#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q05080 uniprotkb:P37370 intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym) psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:"MI:0018"(two hybrid) Naqvi et al. (2001) pubmed:11260524|mint:MINT-5213747|doi:10.1034/j.1600-0854.2001.020305 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7799143|mint:MINT-50127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828|mint:MINT-470396(identity) refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370|mint:MINT-470387(identity) - crc64:AE4A76C2F4043021|comment:"Stoichiometry: 1.0" crc64:24C7522D5B1CA1C8|comment:"Stoichiometry: 1.0" comment:domino|comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2004/07/26 2014/10/16 rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 intact-crc:75FD86032487A262|rigid:HYFns3neegvPhoNSeECsYbHkEmI false binding-associated region:501-669(MINT-470397)|tag:?-?(MINT-470400) tag:?-?(MINT-470391)|binding-associated region:2-269(MINT-470388) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P37370 uniprotkb:Q05080 intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Naqvi et al. (2001) pubmed:11260524|mint:MINT-5213747|doi:10.1034/j.1600-0854.2001.020305 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7799208|mint:MINT-50128 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370|mint:MINT-470417(identity) refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828|mint:MINT-470409(identity) - crc64:24C7522D5B1CA1C8|comment:"Stoichiometry: 1.0" crc64:AE4A76C2F4043021|comment:"Stoichiometry: 1.0" comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2004/07/26 2014/10/16 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292 intact-crc:A47A7F6EE55F9492|rigid:HYFns3neegvPhoNSeECsYbHkEmI false tag:?-?(MINT-470418) binding-associated region:501-669(MINT-470410)|tag:?-?(MINT-470412) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P37370 uniprotkb:Q05080 intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym) psi-mi:"MI:0428"(imaging technique) Naqvi et al. (2001) pubmed:11260524|mint:MINT-5213747|doi:10.1034/j.1600-0854.2001.020305 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7799253|mint:MINT-50129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370|mint:MINT-470432(identity) refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828|mint:MINT-470427(identity) - crc64:24C7522D5B1CA1C8|comment:"Stoichiometry: 1.0" crc64:AE4A76C2F4043021|comment:"Stoichiometry: 1.0" comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2004/07/26 2014/10/16 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292 intact-crc:944203928190CE25|rigid:HYFns3neegvPhoNSeECsYbHkEmI false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q05080 uniprotkb:Q05080 intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym) psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Naqvi et al. (2001) pubmed:11260524|mint:MINT-5213747|doi:10.1034/j.1600-0854.2001.020305 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7799270|mint:MINT-7721230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828|mint:MINT-7721242(identity)|uniprotkb:Q05080(original identifier) refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828|mint:MINT-7721231(identity)|uniprotkb:Q05080(original identifier) - crc64:AE4A76C2F4043021 crc64:AE4A76C2F4043021 figure legend:F6B|comment:homomint|comment:domino|comment:mint|figure legend:F6A taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2004/07/26 2014/10/16 rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292 rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292 intact-crc:AC8AB40E94B67298|rigid:HYFns3neegvPhoNSeECsYbHkEmI false binding-associated region:602-666(MINT-7721245) binding-associated region:602-666(MINT-7721234) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05080 uniprotkb:P37370 intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym) psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:"MI:0018"(two hybrid) Naqvi et al. (2001) pubmed:11260524|mint:MINT-5213747|doi:10.1034/j.1600-0854.2001.020305 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7799270|mint:MINT-7721230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828|mint:MINT-7721242(identity)|uniprotkb:Q05080(original identifier) refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370|mint:MINT-7721237(identity)|uniprotkb:P37370(original identifier) - crc64:AE4A76C2F4043021 crc64:24C7522D5B1CA1C8 figure legend:F6B|comment:homomint|comment:domino|comment:mint|figure legend:F6A taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2004/07/26 2014/10/16 rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 intact-crc:AC8AB40E94B67298|rigid:HYFns3neegvPhoNSeECsYbHkEmI false binding-associated region:602-666(MINT-7721245) binding-associated region:1-267(MINT-7721240) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05080 uniprotkb:P37370 intact:EBI-5412|uniprotkb:D6VZK6|ensemblfungi:YMR032W intact:EBI-20502|uniprotkb:Q06133|uniprotkb:D6VYX7|ensemblfungi:YLR337C psi-mi:cyk2_yeast(display_long)|uniprotkb:HOF1(gene name)|psi-mi:HOF1(display_short)|uniprotkb:CYK2(gene name synonym)|uniprotkb:YMR032W(locus name)|uniprotkb:YM9973.05(orf name)|uniprotkb:Homolog of CDC15 protein 1(gene name synonym) psi-mi:vrp1_yeast(display_long)|uniprotkb:VRP1(gene name)|psi-mi:VRP1(display_short)|uniprotkb:END5(gene name synonym)|uniprotkb:MDP2(gene name synonym)|uniprotkb:YLR337C(locus name)|uniprotkb:L8300.13(orf name) psi-mi:"MI:0018"(two hybrid) Naqvi et al. (2001) pubmed:11260524|mint:MINT-5213747|doi:10.1034/j.1600-0854.2001.020305 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7799270|mint:MINT-7721230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013746.1|sgd:S000004635|dip:DIP-2729N|mint:Q05080|ensemblfungi:YMR032W(gene)|ensemblfungi:YMR032W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0044697"(HICS complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0090339"(negative regulation of formin-nucleated actin cable assembly)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:0120155"(MIH complex)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:4WPE|reactome:R-SCE-8856828|mint:MINT-7721242(identity)|uniprotkb:Q05080(original identifier) refseq:NP_013441.1|sgd:S000004329|ensemblfungi:YLR337C(gene)|ensemblfungi:YLR337C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003779"(actin binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007121"(bipolar cellular bud site selection)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|dip:DIP-860N|mint:P37370|mint:MINT-7721248(identity)|uniprotkb:P37370(original identifier) - crc64:AE4A76C2F4043021 crc64:24C7522D5B1CA1C8 figure legend:F6B|comment:homomint|comment:domino|comment:mint|figure legend:F6A taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2004/07/26 2014/10/16 rogid:qBPbR9tsmNdnLskxUFCF8vUQ0xI559292 rogid:BhO3SMGOCWaoVFCOzN+g4FSzxoQ559292 intact-crc:AC8AB40E94B67298|rigid:HYFns3neegvPhoNSeECsYbHkEmI false binding-associated region:602-666(MINT-7721245) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)