#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P14599	uniprotkb:Q9W0K0	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	intact:EBI-74120|uniprotkb:Q9NH69|uniprotkb:Q8IGG5|ensemblmetazoa:FBpp0072523	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:jip1_drome(display_long)|uniprotkb:Protein eye developmental SP512(gene name synonym)|uniprotkb:APP-like-interacting protein 1(gene name synonym)|uniprotkb:Aplip1(gene name)|psi-mi:Aplip1(display_short)|uniprotkb:SP512(gene name synonym)|uniprotkb:CG1200(orf name)	psi-mi:"MI:0018"(two hybrid)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-74150	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	refseq:NP_728573.1|refseq:NP_728574.1|flybase:FBgn0040281|dip:DIP-20311N|ensemblmetazoa:FBgn0040281(gene)|ensemblmetazoa:FBtr0072627(transcript)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0019894"(kinesin binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048491"(retrograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|rcsb pdb:4Z88	-	-	-	dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2003/11/03	2014/10/16	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	rogid:fOLEqOpPaBndqMQqgReljn1SA+I7227	intact-crc:57785841A53926B0|rigid:Oacz3d8BVemMAGO0g4NTiusy1Qg	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9VX41	uniprotkb:P14599	intact:EBI-74153|uniprotkb:Q960Z2|ensemblmetazoa:FBpp0074225	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	psi-mi:q9vx41_drome(display_long)|uniprotkb:X11L(gene name)|psi-mi:X11L(display_short)|uniprotkb:Mint(gene name synonym)|uniprotkb:CG5678(gene name synonym)|uniprotkb:Dmel\CG5675(gene name synonym)|uniprotkb:Dmint(gene name synonym)|uniprotkb:Dmint1(gene name synonym)|uniprotkb:MINT(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:X11-like(gene name synonym)|uniprotkb:X11Lalpha(gene name synonym)|uniprotkb:dX11(gene name synonym)|uniprotkb:dX11L(gene name synonym)|uniprotkb:dX11Lalpha(gene name synonym)|uniprotkb:x11(gene name synonym)|uniprotkb:x11Lalpha(gene name synonym)|uniprotkb:Dmel_CG5675(orf name)|uniprotkb:CG5675(orf name)	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:"MI:0018"(two hybrid)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-74168	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_573224.2|flybase:FBgn0026313|dip:DIP-20815N|ensemblmetazoa:FBgn0026313(gene)|ensemblmetazoa:FBtr0074451(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0043197"(dendritic spine)|go:"GO:0048749"(compound eye development)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098793"(presynapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	-	-	-	dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2003/11/03	2014/10/16	rogid:naV23VxHMWR+MDwcH91M2sI/NlU7227	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	intact-crc:B3C973B05F06919C|rigid:hkbrfJX0O5+2/xGdp8irCqNEyYo	false	-	sufficient binding region:835..835-887	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14599	uniprotkb:Q9VWQ2	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	intact:EBI-74173|intact:EBI-120844|uniprotkb:B9EQU9|uniprotkb:M9NEP2|uniprotkb:M9NFD4|uniprotkb:O96630|ensemblmetazoa:FBpp0074405	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:s6kl_drome(display_long)|uniprotkb:S6KL(gene name)|psi-mi:S6KL(display_short)|uniprotkb:Bin4(gene name synonym)|uniprotkb:Pk17E(gene name synonym)|uniprotkb:Protein kinase-like 17E(gene name synonym)|uniprotkb:S6 kinase-like protein(gene name synonym)|uniprotkb:CG7001(orf name)	psi-mi:"MI:0018"(two hybrid)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-74185	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	refseq:NP_524861.2|flybase:FBgn0283473|refseq:NP_001245742.1|refseq:NP_001245743.1|ensemblmetazoa:FBgn0283473(gene)|ensemblmetazoa:FBtr0074634(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|reactome:R-DME-166208	-	-	-	dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2003/11/03	2015/11/09	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	rogid:xtOpsz6rGDHkPwwHcafizK7VO2k7227	intact-crc:95A5826CF0E6F65D|rigid:sQS7BYR2wPdgigfoNoHrUxWQhVM	false	sufficient binding region:?-?	