#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P25604	uniprotkb:P52917	intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C	intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C	psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym)	psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Babst et al. (2000)	pubmed:11208108|mint:MINT-5213557|doi:10.1034/j.1600-0854.2000.010307	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7769688|mint:MINT-50305	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N|mint:MINT-468333(identity)	refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917|mint:MINT-468339(identity)	-	crc64:FEDE3BE79F063BCE|comment:"Stoichiometry: 1.0"	crc64:E65BCDB19C9510DD|comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2004/09/10	2014/10/16	rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292	rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292	intact-crc:830D61BB2549EFFB|rigid:FD5LPXxBOVV89jTONhod9h0vbiQ	true	tag:?-?(MINT-468334)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q9P7F7	uniprotkb:P25604	intact:EBI-7769798|ensemblfungi:"SPAC1142.07c.1:pep"|intact:MINT-468312	intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C	psi-mi:snf7_schpo(display_long)|uniprotkb:snf7(gene name)|psi-mi:snf7(display_short)|uniprotkb:vps32(gene name synonym)|uniprotkb:SPAC1142.07c(orf name)|uniprotkb:Vacuolar protein-sorting-associated protein 32(gene name synonym)	psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Babst et al. (2000)	pubmed:11208108|mint:MINT-5213557|doi:10.1034/j.1600-0854.2000.010307	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7769793|mint:MINT-50307	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SPO-1632852|reactome:R-SPO-917729|ensemblfungi:SPAC1142.07c(gene)|ensemblfungi:SPAC1142.07c.1(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|refseq:NP_594271.1|interpro:IPR005024(Snf7)|reactome:R-SPO-9668328|mint:MINT-468326(identity)	refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N|mint:MINT-468320(identity)	-	function:"Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB)"|comment:mint|comment:"Stoichiometry: 1.0"	crc64:FEDE3BE79F063BCE|comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|comment:mint|negative:true	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2004/09/10	2014/10/16	rogid:vm71xGBSGFui19WZ5oWLutT2KjE284812	rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292	intact-crc:2E16718D9F1F4B25|rigid:mZ4hK8MZIdkgPTF3LEleLbCWYu0	true	-	tag:?-?(MINT-468321)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25604	uniprotkb:P36095	intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C	intact:EBI-26653|uniprotkb:D6VXP5|ensemblfungi:YKL041W	psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym)	psi-mi:vps24_yeast(display_long)|uniprotkb:YKL041W(locus name)|uniprotkb:YKL254(orf name)|uniprotkb:VPS24(gene name)|psi-mi:VPS24(display_short)|uniprotkb:DID3(gene name synonym)|uniprotkb:DOA4-independent degradation protein 3(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS24(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Babst et al. (2000)	pubmed:11208108|mint:MINT-5213557|doi:10.1034/j.1600-0854.2000.010307	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7769729|mint:MINT-50306	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N|mint:MINT-468364(identity)	refseq:NP_012883.1|sgd:S000001524|mint:P36095|dip:DIP-7295N|ensemblfungi:YKL041W(gene)|ensemblfungi:YKL041W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:6ZH3|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|mint:MINT-468370(identity)	-	crc64:FEDE3BE79F063BCE|comment:"Stoichiometry: 1.0"	crc64:6073C1B680D58E98|comment:"Stoichiometry: 1.0"	negative:the interactions are not observed under these experimental conditions|comment:homomint|comment:mint|negative:true	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2004/09/10	2014/10/16	rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292	rogid:mA7XIOAPTcq8iFqDtd5Uk4cdhD0559292	intact-crc:28F3DFCF87B125D0|rigid:SPcYyXHPFHOu/wiiApqLGr9J7vM	true	tag:?-?(MINT-468365)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)