#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P46821	uniprotkb:Q9H2C0	intact:EBI-764611|uniprotkb:A2BDK5|ensembl:ENSP00000296755	intact:EBI-764342|ensembl:ENSP00000497351	psi-mi:map1b_human(display_long)|uniprotkb:MAP1B(gene name)|psi-mi:MAP1B(display_short)	psi-mi:gan_human(display_long)|uniprotkb:Kelch-like protein 16(gene name synonym)|uniprotkb:GAN(gene name)|psi-mi:GAN(display_short)|uniprotkb:GAN1(gene name synonym)|uniprotkb:KLHL16(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Ding et al. (2002)	pubmed:12147674|mint:MINT-5215601	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-764620	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005900.2|dip:DIP-33474N|ensembl:ENSG00000131711(gene)|ensembl:ENST00000296755(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001764"(neuron migration)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016358"(dendrite development)|go:"GO:0021700"(developmental maturation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0017085"(response to insecticide)|go:"GO:0045202"(synapse)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR027321|mint:P46821|interpro:IPR026074	refseq:NP_071324.1|ensembl:ENSG00000261609(gene)|ensembl:ENST00000648994(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030579|mint:Q9H2C0|rcsb pdb:2PPI|rcsb pdb:3HVE|reactome:R-HSA-8951664|reactome:R-HSA-983168	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2003/07/30	2014/10/16	rogid:uSRzrWaYU/dmkItUkCK4zex+/TM9606	rogid:dpwb1OLDaSeParbSZnR8pjveyLk9606	intact-crc:2F1585577B2CCDBF|rigid:4o0k59YCnBR+cXtGXk3JCNKGssM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46821	uniprotkb:Q9H2C0	intact:EBI-764611|uniprotkb:A2BDK5|ensembl:ENSP00000296755	intact:EBI-764342|ensembl:ENSP00000497351	psi-mi:map1b_human(display_long)|uniprotkb:MAP1B(gene name)|psi-mi:MAP1B(display_short)	psi-mi:gan_human(display_long)|uniprotkb:Kelch-like protein 16(gene name synonym)|uniprotkb:GAN(gene name)|psi-mi:GAN(display_short)|uniprotkb:GAN1(gene name synonym)|uniprotkb:KLHL16(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Ding et al. (2002)	pubmed:12147674|mint:MINT-5215601	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-764628	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005900.2|dip:DIP-33474N|ensembl:ENSG00000131711(gene)|ensembl:ENST00000296755(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001764"(neuron migration)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016358"(dendrite development)|go:"GO:0021700"(developmental maturation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0017085"(response to insecticide)|go:"GO:0045202"(synapse)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR027321|mint:P46821|interpro:IPR026074	refseq:NP_071324.1|ensembl:ENSG00000261609(gene)|ensembl:ENST00000648994(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030579|mint:Q9H2C0|rcsb pdb:2PPI|rcsb pdb:3HVE|reactome:R-HSA-8951664|reactome:R-HSA-983168	-	-	-	comment:Gigaxonin protein colocalized with MAP1B-LC along  the microtubule network of transfected COS-7 cells|comment:It was noted that in cells cotransfected with MAP1B-LC and gigaxonin ;  gigaxonin increased the ability of MAP1B-LC to render the endogenous microtubule network resistant to microtubule-destabilizing reagents.|caution:"The COOH kelch repeat domain of gigaxonin (Gig-C) coaligned with  MAP1B-LC in cotransfected cells. Note coordinates of regions used in study not given in report of Ding et al."	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2003/07/30	2014/10/16	rogid:uSRzrWaYU/dmkItUkCK4zex+/TM9606	rogid:dpwb1OLDaSeParbSZnR8pjveyLk9606	intact-crc:2E2022B9FAE0C835|rigid:4o0k59YCnBR+cXtGXk3JCNKGssM	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H2C0	uniprotkb:P46821	intact:EBI-764342|ensembl:ENSP00000497351	intact:EBI-764611|uniprotkb:A2BDK5|ensembl:ENSP00000296755	psi-mi:gan_human(display_long)|uniprotkb:Kelch-like protein 16(gene name synonym)|uniprotkb:GAN(gene name)|psi-mi:GAN(display_short)|uniprotkb:GAN1(gene name synonym)|uniprotkb:KLHL16(gene name synonym)	psi-mi:map1b_human(display_long)|uniprotkb:MAP1B(gene name)|psi-mi:MAP1B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ding et al. (2002)	pubmed:12147674|mint:MINT-5215601	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-764641	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071324.1|ensembl:ENSG00000261609(gene)|ensembl:ENST00000648994(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030579|mint:Q9H2C0|rcsb pdb:2PPI|rcsb pdb:3HVE|reactome:R-HSA-8951664|reactome:R-HSA-983168	refseq:NP_005900.2|dip:DIP-33474N|ensembl:ENSG00000131711(gene)|ensembl:ENST00000296755(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001764"(neuron migration)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016358"(dendrite development)|go:"GO:0021700"(developmental maturation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0017085"(response to insecticide)|go:"GO:0045202"(synapse)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR027321|mint:P46821|interpro:IPR026074	-	-	-	-	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2003/07/30	2014/10/16	rogid:dpwb1OLDaSeParbSZnR8pjveyLk9606	rogid:uSRzrWaYU/dmkItUkCK4zex+/TM9606	intact-crc:EE0C8A663B51DFFE|rigid:4o0k59YCnBR+cXtGXk3JCNKGssM	false	ha tag:n-n	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8CA72	uniprotkb:P14873	intact:EBI-764672|ensembl:ENSMUSP00000070168	intact:EBI-764653|uniprotkb:E9QM11|ensembl:ENSMUSP00000068374	psi-mi:gan_mouse(display_long)|uniprotkb:Gan(gene name)|psi-mi:Gan(display_short)	psi-mi:map1b_mouse(display_long)|uniprotkb:MAP1.2(gene name synonym)|uniprotkb:"MAP1(X)"(gene name synonym)|uniprotkb:Map1b(gene name)|psi-mi:Map1b(display_short)|uniprotkb:Mtap1b(gene name synonym)|uniprotkb:Mtap5(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Ding et al. (2002)	pubmed:12147674|mint:MINT-5215601	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-764667	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074620.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030579|reactome:R-MMU-8951664|reactome:R-MMU-983168|ensembl:ENSMUST00000064488(transcript)|ensembl:ENSMUSG00000052557(gene)	refseq:NP_032660.2|ensembl:ENSMUSG00000052727(gene)|ensembl:ENSMUST00000064762(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003779"(actin binding)|go:"GO:0005519"(cytoskeletal regulatory protein binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0008017"(microtubule binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017085"(response to insecticide)|go:"GO:0021700"(developmental maturation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0016358"(dendrite development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|interpro:IPR026074|interpro:IPR027321|mint:P14873	-	-	-	comment:Q8CA72 identified as the mouse ortholog to Human Gigaxonin by curator.	taxid:10090(mouse-neuron)|taxid:10090(Mus musculus neuronal cell)	-	2003/07/30	2014/10/16	rogid:RbjoXvNfdibfAAi67ZdOAU/k2+M10090	rogid:8Ph5u01KvXbfedKGBXu5cGckp7Y10090	intact-crc:FB2E42266C661E9B|rigid:r/SzLRGtPCKv6rJfQRz9OUd1Sc8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)