#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UKS6	uniprotkb:Q13444	intact:EBI-77926|ensembl:ENSP00000298838|ensembl:ENSP00000440945|uniprotkb:A6NH84|uniprotkb:Q9H331|uniprotkb:Q9NWV9	intact:EBI-77818|uniprotkb:Q5SR69|ensembl:ENSP00000349436|uniprotkb:Q13493|uniprotkb:Q53XQ0|uniprotkb:Q96C78|uniprotkb:B3KQU5|uniprotkb:Q5SR68|uniprotkb:Q6R267|uniprotkb:Q71S61|uniprotkb:Q71S62|uniprotkb:Q71S63|uniprotkb:Q71S64|uniprotkb:Q71S65|uniprotkb:Q71S66|uniprotkb:Q71S67|uniprotkb:Q71S68|uniprotkb:Q71S69|uniprotkb:B4DLB5|uniprotkb:E9PN65|uniprotkb:B4DMH8|uniprotkb:U3KQL5	psi-mi:pacn3_human(display_long)|uniprotkb:PACSIN3(gene name)|psi-mi:PACSIN3(display_short)|uniprotkb:SH3 domain-containing protein 6511(gene name synonym)	psi-mi:ada15_human(display_long)|uniprotkb:ADAM15(gene name)|psi-mi:ADAM15(display_short)|uniprotkb:MDC15(gene name synonym)|uniprotkb:Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15(gene name synonym)|uniprotkb:Metalloprotease RGD disintegrin protein(gene name synonym)|uniprotkb:Metargidin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Howard et al. (1999)	pubmed:10531379|mint:MINT-5211924	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-77845	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008289"(lipid binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028523|interpro:IPR031160|interpro:IPR036028|mint:Q9UKS6|reactome:R-HSA-8856828|ensembl:ENSG00000165912(gene)|ensembl:ENST00000298838(transcript)|ensembl:ENST00000539589(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|refseq:NP_001171903.1|refseq:NP_001171904.1|refseq:NP_057307.2	ensembl:ENSG00000143537(gene)|ensembl:ENST00000356955(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002418"(immune response to tumor cell)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0042246"(tissue regeneration)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1990910"(response to hypobaric hypoxia)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR024079|interpro:IPR033605|interpro:IPR034027|interpro:IPR036436|mint:Q13444|reactome:R-HSA-1474228|reactome:R-HSA-8941237|refseq:NP_003806.3|refseq:NP_997074.1|refseq:NP_997077.1|refseq:NP_997078.1|refseq:NP_997079.1|refseq:NP_997080.1|refseq:NP_001248394.1|refseq:NP_001248393.1|refseq:NP_001248395.1	-	-	-	comment:used ADAM15 cytoplasmic domain|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2003/11/28	2014/10/16	rogid:kxgltMI3NBu8k0ihTG8Nce63cQE9606	rogid:wMQLjw9xepknd94XZXdmwnmEwhc9606	intact-crc:F0FFE90C1B8585FF|rigid:NjDBpPoGxU3E94niRX+bkPTK2LI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y5X1	uniprotkb:Q13444	intact:EBI-77848|ensembl:ENSP00000376024|ensembl:ENSP00000506326|uniprotkb:Q9BSI7|uniprotkb:Q9BVM1|uniprotkb:Q9UJH6|uniprotkb:Q9UP20	intact:EBI-77818|uniprotkb:Q5SR69|ensembl:ENSP00000349436|uniprotkb:Q13493|uniprotkb:Q53XQ0|uniprotkb:Q96C78|uniprotkb:B3KQU5|uniprotkb:Q5SR68|uniprotkb:Q6R267|uniprotkb:Q71S61|uniprotkb:Q71S62|uniprotkb:Q71S63|uniprotkb:Q71S64|uniprotkb:Q71S65|uniprotkb:Q71S66|uniprotkb:Q71S67|uniprotkb:Q71S68|uniprotkb:Q71S69|uniprotkb:B4DLB5|uniprotkb:E9PN65|uniprotkb:B4DMH8|uniprotkb:U3KQL5	psi-mi:snx9_human(display_long)|uniprotkb:SNX9(gene name)|psi-mi:SNX9(display_short)|uniprotkb:SH3PX1(gene name synonym)|uniprotkb:SH3PXD3A(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 3A(gene name synonym)	psi-mi:ada15_human(display_long)|uniprotkb:ADAM15(gene name)|psi-mi:ADAM15(display_short)|uniprotkb:MDC15(gene name synonym)|uniprotkb:Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15(gene name synonym)|uniprotkb:Metalloprotease RGD disintegrin protein(gene name