#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q16649	uniprotkb:Q16649	intact:EBI-3951858|uniprotkb:B2R9Y8|uniprotkb:Q14211|uniprotkb:Q6FGQ8|uniprotkb:Q96HS0|ensembl:ENSP00000297689	intact:EBI-3951858|uniprotkb:B2R9Y8|uniprotkb:Q14211|uniprotkb:Q6FGQ8|uniprotkb:Q96HS0|ensembl:ENSP00000297689	psi-mi:nfil3_human(display_long)|uniprotkb:NFIL3(gene name)|psi-mi:NFIL3(display_short)|uniprotkb:E4BP4(gene name synonym)|uniprotkb:IL3BP1(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Interleukin-3 promoter transcriptional activator(gene name synonym)|uniprotkb:Interleukin-3-binding protein 1(gene name synonym)|uniprotkb:Transcriptional activator NF-IL3A(gene name synonym)	psi-mi:nfil3_human(display_long)|uniprotkb:NFIL3(gene name)|psi-mi:NFIL3(display_short)|uniprotkb:E4BP4(gene name synonym)|uniprotkb:IL3BP1(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Interleukin-3 promoter transcriptional activator(gene name synonym)|uniprotkb:Interleukin-3-binding protein 1(gene name synonym)|uniprotkb:Transcriptional activator NF-IL3A(gene name synonym)	psi-mi:"MI:0081"(peptide array)	Newman et al. (2003)	pubmed:12805554|mint:MINT-5216464	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-6942813|mint:MINT-19430	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005375.2|ensembl:ENSG00000165030(gene)|ensembl:ENST00000297689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:Q16649|reactome:R-HSA-400253|go:"GO:0000785"(chromatin)|refseq:NP_001276928.1|refseq:NP_001276929.1|refseq:XP_016870232.1|refseq:XP_016870233.1|mint:MINT-735634(identity)	refseq:NP_005375.2|ensembl:ENSG00000165030(gene)|ensembl:ENST00000297689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:Q16649|reactome:R-HSA-400253|go:"GO:0000785"(chromatin)|refseq:NP_001276928.1|refseq:NP_001276929.1|refseq:XP_016870232.1|refseq:XP_016870233.1|mint:MINT-735640(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/12/01	2014/10/16	rogid:Ra9G92z80ogAKLGyDNnUudk8n8I9606	rogid:Ra9G92z80ogAKLGyDNnUudk8n8I9606	intact-crc:8B38750ECD632067|rigid:uWpsfQsD3ygxDAc3iBpvbiUnLJg	false	binding-associated region:?-?(MINT-735635)	binding-associated region:?-?(MINT-735641)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P18850	uniprotkb:P18850	intact:EBI-852157|uniprotkb:O15139|uniprotkb:Q5VW62|uniprotkb:Q6IPB5|uniprotkb:Q9UEC9|ensembl:ENSP00000356919|ensembl:ENSP00000505025|ensembl:ENSP00000505998	intact:EBI-852157|uniprotkb:O15139|uniprotkb:Q5VW62|uniprotkb:Q6IPB5|uniprotkb:Q9UEC9|ensembl:ENSP00000356919|ensembl:ENSP00000505025|ensembl:ENSP00000505998	psi-mi:atf6a_human(display_long)|uniprotkb:Activating transcription factor 6 alpha(gene name synonym)|uniprotkb:ATF6(gene name)|psi-mi:ATF6(display_short)	psi-mi:atf6a_human(display_long)|uniprotkb:Activating transcription factor 6 alpha(gene name synonym)|uniprotkb:ATF6(gene name)|psi-mi:ATF6(display_short)	psi-mi:"MI:0081"(peptide array)	Newman et al. (2003)	pubmed:12805554|mint:MINT-5216464	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-6942848|mint:MINT-19431	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_031374.2|dip:DIP-29304N|ensembl:ENSG00000118217(gene)|ensembl:ENST00000367942(transcript)|ensembl:ENST00000681738(transcript)|ensembl:ENST00000681801(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006457"(protein folding)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903893"(positive regulation of ATF6-mediated unfolded protein response)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029801|mint:P18850|reactome:R-HSA-380994|reactome:R-HSA-381033|reactome:R-HSA-381183|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|mint:MINT-735664(identity)	refseq:NP_031374.2|dip:DIP-29304N|ensembl:ENSG00000118217(gene)|ensembl:ENST00000367942(transcript)|ensembl:ENST00000681738(transcript)|ensembl:ENST00000681801(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006457"(protein folding)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903893"(positive regulation of ATF6-mediated unfolded protein response)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029801|mint:P18850|reactome:R-HSA-380994|reactome:R-HSA-381033|reactome:R-HSA-381183|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|mint:MINT-735670(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/12/01	2014/10/16	rogid:mIU7Apng6rQ423SQnZTsceVSRus9606	rogid:mIU7Apng6rQ423SQnZTsceVSRus9606	intact-crc:847E03DCC35E3910|rigid:YOTiTLWJHxp+/AwDOhJ4BgBg9uA	false	binding-associated region:?