#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P07830	uniprotkb:P06396	intact:EBI-7195234|ensemblprotists:EAL62543|ensemblprotists:EAL62666|ensemblprotists:EAL62918|ensemblprotists:EAL62963|ensemblprotists:EAL67074|ensemblprotists:EAL69957|ensemblprotists:EAL69959|ensemblprotists:EAL69960|ensemblprotists:EAL69961|ensemblprotists:EAL70035|ensemblprotists:EAL70173|ensemblprotists:EAL70192|ensemblprotists:EAL70193|ensemblprotists:EAL70256|ensemblprotists:EAL71184|ensemblprotists:EAL71276|ensemblprotists:EAL71967|uniprotkb:P02577|uniprotkb:Q23875|uniprotkb:Q23856|uniprotkb:Q23880|intact:MINT-121645|uniprotkb:P07827|uniprotkb:Q7KWV6|uniprotkb:Q23877|uniprotkb:Q94466|uniprotkb:Q54H30|uniprotkb:Q23879	intact:EBI-351506|uniprotkb:Q8WVV7|ensembl:ENSP00000362924|uniprotkb:Q5T0I2|uniprotkb:A8MUD1|uniprotkb:B7Z373|uniprotkb:A2A418|uniprotkb:A8MYN7|uniprotkb:B7Z5V1|uniprotkb:F5H1A8	psi-mi:act1_dicdi(display_long)|uniprotkb:act1(gene name)|psi-mi:act1(display_short)|uniprotkb:act2(gene name)|psi-mi:act2(display_short)|uniprotkb:act4(gene name)|psi-mi:act4(display_short)|uniprotkb:act5(gene name)|psi-mi:act5(display_short)|uniprotkb:act6(gene name)|psi-mi:act6(display_short)|uniprotkb:act7(gene name)|psi-mi:act7(display_short)|uniprotkb:act8(gene name)|psi-mi:act8(display_short)|uniprotkb:act9(gene name)|psi-mi:act9(display_short)|uniprotkb:act11(gene name)|psi-mi:act11(display_short)|uniprotkb:Actin A1(gene name synonym)|uniprotkb:Actin III(gene name synonym)|uniprotkb:Actin-3a(gene name synonym)|uniprotkb:Actin-16(gene name synonym)|uniprotkb:Actin M6(gene name synonym)|uniprotkb:Actin-19(gene name synonym)|uniprotkb:Actin-20(gene name synonym)|uniprotkb:Actin-21(gene name synonym)|uniprotkb:DDB_G0289553(orf name)|uniprotkb:DDB_G0274133(orf name)|uniprotkb:DDB_G0289005(orf name)|uniprotkb:DDB_G0289663(orf name)|uniprotkb:DDB_G0274135(orf name)|uniprotkb:DDB_G0280545(orf name)|uniprotkb:DDB_G0269234(orf name)|uniprotkb:DDB_G0274601(orf name)|uniprotkb:DDB_G0288879(orf name)|uniprotkb:DDB_G0274129(orf name)|uniprotkb:DDB_G0274599(orf name)|uniprotkb:DDB_G0274137(orf name)|uniprotkb:DDB_G0272520(orf name)|uniprotkb:DDB_G0272248(orf name)|uniprotkb:DDB_G0274727(orf name)|uniprotkb:DDB_G0274285(orf name)|uniprotkb:DDB_G0274561(orf name)|uniprotkb:act12(gene name)|psi-mi:act12(display_short)|uniprotkb:act13(gene name)|psi-mi:act13(display_short)|uniprotkb:act14(gene name)|psi-mi:act14(display_short)|uniprotkb:act15(gene name)|psi-mi:act15(display_short)|uniprotkb:act16(gene name)|psi-mi:act16(display_short)|uniprotkb:act19(gene name)|psi-mi:act19(display_short)|uniprotkb:act20(gene name)|psi-mi:act20(display_short)|uniprotkb:act21(gene name)|psi-mi:act21(display_short)|uniprotkb:act1a(gene name synonym)|uniprotkb:act2-1(gene name synonym)|uniprotkb:actA8(gene name synonym)|uniprotkb:actB1(gene name synonym)|uniprotkb:actA1(gene name synonym)|uniprotkb:actM6(gene name synonym)|uniprotkb:Actin-1(gene name synonym)|uniprotkb:Actin-2(gene name synonym)|uniprotkb:Actin-2-sub 1(gene name