#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q64288 uniprotkb:Q9R224 intact:EBI-6991436|ensembl:ENSMUSP00000095882|intact:MINT-272016 intact:EBI-6991413|ensembl:ENSMUSP00000060005|ensembl:ENSMUSP00000108743|ensembl:ENSMUSP00000108745|uniprotkb:O88858|uniprotkb:Q9R1J2|intact:MINT-272048|uniprotkb:A3KGA2 psi-mi:omp_mouse(display_long)|uniprotkb:Omp(gene name)|psi-mi:Omp(display_short) psi-mi:bex1_mouse(display_long)|uniprotkb:Bex1(gene name)|psi-mi:Bex1(display_short)|uniprotkb:Rex3(gene name synonym)|uniprotkb:Brain-expressed X-linked protein 1 homolog(gene name synonym)|uniprotkb:Reduced expression protein 3(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Behrens et al. (2003) pubmed:12911636|mint:MINT-5216611 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-6991410|mint:MINT-16987 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074006(gene)|ensembl:ENSMUST00000098281(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0022008"(neurogenesis)|go:"GO:0030424"(axon)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|interpro:IPR009103(Olfactory marker protein)|interpro:IPR036727|mint:Q64288|rcsb pdb:1F35|rcsb pdb:1JOB|rcsb pdb:1JOD|refseq:NP_035140.1|mint:MINT-738225(identity) ensembl:ENSMUSG00000050071(gene)|ensembl:ENSMUST00000058125(transcript)|ensembl:ENSMUST00000113118(transcript)|ensembl:ENSMUST00000113120(transcript)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0031103"(axon regeneration)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0061564"(axon development)|interpro:IPR007623(Brain expressed X-linked like protein)|interpro:IPR021156|refseq:NP_033078.2|mint:MINT-738229(identity) - comment:mint|function:May act as a modulator of the olfactory signal-transduction cascade|comment:"Stoichiometry: 1.0" comment:mint|function:"Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states"|comment:"Stoichiometry: 1.0" comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2003/08/14 2014/10/16 rogid:5aMUjZnxAWMYTdcRnUls+HHNNgs10090 rogid:oGf6/wzW6LLPPa1G35nHFCPBvro10090 intact-crc:8093C5111285C12C|rigid:SXr+DnDt/JseOTlI3wSWUCLCR6w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q64288 uniprotkb:Q9WTZ8 intact:EBI-6991436|ensembl:ENSMUSP00000095882|intact:MINT-272016 intact:EBI-6991468|ensembl:ENSMUSP00000043113|intact:MINT-272029 psi-mi:omp_mouse(display_long)|uniprotkb:Omp(gene name)|psi-mi:Omp(display_short) psi-mi:bex2_mouse(display_long)|uniprotkb:Bex2(gene name)|psi-mi:Bex2(display_short)|uniprotkb:Brain-expressed X-linked protein 2 homolog(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Behrens et al. (2003) pubmed:12911636|mint:MINT-5216611 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-6991465|mint:MINT-16287 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074006(gene)|ensembl:ENSMUST00000098281(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0022008"(neurogenesis)|go:"GO:0030424"(axon)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|interpro:IPR009103(Olfactory marker protein)|interpro:IPR036727|mint:Q64288|rcsb pdb:1F35|rcsb pdb:1JOB|rcsb pdb:1JOD|refseq:NP_035140.1|mint:MINT-738291(identity) ensembl:ENSMUSG00000042750(gene)|ensembl:ENSMUST00000049130(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR007623(Brain expressed X-linked like protein)|interpro:IPR021156|refseq:NP_033879.1|mint:MINT-738295(identity) - comment:mint|function:May act as a modulator of the olfactory signal-transduction cascade|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2003/08/14 2014/10/16 rogid:5aMUjZnxAWMYTdcRnUls+HHNNgs10090 rogid:b9I/M21NnZcpqmwjpdzW2UzjVHg10090 intact-crc:4B2636F14F496C31|rigid:4ZXRLsl8jT3OV/dZCfvr5Gc/1wc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WTZ8 uniprotkb:Q64288 intact:EBI-6991468|ensembl:ENSMUSP00000043113|intact:MINT-272029 intact:EBI-6991436|ensembl:ENSMUSP00000095882|intact:MINT-272016 psi-mi:bex2_mouse(display_long)|uniprotkb:Bex2(gene name)|psi-mi:Bex2(display_short)|uniprotkb:Brain-expressed X-linked protein 2 homolog(gene name synonym) psi-mi:omp_mouse(display_long)|uniprotkb:Omp(gene name)|psi-mi:Omp(display_short) psi-mi:"MI:0084"(phage display) Behrens et al. (2003) pubmed:12911636|mint:MINT-5216611 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-6991498|mint:MINT-16285 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000042750(gene)|ensembl:ENSMUST00000049130(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR007623(Brain expressed X-linked like protein)|interpro:IPR021156|refseq:NP_033879.1|mint:MINT-738241(identity) ensembl:ENSMUSG00000074006(gene)|ensembl:ENSMUST00000098281(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0022008"(neurogenesis)|go:"GO:0030424"(axon)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|interpro:IPR009103(Olfactory marker protein)|interpro:IPR036727|mint:Q64288|rcsb pdb:1F35|rcsb pdb:1JOB|rcsb