#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O43157	uniprotkb:Q92730	intact:EBI-1111488|uniprotkb:Q6NY20|uniprotkb:Q9UIV7|uniprotkb:Q9UJ92|uniprotkb:Q9UJ93|uniprotkb:A6H8Y2|ensembl:ENSP00000296440|ensembl:ENSP00000351338	intact:EBI-448618|uniprotkb:A8K9P7|ensembl:ENSP00000308461	psi-mi:plxb1_human(display_long)|uniprotkb:PLXNB1(gene name)|psi-mi:PLXNB1(display_short)|uniprotkb:KIAA0407(gene name synonym)|uniprotkb:SEP(gene name synonym)|uniprotkb:Semaphorin receptor SEP(gene name synonym)|uniprotkb:PLXN5(gene name synonym)	psi-mi:rnd1_human(display_long)|uniprotkb:RND1(gene name)|psi-mi:RND1(display_short)|uniprotkb:RHO6(gene name synonym)|uniprotkb:Rho family GTPase 1(gene name synonym)|uniprotkb:Rnd1(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Oinuma et al. (2003)	mint:MINT-5216356|pubmed:12730235	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8641599|mint:MINT-16325	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2JPH|rcsb pdb:2OS6|rcsb pdb:2R2O|rcsb pdb:2REX|rcsb pdb:3HM6|rcsb pdb:3OL2|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:5B4W|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|refseq:NP_001123554.1|refseq:NP_002664.2|ensembl:ENSG00000164050(gene)|ensembl:ENST00000296440(transcript)|ensembl:ENST00000358536(transcript)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1900220"(semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:1904862"(inhibitory synapse assembly)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|mint:O43157|refseq:XP_016862120.1|dip:DIP-36742N|mint:MINT-733684(identity)	refseq:NP_055285.1|dip:DIP-36741N|ensembl:ENSG00000172602(gene)|ensembl:ENST00000309739(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2CLS|rcsb pdb:2REX|rcsb pdb:3Q3J|reactome:R-HSA-399955|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-9696273|mint:MINT-733681(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2003/08/04	2014/10/16	rogid:wWC3lipQ3PIBCvCjt5t2gQTAXro9606	rogid:phz3xjUx3hNvqd/BE+e6Zjb2n7g9606	intact-crc:0B01F13EF2AB2040|rigid:qK64kTqrAxfMYsIWl9Xa4Fm2EkE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43157	uniprotkb:Q92730	intact:EBI-1111488|uniprotkb:Q6NY20|uniprotkb:Q9UIV7|uniprotkb:Q9UJ92|uniprotkb:Q9UJ93|uniprotkb:A6H8Y2|ensembl:ENSP00000296440|ensembl:ENSP00000351338	intact:EBI-448618|uniprotkb:A8K9P7|ensembl:ENSP00000308461	psi-mi:plxb1_human(display_long)|uniprotkb:PLXNB1(gene name)|psi-mi:PLXNB1(display_short)|uniprotkb:KIAA0407(gene name synonym)|uniprotkb:SEP(gene name synonym)|uniprotkb:Semaphorin receptor SEP(gene name synonym)|uniprotkb:PLXN5(gene name synonym)	psi-mi:rnd1_human(display_long)|uniprotkb:RND1(gene name)|psi-mi:RND1(display_short)|uniprotkb:RHO6(gene name synonym)|uniprotkb:Rho family GTPase 1(gene name synonym)|uniprotkb:Rnd1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Oinuma et al. (2003)	mint:MINT-5216356|pubmed:12730235	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8641634|mint:MINT-16324	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2JPH|rcsb pdb:2OS6|rcsb pdb:2R2O|rcsb pdb:2REX|rcsb pdb:3HM6|rcsb pdb:3OL2|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:5B4W|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|refseq:NP_001123554.1|refseq:NP_002664.2|ensembl:ENSG00000164050(gene)|ensembl:ENST00000296440(transcript)|ensembl:ENST00000358536(transcript)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1900220"(semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:1904862"(inhibitory synapse assembly)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|mint:O43157|refseq:XP_016862120.1|dip:DIP-36742N|mint:MINT-733697(identity)	refseq:NP_055285.1|dip:DIP-36741N|ensembl:ENSG00000172602(gene)|ensembl:ENST00000309739(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2CLS|rcsb pdb:2REX|rcsb pdb:3Q3J|reactome:R-HSA-399955|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-9696273|mint:MINT-733691(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2003/08/04	2014/10/16	rogid:wWC3lipQ3PIBCvCjt5t2gQTAXro9606	rogid:phz3xjUx3hNvqd/BE+e6Zjb2n7g9606	intact-crc:86CAFA433FB683E7|rigid:qK64kTqrAxfMYsIWl9Xa4Fm2EkE	false	tag:?-?(MINT-733698)	tag:?-?(MINT-733692)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)