#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9NRD5 uniprotkb:Q16515 intact:EBI-79165|uniprotkb:O95906|ensembl:ENSP00000349465|ensembl:ENSP00000385205|intact:EBI-2622151|uniprotkb:B3KS52 intact:EBI-79149|uniprotkb:Q13553|uniprotkb:Q6DJU1|uniprotkb:Q8N3E2|uniprotkb:E9PBX2|ensembl:ENSP00000352934 psi-mi:pick1_human(display_long)|uniprotkb:PICK1(gene name)|psi-mi:PICK1(display_short)|uniprotkb:PRKCABP(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:asic2_human(display_long)|uniprotkb:ASIC2(gene name)|psi-mi:ASIC2(display_short)|uniprotkb:ACCN(gene name synonym)|uniprotkb:ACCN1(gene name synonym)|uniprotkb:Amiloride-sensitive brain sodium channel(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel 1, neuronal(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel neuronal 1(gene name synonym)|uniprotkb:BNAC1(gene name synonym)|uniprotkb:Brain sodium channel 1(gene name synonym)|uniprotkb:MDEG(gene name synonym)|uniprotkb:Mammalian degenerin homolog(gene name synonym) psi-mi:"MI:0018"(two hybrid) Hruska-Hageman et al. (2002) pubmed:11802773 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-79148 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100151(gene)|ensembl:ENST00000356976(transcript)|ensembl:ENST00000404072(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|refseq:NP_001034672.1|refseq:NP_001034673.1|refseq:NP_036539.1|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043113"(receptor clustering)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|mint:Q9NRD5|rcsb pdb:2GZV|rcsb pdb:6AR4|rcsb pdb:6BJN|rcsb pdb:6BJO|reactome:R-HSA-202733|reactome:R-HSA-416993 refseq:NP_001085.2|refseq:NP_899233.1|ensembl:ENSG00000108684(gene)|ensembl:ENST00000359872(transcript)|go:"GO:0003026"(regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007602"(phototransduction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010447"(response to acidic pH)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0022839"(ion gated channel activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0050915"(sensory perception of sour taste)|go:"GO:0050974"(detection of mechanical stimulus involved in sensory perception)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0098662"(inorganic cation transmembrane transport)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|rcsb pdb:6L6P|reactome:R-HSA-2672351 - - - comment:aa 470-512 of ACCN1 sufficient taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2003/12/05 2014/10/16 rogid:qRx+eNG7We8Oe0SQOekqpJpn8zk9606 rogid:ZlQ9b+ycydeYv3ubHSV3wf49NQs9606 intact-crc:AF22C502FA30FF9E|rigid:AZ/Mxf9T67ua2bnHnPfPwT4Ziho false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NRD5 uniprotkb:Q16515 intact:EBI-79165|uniprotkb:O95906|ensembl:ENSP00000349465|ensembl:ENSP00000385205|intact:EBI-2622151|uniprotkb:B3KS52 intact:EBI-79149|uniprotkb:Q13553|uniprotkb:Q6DJU1|uniprotkb:Q8N3E2|uniprotkb:E9PBX2|ensembl:ENSP00000352934 psi-mi:pick1_human(display_long)|uniprotkb:PICK1(gene name)|psi-mi:PICK1(display_short)|uniprotkb:PRKCABP(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:asic2_human(display_long)|uniprotkb:ASIC2(gene name)|psi-mi:ASIC2(display_short)|uniprotkb:ACCN(gene name synonym)|uniprotkb:ACCN1(gene name synonym)|uniprotkb:Amiloride-sensitive brain sodium channel(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel 1, neuronal(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel neuronal 1(gene name synonym)|uniprotkb:BNAC1(gene name synonym)|uniprotkb:Brain sodium channel 1(gene name synonym)|uniprotkb:MDEG(gene name synonym)|uniprotkb:Mammalian degenerin homolog(gene name synonym) psi-mi:"MI:0018"(two hybrid) Hruska-Hageman et al. (2002) pubmed:11802773 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-79220 