#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P27049 uniprotkb:Q9EP80 intact:EBI-78953|ensembl:ENSRNOP00000004408 intact:EBI-77728|uniprotkb:Q546X4|uniprotkb:Q925D1 psi-mi:btg2_rat(display_long)|uniprotkb:Btg2(gene name)|psi-mi:Btg2(display_short)|uniprotkb:Pc3(gene name synonym)|uniprotkb:BTG family member 2(gene name synonym)|uniprotkb:NGF-inducible anti-proliferative protein PC3(gene name synonym) psi-mi:pick1_rat(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lin et al. (2001) pubmed:11237868 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-79266 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2225|refseq:NP_058955.1|go:"GO:0006479"(protein methylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010033"(response to organic substance)|ensembl:ENSRNOG00000003300(gene)|ensembl:ENSRNOT00000004408(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031175"(neuron projection development)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR033328|interpro:IPR033332|interpro:IPR036054|reactome:R-RNO-6804115 rgd:69437|refseq:NP_445912.1|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|rcsb pdb:2LUI|rcsb pdb:2PKU|rcsb pdb:3HPK|rcsb pdb:3HPM|reactome:R-RNO-416993|mint:Q9EP80|dip:DIP-30941N - - - comment:aa 49 - 122 of BTG2 sufficient taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2003/12/05 2014/10/16 rogid:Ex74J/rVuATvQmvM1CtdUjZU8Xg10116 rogid:py6ehB6OMAq34c71Oad5GTeNfHg10116 intact-crc:483D2AFDCD80C47B|rigid:tSc2jAmgoemXBjjWAy/nTc6qGwE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EP80 uniprotkb:P27049 intact:EBI-77728|uniprotkb:Q546X4|uniprotkb:Q925D1 intact:EBI-78953|ensembl:ENSRNOP00000004408 psi-mi:pick1_rat(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:btg2_rat(display_long)|uniprotkb:Btg2(gene name)|psi-mi:Btg2(display_short)|uniprotkb:Pc3(gene name synonym)|uniprotkb:BTG family member 2(gene name synonym)|uniprotkb:NGF-inducible anti-proliferative protein PC3(gene name synonym) psi-mi:"MI:0096"(pull down) Lin et al. (2001) pubmed:11237868 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-79272 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:69437|refseq:NP_445912.1|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|rcsb pdb:2LUI|rcsb pdb:2PKU|rcsb pdb:3HPK|rcsb pdb:3HPM|reactome:R-RNO-416993|mint:Q9EP80|dip:DIP-30941N rgd:2225|refseq:NP_058955.1|go:"GO:0006479"(protein methylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010033"(response to organic substance)|ensembl:ENSRNOG00000003300(gene)|ensembl:ENSRNOT00000004408(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031175"(neuron projection development)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR033328|interpro:IPR033332|interpro:IPR036054|reactome:R-RNO-6804115 - - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2003/12/05 2014/10/16 rogid:py6ehB6OMAq34c71Oad5GTeNfHg10116 rogid:Ex74J/rVuATvQmvM1CtdUjZU8Xg10116 intact-crc:608E9C73831383AA|rigid:tSc2jAmgoemXBjjWAy/nTc6qGwE false glutathione s tranferase tag:?-? radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27049 uniprotkb:Q9EP80 intact:EBI-78953|ensembl:ENSRNOP00000004408 intact:EBI-77728|uniprotkb:Q546X4|uniprotkb:Q925D1 psi-mi:btg2_rat(display_long)|uniprotkb:Btg2(gene name)|psi-mi:Btg2(display_short)|uniprotkb:Pc3(gene name synonym)|uniprotkb:BTG family member 2(gene name synonym)|uniprotkb:NGF-inducible anti-proliferative protein PC3(gene name synonym) psi-mi:pick1_rat(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Lin et al. (2001) pubmed:11237868 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-79276 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2225|refseq:NP_058955.1|go:"GO:0006479"(protein methylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010033"(response to organic substance)|ensembl:ENSRNOG00000003300(gene)|ensembl:ENSRNOT00000004408(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031175"(neuron projection development)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR033328|interpro:IPR033332|interpro:IPR036054|reactome:R-RNO-6804115 rgd:69437|refseq:NP_445912.1|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|rcsb pdb:2LUI|rcsb pdb:2PKU|rcsb pdb:3HPK|rcsb pdb:3HPM|reactome:R-RNO-416993|mint:Q9EP80|dip:DIP-30941N - - - - taxid:10090(mouse)|taxid:10090(Mus musculus) - 2003/12/05 2014/10/16 rogid:Ex74J/rVuATvQmvM1CtdUjZU8Xg10116 rogid:py6ehB6OMAq34c71Oad5GTeNfHg10116 intact-crc:3DC56556DAD82001|rigid:tSc2jAmgoemXBjjWAy/nTc6qGwE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)