synonym)|uniprotkb:Metargidin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Howard et al. (1999)	pubmed:10531379|mint:MINT-5211924	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-77862	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000130340(gene)|ensembl:ENST00000392185(transcript)|ensembl:ENST00000679814(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001726"(ruffle)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032437"(cuticular plate)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR028644|interpro:IPR035558|interpro:IPR036028|interpro:IPR036871|interpro:IPR037425|interpro:IPR037426|mint:Q9Y5X1|rcsb pdb:2RAI|rcsb pdb:2RAJ|rcsb pdb:2RAK|rcsb pdb:3DYT|rcsb pdb:3DYU|rcsb pdb:3LGE|reactome:R-HSA-432722|reactome:R-HSA-8856828|refseq:NP_057308.1|dip:DIP-30997N	ensembl:ENSG00000143537(gene)|ensembl:ENST00000356955(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002418"(immune response to tumor cell)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0042246"(tissue regeneration)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1990910"(response to hypobaric hypoxia)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR024079|interpro:IPR033605|interpro:IPR034027|interpro:IPR036436|mint:Q13444|reactome:R-HSA-1474228|reactome:R-HSA-8941237|refseq:NP_003806.3|refseq:NP_997074.1|refseq:NP_997077.1|refseq:NP_997078.1|refseq:NP_997079.1|refseq:NP_997080.1|refseq:NP_001248394.1|refseq:NP_001248393.1|refseq:NP_001248395.1	-	-	-	comment:used ADAM15 cytoplasmic domain|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2003/11/28	2014/10/16	rogid:qtqmMew2psrK6OJPAOWQGTVmNJA9606	rogid:wMQLjw9xepknd94XZXdmwnmEwhc9606	intact-crc:433440B84FE8D526|rigid:oKZSabexIqr7KZRNAA5FgKCMNbA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13444	uniprotkb:Q96R06	intact:EBI-77818|uniprotkb:Q5SR69|ensembl:ENSP00000349436|uniprotkb:Q13493|uniprotkb:Q53XQ0|uniprotkb:Q96C78|uniprotkb:B3KQU5|uniprotkb:Q5SR68|uniprotkb:Q6R267|uniprotkb:Q71S61|uniprotkb:Q71S62|uniprotkb:Q71S63|uniprotkb:Q71S64|uniprotkb:Q71S65|uniprotkb:Q71S66|uniprotkb:Q71S67|uniprotkb:Q71S68|uniprotkb:Q71S69|uniprotkb:B4DLB5|uniprotkb:E9PN65|uniprotkb:B4DMH8|uniprotkb:U3KQL5	intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300	psi-mi:ada15_human(display_long)|uniprotkb:ADAM15(gene name)|psi-mi:ADAM15(display_short)|uniprotkb:MDC15(gene name synonym)|uniprotkb:Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15(gene name synonym)|uniprotkb:Metalloprotease RGD disintegrin protein(gene name synonym)|uniprotkb:Metargidin(gene name synonym)	psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Howard et al. (1999)	pubmed:10531379|mint:MINT-5211924	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-77871	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143537(gene)|ensembl:ENST00000356955(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002418"(immune response to tumor cell)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0042246"(tissue regeneration)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1990910"(response to hypobaric hypoxia)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR024079|interpro:IPR033605|interpro:IPR034027|interpro:IPR036436|mint:Q13444|reactome:R-HSA-1474228|reactome:R-HSA-8941237|refseq:NP_003806.3|refseq:NP_997074.1|refseq:NP_997077.1|refseq:NP_997078.1|refseq:NP_997079.1|refseq:NP_997080.1|refseq:NP_001248394.1|refseq:NP_001248393.1|refseq:NP_001248395.1	refseq:NP_006452.3|ensembl:ENSP00000323300|ensembl:ENSG00000076382(gene)|ensembl:ENST00000321765(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N	-	-	-	comment:used ADAM15 cytoplasmic domain|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2003/11/28	