#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P54274-2	uniprotkb:Q15691	intact:EBI-711018|ensembl:ENSP00000276602	intact:EBI-1004115|uniprotkb:Q3KQS8|uniprotkb:B2R6I7|uniprotkb:E1P5M8|ensembl:ENSP00000364721	psi-mi:p54274-2(display_long)|uniprotkb:TERF1(gene name)|psi-mi:TERF1(display_short)|uniprotkb:PIN2(gene name synonym)|uniprotkb:TRBF1(gene name synonym)|uniprotkb:TRF(gene name synonym)|uniprotkb:TRF1(gene name synonym)|uniprotkb:NIMA-interacting protein 2(gene name synonym)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym)|uniprotkb:Telomeric protein Pin2/TRF1(gene name synonym)|uniprotkb:Pin2(isoform synonym)	psi-mi:mare1_human(display_long)|uniprotkb:APC-binding protein EB1(gene name synonym)|uniprotkb:End-binding protein 1(gene name synonym)|uniprotkb:MAPRE1(gene name)|psi-mi:MAPRE1(display_short)	psi-mi:"MI:0096"(pull down)	Nakamura et al. (2002)	pubmed:11943150|mint:MINT-5215262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-1004126	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-710997(terf1_human)|ensembl:ENSG00000147601(gene)|ensembl:ENST00000276602(transcript)|uniprotkb:P54274-2(isoform-parent)	refseq:NP_036457.1|refseq:XP_011526998.1|ensembl:ENSG00000101367(gene)|ensembl:ENST00000375571(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0016477"(cell migration)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027739|interpro:IPR036133|interpro:IPR036872|mint:Q15691|rcsb pdb:1PA7|rcsb pdb:1TXQ|rcsb pdb:1UEG|rcsb pdb:1VKA|rcsb pdb:1WU9|rcsb pdb:1YIB|rcsb pdb:1YIG|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2QJZ|rcsb pdb:2R8U|rcsb pdb:3GJO|rcsb pdb:3MTU|rcsb pdb:3MUD|rcsb pdb:3TQ7|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA6|rcsb pdb:5JV3|rcsb pdb:5JVM|rcsb pdb:5JVP|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:5JX1|rcsb pdb:5WLQ|rcsb pdb:6PF2|rcsb pdb:6PFP|rcsb pdb:6YF5|rcsb pdb:6YSH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|dip:DIP-38018N	-	-	-	figure legend:1a|expression level:[35S]Pin2 was generated by in vitro transcription and translation|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/04/30	2014/10/16	rogid:hX5owgLwr/JCK2JJ+khossLxtYA9606	rogid:+JBCBM7dbbrxn6mX8RiwejYWJ2U9606	intact-crc:8340FDBA2B0C455C|rigid:rH9j4MfPRhIEiKColJ4DF4JWvIM	false	35s radiolabel:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P25054	uniprotkb:Q15691	intact:EBI-727707|uniprotkb:Q15162|uniprotkb:Q15163|uniprotkb:Q93042|uniprotkb:D3DT03|uniprotkb:B7Z2B6|ensembl:ENSP00000257430|ensembl:ENSP00000427089	intact:EBI-1004115|uniprotkb:Q3KQS8|uniprotkb:B2R6I7|uniprotkb:E1P5M8|ensembl:ENSP00000364721	psi-mi:apc_human(display_long)|uniprotkb:APC(gene name)|psi-mi:APC(display_short)|uniprotkb:DP2.5(gene name synonym)|uniprotkb:Deleted in polyposis 2.5(gene name synonym)	psi-mi:mare1_human(display_long)|uniprotkb:APC-binding protein EB1(gene name synonym)|uniprotkb:End-binding protein 1(gene name synonym)|uniprotkb:MAPRE1(gene name)|psi-mi:MAPRE1(display_short)	psi-mi:"MI:0096"(pull down)	Nakamura et al. (2002)	pubmed:11943150|mint:MINT-5215262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-1004194	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000029.2|refseq:NP_001120982.1|dip:DIP-33556N|refseq:NP_001120983.2|ensembl:ENSG00000134982(gene)|ensembl:ENST00000257430(transcript)|ensembl:ENST00000508376(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007155"(cell