#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UIK4 uniprotkb:Q9UIK4 intact:EBI-77154|uniprotkb:O75892|uniprotkb:Q24JS1|uniprotkb:E9JGM7|ensembl:ENSP00000261891|ensembl:ENSP00000408277 intact:EBI-77154|uniprotkb:O75892|uniprotkb:Q24JS1|uniprotkb:E9JGM7|ensembl:ENSP00000261891|ensembl:ENSP00000408277 psi-mi:dapk2_human(display_long)|uniprotkb:DAPK2(gene name)|psi-mi:DAPK2(display_short)|uniprotkb:DAP-kinase-related protein 1(gene name synonym) psi-mi:dapk2_human(display_long)|uniprotkb:DAPK2(gene name)|psi-mi:DAPK2(display_short)|uniprotkb:DAP-kinase-related protein 1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Shani et al. (2001) pubmed:11230133 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-77215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055141.2|refseq:XP_011519718.1|ensembl:ENSG00000035664(gene)|ensembl:ENST00000261891(transcript)|ensembl:ENST00000457488(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034423"(autophagosome lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043276"(anoikis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000424"(positive regulation of eosinophil chemotaxis)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1WMK|rcsb pdb:1WRZ|rcsb pdb:1Z9X|rcsb pdb:1ZUZ|rcsb pdb:1ZWS|rcsb pdb:2A27|rcsb pdb:2A2A|rcsb pdb:2CKE|rcsb pdb:6PAW|reactome:R-HSA-418889 refseq:NP_055141.2|refseq:XP_011519718.1|ensembl:ENSG00000035664(gene)|ensembl:ENST00000261891(transcript)|ensembl:ENST00000457488(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034423"(autophagosome lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043276"(anoikis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000424"(positive regulation of eosinophil chemotaxis)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1WMK|rcsb pdb:1WRZ|rcsb pdb:1Z9X|rcsb pdb:1ZUZ|rcsb pdb:1ZWS|rcsb pdb:2A27|rcsb pdb:2A2A|rcsb pdb:2CKE|rcsb pdb:6PAW|reactome:R-HSA-418889 go:"GO:0016506"(obsolete apoptosis activator activity)|go:"GO:0006917" - - comment:"Serine at 308 must be dephosphorylated for homdimerization (and induction of apoptosis) to occur."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2003/11/25 2014/10/16 rogid:BfVpnvUBAjf3E3djVaqnEqbGP8Q9606 rogid:BfVpnvUBAjf3E3djVaqnEqbGP8Q9606 intact-crc:9D12A96C4626A8C1|rigid:3hIpUAtCWO/WlUsHK7235TWFH28 false flag tag:?-?|binding-associated region:?-? flag tag:?-?|binding-associated region:?-? 2 0 psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot)