#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8K400	uniprotkb:P70452	intact:EBI-6955021|ensembl:ENSMUSP00000044535|uniprotkb:Q80TM5|uniprotkb:Q9D2F3|uniprotkb:Q8K401|intact:MINT-269206|uniprotkb:E9QLY8	intact:EBI-645716|ensembl:ENSMUSP00000033075|ensembl:ENSMUSP00000112927|uniprotkb:Q3TSL5|uniprotkb:Q3UKQ8|uniprotkb:Q80WT8	psi-mi:stxb5_mouse(display_long)|uniprotkb:Stxbp5(gene name)|psi-mi:Stxbp5(display_short)|uniprotkb:Kiaa4253(gene name synonym)|uniprotkb:Llgl3(gene name synonym)|uniprotkb:Tomosyn-1(gene name synonym)|uniprotkb:"Lethal(2) giant larvae protein homolog 3"(gene name synonym)	psi-mi:stx4_mouse(display_long)|uniprotkb:Stx4(gene name)|psi-mi:Stx4(display_short)|uniprotkb:Stx4a(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Widberg et al. (2003)	pubmed:12832401|mint:MINT-5216502	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6955055|mint:MINT-17808	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006512989.1|ensembl:ENSMUSG00000019790(gene)|ensembl:ENSMUST00000038213(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006887"(exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0015031"(protein transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0031201"(SNARE complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045159"(myosin II binding)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0099504"(synaptic vesicle cycle)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000664("Lethal(2) giant larvae protein")|interpro:IPR001680(WD40 repeat)|interpro:IPR013577(Lethal giant larvae homologue 2)|interpro:IPR013905("Lethal giant larvae (Lgl) like, C-terminal")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR042855|mint:Q8K400|mint:MINT-736389(identity)	refseq:NP_033320.1|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|ensembl:ENSMUSG00000030805(gene)|ensembl:ENSMUST00000033075(transcript)|ensembl:ENSMUST00000121705(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|dip:DIP-41399N|go:"GO:0016021"(integral component of membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016230"(sphingomyelin phosphodiesterase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030507"(spectrin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042383"(sarcolemma)|go:"GO:0042581"(specific granule)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043219"(lateral loop)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048284"(organelle fusion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903575"(cornified envelope assembly)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|mint:P70452|rcsb pdb:3PUJ|rcsb pdb:3PUK|reactome:R-MMU-114516|reactome:R-MMU-1236974|reactome:R-MMU-199992|reactome:R-MMU-449836|mint:MINT-736395(identity)	-	comment:mint|function:"Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release (By similarity). Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Competes with STXBP1 for STX1 binding. Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2003/09/30	2014/10/16	rogid:He6FcbLfm2Q2PeVKRIqsCzsdpag10090	rogid:rXjZl/EaKwHyd3Sl3aW5hbD6pbg10090	intact-crc:D5B302D60C3BD9FD|rigid:dZ09FaOYt7sR4vd4dsbK7xV59So	false	tag:?-?(MINT-736390)	tag:?-?(MINT-736396)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8K400	uniprotkb:O09044	intact:EBI-6955021|ensembl:ENSMUSP00000044535|uniprotkb:Q80TM5|uniprotkb:Q9D2F3|uniprotkb:Q8K401|intact:MINT-269206|uniprotkb:E9QLY8	intact:EBI-1812522|uniprotkb:O35620|ensembl:ENSMUSP00000028743|ensembl:ENSMUSP00000106339	psi-mi:stxb5_mouse(display_long)|uniprotkb:Stxbp5(gene name)|psi-mi:Stxbp5(display_short)|uniprotkb:Kiaa4253(gene name synonym)|uniprotkb:Llgl3(gene name synonym)|uniprotkb:Tomosyn-1(gene name synonym)|uniprotkb:"Lethal(2) giant larvae protein homolog 3"(gene name synonym)	psi-mi:snp23_mouse(display_long)|uniprotkb:Snap23(gene name)|psi-mi:Snap23(display_short)|uniprotkb:Sndt(gene name synonym)|uniprotkb:Vesicle-membrane fusion protein SNAP-23(gene name synonym)|uniprotkb:Syndet(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Widberg et al. (2003)	pubmed:12832401|mint:MINT-5216502	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6955132|mint:MINT-19019	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006512989.1|ensembl:ENSMUSG00000019790(gene)|ensembl:ENSMUST00000038213(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006887"(exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0015031"(protein transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0031201"(SNARE complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045159"(myosin II binding)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0099504"(synaptic vesicle cycle)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000664("Lethal(2) giant larvae protein")|interpro:IPR001680(WD40 repeat)|interpro:IPR013577(Lethal giant larvae homologue 2)|interpro:IPR013905("Lethal giant larvae (Lgl) like, C-terminal")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR042855|mint:Q8K400|mint:MINT-736415(identity)	refseq:XP_006499120.1|refseq:NP_001171263.1|refseq:NP_001171264.1|refseq:NP_033248.1|dip:DIP-41401N|ensembl:ENSMUSG00000027287(gene)|ensembl:ENSMUST00000028743(transcript)|ensembl:ENSMUST00000110711(transcript)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0043005"(neuron projection)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|reactome:R-MMU-1236974|reactome:R-MMU-199992|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406|reactome:R-MMU-9013423|reactome:R-MMU-9035034|mint:MINT-736421(identity)	-	comment:mint|function:"Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release (By similarity). Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Competes with STXBP1 for STX1 binding. Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2003/09/30	2014/10/16	rogid:He6FcbLfm2Q2PeVKRIqsCzsdpag10090	rogid:x9MAn2ftkIOcj+VDRn8omysTxns10090	intact-crc:964ED88CF3342F9B|rigid:JAzv0OAd2re94ZK9qybC5moD/KM	false	tag:?-?(MINT-736416)	tag:?