#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O14649	uniprotkb:P31946	intact:EBI-8559445|intact:MINT-1645466|uniprotkb:Q53SU2|ensembl:ENSP00000306275	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930	psi-mi:kcnk3_human(display_long)|uniprotkb:KCNK3(gene name)|psi-mi:KCNK3(display_short)|uniprotkb:TASK(gene name synonym)|uniprotkb:TASK1(gene name synonym)|uniprotkb:Acid-sensitive potassium channel protein TASK-1(gene name synonym)|uniprotkb:"TWIK-related acid-sensitive K(+) channel 1"(gene name synonym)|uniprotkb:Two pore potassium channel KT3.1(gene name synonym)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	psi-mi:"MI:0096"(pull down)	O'Kelly et al. (2002)	pubmed:12437930|mint:MINT-5215921	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8559477|mint:MINT-15089	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002237.1|ensembl:ENSG00000171303(gene)|ensembl:ENST00000302909(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005252"(open rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042493"|go:"GO:0044548"(S100 protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|interpro:IPR003092(Potassium channel, two pore-domain, TASK)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR005406(Potassium channel, two pore-domain, TASK-1)|interpro:IPR013099(Ion transport 2)|rcsb pdb:6RV2|rcsb pdb:6RV3|rcsb pdb:6RV4|reactome:R-HSA-1299316|reactome:R-HSA-5576886|mint:MINT-1645491(identity)	refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N|mint:MINT-1645488(identity)	-	comment:mint|function:pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/03/17	2014/10/16	rogid:DCgyygIkuz0HccOjC7nXdXS29Gk9606	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	intact-crc:5758E42098EFCCAC|rigid:zkv9XFxkGDnnXAgd/4AFnJgW8Ls	false	O-phospho-L-serine:393-393(MINT-1645494)|binding-associated region:390-394(MINT-1645492)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14649	uniprotkb:P31946	intact:EBI-8559445|intact:MINT-1645466|uniprotkb:Q53SU2|ensembl:ENSP00000306275	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930	psi-mi:kcnk3_human(display_long)|uniprotkb:KCNK3(gene name)|psi-mi:KCNK3(display_short)|uniprotkb:TASK(gene name synonym)|uniprotkb:TASK1(gene name synonym)|uniprotkb:Acid-sensitive potassium channel protein TASK-1(gene name synonym)|uniprotkb:"TWIK-related acid-sensitive K(+) channel 1"(gene name synonym)|uniprotkb:Two pore potassium channel KT3.1(gene name synonym)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	psi-mi:"MI:0428"(imaging technique)	O'Kelly et al. (2002)	pubmed:12437930|mint:MINT-5215921	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8559551|mint:MINT-15088	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002237.1|ensembl:ENSG00000171303(gene)|ensembl:ENST00000302909(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005252"(open rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042493"|go:"GO:0044548"(S100 protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|interpro:IPR003092(Potassium channel, two pore-domain, TASK)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR005406(Potassium channel, two pore-domain, TASK-1)|interpro:IPR013099(Ion transport 2)|rcsb pdb:6RV2|rcsb pdb:6RV3|rcsb pdb:6RV4|reactome:R-HSA-1299316|reactome:R-HSA-5576886|mint:MINT-1660543(identity)	refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N|mint:MINT-1660540(identity)	-	comment:mint|function:pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2003/03/17	2014/10/16	rogid:DCgyygIkuz0HccOjC7nXdXS29Gk9606	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	intact-crc:958868A3BB8BF4BB|rigid:zkv9XFxkGDnnXAgd/4AFnJgW8Ls	false	binding-associated region:390-394(MINT-1660544)|O-phospho-L-serine:393-393(MINT-1660546)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14649	uniprotkb:P31946	intact:EBI-8559445|intact:MINT-1645466|uniprotkb:Q53SU2|ensembl:ENSP00000306275	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930	psi-mi:kcnk3_human(display_long)|uniprotkb:KCNK3(gene name)|psi-mi:KCNK3(display_short)|uniprotkb:TASK(gene name synonym)|uniprotkb:TASK1(gene name synonym)|uniprotkb:Acid-sensitive potassium channel protein