#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q05116	uniprotkb:P26696	intact:EBI-7185480|uniprotkb:Q5D0B8|intact:MINT-121021	intact:EBI-6957733|uniprotkb:Q5D061|intact:MINT-86973	psi-mi:mp2k1_xenla(display_long)|uniprotkb:map2k1(gene name)|psi-mi:map2k1(display_short)|uniprotkb:ERK activator kinase 1(gene name synonym)|uniprotkb:MAPK/ERK kinase 1(gene name synonym)	psi-mi:mk01_xenla(display_long)|uniprotkb:mapk1(gene name)|psi-mi:mapk1(display_short)|uniprotkb:mpk1(gene name synonym)|uniprotkb:Myelin xP42 protein kinase(gene name synonym)|uniprotkb:Myelin basic protein kinase(gene name synonym)|uniprotkb:M phase MAP kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tanoue et al. (2000)	pubmed:10655591|mint:MINT-5212201	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7185473|mint:MINT-19950	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0004708"(MAP kinase kinase activity)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR011009(Protein kinase-like)|refseq:NP_001080299.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|mint:MINT-382837(identity)	go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_001083548.1|interpro:IPR011009(Protein kinase-like)|mint:MINT-382845(identity)	-	function:Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases|comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|function:"Phosphorylates microtubule-associated protein 2 (MAP2). Myelin basic protein (MBP), and Elk-1; may promote entry in the cell cycle. Activated by M phase promoting factor (MPF)"|comment:"Stoichiometry: 1.0"	figure legend:F2A F2B|comment:mint	taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells)	-	2004/01/16	2014/10/16	rogid:Z+J2sZCNDj0fEL4laczsnsBkKso8355	rogid:pVsO+47tJOR2yAYrvuLVW4sJoDg8355	intact-crc:8AD46E40FC4FBC7F|rigid:Q2Y0ltk8HJir2jgfCTcGGXVoyVo	false	mutation decreasing interaction:2-2,3-3,4-4(MINT-382838)	tag:?-?(MINT-382849)|mutation decreasing interaction:321-321,324-324(MINT-382846)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)