#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P05412 uniprotkb:Q8NHY2 intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7|ensembl:ENSP00000360266|ensembl:ENSP00000503132 intact:EBI-1176214|uniprotkb:Q6H103|uniprotkb:Q9H6L7|ensembl:ENSP00000356641|intact:EBI-5280824|uniprotkb:Q504W6|uniprotkb:E9PKI0|uniprotkb:X5D9B4 psi-mi:jun_human(display_long)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym) psi-mi:cop1_human(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:Constitutive photomorphogenesis protein 1 homolog(gene name synonym)|uniprotkb:RFWD2(gene name synonym)|uniprotkb:RING finger and WD repeat domain protein 2(gene name synonym)|uniprotkb:RING finger protein 200(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RFWD2(gene name synonym)|uniprotkb:RNF200(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Bianchi et al. (2003) mint:MINT-5216178|pubmed:12615916 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8616749|mint:MINT-19379 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002219.1|ensembl:ENSP00000360266|ensembl:ENSP00000503132|dip:DIP-5961N|ensembl:ENSG00000177606(gene)|ensembl:ENST00000371222(transcript)|ensembl:ENST00000678696(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR015558(c-Jun Transcription Factor)|mint:P05412|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|rcsb pdb:5FV8|rcsb pdb:5T01|rcsb pdb:6Y3V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-6796648|reactome:R-HSA-8862803|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9673324|mint:MINT-730000(identity) refseq:NP_001001740.1|refseq:NP_071902.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017907|interpro:IPR019775|interpro:IPR036322|interpro:IPR042755|rcsb pdb:5HQG|rcsb pdb:5IGQ|reactome:R-HSA-349425|reactome:R-HSA-8951664|refseq:NP_001273573.1|ensembl:ENSG00000143207(gene)|ensembl:ENST00000367669(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENST00000308769|ensembl:ENSP00000310943|ensembl:ENSP00000356641|ensembl:ENST00000474194|ensembl:ENSP00000433517|dip:DIP-36661N|mint:MINT-729992(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2003/11/18 2014/10/16 rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606 rogid:/L++lerkGxqk+69cp6ExrCCL4hs9606 intact-crc:F6DB6F0763200BA7|rigid:ZmAniRjpOpn06yqapzuhpMQMU5Q false binding-associated region:219-244(MINT-730001) binding-associated region:?-?(MINT-729993)|tag:?-?(MINT-729995) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8NHY2 uniprotkb:P17535 intact:EBI-1176214|uniprotkb:Q6H103|uniprotkb:Q9H6L7|ensembl:ENSP00000356641|intact:EBI-5280824|uniprotkb:Q504W6|uniprotkb:E9PKI0|uniprotkb:X5D9B4 intact:EBI-2682803|uniprotkb:Q53EK9|ensembl:ENSP00000252818 psi-mi:cop1_human(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:Constitutive photomorphogenesis protein 1 homolog(gene name synonym)|uniprotkb:RFWD2(gene name synonym)|uniprotkb:RING finger and WD repeat domain protein 2(gene name synonym)|uniprotkb:RING finger protein 200(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RFWD2(gene name synonym)|uniprotkb:RNF200(gene name synonym) psi-mi:jund_human(display_long)|uniprotkb:JUND(gene name)|psi-mi:JUND(display_short) psi-mi:"MI:0019"(coimmunoprecipitation) Bianchi et al. (2003) mint:MINT-5216178|pubmed:12615916 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8616770|mint:MINT-19380 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001740.1|refseq:NP_071902.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017907|interpro:IPR019775|interpro:IPR036322|interpro:IPR042755|rcsb pdb:5HQG|rcsb pdb:5IGQ|reactome:R-HSA-349425|reactome:R-HSA-8951664|refseq:NP_001273573.1|ensembl:ENSG00000143207(gene)|ensembl:ENST00000367669(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENST00000308769|ensembl:ENSP00000310943|ensembl:ENSP00000356641|ensembl:ENST00000474194|ensembl:ENSP00000433517|dip:DIP-36661N|mint:MINT-729976(identity) refseq:NP_001273897.1|refseq:NP_005345.3|ensembl:ENSG00000130522(gene)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|ensembl:ENST00000252818(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR029823|mint:P17535|rcsb pdb:3U86|rcsb pdb:5VPA|rcsb pdb:5VPB|rcsb pdb:5VPC|rcsb pdb:5VPD|rcsb pdb:5VPE|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:5VPF|reactome:R-HSA-9018519|reactome:R-HSA-9031628|go:"GO:0002076"(osteoblast development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007568"(aging)|dip:DIP-1053N|mint:MINT-729984(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2003/11/18 2014/10/16 rogid:/L++lerkGxqk+69cp6ExrCCL4hs9606 rogid:npmTGULvlKr4hC8HfmK19GUopf49606 intact-crc:3829230644FAFBD7|rigid:alIUq5Dqp0MscEC4xfdn0iMFDqo false tag:?-?(MINT-729979)|binding-associated region:?-?(MINT-729977) binding-associated region:233-258(MINT-729985) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)