-?(MINT-735665)	binding-associated region:?-?(MINT-735671)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96BA8	uniprotkb:Q96BA8	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:"MI:0081"(peptide array)	Newman et al. (2003)	pubmed:12805554|mint:MINT-5216464	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-6942898|mint:MINT-19433	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|mint:MINT-735679(identity)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|mint:MINT-735685(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"|comment:"Stoichiometry: 1.0"	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"|comment:"Stoichiometry: 1.0"	figure legend:F2|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/12/01	2014/10/16	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	intact-crc:41E94FBEF39CAFA1|rigid:lw8pCQ9CIkgmBM8bjgRSW9KFyvw	false	binding-associated region:?-?(MINT-735680)	binding-associated region:?-?(MINT-735686)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17861	uniprotkb:P17861	intact:EBI-6942961|ensembl:ENSP00000216037|uniprotkb:Q969P1|intact:MINT-268152|uniprotkb:Q96BD7|uniprotkb:Q8WYK6	intact:EBI-6942961|ensembl:ENSP00000216037|uniprotkb:Q969P1|intact:MINT-268152|uniprotkb:Q96BD7|uniprotkb:Q8WYK6	psi-mi:xbp1_human(display_long)|uniprotkb:XBP1(gene name)|psi-mi:XBP1(display_short)|uniprotkb:TREB5(gene name synonym)|uniprotkb:XBP2(gene name synonym)|uniprotkb:Tax-responsive element-binding protein 5(gene name synonym)	psi-mi:xbp1_human(display_long)|uniprotkb:XBP1(gene name)|psi-mi:XBP1(display_short)|uniprotkb:TREB5(gene name synonym)|uniprotkb:XBP2(gene name synonym)|uniprotkb:Tax-responsive element-binding protein 5(gene name synonym)	psi-mi:"MI:0081"(peptide array)	Newman et al. (2003)	pubmed:12805554|mint:MINT-5216464	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-6942995|mint:MINT-19434	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100219(gene)|ensembl:ENST00000216037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0006996"(organelle organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:1900100"(positive regulation of plasma cell differentiation)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:6R5Q|rcsb pdb:6R6G|rcsb pdb:6R6P|rcsb pdb:6R7Q|reactome:R-HSA-381038|reactome:R-HSA-381070|reactome:R-HSA-381183|go:"GO:0071499"(cellular response to laminar fluid shear stress)|refseq:NP_001073007.1|refseq:NP_005071.2|dip:DIP-41692N|mint:MINT-735649(identity)	ensembl:ENSG00000100219(gene)|ensembl:ENST00000216037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0006996"(organelle organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:1900100"(positive regulation of plasma cell differentiation)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:6R5Q|rcsb pdb:6R6G|rcsb pdb:6R6P|rcsb pdb:6R7Q|reactome:R-HSA-381038|reactome:R-HSA-381070|reactome:R-HSA-381183|go:"GO:0071499"(cellular response to laminar fluid shear stress)|refseq:NP_001073007.1|refseq:NP_005071.2|dip:DIP-41692N|mint:MINT-735655(identity)	-	function:"Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I"|comment:mint|comment:"Stoichiometry: 1.0"	function:"Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I"|comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F2|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/12/01	2014/10/16	rogid:6QLd4DW85tnOCNFdL+hFZOPniEo9606	rogid:6QLd4DW85tnOCNFdL+hFZOPniEo9606	intact-crc:6E706B56ACF58F88|rigid:fB1lHAyYtYIKYl7lCgUafp9ESwc	false	binding-associated region:?-?(MINT-735650)	binding-associated region:?-?(MINT-735656)	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0056"(full identification by DNA sequencing)