic pathway)|rcsb pdb:4BDV|rcsb pdb:4KI5|rcsb pdb:4PT6|rcsb pdb:4XZU|go:"GO:0016491"(oxidoreductase activity)|rcsb pdb:5K8D|rcsb pdb:6MF2|rcsb pdb:7KWO|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-163841|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-9672383|reactome:R-HSA-9672387|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9672395|reactome:R-HSA-9672396|reactome:R-HSA-9672397|reactome:R-HSA-9673202|reactome:R-HSA-9674519|refseq:NP_000123.1|refseq:NP_063916.1|dip:DIP-29774N|mint:MINT-579841(identity) ensembl:ENSG00000239951(gene)|ensembl:ENSG00000282402(gene)|ensembl:ENST00000492167(transcript)|ensembl:ENST00000632822(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003094"(glomerular filtration)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071748"(monomeric IgA immunoglobulin complex)|go:"GO:0071751"(secretory IgA immunoglobulin complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1DH5|rcsb pdb:4LRN|rcsb pdb:4M62|rcsb pdb:4M8Q|rcsb pdb:4OB5|rcsb pdb:4ODX|reactome:R-HSA-166663|reactome:R-HSA-173623|go:"GO:0071756"(pentameric IgM immunoglobulin complex)|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695|mint:MINT-579834(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:In the xray complex 1iqd, P18135 is chain A and P00451 is chain C Resolution 2.000|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/02/12 2016/11/30 rogid:yKYkVF2eCO1fS/Dp3/k1qcP5YM49606 rogid:A3tiGZV68B7iHX4VcexKiL7V6bE9606 intact-crc:E07FCA5030494698|rigid:d6vIMDkIhz9md7GbZo2EhcablJk false tag:?-?(MINT-579842) tag:?-?(MINT-579835) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)