#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P40792 uniprotkb:P48554 intact:EBI-74845|uniprotkb:Q9W0H7|ensemblmetazoa:FBpp0072614|ensemblmetazoa:FBpp0304252 intact:EBI-74869|uniprotkb:Q540X5|uniprotkb:Q9VS69|ensemblmetazoa:FBpp0076577|ensemblmetazoa:FBpp0305023 psi-mi:rac1_drome(display_long)|uniprotkb:Rac1(gene name)|psi-mi:Rac1(display_short)|uniprotkb:RacA(gene name synonym)|uniprotkb:CG2248(orf name) psi-mi:rac2_drome(display_long)|uniprotkb:Rac2(gene name)|psi-mi:Rac2(display_short)|uniprotkb:RacB(gene name synonym)|uniprotkb:CG8556(orf name) psi-mi:"MI:0096"(pull down) Newsome et al. (2000) pubmed:10847683 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-75904 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476950.1|flybase:FBgn0010333|refseq:NP_001261247.1|ensemblmetazoa:FBgn0010333(gene)|ensemblmetazoa:FBtr0072730(transcript)|ensemblmetazoa:FBtr0331868(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002433"(immune response-regulating cell surface receptor signaling pathway involved in phagocytosis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007394"(dorsal closure, elongation of leading edge cells)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007516"(hemocyte development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007613"(memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008258"(head involution)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0016028"(rhabdomere)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016203"(muscle attachment)|go:"GO:0016358"(dendrite development)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035010"(encapsulation of foreign target)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0035320"(imaginal disc-derived wing hair site selection)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0048675"(axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0055001"(muscle cell development)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097206"(nephrocyte filtration)|go:"GO:0110125"(negative regulation of myotube cell migration)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1903391"(regulation of adherens junction organization)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-114604|reactome:R-DME-1433557|reactome:R-DME-193648|reactome:R-DME-2029482|reactome:R-DME-2871796|reactome:R-DME-350376|reactome:R-DME-376172|reactome:R-DME-389359|reactome:R-DME-3928662|reactome:R-DME-3928664|reactome:R-DME-3928665|reactome:R-DME-399954|reactome:R-DME-4086400|reactome:R-DME-4420097|reactome:R-DME-445144|reactome:R-DME-5218920|reactome:R-DME-5625740|reactome:R-DME-5627123|reactome:R-DME-5663213|reactome:R-DME-5687128|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-9013149|reactome:R-DME-9013404|reactome:R-DME-9013407|reactome:R-DME-9706019|reactome:R-DME-983231 refseq:NP_648121.1|flybase:FBgn0014011|refseq:NP_001261517.1|dip:DIP-18225N|ensemblmetazoa:FBgn0014011(gene)|ensemblmetazoa:FBtr0076867(transcript)|ensemblmetazoa:FBtr0332800(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002118"(aggressive behavior)|go:"GO:0002433"(immune response-regulating cell surface receptor signaling pathway involved in phagocytosis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007394"(dorsal closure, elongation of leading edge cells)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007617"(mating behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008258"(head involution)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0016203"(muscle attachment)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035010"(encapsulation of foreign target)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035099"(hemocyte migration)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1903391"(regulation of adherens junction organization)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-114604|reactome:R-DME-4086400|reactome:R-DME-9013404|reactome:R-DME-9013407|reactome:R-DME-9706019 - - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2003/11/18 2014/10/16 rogid:nVrsdRuWmYjJp67rd4Es0mFDuUU7227 rogid:PNIBHOg5t2eu9wEta4DW1OboF0w7227 intact-crc:D177F61176DF399F|rigid:DD8DZ+Io/JYis9K5UVfBgSewKko false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P48554 uniprotkb:Q9VI13 intact:EBI-74869|uniprotkb:Q540X5|uniprotkb:Q9VS69|ensemblmetazoa:FBpp0076577|ensemblmetazoa:FBpp0305023 intact:EBI-74826|intact:EBI-123979|intact:EBI-466309|uniprotkb:Q24190|uniprotkb:Q24213|ensemblmetazoa:FBpp0081211|ensemblmetazoa:FBpp0081212|ensemblmetazoa:FBpp0081213|ensemblmetazoa:FBpp0306606|ensemblmetazoa:FBpp0306611 psi-mi:rac2_drome(display_long)|uniprotkb:Rac2(gene name)|psi-mi:Rac2(display_short)|uniprotkb:RacB(gene name synonym)|uniprotkb:CG8556(orf name) psi-mi:pak_drome(display_long)|uniprotkb:Pak(gene name)|psi-mi:Pak(display_short)|uniprotkb:DPAK(gene name synonym)|uniprotkb:Dpak1(gene name synonym)|uniprotkb:CG10295(orf name) psi-mi:"MI:0096"(pull down) Newsome et al. (2000) pubmed:10847683 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-75907 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_648121.1|flybase:FBgn0014011|refseq:NP_001261517.1|dip:DIP-18225N|ensemblmetazoa:FBgn0014011(gene)|ensemblmetazoa:FBtr0076867(transcript)|ensemblmetazoa:FBtr0332800(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002118"(aggressive behavior)|go:"GO:0002433"(immune response-regulating cell surface receptor signaling pathway involved in phagocytosis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007394"(dorsal closure, elongation of leading edge cells)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007617"(mating behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008258"(head