#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0C1Y9 uniprotkb:P22303 intact:EBI-7425928|uniprotkb:P01403|intact:MINT-149065 intact:EBI-1637793|uniprotkb:Q16169|uniprotkb:Q86TM9|uniprotkb:Q9BXP7|uniprotkb:A4D2E2|uniprotkb:Q29S23|uniprotkb:Q2M324|uniprotkb:Q504V3|uniprotkb:Q86YX9|uniprotkb:D6W5X7|uniprotkb:B7ZKZ0|uniprotkb:Q53F46|ensembl:ENSP00000394976|ensembl:ENSP00000414858|ensembl:ENSP00000241069 psi-mi:3se1_denan(display_long)|uniprotkb:Fasciculin-I(gene name synonym)|uniprotkb:Toxin TA1(gene name synonym) psi-mi:aces_human(display_long)|uniprotkb:ACHE(gene name)|psi-mi:ACHE(display_short) psi-mi:"MI:0114"(x-ray crystallography) Kryger et al. (2000) pubmed:11053835|mint:MINT-5213134 taxid:8618(denan)|taxid:8618(Dendroaspis angusticeps) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7425958|mint:MINT-24773 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018354|rcsb pdb:1FAS|go:"GO:0005576"(extracellular region)|go:"GO:0090729"(toxin activity)|mint:MINT-433226(identity) refseq:XP_011514530.1|refseq:XP_011514531.1|refseq:NP_000656.1|refseq:NP_056646.1|ensembl:ENSG00000087085|refseq:XP_006716058.1|refseq:NP_001289550.1|refseq:NP_001289551.1|refseq:NP_001269378.1|dip:DIP-1119N|ensembl:ENSG00000087085(gene)|ensembl:ENST00000241069(transcript)|ensembl:ENST00000412389(transcript)|ensembl:ENST00000428317(transcript)|go:"GO:0001507"(acetylcholine catabolic process in synaptic cleft)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0002076"(osteoblast development)|go:"GO:0003990"(acetylcholinesterase activity)|go:"GO:0004104"(cholinesterase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006581"(acetylcholine catabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007416"(synapse assembly)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032223"(negative regulation of synaptic transmission, cholinergic)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043236"(laminin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000997(Cholinesterase)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR014788(Acetylcholinesterase, tetramerisation)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|rcsb pdb:1B41|rcsb pdb:1F8U|rcsb pdb:1PUV|rcsb pdb:1PUW|rcsb pdb:1VZJ|rcsb pdb:2CLJ|rcsb pdb:2X8B|rcsb pdb:3LII|rcsb pdb:4BDT|rcsb pdb:4EY4|rcsb pdb:4EY5|rcsb pdb:4EY6|rcsb pdb:4EY7|rcsb pdb:4EY8|rcsb pdb:4M0E|rcsb pdb:4M0F|rcsb pdb:4PQE|rcsb pdb:5FOQ|rcsb pdb:5FPQ|rcsb pdb:5HF5|rcsb pdb:5HF6|rcsb pdb:5HF8|rcsb pdb:5HF9|rcsb pdb:5HFA|rcsb pdb:6CQT|rcsb pdb:6CQU|rcsb pdb:6CQV|rcsb pdb:6CQW|rcsb pdb:6CQX|rcsb pdb:6CQY|rcsb pdb:6CQZ|rcsb pdb:6F25|rcsb pdb:6NEA|rcsb pdb:6NTG|rcsb pdb:6NTH|rcsb pdb:6NTK|rcsb pdb:6NTL|rcsb pdb:6NTM|rcsb pdb:6NTN|rcsb pdb:6NTO|rcsb pdb:6O4W|rcsb pdb:6O4X|rcsb pdb:6O50|rcsb pdb:6O52|rcsb pdb:6O5R|rcsb pdb:6O5S|rcsb pdb:6O5V|rcsb pdb:6O66|rcsb pdb:6O69|rcsb pdb:6U34|rcsb pdb:6U37|rcsb pdb:6U3P|rcsb pdb:6WUV|rcsb pdb:6WUY|rcsb pdb:6WUZ|rcsb pdb:6WV1|rcsb pdb:6WVC|rcsb pdb:6WVO|rcsb pdb:6WVP|rcsb pdb:6WVQ|rcsb pdb:6ZWE|reactome:R-HSA-112311|reactome:R-HSA-1483191|reactome:R-HSA-422085|mint:MINT-433219(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:In the xray complex 1b41, P22303 is chain A and P01403 is chain B Resolution 2.760|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/02/12 2014/10/16 rogid:4Y03QoWloLNq/iw+ZwxxbA89NqU8618 rogid:7JpI1FosTcbuldkkW4tg62j1piE9606 intact-crc:D261AD29D6F1B30B|rigid:l1cpOAC4P6QYPWlZRIpnWPvXsq4 false tag:?-?(MINT-433227) tag:?-?(MINT-433220) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)