#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9W0G1-2 uniprotkb:Q24218 intact:EBI-11420599|ensemblmetazoa:FBpp0072601 intact:EBI-74727 psi-mi:q9w0g1-2(display_long)|uniprotkb:Ptp61F(gene name)|psi-mi:Ptp61F(display_short)|uniprotkb:dPTP61F(gene name synonym)|uniprotkb:CG9181(orf name)|uniprotkb:DPTP61Fn(isoform synonym)|uniprotkb:Nuclear(isoform synonym) psi-mi:q24218_drome(display_long)|uniprotkb:dock(gene name)|psi-mi:dock(display_short)|uniprotkb:CG3727(orf name) psi-mi:"MI:0018"(two hybrid) Clemens et al. (1996) pubmed:8663600 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-74736 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-74714(isoform-parent)|ensemblmetazoa:FBgn0267487(gene)|ensemblmetazoa:FBtr0072717(transcript) flybase:FBgn0010583|go:"GO:0005158"(insulin receptor binding)|go:"GO:0007411"(axon guidance)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR036028|interpro:IPR036860 - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2003/11/07 2015/11/16 rogid:r1KdP/XnCyI/+bIKJPrl+RYiTX87227 rogid:1/0GiSNvZrkPK4ZFhlLHLZZ8DmE7227 intact-crc:C08102C2B14E61A9|rigid:vH8XvnHjrzWlBkvn1SpO12zMP5o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9W0G1 uniprotkb:Q24218 intact:EBI-74714|uniprotkb:Q27932|uniprotkb:Q8SZY3|uniprotkb:Q9W0G2|ensemblmetazoa:FBpp0072602 intact:EBI-74727 psi-mi:ptp61_drome(display_long)|uniprotkb:Ptp61F(gene name)|psi-mi:Ptp61F(display_short)|uniprotkb:CG9181(orf name)|uniprotkb:dPTP61F(gene name synonym) psi-mi:q24218_drome(display_long)|uniprotkb:dock(gene name)|psi-mi:dock(display_short)|uniprotkb:CG3727(orf name) psi-mi:"MI:0018"(two hybrid) Clemens et al. (1996) pubmed:8663600 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-74739 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476687.1|refseq:NP_476688.1|refseq:NP_728600.1|flybase:FBgn0267487|ensemblmetazoa:FBgn0267487(gene)|ensemblmetazoa:FBtr0072718(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005829"(cytosol)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007377"(germ-band extension)|go:"GO:0007411"(axon guidance)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|reactome:R-DME-210688|reactome:R-DME-210693|reactome:R-DME-877312 flybase:FBgn0010583|go:"GO:0005158"(insulin receptor binding)|go:"GO:0007411"(axon guidance)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR036028|interpro:IPR036860 - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2003/11/07 2014/10/16 rogid:3sl9CY+Qpy7O8+wsxvlhLQ1g4po7227 rogid:1/0GiSNvZrkPK4ZFhlLHLZZ8DmE7227 intact-crc:31FFC9D8C8C6EA95|rigid:lnJ6oKP7xbTA032Ql59vzIeA2Qc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q24218 uniprotkb:Q9W0G1 intact:EBI-74727 intact:EBI-74714|uniprotkb:Q27932|uniprotkb:Q8SZY3|uniprotkb:Q9W0G2|ensemblmetazoa:FBpp0072602 psi-mi:q24218_drome(display_long)|uniprotkb:dock(gene name)|psi-mi:dock(display_short)|uniprotkb:CG3727(orf name) psi-mi:ptp61_drome(display_long)|uniprotkb:Ptp61F(gene name)|psi-mi:Ptp61F(display_short)|uniprotkb:CG9181(orf name)|uniprotkb:dPTP61F(gene name synonym) psi-mi:"MI:0096"(pull down) Clemens et al. (1996) pubmed:8663600 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-74745 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0010583|go:"GO:0005158"(insulin receptor binding)|go:"GO:0007411"(axon guidance)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR036028|interpro:IPR036860 refseq:NP_476687.1|refseq:NP_476688.1|refseq:NP_728600.1|flybase:FBgn0267487|ensemblmetazoa:FBgn0267487(gene)|ensemblmetazoa:FBtr0072718(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005829"(cytosol)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007377"(germ-band extension)|go:"GO:0007411"(axon guidance)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|reactome:R-DME-210688|reactome:R-DME-210693|reactome:R-DME-877312 - - - comment:DOCK is GST tagged. taxid:-1(in vitro)|taxid:-1(In vitro) - 2003/11/07 2014/10/16 rogid:1/0GiSNvZrkPK4ZFhlLHLZZ8DmE7227 rogid:3sl9CY+Qpy7O8+wsxvlhLQ1g4po7227 intact-crc:3F46F87AD3D97756|rigid:lnJ6oKP7xbTA032Ql59vzIeA2Qc false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q24218 uniprotkb:Q9W0G1 intact:EBI-74727 intact:EBI-74714|uniprotkb:Q27932|uniprotkb:Q8SZY3|uniprotkb:Q9W0G2|ensemblmetazoa:FBpp0072602 psi-mi:q24218_drome(display_long)|uniprotkb:dock(gene name)|psi-mi:dock(display_short)|uniprotkb:CG3727(orf