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100151(gene)|ensembl:ENST00000356976(transcript)|ensembl:ENST00000404072(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|refseq:NP_001034672.1|refseq:NP_001034673.1|refseq:NP_036539.1|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043113"(receptor clustering)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|mint:Q9NRD5|rcsb pdb:2GZV|rcsb pdb:6AR4|rcsb pdb:6BJN|rcsb pdb:6BJO|reactome:R-HSA-202733|reactome:R-HSA-416993 refseq:NP_001085.2|refseq:NP_899233.1|ensembl:ENSG00000108684(gene)|ensembl:ENST00000359872(transcript)|go:"GO:0003026"(regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007602"(phototransduction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010447"(response to acidic pH)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0022839"(ion gated channel activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0050915"(sensory perception of sour taste)|go:"GO:0050974"(detection of mechanical stimulus involved in sensory perception)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0098662"(inorganic cation transmembrane transport)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|rcsb pdb:6L6P|reactome:R-HSA-2672351 - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2003/12/05 2014/10/16 rogid:qRx+eNG7We8Oe0SQOekqpJpn8zk9606 rogid:ZlQ9b+ycydeYv3ubHSV3wf49NQs9606 intact-crc:2B02DABB8E16D1F6|rigid:AZ/Mxf9T67ua2bnHnPfPwT4Ziho false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NRD5 uniprotkb:P78348 intact:EBI-79165|uniprotkb:O95906|ensembl:ENSP00000349465|ensembl:ENSP00000385205|intact:EBI-2622151|uniprotkb:B3KS52 intact:EBI-79189|uniprotkb:A3KN86|uniprotkb:P78349|uniprotkb:Q96CV2|uniprotkb:E5KBL7|ensembl:ENSP00000400228 psi-mi:pick1_human(display_long)|uniprotkb:PICK1(gene name)|psi-mi:PICK1(display_short)|uniprotkb:PRKCABP(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:asic1_human(display_long)|uniprotkb:ASIC1(gene name)|psi-mi:ASIC1(display_short)|uniprotkb:ACCN2(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel 2, neuronal(gene name synonym)|uniprotkb:BNAC2(gene name synonym)|uniprotkb:Brain sodium channel 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Hruska-Hageman et al. (2002) pubmed:11802773 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-79188 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100151(gene)|ensembl:ENST00000356976(transcript)|ensembl:ENST00000404072(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|refseq:NP_001034672.1|refseq:NP_001034673.1|refseq:NP_036539.1|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043113"(receptor clustering)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|mint:Q9NRD5|rcsb pdb:2GZV|rcsb pdb:6AR4|rcsb pdb:6BJN|rcsb pdb:6BJO|reactome:R-HSA-202733|reactome:R-HSA-416993 refseq:NP_001086.2|refseq:NP_064423.2|refseq:NP_001243759.1|ensembl:ENST00000447966(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007165"(signal transduction)|go:"GO:0007613"(memory)|ensembl:ENSG00000110881(gene)|go:"GO:0008306"(associative learning)|go:"GO:0009268"(response to pH)|go:"GO:0009986"(cell surface)|go:"GO:0010447"(response to acidic pH)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0022839"(ion gated channel activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0044736"(acid-sensing ion channel activity)|go:"GO:0045202"(synapse)|go:"GO:0050915"(sensory perception of sour taste)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071467"(cellular response to pH)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|rcsb pdb:6L6I|rcsb pdb:6L6N|rcsb pdb:7CFS|rcsb pdb:7CFT|reactome:R-HSA-2672351|go:"GO:0046929"(negative regulation of neurotransmitter secretion) - - - comment:aa 505 - 574 of ACCN2 sufficient taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2003/12/05 2014/10/16 rogid:qRx+eNG7We8Oe0SQOekqpJpn8zk9606 rogid:j028gI5GihfiamkozKrb4ls7pgs9606 intact-crc:103784B9C3908731|rigid:K681JgQIJcCbkgsVocU5ZdqfypM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16515 