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9W0K0	uniprotkb:P14599	intact:EBI-74120|uniprotkb:Q9NH69|uniprotkb:Q8IGG5|ensemblmetazoa:FBpp0072523	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	psi-mi:jip1_drome(display_long)|uniprotkb:Protein eye developmental SP512(gene name synonym)|uniprotkb:APP-like-interacting protein 1(gene name synonym)|uniprotkb:Aplip1(gene name)|psi-mi:Aplip1(display_short)|uniprotkb:SP512(gene name synonym)|uniprotkb:CG1200(orf name)	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:"MI:0018"(two hybrid)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-77445	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_728573.1|refseq:NP_728574.1|flybase:FBgn0040281|dip:DIP-20311N|ensemblmetazoa:FBgn0040281(gene)|ensemblmetazoa:FBtr0072627(transcript)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0019894"(kinesin binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048491"(retrograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|rcsb pdb:4Z88	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	-	-	-	dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2003/11/03	2014/10/16	rogid:fOLEqOpPaBndqMQqgReljn1SA+I7227	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	intact-crc:E6E9E4454ABB045C|rigid:Oacz3d8BVemMAGO0g4NTiusy1Qg	false	necessary binding region:331-490(IPR006020)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9W0K0	uniprotkb:P14599	intact:EBI-74120|uniprotkb:Q9NH69|uniprotkb:Q8IGG5|ensemblmetazoa:FBpp0072523	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	psi-mi:jip1_drome(display_long)|uniprotkb:Protein eye developmental SP512(gene name synonym)|uniprotkb:APP-like-interacting protein 1(gene name synonym)|uniprotkb:Aplip1(gene name)|psi-mi:Aplip1(display_short)|uniprotkb:SP512(gene name synonym)|uniprotkb:CG1200(orf name)	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:"MI:0018"(two hybrid)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-77449	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_728573.1|refseq:NP_728574.1|flybase:FBgn0040281|dip:DIP-20311N|ensemblmetazoa:FBgn0040281(gene)|ensemblmetazoa:FBtr0072627(transcript)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0019894"(kinesin binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048491"(retrograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|rcsb pdb:4Z88	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	pubmed:10610414(see-also)	-	-	dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2003/11/03	2014/10/16	rogid:fOLEqOpPaBndqMQqgReljn1SA+I7227	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	intact-crc:CA1D2AD305DD53E2|rigid:Oacz3d8BVemMAGO0g4NTiusy1Qg	false	-	necessary binding region:874-883	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14599	uniprotkb:Q9W0K0	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	intact:EBI-74120|uniprotkb:Q9NH69|uniprotkb:Q8IGG5|ensemblmetazoa:FBpp0072523	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:jip1_drome(display_long)|uniprotkb:Protein eye developmental SP512(gene name synonym)|uniprotkb:APP-like-interacting protein 1(gene name synonym)|uniprotkb:Aplip1(gene name)|psi-mi:Aplip1(display_short)|uniprotkb:SP512(gene name synonym)|uniprotkb:CG1200(orf name)	psi-mi:"MI:0096"(pull down)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-74192	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	refseq:NP_728573.1|refseq:NP_728574.1|flybase:FBgn0040281|dip:DIP-20311N|ensemblmetazoa:FBgn0040281(gene)|ensemblmetazoa:FBtr0072627(transcript)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0019894"(kinesin binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048491"(retrograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|rcsb pdb:4Z88	-	-	-	comment:APLIP1 was expressed as GST fused protein|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/11/03	2014/10/16	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	rogid:fOLEqOpPaBndqMQqgReljn1SA+I7227	intact-crc:C7D516AF522EDD6E|rigid:Oacz3d8BVemMAGO0g4NTiusy1Qg	false	glutathione s tranferase tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P92208	uniprotkb:Q23977	intact:EBI-74487|uniprotkb:O01366|uniprotkb:Q94542|ensemblmetazoa:FBpp0079676|ensemblmetazoa:FBpp0290204|ensemblmetazoa:FBpp0291573	intact:EBI-74214|uniprotkb:O18411|uniprotkb:Q8SZ04|uniprotkb:Q8SZZ1|uniprotkb:Q9I7S3|ensemblmetazoa:FBpp0073578	psi-mi:jnk_drome(display_long)|uniprotkb:bsk(gene name)|psi-mi:bsk(display_short)|uniprotkb:JNK(gene name synonym)|uniprotkb:CG5680(orf name)|uniprotkb:Protein basket(gene name synonym)	psi-mi:hep_drome(display_long)|uniprotkb:hep(gene name)|psi-mi:hep(display_short)|uniprotkb:hem(gene name synonym)|uniprotkb:MKK7(gene name synonym)|uniprotkb:CG4353(orf name)	psi-mi:"MI:0096"(pull down)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-74510	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046844"(chorion micropyle formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0048666"(neuron development)|go:"GO:0048674"(collateral sprouting of injured axon)|go:"GO:0048675"(axon extension)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904801"(positive