#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Y048 uniprotkb:Q9TW65 intact:EBI-322698|uniprotkb:Q9TZI6|ensemblmetazoa:F47G6.1a.1 intact:EBI-446952|uniprotkb:Q9TYG9|uniprotkb:Q9U3H3|ensemblmetazoa:F15D3.1a.1 psi-mi:dtn1_caeel(display_long)|uniprotkb:F47G6.1(orf name)|uniprotkb:dyb-1(gene name)|psi-mi:dyb-1(display_short) psi-mi:dmd_caeel(display_long)|uniprotkb:F15D3.1(orf name)|uniprotkb:dys-1(gene name)|psi-mi:dys-1(display_short) psi-mi:"MI:0096"(pull down) Gieseler et al. (1999) pubmed:10561496 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-446982 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_490860.1|wormbase:F47G6.1|ensemblmetazoa:F47G6.1a.1(transcript)|ensemblmetazoa:WBGene00001115(gene)|go:"GO:0005277"(acetylcholine transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007529"(establishment of synaptic specificity at neuromuscular junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016014"(dystrobrevin complex)|go:"GO:0032224"(positive regulation of synaptic transmission, cholinergic)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0045202"(synapse)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0099536"(synaptic signaling)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|dip:DIP-25663N interpro:IPR011992(EF-Hand type)|refseq:NP_492946.1|refseq:NP_492947.1|wormbase:F15D3.1a|wormbase:F15D3.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036020|interpro:IPR036872|ensemblmetazoa:F15D3.1a.1(transcript)|ensemblmetazoa:WBGene00001131(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016014"(dystrobrevin complex)|go:"GO:0032224"(positive regulation of synaptic transmission, cholinergic)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0042383"(sarcolemma)|go:"GO:0043056"(forward locomotion)|go:"GO:0045202"(synapse)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0099536"(synaptic signaling)|interpro:IPR043145 - - - comment:The region between AA 3531-3618 within the C-terminal of dys-1 is necessary for interaction with dyb-1. taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/10/01 2014/10/16 rogid:k3D9uxI6JVwMQ4n/v0JtyOyEubg6239 rogid:2VXseSin1V9mLwZ4yFtvmJJq0YQ6239 intact-crc:059B94E7EB1E85DB|rigid:xf1e/hOrGvx07NGb+BYSHo/YtZk false radiolabel:?-? glutathione s tranferase tag:3402-3674|binding-associated region:3531-3618 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9TW65 uniprotkb:Q9Y048 intact:EBI-446952|uniprotkb:Q9TYG9|uniprotkb:Q9U3H3|ensemblmetazoa:F15D3.1a.1 intact:EBI-322698|uniprotkb:Q9TZI6|ensemblmetazoa:F47G6.1a.1 psi-mi:dmd_caeel(display_long)|uniprotkb:F15D3.1(orf name)|uniprotkb:dys-1(gene name)|psi-mi:dys-1(display_short) psi-mi:dtn1_caeel(display_long)|uniprotkb:F47G6.1(orf name)|uniprotkb:dyb-1(gene name)|psi-mi:dyb-1(display_short) psi-mi:"MI:0096"(pull down) Gieseler et al. (1999) pubmed:10561496 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-447075 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011992(EF-Hand type)|refseq:NP_492946.1|refseq:NP_492947.1|wormbase:F15D3.1a|wormbase:F15D3.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036020|interpro:IPR036872|ensemblmetazoa:F15D3.1a.1(transcript)|ensemblmetazoa:WBGene00001131(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016014"(dystrobrevin complex)|go:"GO:0032224"(positive regulation of synaptic transmission, cholinergic)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0042383"(sarcolemma)|go:"GO:0043056"(forward locomotion)|go:"GO:0045202"(synapse)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0099536"(synaptic signaling)|interpro:IPR043145 refseq:NP_490860.1|wormbase:F47G6.1|ensemblmetazoa:F47G6.1a.1(transcript)|ensemblmetazoa:WBGene00001115(gene)|go:"GO:0005277"(acetylcholine transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007529"(establishment of synaptic specificity at neuromuscular junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016014"(dystrobrevin complex)|go:"GO:0032224"(positive regulation of synaptic transmission, cholinergic)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0045202"(synapse)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0099536"(synaptic signaling)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|dip:DIP-25663N pubmed:11895430(see-also) - - comment:"The region between AA 478 to 521 of dyb-1 is necessary for interaction with dys-1. This interaction is confirmed by Y2H assay in PMID: 11895430" taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/10/01 2014/10/16 rogid:2VXseSin1V9mLwZ4yFtvmJJq0YQ6239 rogid:k3D9uxI6JVwMQ4n/v0JtyOyEubg6239 intact-crc:19D10D9B550196B1|rigid:xf1e/hOrGvx07NGb+BYSHo/YtZk false radiolabel:?