2014/10/16	rogid:wMQLjw9xepknd94XZXdmwnmEwhc9606	rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606	intact-crc:C202321850B78E57|rigid:GKcLiBYkS5IpdQmaNxrsswJDJak	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13444	uniprotkb:Q9UI95	intact:EBI-77818|uniprotkb:Q5SR69|ensembl:ENSP00000349436|uniprotkb:Q13493|uniprotkb:Q53XQ0|uniprotkb:Q96C78|uniprotkb:B3KQU5|uniprotkb:Q5SR68|uniprotkb:Q6R267|uniprotkb:Q71S61|uniprotkb:Q71S62|uniprotkb:Q71S63|uniprotkb:Q71S64|uniprotkb:Q71S65|uniprotkb:Q71S66|uniprotkb:Q71S67|uniprotkb:Q71S68|uniprotkb:Q71S69|uniprotkb:B4DLB5|uniprotkb:E9PN65|uniprotkb:B4DMH8|uniprotkb:U3KQL5	intact:EBI-77889|ensembl:ENSP00000235310|ensembl:ENSP00000365855|ensembl:ENSP00000365882|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3	psi-mi:ada15_human(display_long)|uniprotkb:ADAM15(gene name)|psi-mi:ADAM15(display_short)|uniprotkb:MDC15(gene name synonym)|uniprotkb:Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15(gene name synonym)|uniprotkb:Metalloprotease RGD disintegrin protein(gene name synonym)|uniprotkb:Metargidin(gene name synonym)	psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Howard et al. (1999)	pubmed:10531379|mint:MINT-5211924	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-77900	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143537(gene)|ensembl:ENST00000356955(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002418"(immune response to tumor cell)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0042246"(tissue regeneration)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1990910"(response to hypobaric hypoxia)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR024079|interpro:IPR033605|interpro:IPR034027|interpro:IPR036436|mint:Q13444|reactome:R-HSA-1474228|reactome:R-HSA-8941237|refseq:NP_003806.3|refseq:NP_997074.1|refseq:NP_997077.1|refseq:NP_997078.1|refseq:NP_997079.1|refseq:NP_997080.1|refseq:NP_001248394.1|refseq:NP_001248393.1|refseq:NP_001248395.1	ensembl:ENSG00000116670(gene)|ensembl:ENST00000235310(transcript)|ensembl:ENST00000376667(transcript)|ensembl:ENST00000376692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016035"(zeta DNA polymerase complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042772"(DNA damage response, signal transduction resulting in transcription)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS0|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1	-	-	-	comment:used  ADAM15 cytoplasmic domain|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2003/11/28	2014/10/16	rogid:wMQLjw9xepknd94XZXdmwnmEwhc9606	rogid:KBeawMhcP3iXUel74pUDl85A/vw9606	intact-crc:5A427B5130199EC1|rigid:AadHQEjgpFaat2sP9U2qenNAER4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13444	uniprotkb:Q99962	intact:EBI-77818|uniprotkb:Q5SR69|ensembl:ENSP00000349436|uniprotkb:Q13493|uniprotkb:Q53XQ0|uniprotkb:Q96C78|uniprotkb:B3KQU5|uniprotkb:Q5SR68|uniprotkb:Q6R267|uniprotkb:Q71S61|uniprotkb:Q71S62|uniprotkb:Q71S63|uniprotkb:Q71S64|uniprotkb:Q71S65|uniprotkb:Q71S66|uniprotkb:Q71S67|uniprotkb:Q71S68|uniprotkb:Q71S69|uniprotkb:B4DLB5|uniprotkb:E9PN65|uniprotkb:B4DMH8|uniprotkb:U3KQL5	intact:EBI-77938|ensembl:ENSP00000369981|uniprotkb:Q9NQK5|uniprotkb:B2R618	psi-mi:ada15_human(display_long)|uniprotkb:ADAM15(gene name)|psi-mi:ADAM15(display_short)|uniprotkb:MDC15(gene name synonym)|uniprotkb:Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15(gene name synonym)|uniprotkb:Metalloprotease RGD disintegrin protein(gene name synonym)|uniprotkb:Metargidin(gene name synonym)	psi-mi:sh3g2_human(display_long)|uniprotkb:SH3GL2(gene name)|psi-mi:SH3GL2(display_short)|uniprotkb:CNSA2(gene