regulation of neuron remodeling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:5AWM|reactome:R-DME-193648|reactome:R-DME-209397|reactome:R-DME-209409|reactome:R-DME-209425|reactome:R-DME-209459|reactome:R-DME-2559580|reactome:R-DME-2871796|reactome:R-DME-376172|reactome:R-DME-450321|reactome:R-DME-450341|reactome:R-DME-9007892|refseq:NP_001162930.1|refseq:NP_001162932.1|refseq:NP_723541.1|flybase:FBgn0000229|dip:DIP-17307N|ensemblmetazoa:FBgn0000229(gene)|ensemblmetazoa:FBtr0080087(transcript)|ensemblmetazoa:FBtr0300982(transcript)|ensemblmetazoa:FBtr0302378(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007616"(long-term memory)|go:"GO:0009408"(response to heat)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016319"(mushroom body development)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035006"(melanization defense response)|go:"GO:0035313"(wound healing, spreading of epidermal cells)	refseq:NP_727661.1|flybase:FBgn0010303|refseq:NP_511142.2|refseq:NP_001259501.1|dip:DIP-30870N|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-209397|reactome:R-DME-209447|reactome:R-DME-350376|go:"GO:0042060"(wound healing)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046528"(imaginal disc fusion)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046844"(chorion micropyle formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0048675"(axon extension)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903688"(positive regulation of border follicle cell migration)|ensemblmetazoa:FBgn0010303(gene)|ensemblmetazoa:FBtr0073747(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007254"(JNK cascade)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007561"(imaginal disc eversion)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008545"(JUN kinase kinase activity)|go:"GO:0009408"(response to heat)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030424"(axon)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0034769"(basement membrane disassembly)|go:"GO:0035006"(melanization defense response)|go:"GO:0036335"(intestinal stem cell homeostasis)	-	-	-	comment:GST fused DJNK and FLAG tagged hep were used.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/11/03	2014/10/16	rogid:o81/FEGIpdc5K06yBAQusZL6seI7227	rogid:XTLY74pOC/Mk9P0Rrq5DSUM+K0w7227	intact-crc:4A73EB11DF0ED352|rigid:p6EnhRcLM6PNWHXsT81jeqFQj3Q	false	glutathione s tranferase tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q9WVI9	uniprotkb:P92208	intact:EBI-74515|ensembl:ENSMUSP00000050773|uniprotkb:O35145|uniprotkb:Q925J8|uniprotkb:Q9R1H9|uniprotkb:Q9R1Z1|uniprotkb:Q9WVI7|uniprotkb:Q9WVI8	intact:EBI-74487|uniprotkb:O01366|uniprotkb:Q94542|ensemblmetazoa:FBpp0079676|ensemblmetazoa:FBpp0290204|ensemblmetazoa:FBpp0291573	psi-mi:jip1_mouse(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Prkm8ip(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)	psi-mi:jnk_drome(display_long)|uniprotkb:bsk(gene name)|psi-mi:bsk(display_short)|uniprotkb:JNK(gene name synonym)|uniprotkb:CG5680(orf name)|uniprotkb:Protein basket(gene name synonym)	psi-mi:"MI:0096"(pull down)	Taru et al. (2002)	pubmed:11912189	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-74543	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007165"(signal transduction)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0044302"(dentate gyrus mossy fiber)|go:"GO:0045202"(synapse)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2000564"(regulation of CD8-positive, alpha-beta T cell proliferation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035638|interpro:IPR036028|rcsb pdb:1UKH|rcsb pdb:1UKI|rcsb pdb:3O17|rcsb pdb:3O2M|rcsb pdb:3V3V|rcsb pdb:6F5E|go:"GO:0005078"(MAP-kinase scaffold activity)|ensembl:ENSMUST00000050312(transcript)|ensembl:ENSMUSG00000027223(gene)|refseq:NP_035292.2	go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046844"(chorion micropyle formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0048666"(neuron development)|go:"GO:0048674"(collateral sprouting of injured axon)|go:"GO:0048675"(axon extension)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904801"(positive regulation of neuron remodeling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:5AWM|reactome:R-DME-193648|reactome:R-DME-209397|reactome:R-DME-209409|reactome:R-DME-209425|reactome:R-DME-209459|reactome:R-DME-2559580|reactome:R-DME-2871796|reactome:R-DME-376172|reactome:R-DME-450321|reactome:R-DME-450341|reactome:R-DME-9007892|refseq:NP_001162930.1|refseq:NP_001162932.1|refseq:NP_723541.1|flybase:FBgn0000229|dip:DIP-17307N|ensemblmetazoa:FBgn0000229(gene)|ensemblmetazoa:FBtr0080087(transcript)|ensemblmetazoa:FBtr0300982(transcript)|ensemblmetazoa:FBtr0302378(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007616"(long-term memory)|go:"GO:0009408"(response to heat)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016319"(mushroom body development)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035006"(melanization defense response)|go:"GO:0035313"(wound healing, spreading of epidermal cells)	-	-	-	comment:GST tagged DJNK used.