uniprotkb:Q9NRD5 intact:EBI-79149|uniprotkb:Q13553|uniprotkb:Q6DJU1|uniprotkb:Q8N3E2|uniprotkb:E9PBX2|ensembl:ENSP00000352934 intact:EBI-79165|uniprotkb:O95906|ensembl:ENSP00000349465|ensembl:ENSP00000385205|intact:EBI-2622151|uniprotkb:B3KS52 psi-mi:asic2_human(display_long)|uniprotkb:ASIC2(gene name)|psi-mi:ASIC2(display_short)|uniprotkb:ACCN(gene name synonym)|uniprotkb:ACCN1(gene name synonym)|uniprotkb:Amiloride-sensitive brain sodium channel(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel 1, neuronal(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel neuronal 1(gene name synonym)|uniprotkb:BNAC1(gene name synonym)|uniprotkb:Brain sodium channel 1(gene name synonym)|uniprotkb:MDEG(gene name synonym)|uniprotkb:Mammalian degenerin homolog(gene name synonym) psi-mi:pick1_human(display_long)|uniprotkb:PICK1(gene name)|psi-mi:PICK1(display_short)|uniprotkb:PRKCABP(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Hruska-Hageman et al. (2002) pubmed:11802773 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-79206 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001085.2|refseq:NP_899233.1|ensembl:ENSG00000108684(gene)|ensembl:ENST00000359872(transcript)|go:"GO:0003026"(regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007602"(phototransduction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010447"(response to acidic pH)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0022839"(ion gated channel activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0050915"(sensory perception of sour taste)|go:"GO:0050974"(detection of mechanical stimulus involved in sensory perception)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0098662"(inorganic cation transmembrane transport)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|rcsb pdb:6L6P|reactome:R-HSA-2672351 ensembl:ENSG00000100151(gene)|ensembl:ENST00000356976(transcript)|ensembl:ENST00000404072(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|refseq:NP_001034672.1|refseq:NP_001034673.1|refseq:NP_036539.1|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043113"(receptor clustering)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|mint:Q9NRD5|rcsb pdb:2GZV|rcsb pdb:6AR4|rcsb pdb:6BJN|rcsb pdb:6BJO|reactome:R-HSA-202733|reactome:R-HSA-416993 - - - comment:aa 509- 512 of ACCN1 are necessary taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2003/12/05 2014/10/16 rogid:ZlQ9b+ycydeYv3ubHSV3wf49NQs9606 rogid:qRx+eNG7We8Oe0SQOekqpJpn8zk9606 intact-crc:305AC6FE6CBEB26E|rigid:AZ/Mxf9T67ua2bnHnPfPwT4Ziho false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P78348 uniprotkb:Q9NRD5 intact:EBI-79189|uniprotkb:A3KN86|uniprotkb:P78349|uniprotkb:Q96CV2|uniprotkb:E5KBL7|ensembl:ENSP00000400228 intact:EBI-79165|uniprotkb:O95906|ensembl:ENSP00000349465|ensembl:ENSP00000385205|intact:EBI-2622151|uniprotkb:B3KS52 psi-mi:asic1_human(display_long)|uniprotkb:ASIC1(gene name)|psi-mi:ASIC1(display_short)|uniprotkb:ACCN2(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel 2, neuronal(gene name synonym)|uniprotkb:BNAC2(gene name synonym)|uniprotkb:Brain sodium channel 2(gene name synonym) psi-mi:pick1_human(display_long)|uniprotkb:PICK1(gene name)|psi-mi:PICK1(display_short)|uniprotkb:PRKCABP(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Hruska-Hageman et al. (2002) pubmed:11802773 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-79211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001086.2|refseq:NP_064423.2|refseq:NP_001243759.1|ensembl:ENST00000447966(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007165"(signal transduction)|go:"GO:0007613"(memory)|ensembl:ENSG00000110881(gene)|go:"GO:0008306"(associative learning)|go:"GO:0009268"(response to pH)|go:"GO:0009986"(cell surface)|go:"GO:0010447"(response to acidic