name synonym)|uniprotkb:SH3D2A(gene name synonym)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:EEN-B1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Howard et al. (1999)	pubmed:10531379|mint:MINT-5211924	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-77950	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143537(gene)|ensembl:ENST00000356955(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002418"(immune response to tumor cell)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0042246"(tissue regeneration)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1990910"(response to hypobaric hypoxia)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR024079|interpro:IPR033605|interpro:IPR034027|interpro:IPR036436|mint:Q13444|reactome:R-HSA-1474228|reactome:R-HSA-8941237|refseq:NP_003806.3|refseq:NP_997074.1|refseq:NP_997077.1|refseq:NP_997078.1|refseq:NP_997079.1|refseq:NP_997080.1|refseq:NP_001248394.1|refseq:NP_001248393.1|refseq:NP_001248395.1	go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035824|interpro:IPR036028|mint:Q99962|rcsb pdb:1X03|rcsb pdb:1X04|rcsb pdb:2D4C|rcsb pdb:2DBM|reactome:R-HSA-177504|reactome:R-HSA-182971|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|ensembl:ENSG00000107295(gene)|ensembl:ENST00000380607(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|refseq:NP_003017.1|dip:DIP-30996N	-	-	-	comment:used ADAM15 cytoplasmic domain|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2003/11/28	2014/10/16	rogid:wMQLjw9xepknd94XZXdmwnmEwhc9606	rogid:mAk7M0s5Dd2Qoa/e1rPYvVcV3xs9606	intact-crc:55D0EF296B195042|rigid:dfXO6SpwCDxNjtpJeHKLa3RzgIE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13443	uniprotkb:Q9UI95	intact:EBI-77903|uniprotkb:B7ZLN7|ensembl:ENSP00000419446|uniprotkb:Q10718|uniprotkb:Q8NFM6	intact:EBI-77889|ensembl:ENSP00000235310|ensembl:ENSP00000365855|ensembl:ENSP00000365882|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3	psi-mi:adam9_human(display_long)|uniprotkb:ADAM9(gene name)|psi-mi:ADAM9(display_short)|uniprotkb:KIAA0021(gene name synonym)|uniprotkb:MCMP(gene name synonym)|uniprotkb:MDC9(gene name synonym)|uniprotkb:Myeloma cell metalloproteinase(gene name synonym)|uniprotkb:Meltrin-gamma(gene name synonym)|uniprotkb:Cellular disintegrin-related protein(gene name synonym)|uniprotkb:Metalloprotease/disintegrin/cysteine-rich protein 9(gene name synonym)|uniprotkb:MLTNG(gene name synonym)	psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Howard et al. (1999)	pubmed:10531379|mint:MINT-5211924	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-77923	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007160"(cell-matrix adhesion)|ensembl:ENSG00000168615(gene)|ensembl:ENST00000487273(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016485"(protein processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0031293"(membrane protein intracellular domain proteolysis)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0042117"(monocyte activation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043236"(laminin binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0097327"(response to antineoplastic agent)|go:"GO:1902945"(metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|rcsb pdb:1M1V|reactome:R-HSA-1442490|refseq:NP_003807.1	ensembl:ENSG00000116670(gene)|ensembl:ENST00000235310(transcript)|ensembl:ENST00000376667(transcript)|ensembl:ENST00000376692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016035"(zeta DNA polymerase complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042772"(DNA damage response, signal transduction resulting in