-? glutathione s tranferase tag:390-543|binding-associated region:478-521 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y048 uniprotkb:Q93646 intact:EBI-322698|uniprotkb:Q9TZI6|ensemblmetazoa:F47G6.1a.1 intact:EBI-447079|uniprotkb:Q9XVP8|ensemblmetazoa:F30A10.8.1|ensemblmetazoa:F30A10.8.2 psi-mi:dtn1_caeel(display_long)|uniprotkb:F47G6.1(orf name)|uniprotkb:dyb-1(gene name)|psi-mi:dyb-1(display_short) psi-mi:snt1_caeel(display_long)|uniprotkb:F30A10.8(orf name)|uniprotkb:stn-1(gene name)|psi-mi:stn-1(display_short) psi-mi:"MI:0096"(pull down) Gieseler et al. (1999) pubmed:10561496 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-447090 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_490860.1|wormbase:F47G6.1|ensemblmetazoa:F47G6.1a.1(transcript)|ensemblmetazoa:WBGene00001115(gene)|go:"GO:0005277"(acetylcholine transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007529"(establishment of synaptic specificity at neuromuscular junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016014"(dystrobrevin complex)|go:"GO:0032224"(positive regulation of synaptic transmission, cholinergic)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0045202"(synapse)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0099536"(synaptic signaling)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|dip:DIP-25663N interpro:IPR041428|refseq:NP_492521.1|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR015482(Syntrophin)|wormbase:F30A10.8|interpro:IPR031072|interpro:IPR036034|ensemblmetazoa:F30A10.8.1(transcript)|ensemblmetazoa:F30A10.8.2(transcript)|ensemblmetazoa:WBGene00006062(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005277"(acetylcholine transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0032413"(negative regulation of ion transmembrane transporter activity)|go:"GO:0040013"(negative regulation of locomotion)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0046662"(regulation of oviposition)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0043059"(regulation of forward locomotion)|go:"GO:0045214"(sarcomere organization) pubmed:14499607(see-also) - - comment:The region between AA 391-450 of dyb-1 is necessary for interaction with stn-1. This interaction is confirmed in the Y2H system as in PMID 14499607. taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/10/01 2014/10/16 rogid:k3D9uxI6JVwMQ4n/v0JtyOyEubg6239 rogid:0ny7uoSFlzoURza7jLthHCeLG986239 intact-crc:926D3E9912D0C6D4|rigid:rmhimHFGA6KYtvHjlInRp0qLbnY false glutathione s tranferase tag:390-543|binding-associated region:391-450 radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9TW65 uniprotkb:Q93646 intact:EBI-446952|uniprotkb:Q9TYG9|uniprotkb:Q9U3H3|ensemblmetazoa:F15D3.1a.1 intact:EBI-447079|uniprotkb:Q9XVP8|ensemblmetazoa:F30A10.8.1|ensemblmetazoa:F30A10.8.2 psi-mi:dmd_caeel(display_long)|uniprotkb:F15D3.1(orf name)|uniprotkb:dys-1(gene name)|psi-mi:dys-1(display_short) psi-mi:snt1_caeel(display_long)|uniprotkb:F30A10.8(orf name)|uniprotkb:stn-1(gene name)|psi-mi:stn-1(display_short) psi-mi:"MI:0096"(pull down) Gieseler et al. (1999) pubmed:10561496 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-447099 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011992(EF-Hand type)|refseq:NP_492946.1|refseq:NP_492947.1|wormbase:F15D3.1a|wormbase:F15D3.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036020|interpro:IPR036872|ensemblmetazoa:F15D3.1a.1(transcript)|ensemblmetazoa:WBGene00001131(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016014"(dystrobrevin complex)|go:"GO:0032224"(positive regulation of synaptic transmission, cholinergic)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0042383"(sarcolemma)|go:"GO:0043056"(forward locomotion)|go:"GO:0045202"(synapse)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0099536"(synaptic signaling)|interpro:IPR043145 interpro:IPR041428|refseq:NP_492521.1|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR015482(Syntrophin)|wormbase:F30A10.8|interpro:IPR031072|interpro:IPR036034|ensemblmetazoa:F30A10.8.1(transcript)|ensemblmetazoa:F30A10.8.2(transcript)|ensemblmetazoa:WBGene00006062(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005277"(acetylcholine transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0032413"(negative regulation of ion transmembrane transporter activity)|go:"GO:0040013"(negative regulation of locomotion)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0046662"(regulation of oviposition)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0043059"(regulation of forward locomotion)|go:"GO:0045214"(sarcomere organization) pubmed:14499607(see-also) - - comment:The regions between AA 3402-3473 and 3531-3674 of dys-1 are necessary for interaction with stn-1.|caution:This interaction was not found using the Y2H method as described in PMID 14499607 taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/10/01 2014/10/16 rogid:2VXseSin1V9mLwZ4yFtvmJJq0YQ6239 rogid:0ny7uoSFlzoURza7jLthHCeLG986239 intact-crc:1CE355B82615D33F|rigid:ae4LrzpGY+jNbIiqzf+umLWQpPk false glutathione s tranferase tag:3402-3674|binding-associated region:3402-3473,3531-3674 radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)