TASK-1(gene name synonym)|uniprotkb:"TWIK-related acid-sensitive K(+) channel 1"(gene name synonym)|uniprotkb:Two pore potassium channel KT3.1(gene name synonym)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	O'Kelly et al. (2002)	pubmed:12437930|mint:MINT-5215921	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8559599|mint:MINT-8006209	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002237.1|ensembl:ENSG00000171303(gene)|ensembl:ENST00000302909(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005252"(open rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042493"|go:"GO:0044548"(S100 protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|interpro:IPR003092(Potassium channel, two pore-domain, TASK)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR005406(Potassium channel, two pore-domain, TASK-1)|interpro:IPR013099(Ion transport 2)|rcsb pdb:6RV2|rcsb pdb:6RV3|rcsb pdb:6RV4|reactome:R-HSA-1299316|reactome:R-HSA-5576886|mint:MINT-8006213(identity)|uniprotkb:O14649(original identifier)	refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N|mint:MINT-8006210(identity)|uniprotkb:P31946(original identifier)	-	comment:mint|function:pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward	-	comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2003/03/17	2014/10/16	rogid:DCgyygIkuz0HccOjC7nXdXS29Gk9606	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	intact-crc:6BAB293E8FF8106A|rigid:zkv9XFxkGDnnXAgd/4AFnJgW8Ls	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14649	uniprotkb:P31946	intact:EBI-8559445|intact:MINT-1645466|uniprotkb:Q53SU2|ensembl:ENSP00000306275	intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930	psi-mi:kcnk3_human(display_long)|uniprotkb:KCNK3(gene name)|psi-mi:KCNK3(display_short)|uniprotkb:TASK(gene name synonym)|uniprotkb:TASK1(gene name synonym)|uniprotkb:Acid-sensitive potassium channel protein TASK-1(gene name synonym)|uniprotkb:"TWIK-related acid-sensitive K(+) channel 1"(gene name synonym)|uniprotkb:Two pore potassium channel KT3.1(gene name synonym)	psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	O'Kelly et al. (2002)	pubmed:12437930|mint:MINT-5215921	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8559683|mint:MINT-8006231	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002237.1|ensembl:ENSG00000171303(gene)|ensembl:ENST00000302909(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005252"(open rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042493"|go:"GO:0044548"(S100 protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|interpro:IPR003092(Potassium channel, two pore-domain, TASK)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR005406(Potassium channel, two pore-domain, TASK-1)|interpro:IPR013099(Ion transport 2)|rcsb pdb:6RV2|rcsb pdb:6RV3|rcsb pdb:6RV4|reactome:R-HSA-1299316|reactome:R-HSA-5576886|mint:MINT-8006235(identity)|uniprotkb:O14649(original identifier)	refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N|mint:MINT-8006232(identity)|uniprotkb:P31946(original identifier)	-	comment:mint|function:pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward	-	comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2003/03/17	2014/10/16	rogid:DCgyygIkuz0HccOjC7nXdXS29Gk9606	rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606	intact-crc:6BAB293E8FF8106A|rigid:zkv9XFxkGDnnXAgd/4AFnJgW8Ls	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14649	uniprotkb:P35213	intact:EBI-8559445|intact:MINT-1645466|uniprotkb:Q53SU2|ensembl:ENSP00000306275	intact:EBI-917309|ensembl:ENSRNOP00000016981	psi-mi:kcnk3_human(display_long)|uniprotkb:KCNK3(gene name)|psi-mi:KCNK3(display_short)|uniprotkb:TASK(gene name synonym)|uniprotkb:TASK1(gene name synonym)|uniprotkb:Acid-sensitive potassium channel protein TASK-1(gene name synonym)|uniprotkb:"TWIK-related acid-sensitive K(+) channel 1"(gene name synonym)|uniprotkb:Two pore potassium channel KT3.1(gene name synonym)	psi-mi:1433b_rat(display_long)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Prepronerve growth factor RNH-1(gene name synonym)|uniprotkb:Ywhab(gene name)|psi-mi:Ywhab(display_short)	psi-mi:"MI:0019"(coimmunoprecipitation)	