synonym)|uniprotkb:Actin-4(gene name synonym)|uniprotkb:Actin-5(gene name synonym)|uniprotkb:Actin-6(gene name synonym)|uniprotkb:Actin-7(gene name synonym)|uniprotkb:Actin-8(gene name synonym)|uniprotkb:Actin A8(gene name synonym)|uniprotkb:Actin-IEL1(gene name synonym)|uniprotkb:Actin-9(gene name synonym)|uniprotkb:Actin-11(gene name synonym)|uniprotkb:Actin-12(gene name synonym)|uniprotkb:Actin A12(gene name synonym)|uniprotkb:Actin-13(gene name synonym)|uniprotkb:Actin-14(gene name synonym)|uniprotkb:Actin-15(gene name synonym)	psi-mi:gels_human(display_long)|uniprotkb:GSN(gene name)|psi-mi:GSN(display_short)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)|uniprotkb:AGEL(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Matsuura et al. (2000)	pubmed:10669610|mint:MINT-5212231	taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7195382|mint:MINT-24968	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40989N|ensemblprotists:DDB_G0269234(gene)|ensemblprotists:DDB_G0272248(gene)|ensemblprotists:DDB_G0272520(gene)|ensemblprotists:DDB_G0274129(gene)|ensemblprotists:DDB_G0274133(gene)|ensemblprotists:DDB_G0274135(gene)|ensemblprotists:DDB_G0274285(gene)|ensemblprotists:DDB_G0274561(gene)|ensemblprotists:DDB_G0274599(gene)|ensemblprotists:DDB_G0274601(gene)|ensemblprotists:DDB_G0274727(gene)|ensemblprotists:DDB_G0280545(gene)|ensemblprotists:DDB_G0288879(gene)|ensemblprotists:DDB_G0289005(gene)|ensemblprotists:DDB_G0289553(gene)|ensemblprotists:DDB_G0289663(gene)|ensemblprotists:EAL62543(transcript)|ensemblprotists:EAL62666(transcript)|ensemblprotists:EAL62918(transcript)|ensemblprotists:EAL62963(transcript)|ensemblprotists:EAL67074(transcript)|ensemblprotists:DDB_G0274137(gene)|go:"GO:0031143"(pseudopodium)|go:"GO:0031252"(cell leading edge)|go:"GO:0032009"(early phagosome)|go:"GO:0032010"(phagolysosome)|go:"GO:0042331"(phototaxis)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051591"(response to cAMP)|go:"GO:0060187"(cell pole)|go:"GO:0061836"(intranuclear rod)|go:"GO:0061851"(leading edge of lamellipodium)|go:"GO:0070685"(macropinocytic cup)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1C0F|rcsb pdb:1C0G|rcsb pdb:1DEJ|rcsb pdb:1NLV|rcsb pdb:1NM1|rcsb pdb:1NMD|rcsb pdb:3A5L|rcsb pdb:3A5M|rcsb pdb:3A5N|rcsb pdb:3A5O|rcsb pdb:3CHW|rcsb pdb:3CI5|rcsb pdb:3CIP|reactome:R-DDI-114608|reactome:R-DDI-190873|reactome:R-DDI-196025|reactome:R-DDI-2029482|reactome:R-DDI-5626467|reactome:R-DDI-5663213|reactome:R-DDI-8856828|reactome:R-DDI-9013418|refseq:XP_636088.1|refseq:XP_636169.1|refseq:XP_636425.1|refseq:XP_636507.1|refseq:XP_641146.1|refseq:XP_643986.1|refseq:XP_643988.1|refseq:XP_643989.1|refseq:XP_643990.1|refseq:XP_644132.1|refseq:XP_644146.1|refseq:XP_644157.1|refseq:XP_644244.1|refseq:XP_644246.1|refseq:XP_645099.1|go:"GO:0030864"(cortical actin