pH)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0022839"(ion gated channel activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0044736"(acid-sensing ion channel activity)|go:"GO:0045202"(synapse)|go:"GO:0050915"(sensory perception of sour taste)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071467"(cellular response to pH)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|rcsb pdb:6L6I|rcsb pdb:6L6N|rcsb pdb:7CFS|rcsb pdb:7CFT|reactome:R-HSA-2672351|go:"GO:0046929"(negative regulation of neurotransmitter secretion) ensembl:ENSG00000100151(gene)|ensembl:ENST00000356976(transcript)|ensembl:ENST00000404072(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|refseq:NP_001034672.1|refseq:NP_001034673.1|refseq:NP_036539.1|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043113"(receptor clustering)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|mint:Q9NRD5|rcsb pdb:2GZV|rcsb pdb:6AR4|rcsb pdb:6BJN|rcsb pdb:6BJO|reactome:R-HSA-202733|reactome:R-HSA-416993 - - - comment:aa 571 - 574 of ACCN2 are necessary taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2003/12/05 2014/10/16 rogid:j028gI5GihfiamkozKrb4ls7pgs9606 rogid:qRx+eNG7We8Oe0SQOekqpJpn8zk9606 intact-crc:28092A0CC85D070C|rigid:K681JgQIJcCbkgsVocU5ZdqfypM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P78348 uniprotkb:Q9NRD5 intact:EBI-79189|uniprotkb:A3KN86|uniprotkb:P78349|uniprotkb:Q96CV2|uniprotkb:E5KBL7|ensembl:ENSP00000400228 intact:EBI-79165|uniprotkb:O95906|ensembl:ENSP00000349465|ensembl:ENSP00000385205|intact:EBI-2622151|uniprotkb:B3KS52 psi-mi:asic1_human(display_long)|uniprotkb:ASIC1(gene name)|psi-mi:ASIC1(display_short)|uniprotkb:ACCN2(gene name synonym)|uniprotkb:Amiloride-sensitive cation channel 2, neuronal(gene name synonym)|uniprotkb:BNAC2(gene name synonym)|uniprotkb:Brain sodium channel 2(gene name synonym) psi-mi:pick1_human(display_long)|uniprotkb:PICK1(gene name)|psi-mi:PICK1(display_short)|uniprotkb:PRKCABP(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:"MI:0428"(imaging technique) Hruska-Hageman et al. (2002) pubmed:11802773 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-79215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001086.2|refseq:NP_064423.2|refseq:NP_001243759.1|ensembl:ENST00000447966(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007165"(signal transduction)|go:"GO:0007613"(memory)|ensembl:ENSG00000110881(gene)|go:"GO:0008306"(associative learning)|go:"GO:0009268"(response to pH)|go:"GO:0009986"(cell surface)|go:"GO:0010447"(response to acidic pH)|go:"GO:0015280"(ligand-gated sodium channel activity)|go:"GO:0022839"(ion gated channel activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0044736"(acid-sensing ion channel activity)|go:"GO:0045202"(synapse)|go:"GO:0050915"(sensory perception of sour taste)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071467"(cellular response to pH)|interpro:IPR001873(Na+ channel, amiloride-sensitive)|interpro:IPR004724(Epithelial sodium channel)|interpro:IPR020903|rcsb pdb:6L6I|rcsb pdb:6L6N|rcsb pdb:7CFS|rcsb pdb:7CFT|reactome:R-HSA-2672351|go:"GO:0046929"(negative regulation of neurotransmitter secretion) ensembl:ENSG00000100151(gene)|ensembl:ENST00000356976(transcript)|ensembl:ENST00000404072(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|refseq:NP_001034672.1|refseq:NP_001034673.1|refseq:NP_036539.1|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043113"(receptor clustering)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|mint:Q9NRD5|rcsb pdb:2GZV|rcsb pdb:6AR4|rcsb pdb:6BJN|rcsb pdb:6BJO|reactome:R-HSA-202733|reactome:R-HSA-416993 - - - - taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons) - 2003/12/05 2014/10/16 rogid:j028gI5GihfiamkozKrb4ls7pgs9606 rogid:qRx+eNG7We8Oe0SQOekqpJpn8zk9606 intact-crc:0FFD8F0AE8278F11|rigid:K681JgQIJcCbkgsVocU5ZdqfypM false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)