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/11/03	2014/10/16	rogid:r8Xy/vpp0kYLCZ7vw1sE666dk/g10090	rogid:o81/FEGIpdc5K06yBAQusZL6seI7227	intact-crc:03321F6AFB2ACDD3|rigid:6mLR9Ui2/EkeSIiRSOWW6aE7Ez0	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P14599	uniprotkb:Q9WVI9	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	intact:EBI-74515|ensembl:ENSMUSP00000050773|uniprotkb:O35145|uniprotkb:Q925J8|uniprotkb:Q9R1H9|uniprotkb:Q9R1Z1|uniprotkb:Q9WVI7|uniprotkb:Q9WVI8	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:jip1_mouse(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Prkm8ip(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-77506	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007165"(signal transduction)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0044302"(dentate gyrus mossy fiber)|go:"GO:0045202"(synapse)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2000564"(regulation of CD8-positive, alpha-beta T cell proliferation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035638|interpro:IPR036028|rcsb pdb:1UKH|rcsb pdb:1UKI|rcsb pdb:3O17|rcsb pdb:3O2M|rcsb pdb:3V3V|rcsb pdb:6F5E|go:"GO:0005078"(MAP-kinase scaffold activity)|ensembl:ENSMUST00000050312(transcript)|ensembl:ENSMUSG00000027223(gene)|refseq:NP_035292.2	-	-	-	dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/11/03	2014/10/16	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	rogid:r8Xy/vpp0kYLCZ7vw1sE666dk/g10090	intact-crc:C5844D736D66ED3B|rigid:Fpybsrxae5bolqrd2EtOfImMIPU	false	glutathione s tranferase tag:?-?|binding-associated region:?-?	ha tag:?-?	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P14599	uniprotkb:Q9ERE9	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	intact:EBI-74576|ensembl:ENSMUSP00000023291|uniprotkb:Q9CXI4	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:jip2_mouse(display_long)|uniprotkb:Mapk8ip2(gene name)|psi-mi:Mapk8ip2(display_short)|uniprotkb:Ib2(gene name synonym)|uniprotkb:Jip2(gene name synonym)|uniprotkb:Islet-brain-2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-77511	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	ensembl:ENSMUSG00000022619(gene)|ensembl:ENSMUST00000023291(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0035176"(social behavior)|go:"GO:0007617"(mating behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046958"(nonassociative learning)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0014069"(postsynaptic density)|interpro:IPR001452(Src homology-3)|go:"GO:0019894"(kinesin binding)|interpro:IPR006020(Phosphotyrosine interaction region)|go:"GO:0019901"(protein kinase binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035637|mint:Q9ERE9|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|refseq:NP_068740.3	-	-	-	dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/11/03	2014/10/16	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	rogid:NUVswDC52pSAuf8BL8b9wqVc8ng10090	intact-crc:C90E3474FE12166F|rigid:/tECgNwD3NcHku7kqnPLbrHB9Mw	false	glutathione s tranferase tag:?-?|binding-associated region:?-?	ha tag:?-?	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P14599	uniprotkb:Q9VX41	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	intact:EBI-74153|uniprotkb:Q960Z2|ensemblmetazoa:FBpp0074225	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:q9vx41_drome(display_long)|uniprotkb:X11L(gene name)|psi-mi:X11L(display_short)|uniprotkb:Mint(gene name synonym)|uniprotkb:CG5678(gene name synonym)|uniprotkb:Dmel\CG5675(gene name synonym)|uniprotkb:Dmint(gene name synonym)|uniprotkb:Dmint1(gene name synonym)|uniprotkb:MINT(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:X11-like(gene name synonym)|uniprotkb:X11Lalpha(gene name synonym)|uniprotkb:dX11(gene name synonym)|uniprotkb:dX11L(gene name synonym)|uniprotkb:dX11Lalpha(gene name synonym)|uniprotkb:x11(gene name synonym)|uniprotkb:x11Lalpha(gene name synonym)|uniprotkb:Dmel_CG5675(orf name)|uniprotkb:CG5675(orf name)	psi-mi:"MI:0096"(pull down)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-77516	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	refseq:NP_573224.2|flybase:FBgn0026313|dip:DIP-20815N|ensemblmetazoa:FBgn0026313(gene)|ensemblmetazoa:FBtr0074451(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0043197"(dendritic spine)|go:"GO:0048749"(compound eye development)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098793"(presynapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034	-	-	-	dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/11/03	2014/10/16	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	rogid:naV23VxHMWR+MDwcH91M2sI/NlU7227	intact-crc:14549A2C0703C5C3|rigid:hkbrfJX0O5+2/xGdp8irCqNEyYo	false	glutathione s tranferase tag:?