pdb:1JOD|refseq:NP_035140.1|mint:MINT-738237(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|function:May act as a modulator of the olfactory signal-transduction cascade|comment:"Stoichiometry: 1.0" comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2003/08/14 2014/10/16 rogid:b9I/M21NnZcpqmwjpdzW2UzjVHg10090 rogid:5aMUjZnxAWMYTdcRnUls+HHNNgs10090 intact-crc:3978B8171D2730B4|rigid:4ZXRLsl8jT3OV/dZCfvr5Gc/1wc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q64288 uniprotkb:Q9R224 intact:EBI-6991436|ensembl:ENSMUSP00000095882|intact:MINT-272016 intact:EBI-6991413|ensembl:ENSMUSP00000060005|ensembl:ENSMUSP00000108743|ensembl:ENSMUSP00000108745|uniprotkb:O88858|uniprotkb:Q9R1J2|intact:MINT-272048|uniprotkb:A3KGA2 psi-mi:omp_mouse(display_long)|uniprotkb:Omp(gene name)|psi-mi:Omp(display_short) psi-mi:bex1_mouse(display_long)|uniprotkb:Bex1(gene name)|psi-mi:Bex1(display_short)|uniprotkb:Rex3(gene name synonym)|uniprotkb:Brain-expressed X-linked protein 1 homolog(gene name synonym)|uniprotkb:Reduced expression protein 3(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Behrens et al. (2003) pubmed:12911636|mint:MINT-5216611 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-6991697|mint:MINT-16986 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074006(gene)|ensembl:ENSMUST00000098281(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0022008"(neurogenesis)|go:"GO:0030424"(axon)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|interpro:IPR009103(Olfactory marker protein)|interpro:IPR036727|mint:Q64288|rcsb pdb:1F35|rcsb pdb:1JOB|rcsb pdb:1JOD|refseq:NP_035140.1|mint:MINT-738249(identity) ensembl:ENSMUSG00000050071(gene)|ensembl:ENSMUST00000058125(transcript)|ensembl:ENSMUST00000113118(transcript)|ensembl:ENSMUST00000113120(transcript)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0031103"(axon regeneration)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0061564"(axon development)|interpro:IPR007623(Brain expressed X-linked like protein)|interpro:IPR021156|refseq:NP_033078.2|mint:MINT-738256(identity) go:"GO:0005634"(nucleus) comment:mint|function:May act as a modulator of the olfactory signal-transduction cascade|comment:"Stoichiometry: 1.0" comment:mint|function:"Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states"|comment:"Stoichiometry: 1.0" figure legend:F6|comment:mint taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2003/08/14 2014/10/16 rogid:5aMUjZnxAWMYTdcRnUls+HHNNgs10090 rogid:oGf6/wzW6LLPPa1G35nHFCPBvro10090 intact-crc:496277405392EA8C|rigid:SXr+DnDt/JseOTlI3wSWUCLCR6w false - flag tag:?-?(MINT-5206871) - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q64288 uniprotkb:Q9R224 intact:EBI-6991436|ensembl:ENSMUSP00000095882|intact:MINT-272016 intact:EBI-6991413|ensembl:ENSMUSP00000060005|ensembl:ENSMUSP00000108743|ensembl:ENSMUSP00000108745|uniprotkb:O88858|uniprotkb:Q9R1J2|intact:MINT-272048|uniprotkb:A3KGA2 psi-mi:omp_mouse(display_long)|uniprotkb:Omp(gene name)|psi-mi:Omp(display_short) psi-mi:bex1_mouse(display_long)|uniprotkb:Bex1(gene name)|psi-mi:Bex1(display_short)|uniprotkb:Rex3(gene name synonym)|uniprotkb:Brain-expressed X-linked protein 1 homolog(gene name synonym)|uniprotkb:Reduced expression protein 3(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Behrens et al. (2003) pubmed:12911636|mint:MINT-5216611 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-6991729|mint:MINT-5206877 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000074006(gene)|ensembl:ENSMUST00000098281(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0022008"(neurogenesis)|go:"GO:0030424"(axon)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|interpro:IPR009103(Olfactory marker protein)|interpro:IPR036727|mint:Q64288|rcsb pdb:1F35|rcsb pdb:1JOB|rcsb pdb:1JOD|refseq:NP_035140.1|mint:MINT-5206885(identity) ensembl:ENSMUSG00000050071(gene)|ensembl:ENSMUST00000058125(transcript)|ensembl:ENSMUST00000113118(transcript)|ensembl:ENSMUST00000113120(transcript)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0031103"(axon regeneration)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0061564"(axon development)|interpro:IPR007623(Brain expressed X-linked like protein)|interpro:IPR021156|refseq:NP_033078.2|mint:MINT-5206879(identity) go:"GO:0005737"(cytoplasm) comment:mint|function:May act as a modulator of the olfactory signal-transduction cascade comment:mint|function:"Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states" figure legend:F6|comment:mint taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2003/08/14 2014/10/16 rogid:5aMUjZnxAWMYTdcRnUls+HHNNgs10090 rogid:oGf6/wzW6LLPPa1G35nHFCPBvro10090 intact-crc:53D7671B04220D26|rigid:SXr+DnDt/JseOTlI3wSWUCLCR6w false - flag tag:?-?(MINT-5206881) - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0707"(anti tag immunostaining)