#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O54788 uniprotkb:O54786 intact:EBI-7365197|intact:MINT-142143|ensembl:ENSMUSP00000030893 intact:EBI-1634519|uniprotkb:O54787|uniprotkb:Q8BQC7|uniprotkb:B2KFX0|ensembl:ENSMUSP00000030816 psi-mi:dffb_mouse(display_long)|uniprotkb:Dffb(gene name)|psi-mi:Dffb(display_short)|uniprotkb:Cad(gene name synonym)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym) psi-mi:dffa_mouse(display_long)|uniprotkb:Dffa(gene name)|psi-mi:Dffa(display_short)|uniprotkb:Icad(gene name synonym)|uniprotkb:DNA fragmentation factor 45 kDa subunit(gene name synonym)|uniprotkb:Inhibitor of CAD(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Otomo et al. (2000) pubmed:10932250|mint:MINT-5212876 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7365225|mint:MINT-24958 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031885.3|ensembl:ENSMUSG00000029027(gene)|ensembl:ENSMUST00000030893(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|mint:O54788|rcsb pdb:1C9F|rcsb pdb:1F2R|rcsb pdb:1V0D|reactome:R-MMU-140342|mint:MINT-429404(identity) refseq:NP_001020467.1|ensembl:ENSMUSG00000028974(gene)|ensembl:ENSMUST00000030816(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032076"(negative regulation of deoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015121(DNA Fragmentation factor 45kDa, C terminal)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|interpro:IPR027296|rcsb pdb:1F2R|reactome:R-MMU-140342|mint:MINT-429411(identity) - comment:mint|function:Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology|comment:homomint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:In the xray complex 1f2r, O54788 is chain C and O54786 is chain I Resolution|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/02/12 2014/10/16 rogid:6BiQzdEqkkJvzK4tj/xdBvpkWKY10090 rogid:MVg3+6pxmmcKBjFz1apoG3Di0Ig10090 intact-crc:F5726218F53BB77E|rigid:88YVovLIn19pXwYxS3t6DpLSqHw false tag:?-?(MINT-429405) tag:?-?(MINT-429412) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)