-?|binding-associated region:?-?	ha tag:?-?	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P14599	uniprotkb:Q9W0K0	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	intact:EBI-74120|uniprotkb:Q9NH69|uniprotkb:Q8IGG5|ensemblmetazoa:FBpp0072523	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:jip1_drome(display_long)|uniprotkb:Protein eye developmental SP512(gene name synonym)|uniprotkb:APP-like-interacting protein 1(gene name synonym)|uniprotkb:Aplip1(gene name)|psi-mi:Aplip1(display_short)|uniprotkb:SP512(gene name synonym)|uniprotkb:CG1200(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-74201	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	refseq:NP_728573.1|refseq:NP_728574.1|flybase:FBgn0040281|dip:DIP-20311N|ensemblmetazoa:FBgn0040281(gene)|ensemblmetazoa:FBtr0072627(transcript)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0019894"(kinesin binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048491"(retrograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|rcsb pdb:4Z88	-	-	-	dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2003/11/03	2014/10/16	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	rogid:fOLEqOpPaBndqMQqgReljn1SA+I7227	intact-crc:C737A33D56FBF7F3|rigid:Oacz3d8BVemMAGO0g4NTiusy1Qg	false	flag tag:?-?	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P14599	uniprotkb:Q9W0K0	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	intact:EBI-74120|uniprotkb:Q9NH69|uniprotkb:Q8IGG5|ensemblmetazoa:FBpp0072523	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:jip1_drome(display_long)|uniprotkb:Protein eye developmental SP512(gene name synonym)|uniprotkb:APP-like-interacting protein 1(gene name synonym)|uniprotkb:Aplip1(gene name)|psi-mi:Aplip1(display_short)|uniprotkb:SP512(gene name synonym)|uniprotkb:CG1200(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-74208	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	refseq:NP_728573.1|refseq:NP_728574.1|flybase:FBgn0040281|dip:DIP-20311N|ensemblmetazoa:FBgn0040281(gene)|ensemblmetazoa:FBtr0072627(transcript)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0019894"(kinesin binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048491"(retrograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|rcsb pdb:4Z88	-	-	-	dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2003/11/03	2014/10/16	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	rogid:fOLEqOpPaBndqMQqgReljn1SA+I7227	intact-crc:186B0507A915B9BC|rigid:Oacz3d8BVemMAGO0g4NTiusy1Qg	false	-	flag tag:?-?	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q9W0K0	uniprotkb:Q9W0K0	intact:EBI-74120|uniprotkb:Q9NH69|uniprotkb:Q8IGG5|ensemblmetazoa:FBpp0072523	intact:EBI-74120|uniprotkb:Q9NH69|uniprotkb:Q8IGG5|ensemblmetazoa:FBpp0072523	psi-mi:jip1_drome(display_long)|uniprotkb:Protein eye developmental SP512(gene name synonym)|uniprotkb:APP-like-interacting protein 1(gene name synonym)|uniprotkb:Aplip1(gene name)|psi-mi:Aplip1(display_short)|uniprotkb:SP512(gene name synonym)|uniprotkb:CG1200(orf name)	psi-mi:jip1_drome(display_long)|uniprotkb:Protein eye developmental SP512(gene name synonym)|uniprotkb:APP-like-interacting protein 1(gene name synonym)|uniprotkb:Aplip1(gene name)|psi-mi:Aplip1(display_short)|uniprotkb:SP512(gene name synonym)|uniprotkb:CG1200(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-74260	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_728573.1|refseq:NP_728574.1|flybase:FBgn0040281|dip:DIP-20311N|ensemblmetazoa:FBgn0040281(gene)|ensemblmetazoa:FBtr0072627(transcript)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0019894"(kinesin binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048491"(retrograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|rcsb pdb:4Z88	refseq:NP_728573.1|refseq:NP_728574.1|flybase:FBgn0040281|dip:DIP-20311N|ensemblmetazoa:FBgn0040281(gene)|ensemblmetazoa:FBtr0072627(transcript)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0019894"(kinesin binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048491"(retrograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|rcsb