adhesion)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000225(Armadillo)|interpro:IPR009223(APC cysteine-rich)|interpro:IPR009224(SAMP)|interpro:IPR009232(EB-1 binding)|interpro:IPR009234(APC basic)|interpro:IPR009240(APC 15 residue)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818|interpro:IPR026831|interpro:IPR026836|interpro:IPR032038|interpro:IPR036149|interpro:IPR041257|mint:P25054|rcsb pdb:1DEB|rcsb pdb:1EMU|rcsb pdb:1JPP|rcsb pdb:1M5I|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:1V18|rcsb pdb:2RQU|rcsb pdb:3AU3|rcsb pdb:3NMW|rcsb pdb:3NMX|rcsb pdb:3NMZ|rcsb pdb:3QHE|rcsb pdb:3RL7|rcsb pdb:3RL8|rcsb pdb:3T7U|rcsb pdb:4G69|rcsb pdb:4YJE|rcsb pdb:4YJL|rcsb pdb:4YK6|rcsb pdb:5B6G|rcsb pdb:5IZ6|rcsb pdb:5IZ8|rcsb pdb:5IZ9|rcsb pdb:5IZA|rcsb pdb:5Z8H|reactome:R-HSA-111465|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-3769402|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467333|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5689896	refseq:NP_036457.1|refseq:XP_011526998.1|ensembl:ENSG00000101367(gene)|ensembl:ENST00000375571(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0016477"(cell migration)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027739|interpro:IPR036133|interpro:IPR036872|mint:Q15691|rcsb pdb:1PA7|rcsb pdb:1TXQ|rcsb pdb:1UEG|rcsb pdb:1VKA|rcsb pdb:1WU9|rcsb pdb:1YIB|rcsb pdb:1YIG|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2QJZ|rcsb pdb:2R8U|rcsb pdb:3GJO|rcsb pdb:3MTU|rcsb pdb:3MUD|rcsb pdb:3TQ7|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA6|rcsb pdb:5JV3|rcsb pdb:5JVM|rcsb pdb:5JVP|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:5JX1|rcsb pdb:5WLQ|rcsb pdb:6PF2|rcsb pdb:6PFP|rcsb pdb:6YF5|rcsb pdb:6YSH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|dip:DIP-38018N	-	-	-	figure legend:1b|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells)	-	2003/04/30	2014/10/16	rogid:BLZJqb4+lTr7gs2vgkXMvuwG+KU9606	rogid:+JBCBM7dbbrxn6mX8RiwejYWJ2U9606	intact-crc:40FB7BFA5FB065AB|rigid:SEl1ZMAOGv59acavDF4G3NjbDcw	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P54274	uniprotkb:Q15691	intact:EBI-710997|uniprotkb:A7XP29|uniprotkb:Q15553|uniprotkb:Q93029|ensembl:ENSP00000276603|uniprotkb:Q8NHT6	intact:EBI-1004115|uniprotkb:Q3KQS8|uniprotkb:B2R6I7|uniprotkb:E1P5M8|ensembl:ENSP00000364721	psi-mi:terf1_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym)|uniprotkb:NIMA-interacting protein 2(gene name synonym)|uniprotkb:Telomeric protein Pin2/TRF1(gene name synonym)|uniprotkb:TERF1(gene name)|psi-mi:TERF1(display_short)|uniprotkb:PIN2(gene name synonym)|uniprotkb:TRF(gene name synonym)|uniprotkb:TRF1(gene name synonym)|uniprotkb:TRBF1(gene name synonym)	psi-mi:mare1_human(display_long)|uniprotkb:APC-binding protein EB1(gene name synonym)|uniprotkb:End-binding protein 1(gene name synonym)|uniprotkb:MAPRE1(gene name)|psi-mi:MAPRE1(display_short)	psi-mi:"MI:0096"(pull down)	Nakamura et al. (2002)	pubmed:11943150|mint:MINT-5215262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-1004214	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003209.2|refseq:NP_059523.2|ensembl:ENSG00000147601(gene)|go:"GO:0051301"(cell division)|go:"GO:0051974"(negative regulation