cytoskeleton)|refseq:XP_645262.1|refseq:XP_646688.1|ensemblprotists:EAL69959(transcript)|ensemblprotists:EAL69960(transcript)|ensemblprotists:EAL69961(transcript)|ensemblprotists:EAL70035(transcript)|ensemblprotists:EAL70173(transcript)|ensemblprotists:EAL70192(transcript)|ensemblprotists:EAL69957(transcript)|ensemblprotists:EAL70193(transcript)|ensemblprotists:EAL70256(transcript)|ensemblprotists:EAL71184(transcript)|ensemblprotists:EAL71276(transcript)|ensemblprotists:EAL71967(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005811"(lipid droplet)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017022"(myosin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|dictybase:DDB_G0289553|dictybase:DDB_G0274599|dictybase:DDB_G0274601|dictybase:DDB_G0274561|dictybase:DDB_G0274285|dictybase:DDB_G0289005|dictybase:DDB_G0274137|dictybase:DDB_G0272520|dictybase:DDB_G0288879|dictybase:DDB_G0269234|dictybase:DDB_G0274129|dictybase:DDB_G0272248|dictybase:DDB_G0289663|dictybase:DDB_G0280545|dictybase:DDB_G0274727|dictybase:DDB_G0274135|dictybase:DDB_G0274133|mint:MINT-383142(identity)	refseq:NP_000168.1|refseq:NP_001121134.1|refseq:NP_001121136.1|refseq:NP_001121137.1|refseq:NP_001121138.1|refseq:NP_001121139.1|refseq:NP_937895.1|refseq:XP_011516888.1|refseq:XP_011516889.1|refseq:XP_011516890.1|refseq:XP_011516891.1|refseq:XP_011516892.1|refseq:XP_011516893.1|refseq:XP_011516894.1|refseq:XP_011516895.1|ensembl:ENSG00000148180(gene)|ensembl:ENST00000373818(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007417"(central nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:P06396|rcsb pdb:1C0F|rcsb pdb:1C0G|rcsb pdb:1D4X|rcsb pdb:1DEJ|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1KCQ|rcsb pdb:1MDU|rcsb pdb:1NLV|rcsb pdb:1NM1|rcsb pdb:1NMD|rcsb pdb:1P8X|rcsb pdb:1SOL|rcsb pdb:1T44|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FH1|rcsb pdb:2FH2|rcsb pdb:2FH3|rcsb pdb:2FH4|rcsb pdb:3A5L|rcsb pdb:3A5M|rcsb pdb:3A5N|rcsb pdb:3A5O|rcsb pdb:3CI5|rcsb pdb:3CIP|rcsb pdb:3CJB|rcsb pdb:3CJC|rcsb pdb:3FFK|rcsb pdb:3FFN|rcsb pdb:3TU5|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4S10|rcsb pdb:4Z94|rcsb pdb:5DD2|rcsb pdb:5FAE|rcsb pdb:5FAF|rcsb pdb:5H3M|rcsb pdb:5H3N|rcsb pdb:5O2Z|rcsb pdb:5UBO|rcsb pdb:5ZZ0|rcsb pdb:6H1F|rcsb pdb:6JCO|rcsb pdb:6JEG|rcsb pdb:6JEH|rcsb pdb:6LJE|rcsb pdb:6LJF|rcsb pdb:6Q9R|rcsb pdb:6Q9Z|rcsb pdb:6QBF|rcsb pdb:1P8Z|rcsb pdb:6QW3|reactome:R-HSA-264870|reactome:R-HSA-6798695|reactome:R-HSA-9662361|reactome:R-HSA-977225|refseq:NP_001244958.1|refseq:NP_001244959.1|refseq:NP_001121135.2|refseq:XP_005252000.1|refseq:XP_005252001.1|refseq:XP_005252002.1|refseq:XP_006717142.1|refseq:XP_016870135.1|refseq:XP_016870136.1|refseq:XP_016870137.1|dip:DIP-2196N|mint:MINT-383149(identity)	-	comment:mint|function:Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:In the xray complex 1c0g, P07830 is chain A and P06396 is chain S Resolution 2.000|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/02/12	2014/10/16	rogid:mbCHNagoPP9uoOul5+WvSEZ2Yq444689	rogid:uACf9A+H6LAOAZSMGYqeDwUL1Mc9606	intact-crc:64A3BD2853B32469|rigid:Nq3YF4G8OL67nM7bfIfrF7Hnyh8	false	tag:?-?(MINT-383143)	tag:?-?(MINT-383150)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)