pdb:4Z88	-	-	-	dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2003/11/03	2014/10/16	rogid:fOLEqOpPaBndqMQqgReljn1SA+I7227	rogid:fOLEqOpPaBndqMQqgReljn1SA+I7227	intact-crc:63AF1030DF0D3D6C|rigid:/LkNtQrzPoAt7+qOOdqRb1J0E+s	false	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P46824	uniprotkb:Q9W0K0	intact:EBI-77490|ensemblmetazoa:FBpp0075683|ensemblmetazoa:FBpp0303945|uniprotkb:Q9VU05	intact:EBI-74120|uniprotkb:Q9NH69|uniprotkb:Q8IGG5|ensemblmetazoa:FBpp0072523	psi-mi:klc_drome(display_long)|uniprotkb:Klc(gene name)|psi-mi:Klc(display_short)|uniprotkb:CG5433(orf name)	psi-mi:jip1_drome(display_long)|uniprotkb:Protein eye developmental SP512(gene name synonym)|uniprotkb:APP-like-interacting protein 1(gene name synonym)|uniprotkb:Aplip1(gene name)|psi-mi:Aplip1(display_short)|uniprotkb:SP512(gene name synonym)|uniprotkb:CG1200(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-77455	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:FBgn0010235(gene)|ensemblmetazoa:FBtr0075951(transcript)|ensemblmetazoa:FBtr0331555(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0046843"(dorsal appendage formation)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|reactome:R-DME-6811434|reactome:R-DME-983189|refseq:NP_524049.1|flybase:FBgn0010235|refseq:NP_001261780.1|dip:DIP-19091N	refseq:NP_728573.1|refseq:NP_728574.1|flybase:FBgn0040281|dip:DIP-20311N|ensemblmetazoa:FBgn0040281(gene)|ensemblmetazoa:FBtr0072627(transcript)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0019894"(kinesin binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048491"(retrograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|rcsb pdb:4Z88	-	-	-	dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2003/11/03	2014/10/16	rogid:ggplfkjiCros+D00Q3kiqwGcRrE7227	rogid:fOLEqOpPaBndqMQqgReljn1SA+I7227	intact-crc:59251701EA91830D|rigid:vwHD02ksiZPzCdOuJHagTikXslM	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q23977	uniprotkb:Q9W0K0	intact:EBI-74214|uniprotkb:O18411|uniprotkb:Q8SZ04|uniprotkb:Q8SZZ1|uniprotkb:Q9I7S3|ensemblmetazoa:FBpp0073578	intact:EBI-74120|uniprotkb:Q9NH69|uniprotkb:Q8IGG5|ensemblmetazoa:FBpp0072523	psi-mi:hep_drome(display_long)|uniprotkb:hep(gene name)|psi-mi:hep(display_short)|uniprotkb:hem(gene name synonym)|uniprotkb:MKK7(gene name synonym)|uniprotkb:CG4353(orf name)	psi-mi:jip1_drome(display_long)|uniprotkb:Protein eye developmental SP512(gene name synonym)|uniprotkb:APP-like-interacting protein 1(gene name synonym)|uniprotkb:Aplip1(gene name)|psi-mi:Aplip1(display_short)|uniprotkb:SP512(gene name synonym)|uniprotkb:CG1200(orf name)	psi-mi:"MI:0096"(pull down)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-74230	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_727661.1|flybase:FBgn0010303|refseq:NP_511142.2|refseq:NP_001259501.1|dip:DIP-30870N|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-209397|reactome:R-DME-209447|reactome:R-DME-350376|go:"GO:0042060"(wound healing)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046528"(imaginal disc fusion)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046844"(chorion micropyle formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0048675"(axon extension)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903688"(positive regulation of border follicle cell migration)|ensemblmetazoa:FBgn0010303(gene)|ensemblmetazoa:FBtr0073747(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007254"(JNK cascade)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007561"(imaginal disc eversion)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008545"(JUN kinase kinase activity)|go:"GO:0009408"(response to heat)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030424"(axon)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0034769"(basement membrane disassembly)|go:"GO:0035006"(melanization defense response)|go:"GO:0036335"(intestinal stem cell homeostasis)	refseq:NP_728573.1|refseq:NP_728574.1|flybase:FBgn0040281|dip:DIP-20311N|ensemblmetazoa:FBgn0040281(gene)|ensemblmetazoa:FBtr0072627(transcript)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0019894"(kinesin binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048491"(retrograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|rcsb pdb:4Z88	-	-	-	comment:Flag tagged hep and APLIP1 is expressed as a GST-fusion protein.