involution)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0016203"(muscle attachment)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035010"(encapsulation of foreign target)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035099"(hemocyte migration)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1903391"(regulation of adherens junction organization)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-114604|reactome:R-DME-4086400|reactome:R-DME-9013404|reactome:R-DME-9013407|reactome:R-DME-9706019 flybase:FBgn0267698|refseq:NP_001262309.1|refseq:NP_001262313.1|refseq:NP_524681.1|refseq:NP_731073.1|refseq:NP_731074.1|ensemblmetazoa:FBgn0267698(gene)|ensemblmetazoa:FBtr0081714(transcript)|ensemblmetazoa:FBtr0081715(transcript)|ensemblmetazoa:FBtr0081716(transcript)|ensemblmetazoa:FBtr0334539(transcript)|ensemblmetazoa:FBtr0334544(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019991"(septate junction assembly)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035072"(ecdysone-mediated induction of salivary gland cell autophagic cell death)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936 - - - comment:Pak was Myc tagged while Rac 2 was GST tagged in the experiment. taxid:-1(in vitro)|taxid:-1(In vitro) - 2003/11/18 2021/06/18 rogid:PNIBHOg5t2eu9wEta4DW1OboF0w7227 rogid:B88kI/CaRk7fc0eQ5+Y4jk4zWwc7227 intact-crc:5ECEC31219388117|rigid:2zmq2A2iIr8GlWOW6IUl8KKDxis false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VI13 uniprotkb:P40792 intact:EBI-74826|intact:EBI-123979|intact:EBI-466309|uniprotkb:Q24190|uniprotkb:Q24213|ensemblmetazoa:FBpp0081211|ensemblmetazoa:FBpp0081212|ensemblmetazoa:FBpp0081213|ensemblmetazoa:FBpp0306606|ensemblmetazoa:FBpp0306611 intact:EBI-74845|uniprotkb:Q9W0H7|ensemblmetazoa:FBpp0072614|ensemblmetazoa:FBpp0304252 psi-mi:pak_drome(display_long)|uniprotkb:Pak(gene name)|psi-mi:Pak(display_short)|uniprotkb:DPAK(gene name synonym)|uniprotkb:Dpak1(gene name synonym)|uniprotkb:CG10295(orf name) psi-mi:rac1_drome(display_long)|uniprotkb:Rac1(gene name)|psi-mi:Rac1(display_short)|uniprotkb:RacA(gene name synonym)|uniprotkb:CG2248(orf name) psi-mi:"MI:0018"(two hybrid) Newsome et al. (2000) pubmed:10847683 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-75913 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0267698|refseq:NP_001262309.1|refseq:NP_001262313.1|refseq:NP_524681.1|refseq:NP_731073.1|refseq:NP_731074.1|ensemblmetazoa:FBgn0267698(gene)|ensemblmetazoa:FBtr0081714(transcript)|ensemblmetazoa:FBtr0081715(transcript)|ensemblmetazoa:FBtr0081716(transcript)|ensemblmetazoa:FBtr0334539(transcript)|ensemblmetazoa:FBtr0334544(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007391"(dorsal closure)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019991"(septate junction assembly)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035072"(ecdysone-mediated induction of salivary gland cell autophagic cell death)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936 refseq:NP_476950.1|flybase:FBgn0010333|refseq:NP_001261247.1|ensemblmetazoa:FBgn0010333(gene)|ensemblmetazoa:FBtr0072730(transcript)|ensemblmetazoa:FBtr0331868(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002433"(immune response-regulating cell surface receptor signaling pathway involved in phagocytosis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007394"(dorsal closure, elongation of leading edge cells)|go:"GO:0007395"(dorsal closure, spreading of leading edge cells)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007516"(hemocyte development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007613"(memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0008258"(head involution)|go:"GO:0008347"(glial cell migration)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0016028"(rhabdomere)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016203"(muscle attachment)|go:"GO:0016358"(dendrite development)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035010"(encapsulation of foreign target)|go:"GO:0035011"(melanotic encapsulation of foreign target)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0035320"(imaginal disc-derived wing hair site selection)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048615"("embryonic anterior midgut (ectodermal) morphogenesis")|go:"GO:0048675"(axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0055001"(muscle cell development)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097206"(nephrocyte filtration)|go:"GO:0110125"(negative regulation of myotube cell migration)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1903391"(regulation of adherens junction organization)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-114604|reactome:R-DME-1433557|reactome:R-DME-193648|reactome:R-DME-2029482|reactome:R-DME-2871796|reactome:R-DME-350376|reactome:R-DME-376172|reactome:R-DME-389359|reactome:R-DME-3928662|reactome:R-DME-3928664|reactome:R-DME-3928665|reactome:R-DME-399954|reactome:R-DME-4086400|reactome:R-DME-4420097|reactome:R-DME-445144|reactome:R-DME-5218920|reactome:R-DME-5625740|reactome:R-DME-5627123|reactome:R-DME-5663213|reactome:R-DME-5687128|reactome:R-DME-6798695|reactome:R-DME-8849471|reactome:R-DME-9013149|reactome:R-DME-9013404|reactome:R-DME-9013407|reactome:R-DME-9706019|reactome:R-DME-983231 - - - comment:Interaction observed only in the presence of GTP-bound form of Rac1. taxid:-1(in vitro)|taxid:-1(In vitro) - 2003/11/18 2021/06/18 rogid:B88kI/CaRk7fc0eQ5+Y4jk4zWwc7227 rogid:nVrsdRuWmYjJp67rd4Es0mFDuUU7227 intact-crc:F21F7E5BECF2A987|rigid:loWbXxe2q6dYxzB4+nQIlLV/SHE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)