of telomerase activity)|ensembl:ENST00000276603(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P54274|rcsb pdb:1BA5|rcsb pdb:1H6O|rcsb pdb:1ITY|rcsb pdb:1IV6|rcsb pdb:1W0T|rcsb pdb:3BQO|rcsb pdb:3L82|rcsb pdb:5HKP|rcsb pdb:5WIR|rcsb pdb:5XUP|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0090656"(t-circle formation)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1904914"(negative regulation of establishment of protein-containing complex localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|dip:DIP-29412N	refseq:NP_036457.1|refseq:XP_011526998.1|ensembl:ENSG00000101367(gene)|ensembl:ENST00000375571(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0016477"(cell migration)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027739|interpro:IPR036133|interpro:IPR036872|mint:Q15691|rcsb pdb:1PA7|rcsb pdb:1TXQ|rcsb pdb:1UEG|rcsb pdb:1VKA|rcsb pdb:1WU9|rcsb pdb:1YIB|rcsb pdb:1YIG|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2QJZ|rcsb pdb:2R8U|rcsb pdb:3GJO|rcsb pdb:3MTU|rcsb pdb:3MUD|rcsb pdb:3TQ7|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA6|rcsb pdb:5JV3|rcsb pdb:5JVM|rcsb pdb:5JVP|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:5JX1|rcsb pdb:5WLQ|rcsb pdb:6PF2|rcsb pdb:6PFP|rcsb pdb:6YF5|rcsb pdb:6YSH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|dip:DIP-38018N	-	-	-	figure legend:1b|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells)	-	2003/04/30	2014/10/16	rogid:3Tjmp8hqEhLBIQqxxWHntpL4hz49606	rogid:+JBCBM7dbbrxn6mX8RiwejYWJ2U9606	intact-crc:F2754F20A55905AE|rigid:fsoZXhzRDMl6+TzRa6RA3mpMAqg	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15691	uniprotkb:P54274	intact:EBI-1004115|uniprotkb:Q3KQS8|uniprotkb:B2R6I7|uniprotkb:E1P5M8|ensembl:ENSP00000364721	intact:EBI-710997|uniprotkb:A7XP29|uniprotkb:Q15553|uniprotkb:Q93029|ensembl:ENSP00000276603|uniprotkb:Q8NHT6	psi-mi:mare1_human(display_long)|uniprotkb:APC-binding protein EB1(gene name synonym)|uniprotkb:End-binding protein 1(gene name synonym)|uniprotkb:MAPRE1(gene name)|psi-mi:MAPRE1(display_short)	psi-mi:terf1_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym)|uniprotkb:NIMA-interacting protein 2(gene name synonym)|uniprotkb:Telomeric protein Pin2/TRF1(gene name synonym)|uniprotkb:TERF1(gene name)|psi-mi:TERF1(display_short)|uniprotkb:PIN2(gene name synonym)|uniprotkb:TRF(gene name synonym)|uniprotkb:TRF1(gene name synonym)|uniprotkb:TRBF1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nakamura et al. (2002)	pubmed:11943150|mint:MINT-5215262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-1004274	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036457.1|refseq:XP_011526998.1|ensembl:ENSG00000101367(gene)|ensembl:ENST00000375571(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0016477"(cell migration)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027739|interpro:IPR036133|interpro:IPR036872|mint:Q15691|rcsb pdb:1PA7|rcsb pdb:1TXQ|rcsb pdb:1UEG|rcsb pdb:1VKA|rcsb pdb:1WU9|rcsb pdb:1YIB|rcsb pdb:1YIG|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2QJZ|rcsb pdb:2R8U|rcsb pdb:3GJO|rcsb pdb:3MTU|rcsb pdb:3MUD|rcsb pdb:3TQ7|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA6|rcsb pdb:5JV3|rcsb pdb:5JVM|rcsb pdb:5JVP|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:5JX1|rcsb pdb:5WLQ|rcsb