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/11/03	2014/10/16	rogid:XTLY74pOC/Mk9P0Rrq5DSUM+K0w7227	rogid:fOLEqOpPaBndqMQqgReljn1SA+I7227	intact-crc:52D1A5EC2AB26A74|rigid:KR7K+rrLPMjQwE0AH83NtNTfvBs	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9W0K0	uniprotkb:Q9W0K0	intact:EBI-74120|uniprotkb:Q9NH69|uniprotkb:Q8IGG5|ensemblmetazoa:FBpp0072523	intact:EBI-74120|uniprotkb:Q9NH69|uniprotkb:Q8IGG5|ensemblmetazoa:FBpp0072523	psi-mi:jip1_drome(display_long)|uniprotkb:Protein eye developmental SP512(gene name synonym)|uniprotkb:APP-like-interacting protein 1(gene name synonym)|uniprotkb:Aplip1(gene name)|psi-mi:Aplip1(display_short)|uniprotkb:SP512(gene name synonym)|uniprotkb:CG1200(orf name)	psi-mi:jip1_drome(display_long)|uniprotkb:Protein eye developmental SP512(gene name synonym)|uniprotkb:APP-like-interacting protein 1(gene name synonym)|uniprotkb:Aplip1(gene name)|psi-mi:Aplip1(display_short)|uniprotkb:SP512(gene name synonym)|uniprotkb:CG1200(orf name)	psi-mi:"MI:0096"(pull down)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-74235	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_728573.1|refseq:NP_728574.1|flybase:FBgn0040281|dip:DIP-20311N|ensemblmetazoa:FBgn0040281(gene)|ensemblmetazoa:FBtr0072627(transcript)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0019894"(kinesin binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048491"(retrograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|rcsb pdb:4Z88	refseq:NP_728573.1|refseq:NP_728574.1|flybase:FBgn0040281|dip:DIP-20311N|ensemblmetazoa:FBgn0040281(gene)|ensemblmetazoa:FBtr0072627(transcript)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0019894"(kinesin binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048491"(retrograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|rcsb pdb:4Z88	-	-	-	comment:GST-APLIP1 was used to pull down untagged APLIP1.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/11/03	2014/10/16	rogid:fOLEqOpPaBndqMQqgReljn1SA+I7227	rogid:fOLEqOpPaBndqMQqgReljn1SA+I7227	intact-crc:EC854D468ADC39C8|rigid:/LkNtQrzPoAt7+qOOdqRb1J0E+s	false	-	glutathione s tranferase tag:?-?	2	2	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q23977	uniprotkb:Q9W0K0	intact:EBI-74214|uniprotkb:O18411|uniprotkb:Q8SZ04|uniprotkb:Q8SZZ1|uniprotkb:Q9I7S3|ensemblmetazoa:FBpp0073578	intact:EBI-74120|uniprotkb:Q9NH69|uniprotkb:Q8IGG5|ensemblmetazoa:FBpp0072523	psi-mi:hep_drome(display_long)|uniprotkb:hep(gene name)|psi-mi:hep(display_short)|uniprotkb:hem(gene name synonym)|uniprotkb:MKK7(gene name synonym)|uniprotkb:CG4353(orf name)	psi-mi:jip1_drome(display_long)|uniprotkb:Protein eye developmental SP512(gene name synonym)|uniprotkb:APP-like-interacting protein 1(gene name synonym)|uniprotkb:Aplip1(gene name)|psi-mi:Aplip1(display_short)|uniprotkb:SP512(gene name synonym)|uniprotkb:CG1200(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-74245	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_727661.1|flybase:FBgn0010303|refseq:NP_511142.2|refseq:NP_001259501.1|dip:DIP-30870N|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-209397|reactome:R-DME-209447|reactome:R-DME-350376|go:"GO:0042060"(wound healing)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046528"(imaginal disc fusion)|go:"GO:0046529"(imaginal disc fusion, thorax closure)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046844"(chorion micropyle formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0048675"(axon extension)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903688"(positive regulation of border follicle cell migration)|ensemblmetazoa:FBgn0010303(gene)|ensemblmetazoa:FBtr0073747(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007254"(JNK cascade)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007561"(imaginal disc eversion)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008545"(JUN kinase kinase activity)|go:"GO:0009408"(response to heat)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030381"(chorion-containing eggshell pattern formation)|go:"GO:0030424"(axon)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0034769"(basement membrane disassembly)|go:"GO:0035006"(melanization defense response)|go:"GO:0036335"(intestinal stem cell homeostasis)	refseq:NP_728573.1|refseq:NP_728574.1|flybase:FBgn0040281|dip:DIP-20311N|ensemblmetazoa:FBgn0040281(gene)|ensemblmetazoa:FBtr0072627(transcript)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0019894"(kinesin binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048491"(retrograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036028|rcsb pdb:4Z88	-	-	-	comment:FLAG tagged Aplip1 and HA tagged Hep|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2003/11/03	2014/10/16	rogid:XTLY74pOC/Mk9P0Rrq5DSUM+K0w7227	rogid:fOLEqOpPaBndqMQqgReljn1SA+I7227	intact-crc:7569DD3D18C4795D|rigid:KR7K+rrLPMjQwE0AH83NtNTfvBs	