#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P39935 uniprotkb:P07260 intact:EBI-9002|ensemblfungi:YGR162W|uniprotkb:D6VUU6 intact:EBI-150|uniprotkb:D6W1T0|ensemblfungi:YOL139C psi-mi:if4f1_yeast(display_long)|uniprotkb:YGR162W(locus name)|uniprotkb:TIF4631(gene name)|psi-mi:TIF4631(display_short)|uniprotkb:eIF4G1(gene name synonym)|uniprotkb:mRNA cap-binding protein complex subunit p150(gene name synonym) psi-mi:if4e_yeast(display_long)|uniprotkb:CDC33(gene name)|psi-mi:CDC33(display_short)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:TIF45(gene name synonym)|uniprotkb:YOL139C(locus name) psi-mi:"MI:0107"(surface plasmon resonance) von et al. (2000) pubmed:10887196 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-74695 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR162W(gene)|ensemblfungi:YGR162W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0034063"(stress granule assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|go:"GO:1902280"(regulation of RNA helicase activity)|rcsb pdb:2VSO|rcsb pdb:2VSX|rcsb pdb:6Z29|reactome:R-SCE-156827|reactome:R-SCE-166208|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|reactome:R-SCE-975956|reactome:R-SCE-975957|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022745|interpro:IPR036211|rcsb pdb:1RF8|refseq:NP_011678.3|sgd:S000003394|mint:P39935|dip:DIP-985N refseq:NP_014502.1|sgd:S000005499|mint:P07260|dip:DIP-1223N|ensemblfungi:YOL139C(gene)|ensemblfungi:YOL139C_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|rcsb pdb:1AP8|rcsb pdb:1RF8|rcsb pdb:6FC1|rcsb pdb:6FC2|rcsb pdb:6FC3|reactome:R-SCE-156827|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702 intact:EBI-74692(intact-secondary)|pubmed:10887196(primary-reference) crc64:391256802F86118E crc64:5B9162E1BD0B1BDE - taxid:-1(in vitro)|taxid:-1(In vitro) - 2003/10/31 2014/10/16 rogid:l5wtszbSL7dltfdiDAVe5zYnxVc559292 rogid:KMyHDLtsgyJ7kPBwQktVQKsBPug559292 intact-crc:7AF219E57D9E9EFE|rigid:8y/k9EKP4TktkHmhj78g6n9uA6M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)