-?(MINT-736422)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8K400	uniprotkb:P70452	intact:EBI-6955021|ensembl:ENSMUSP00000044535|uniprotkb:Q80TM5|uniprotkb:Q9D2F3|uniprotkb:Q8K401|intact:MINT-269206|uniprotkb:E9QLY8	intact:EBI-645716|ensembl:ENSMUSP00000033075|ensembl:ENSMUSP00000112927|uniprotkb:Q3TSL5|uniprotkb:Q3UKQ8|uniprotkb:Q80WT8	psi-mi:stxb5_mouse(display_long)|uniprotkb:Stxbp5(gene name)|psi-mi:Stxbp5(display_short)|uniprotkb:Kiaa4253(gene name synonym)|uniprotkb:Llgl3(gene name synonym)|uniprotkb:Tomosyn-1(gene name synonym)|uniprotkb:"Lethal(2) giant larvae protein homolog 3"(gene name synonym)	psi-mi:stx4_mouse(display_long)|uniprotkb:Stx4(gene name)|psi-mi:Stx4(display_short)|uniprotkb:Stx4a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Widberg et al. (2003)	pubmed:12832401|mint:MINT-5216502	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-6955174|mint:MINT-17809	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006512989.1|ensembl:ENSMUSG00000019790(gene)|ensembl:ENSMUST00000038213(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006887"(exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0015031"(protein transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0031201"(SNARE complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045159"(myosin II binding)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0099504"(synaptic vesicle cycle)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000664("Lethal(2) giant larvae protein")|interpro:IPR001680(WD40 repeat)|interpro:IPR013577(Lethal giant larvae homologue 2)|interpro:IPR013905("Lethal giant larvae (Lgl) like, C-terminal")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR042855|mint:Q8K400|mint:MINT-736406(identity)	refseq:NP_033320.1|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|ensembl:ENSMUSG00000030805(gene)|ensembl:ENSMUST00000033075(transcript)|ensembl:ENSMUST00000121705(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|dip:DIP-41399N|go:"GO:0016021"(integral component of membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016230"(sphingomyelin phosphodiesterase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030507"(spectrin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042383"(sarcolemma)|go:"GO:0042581"(specific granule)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043219"(lateral loop)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048284"(organelle fusion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903575"(cornified envelope assembly)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|mint:P70452|rcsb pdb:3PUJ|rcsb pdb:3PUK|reactome:R-MMU-114516|reactome:R-MMU-1236974|reactome:R-MMU-199992|reactome:R-MMU-449836|mint:MINT-736409(identity)	-	comment:mint|function:"Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release (By similarity). Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Competes with STXBP1 for STX1 binding. Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/09/30	2014/10/16	rogid:He6FcbLfm2Q2PeVKRIqsCzsdpag10090	rogid:rXjZl/EaKwHyd3Sl3aW5hbD6pbg10090	intact-crc:F7E3300E46BA7936|rigid:dZ09FaOYt7sR4vd4dsbK7xV59So	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8K400	uniprotkb:O09044	intact:EBI-6955021|ensembl:ENSMUSP00000044535|uniprotkb:Q80TM5|uniprotkb:Q9D2F3|uniprotkb:Q8K401|intact:MINT-269206|uniprotkb:E9QLY8	intact:EBI-1812522|uniprotkb:O35620|ensembl:ENSMUSP00000028743|ensembl:ENSMUSP00000106339	psi-mi:stxb5_mouse(display_long)|uniprotkb:Stxbp5(gene name)|psi-mi:Stxbp5(display_short)|uniprotkb:Kiaa4253(gene name synonym)|uniprotkb:Llgl3(gene name synonym)|uniprotkb:Tomosyn-1(gene name synonym)|uniprotkb:"Lethal(2) giant larvae protein homolog 3"(gene name synonym)	psi-mi:snp23_mouse(display_long)|uniprotkb:Snap23(gene name)|psi-mi:Snap23(display_short)|uniprotkb:Sndt(gene name synonym)|uniprotkb:Vesicle-membrane fusion protein SNAP-23(gene name synonym)|uniprotkb:Syndet(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Widberg et al. (2003)	pubmed:12832401|mint:MINT-5216502	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-6955192|mint:MINT-19020	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006512989.1|ensembl:ENSMUSG00000019790(gene)|ensembl:ENSMUST00000038213(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006887"(exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0015031"(protein transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0031201"(SNARE complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045159"(myosin II binding)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0099504"(synaptic vesicle cycle)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000664("Lethal(2) giant larvae protein")|interpro:IPR001680(WD40 repeat)|interpro:IPR013577(Lethal giant larvae homologue 2)|interpro:IPR013905("Lethal giant larvae (Lgl) like, C-terminal")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR042855|mint:Q8K400|mint:MINT-736432(identity)	refseq:XP_006499120.1|refseq:NP_001171263.1|refseq:NP_001171264.1|refseq:NP_033248.1|dip:DIP-41401N|ensembl:ENSMUSG00000027287(gene)|ensembl:ENSMUST00000028743(transcript)|ensembl:ENSMUST00000110711(transcript)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0043005"(neuron projection)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|reactome:R-MMU-1236974|reactome:R-MMU-199992|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406|reactome:R-MMU-9013423|reactome:R-MMU-9035034|mint:MINT-736435(identity)	-	comment:mint|function:"Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release (By similarity). Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Competes with STXBP1 for STX1 binding. Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2003/09/30	2014/10/16	rogid:He6FcbLfm2Q2PeVKRIqsCzsdpag10090	rogid:x9MAn2ftkIOcj+VDRn8omysTxns10090	intact-crc:9A191D879F3E76CF|rigid:JAzv0OAd2re94ZK9qybC5moD/KM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)