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q9WV19	uniprotkb:P14599	intact:EBI-74563|ensembl:ENSMUSP00000047150	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	psi-mi:q9wv19_mouse(display_long)|uniprotkb:Cyp2g1(gene name)|psi-mi:Cyp2g1(display_short)	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Taru et al. (2002)	pubmed:11912189	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-74572	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000049685(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016712"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)|go:"GO:0019373"(epoxygenase P450 pathway)|go:"GO:0020037"(heme binding)|go:"GO:0042738"|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR008067(Cytochrome P450, E-class, group I, CYP2A-like)|interpro:IPR017972|interpro:IPR036396|ensembl:ENSMUST00000040944(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006082"(organic acid metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008392"(arachidonic acid epoxygenase activity)|go:"GO:0008395"(steroid hydroxylase activity)|refseq:NP_038837.1	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	-	-	-	comment:APP is FLAG tagged. Mouse JIP1 is HA tagged.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2003/11/03	2014/10/16	rogid:TvhecInmTtk0LxGkkwfG4D0Xmcg10090	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	intact-crc:9148830FB97F9E3A|rigid:QouqX/gKV5PiQ20zDb6Eo2aMdsU	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P14599	uniprotkb:Q9ERE9	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	intact:EBI-74576|ensembl:ENSMUSP00000023291|uniprotkb:Q9CXI4	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:jip2_mouse(display_long)|uniprotkb:Mapk8ip2(gene name)|psi-mi:Mapk8ip2(display_short)|uniprotkb:Ib2(gene name synonym)|uniprotkb:Jip2(gene name synonym)|uniprotkb:Islet-brain-2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-74593	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	ensembl:ENSMUSG00000022619(gene)|ensembl:ENSMUST00000023291(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0035176"(social behavior)|go:"GO:0007617"(mating behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046958"(nonassociative learning)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0014069"(postsynaptic density)|interpro:IPR001452(Src homology-3)|go:"GO:0019894"(kinesin binding)|interpro:IPR006020(Phosphotyrosine interaction region)|go:"GO:0019901"(protein kinase binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035637|mint:Q9ERE9|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|refseq:NP_068740.3	-	-	-	comment:APP is FLAG tagged. Mouse JIP2 is HA tagged.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2003/11/03	2014/10/16	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	rogid:NUVswDC52pSAuf8BL8b9wqVc8ng10090	intact-crc:DD9C2FEF26C95511|rigid:/tECgNwD3NcHku7kqnPLbrHB9Mw	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P14599	uniprotkb:Q9VX41	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	intact:EBI-74153|uniprotkb:Q960Z2|ensemblmetazoa:FBpp0074225	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:q9vx41_drome(display_long)|uniprotkb:X11L(gene name)|psi-mi:X11L(display_short)|uniprotkb:Mint(gene name synonym)|uniprotkb:CG5678(gene name synonym)|uniprotkb:Dmel\CG5675(gene name synonym)|uniprotkb:Dmint(gene name synonym)|uniprotkb:Dmint1(gene name synonym)|uniprotkb:MINT(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:X11-like(gene name synonym)|uniprotkb:X11Lalpha(gene name synonym)|uniprotkb:dX11(gene name synonym)|uniprotkb:dX11L(gene name synonym)|uniprotkb:dX11Lalpha(gene name synonym)|uniprotkb:x11(gene name synonym)|uniprotkb:x11Lalpha(gene name synonym)|uniprotkb:Dmel_CG5675(orf name)|uniprotkb:CG5675(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Taru et al. (2002)	pubmed:11912189	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-74600	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	refseq:NP_573224.2|flybase:FBgn0026313|dip:DIP-20815N|ensemblmetazoa:FBgn0026313(gene)|ensemblmetazoa:FBtr0074451(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0043197"(dendritic spine)|go:"GO:0048749"(compound eye development)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098793"(presynapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034	-	-	-	comment:APP was FLAG tagged.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2003/11/03	2014/10/16	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	rogid:naV23VxHMWR+MDwcH91M2sI/NlU7227	intact-crc:DFDF0F4FD1D8B06A|rigid:hkbrfJX0O5+2/xGdp8irCqNEyYo	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)