name) psi-mi:ptp61_drome(display_long)|uniprotkb:Ptp61F(gene name)|psi-mi:Ptp61F(display_short)|uniprotkb:CG9181(orf name)|uniprotkb:dPTP61F(gene name synonym) psi-mi:"MI:0096"(pull down) Clemens et al. (1996) pubmed:8663600 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-74785 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0010583|go:"GO:0005158"(insulin receptor binding)|go:"GO:0007411"(axon guidance)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR036028|interpro:IPR036860 refseq:NP_476687.1|refseq:NP_476688.1|refseq:NP_728600.1|flybase:FBgn0267487|ensemblmetazoa:FBgn0267487(gene)|ensemblmetazoa:FBtr0072718(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005829"(cytosol)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007377"(germ-band extension)|go:"GO:0007411"(axon guidance)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|reactome:R-DME-210688|reactome:R-DME-210693|reactome:R-DME-877312 - - - comment:"DOCK is expressed as a GST fusion protein. C terminal half of PTP61F (AA 298-535) used in the expt." taxid:-1(in vitro)|taxid:-1(In vitro) - 2003/11/07 2014/10/16 rogid:1/0GiSNvZrkPK4ZFhlLHLZZ8DmE7227 rogid:3sl9CY+Qpy7O8+wsxvlhLQ1g4po7227 intact-crc:C5BD4CEF46520F6E|rigid:lnJ6oKP7xbTA032Ql59vzIeA2Qc false glutathione s tranferase tag:?-? binding-associated region:298-535 - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9W0G1 uniprotkb:Q24218 intact:EBI-74714|uniprotkb:Q27932|uniprotkb:Q8SZY3|uniprotkb:Q9W0G2|ensemblmetazoa:FBpp0072602 intact:EBI-74727 psi-mi:ptp61_drome(display_long)|uniprotkb:Ptp61F(gene name)|psi-mi:Ptp61F(display_short)|uniprotkb:CG9181(orf name)|uniprotkb:dPTP61F(gene name synonym) psi-mi:q24218_drome(display_long)|uniprotkb:dock(gene name)|psi-mi:dock(display_short)|uniprotkb:CG3727(orf name) psi-mi:"MI:0019"(coimmunoprecipitation) Clemens et al. (1996) pubmed:8663600 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-74754 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476687.1|refseq:NP_476688.1|refseq:NP_728600.1|flybase:FBgn0267487|ensemblmetazoa:FBgn0267487(gene)|ensemblmetazoa:FBtr0072718(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005829"(cytosol)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007377"(germ-band extension)|go:"GO:0007411"(axon guidance)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|reactome:R-DME-210688|reactome:R-DME-210693|reactome:R-DME-877312 flybase:FBgn0010583|go:"GO:0005158"(insulin receptor binding)|go:"GO:0007411"(axon guidance)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR036028|interpro:IPR036860 - - - - taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2003/11/07 2014/10/16 rogid:3sl9CY+Qpy7O8+wsxvlhLQ1g4po7227 rogid:1/0GiSNvZrkPK4ZFhlLHLZZ8DmE7227 intact-crc:CE28876B22B9ABC1|rigid:lnJ6oKP7xbTA032Ql59vzIeA2Qc false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q24218 uniprotkb:Q9W0G1 intact:EBI-74727 intact:EBI-74714|uniprotkb:Q27932|uniprotkb:Q8SZY3|uniprotkb:Q9W0G2|ensemblmetazoa:FBpp0072602 psi-mi:q24218_drome(display_long)|uniprotkb:dock(gene name)|psi-mi:dock(display_short)|uniprotkb:CG3727(orf name) psi-mi:ptp61_drome(display_long)|uniprotkb:Ptp61F(gene name)|psi-mi:Ptp61F(display_short)|uniprotkb:CG9181(orf name)|uniprotkb:dPTP61F(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Clemens et al. (1996) pubmed:8663600 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-74757 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0010583|go:"GO:0005158"(insulin receptor binding)|go:"GO:0007411"(axon guidance)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR036028|interpro:IPR036860 refseq:NP_476687.1|refseq:NP_476688.1|refseq:NP_728600.1|flybase:FBgn0267487|ensemblmetazoa:FBgn0267487(gene)|ensemblmetazoa:FBtr0072718(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005829"(cytosol)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007377"(germ-band extension)|go:"GO:0007411"(axon guidance)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|reactome:R-DME-210688|reactome:R-DME-210693|reactome:R-DME-877312 - - - - taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2003/11/07 2014/10/16 rogid:1/0GiSNvZrkPK4ZFhlLHLZZ8DmE7227 rogid:3sl9CY+Qpy7O8+wsxvlhLQ1g4po7227 intact-crc:5533BDCC5D8AE67F|rigid:lnJ6oKP7xbTA032Ql59vzIeA2Qc false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot)