#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P33724	uniprotkb:P33724	intact:EBI-79998|ensembl:ENSCAFP00000005060|ensembl:ENSCAFP00030012265|ensembl:ENSCAFP00040026553|uniprotkb:A0M8U8	intact:EBI-79998|ensembl:ENSCAFP00000005060|ensembl:ENSCAFP00030012265|ensembl:ENSCAFP00040026553|uniprotkb:A0M8U8	psi-mi:cav1_canlf(display_long)|uniprotkb:CAV1(gene name)|psi-mi:CAV1(display_short)|uniprotkb:CAV(gene name synonym)|uniprotkb:Vesicular integral-membrane protein VIP21(gene name synonym)	psi-mi:cav1_canlf(display_long)|uniprotkb:CAV1(gene name)|psi-mi:CAV1(display_short)|uniprotkb:CAV(gene name synonym)|uniprotkb:Vesicular integral-membrane protein VIP21(gene name synonym)	psi-mi:"MI:0096"(pull down)	Sargiacomo et al. (1995)	pubmed:7568142	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-80007	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSCAFG00000003404(gene)|ensembl:ENSCAFG00030007606(gene)|ensembl:ENSCAFG00040016536(gene)|ensembl:ENSCAFT00000005462(transcript)|ensembl:ENSCAFT00030014054(transcript)|ensembl:ENSCAFT00040030547(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002931"(response to ischemia)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044860"(protein localization to plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060056"(mammary gland involution)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0042310"(vasoconstriction)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)|go:"GO:0005938"(cell cortex)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007595"(lactation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0015031"(protein transport)|go:"GO:0016050"(vesicle organization)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0003057"(regulation of the force of heart contraction by chemical signal)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032570"(response to progesterone)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033484"(nitric oxide homeostasis)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0038016"(insulin receptor internalization)|go:"GO:0070320"(inward rectifier potassium channel inhibitor activity)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0070836"(caveola assembly)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:2000286"(receptor internalization involved in canonical Wnt signaling pathway)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|go:"GO:1900085"(negative regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001612(Caveolin)|interpro:IPR015504(Caveolin-1)|interpro:IPR018361|reactome:R-CFA-210991|reactome:R-CFA-4641262|reactome:R-CFA-8980692|reactome:R-CFA-9009391|reactome:R-CFA-9013026|reactome:R-CFA-9013106|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903609"(negative regulation of inward rectifier potassium channel activity)|reactome:R-CFA-9013148|reactome:R-CFA-9013149|reactome:R-CFA-9013404|reactome:R-CFA-9013405|reactome:R-CFA-9013407|reactome:R-CFA-9013408|reactome:R-CFA-9035034|reactome:R-CFA-9696264|reactome:R-CFA-9696270|reactome:R-CFA-9696273|refseq:XP_005628404.1|refseq:NP_001003296.1|refseq:XP_013974350.1	ensembl:ENSCAFG00000003404(gene)|ensembl:ENSCAFG00030007606(gene)|ensembl:ENSCAFG00040016536(gene)|ensembl:ENSCAFT00000005462(transcript)|ensembl:ENSCAFT00030014054(transcript)|ensembl:ENSCAFT00040030547(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002931"(response to ischemia)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044860"(protein localization to plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060056"(mammary gland involution)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0042310"(vasoconstriction)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)|go:"GO:0005938"(cell cortex)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007595"(lactation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0015031"(protein transport)|go:"GO:0016050"(vesicle organization)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0003057"(regulation of the force of heart contraction by chemical signal)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032570"(response to progesterone)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033484"(nitric oxide homeostasis)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0038016"(insulin receptor internalization)|go:"GO:0070320"(inward rectifier potassium channel inhibitor activity)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0070836"(caveola assembly)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:2000286"(receptor internalization involved in canonical Wnt signaling pathway)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|go:"GO:1900085"(negative regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001612(Caveolin)|interpro:IPR015504(Caveolin-1)|interpro:IPR018361|reactome:R-CFA-210991|reactome:R-CFA-4641262|reactome:R-CFA-8980692|reactome:R-CFA-9009391|reactome:R-CFA-9013026|reactome:R-CFA-9013106|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903609"(negative regulation of inward rectifier potassium channel activity)|reactome:R-CFA-9013148|reactome:R-CFA-9013149|reactome:R-CFA-9013404|reactome:R-CFA-9013405|reactome:R-CFA-9013407|reactome:R-CFA-9013408|reactome:R-CFA-9035034|reactome:R-CFA-9696264|reactome:R-CFA-9696270|reactome:R-CFA-9696273|refseq:XP_005628404.1|refseq:NP_001003296.1|refseq:XP_013974350.1	-	-	-	comment:MDCK cell lysate was used.|comment:GST-fusion of aa 1-101 of CAV1 were used as bait.|comment:aa 61-101 of CAV1 are sufficient	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/12/10	2014/10/16	rogid:2ng/Mm6XYCfKLB+jODm4Vw3QCoY9615	rogid:2ng/Mm6XYCfKLB+jODm4Vw3QCoY9615	intact-crc:E6FC1DC8BDCBA199|rigid:uKKla4hhtMbDulcz1+5c+ecIQV4	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)