pdb:6PF2|rcsb pdb:6PFP|rcsb pdb:6YF5|rcsb pdb:6YSH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|dip:DIP-38018N	refseq:NP_003209.2|refseq:NP_059523.2|ensembl:ENSG00000147601(gene)|go:"GO:0051301"(cell division)|go:"GO:0051974"(negative regulation of telomerase activity)|ensembl:ENST00000276603(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P54274|rcsb pdb:1BA5|rcsb pdb:1H6O|rcsb pdb:1ITY|rcsb pdb:1IV6|rcsb pdb:1W0T|rcsb pdb:3BQO|rcsb pdb:3L82|rcsb pdb:5HKP|rcsb pdb:5WIR|rcsb pdb:5XUP|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0090656"(t-circle formation)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1904914"(negative regulation of establishment of protein-containing complex localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|dip:DIP-29412N	-	-	-	figure legend:1c|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2003/04/30	2014/10/16	rogid:+JBCBM7dbbrxn6mX8RiwejYWJ2U9606	rogid:3Tjmp8hqEhLBIQqxxWHntpL4hz49606	intact-crc:04D9FD9A3B16E18A|rigid:fsoZXhzRDMl6+TzRa6RA3mpMAqg	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15691	uniprotkb:P54274-2	intact:EBI-1004115|uniprotkb:Q3KQS8|uniprotkb:B2R6I7|uniprotkb:E1P5M8|ensembl:ENSP00000364721	intact:EBI-711018|ensembl:ENSP00000276602	psi-mi:mare1_human(display_long)|uniprotkb:APC-binding protein EB1(gene name synonym)|uniprotkb:End-binding protein 1(gene name synonym)|uniprotkb:MAPRE1(gene name)|psi-mi:MAPRE1(display_short)	psi-mi:p54274-2(display_long)|uniprotkb:TERF1(gene name)|psi-mi:TERF1(display_short)|uniprotkb:PIN2(gene name synonym)|uniprotkb:TRBF1(gene name synonym)|uniprotkb:TRF(gene name synonym)|uniprotkb:TRF1(gene name synonym)|uniprotkb:NIMA-interacting protein 2(gene name synonym)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym)|uniprotkb:Telomeric protein Pin2/TRF1(gene name synonym)|uniprotkb:Pin2(isoform synonym)	psi-mi:"MI:0663"(confocal microscopy)	Nakamura et al. (2002)	pubmed:11943150|mint:MINT-5215262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-1004354	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036457.1|refseq:XP_011526998.1|ensembl:ENSG00000101367(gene)|ensembl:ENST00000375571(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0016477"(cell migration)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027739|interpro:IPR036133|interpro:IPR036872|mint:Q15691|rcsb pdb:1PA7|rcsb pdb:1TXQ|rcsb pdb:1UEG|rcsb pdb:1VKA|rcsb pdb:1WU9|rcsb pdb:1YIB|rcsb pdb:1YIG|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2QJZ|rcsb pdb:2R8U|rcsb pdb:3GJO|rcsb pdb:3MTU|rcsb pdb:3MUD|rcsb pdb:3TQ7|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA6|rcsb pdb:5JV3|rcsb pdb:5JVM|rcsb pdb:5JVP|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:5JX1|rcsb pdb:5WLQ|rcsb pdb:6PF2|rcsb pdb:6PFP|rcsb pdb:6YF5|rcsb pdb:6YSH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|dip:DIP-38018N	intact:EBI-710997(terf1_human)|ensembl:ENSG00000147601(gene)|ensembl:ENST00000276602(transcript)|uniprotkb:P54274-2(isoform-parent)	-	-	-	figure legend:2|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2003/04/30	2014/10/16	rogid:+JBCBM7dbbrxn6mX8RiwejYWJ2U9606	rogid:hX5owgLwr/JCK2JJ+khossLxtYA9606	intact-crc:5DDE63287C1C7DB4|rigid:rH9j4MfPRhIEiKColJ4DF4JWvIM	false	red fluorescent protein tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)