O'Kelly et al. (2002)	pubmed:12437930|mint:MINT-5215921	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8559652|mint:MINT-8006220	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002237.1|ensembl:ENSG00000171303(gene)|ensembl:ENST00000302909(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005252"(open rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042493"|go:"GO:0044548"(S100 protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|interpro:IPR003092(Potassium channel, two pore-domain, TASK)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR005406(Potassium channel, two pore-domain, TASK-1)|interpro:IPR013099(Ion transport 2)|rcsb pdb:6RV2|rcsb pdb:6RV3|rcsb pdb:6RV4|reactome:R-HSA-1299316|reactome:R-HSA-5576886|mint:MINT-8006224(identity)|uniprotkb:O14649(original identifier)	rgd:61998|refseq:NP_062250.1|ensembl:ENSRNOG00000010945(gene)|ensembl:ENSRNOT00000016981(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P35213|reactome:R-RNO-111447|reactome:R-RNO-165159|reactome:R-RNO-166208|reactome:R-RNO-170968|reactome:R-RNO-2028269|reactome:R-RNO-392517|reactome:R-RNO-450385|reactome:R-RNO-450513|reactome:R-RNO-5625740|reactome:R-RNO-5628897|reactome:R-RNO-5673000|reactome:R-RNO-5674135|reactome:R-RNO-5675221|reactome:R-RNO-75035|reactome:R-RNO-9614399|mint:MINT-8006221(identity)|uniprotkb:P35213(original identifier)	-	comment:mint|function:pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward	-	comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2003/03/17	2014/10/16	rogid:DCgyygIkuz0HccOjC7nXdXS29Gk9606	rogid:L/MyYCTZ4ws1GPmT1Jyxa7gVcg010116	intact-crc:4FD2ABFCB2C60E69|rigid:HumWYpSRulBK64iYXLGRqm1kKgA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14649	uniprotkb:P35213	intact:EBI-8559445|intact:MINT-1645466|uniprotkb:Q53SU2|ensembl:ENSP00000306275	intact:EBI-917309|ensembl:ENSRNOP00000016981	psi-mi:kcnk3_human(display_long)|uniprotkb:KCNK3(gene name)|psi-mi:KCNK3(display_short)|uniprotkb:TASK(gene name synonym)|uniprotkb:TASK1(gene name synonym)|uniprotkb:Acid-sensitive potassium channel protein TASK-1(gene name synonym)|uniprotkb:"TWIK-related acid-sensitive K(+) channel 1"(gene name synonym)|uniprotkb:Two pore potassium channel KT3.1(gene name synonym)	psi-mi:1433b_rat(display_long)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Prepronerve growth factor RNH-1(gene name synonym)|uniprotkb:Ywhab(gene name)|psi-mi:Ywhab(display_short)	psi-mi:"MI:0096"(pull down)	O'Kelly et al. (2002)	pubmed:12437930|mint:MINT-5215921	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8559723|mint:MINT-8006241	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002237.1|ensembl:ENSG00000171303(gene)|ensembl:ENST00000302909(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005252"(open rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042493"|go:"GO:0044548"(S100 protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|interpro:IPR003092(Potassium channel, two pore-domain, TASK)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR005406(Potassium channel, two pore-domain, TASK-1)|interpro:IPR013099(Ion transport 2)|rcsb pdb:6RV2|rcsb pdb:6RV3|rcsb pdb:6RV4|reactome:R-HSA-1299316|reactome:R-HSA-5576886|mint:MINT-8006245(identity)|uniprotkb:O14649(original identifier)	rgd:61998|refseq:NP_062250.1|ensembl:ENSRNOG00000010945(gene)|ensembl:ENSRNOT00000016981(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P35213|reactome:R-RNO-111447|reactome:R-RNO-165159|reactome:R-RNO-166208|reactome:R-RNO-170968|reactome:R-RNO-2028269|reactome:R-RNO-392517|reactome:R-RNO-450385|reactome:R-RNO-450513|reactome:R-RNO-5625740|reactome:R-RNO-5628897|reactome:R-RNO-5673000|reactome:R-RNO-5674135|reactome:R-RNO-5675221|reactome:R-RNO-75035|reactome:R-RNO-9614399|mint:MINT-8006242(identity)|uniprotkb:P35213(original identifier)	-	comment:mint|function:pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward	-	comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2003/03/17	2014/10/16	rogid:DCgyygIkuz0HccOjC7nXdXS29Gk9606	rogid:L/MyYCTZ4ws1GPmT1Jyxa7gVcg010116	intact-crc:3998634AFB4DF8FD|rigid:HumWYpSRulBK64iYXLGRqm1kKgA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)