transcription)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS0|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1	-	-	-	comment:ADAM9 cytoplasmic domain used as bait|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2003/11/28	2014/10/16	rogid:cgdFZLtfiaqZ+oJvDARR1AbFA+I9606	rogid:KBeawMhcP3iXUel74pUDl85A/vw9606	intact-crc:3B236E9AF9A1FB39|rigid:J0DAj4x6CMTRSQpo/EDZUJGtf5o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13443	uniprotkb:Q9UKS6	intact:EBI-77903|uniprotkb:B7ZLN7|ensembl:ENSP00000419446|uniprotkb:Q10718|uniprotkb:Q8NFM6	intact:EBI-77926|ensembl:ENSP00000298838|ensembl:ENSP00000440945|uniprotkb:A6NH84|uniprotkb:Q9H331|uniprotkb:Q9NWV9	psi-mi:adam9_human(display_long)|uniprotkb:ADAM9(gene name)|psi-mi:ADAM9(display_short)|uniprotkb:KIAA0021(gene name synonym)|uniprotkb:MCMP(gene name synonym)|uniprotkb:MDC9(gene name synonym)|uniprotkb:Myeloma cell metalloproteinase(gene name synonym)|uniprotkb:Meltrin-gamma(gene name synonym)|uniprotkb:Cellular disintegrin-related protein(gene name synonym)|uniprotkb:Metalloprotease/disintegrin/cysteine-rich protein 9(gene name synonym)|uniprotkb:MLTNG(gene name synonym)	psi-mi:pacn3_human(display_long)|uniprotkb:PACSIN3(gene name)|psi-mi:PACSIN3(display_short)|uniprotkb:SH3 domain-containing protein 6511(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Howard et al. (1999)	pubmed:10531379|mint:MINT-5211924	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-77935	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007160"(cell-matrix adhesion)|ensembl:ENSG00000168615(gene)|ensembl:ENST00000487273(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016485"(protein processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0031293"(membrane protein intracellular domain proteolysis)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0042117"(monocyte activation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043236"(laminin binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0097327"(response to antineoplastic agent)|go:"GO:1902945"(metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|rcsb pdb:1M1V|reactome:R-HSA-1442490|refseq:NP_003807.1	go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008289"(lipid binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028523|interpro:IPR031160|interpro:IPR036028|mint:Q9UKS6|reactome:R-HSA-8856828|ensembl:ENSG00000165912(gene)|ensembl:ENST00000298838(transcript)|ensembl:ENST00000539589(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|refseq:NP_001171903.1|refseq:NP_001171904.1|refseq:NP_057307.2	-	-	-	comment:used ADAM9 cytoplasmic domain|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2003/11/28	2014/10/16	rogid:cgdFZLtfiaqZ+oJvDARR1AbFA+I9606	rogid:kxgltMI3NBu8k0ihTG8Nce63cQE9606	intact-crc:84095D3E75010508|rigid:J7XxgD9UNQDi/xQ7CWwerMjOXcY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13443	uniprotkb:Q99962	intact:EBI-77903|uniprotkb:B7ZLN7|ensembl:ENSP00000419446|uniprotkb:Q10718|uniprotkb:Q8NFM6	intact:EBI-77938|ensembl:ENSP00000369981|uniprotkb:Q9NQK5|uniprotkb:B2R618	psi-mi:adam9_human(display_long)|uniprotkb:ADAM9(gene name)|psi-mi:ADAM9(display_short)|uniprotkb:KIAA0021(gene name synonym)|uniprotkb:MCMP(gene name synonym)|uniprotkb:MDC9(gene name synonym)|uniprotkb:Myeloma cell metalloproteinase(gene name synonym)|uniprotkb:Meltrin-gamma(gene name synonym)|uniprotkb:Cellular disintegrin-related protein(gene name synonym)|uniprotkb:Metalloprotease/disintegrin/cysteine-rich protein 9(gene name synonym)|uniprotkb:MLTNG(gene name synonym)	psi-mi:sh3g2_human(display_long)|uniprotkb:SH3GL2(gene name)|psi-mi:SH3GL2(display_short)|uniprotkb:CNSA2(gene name synonym)|uniprotkb:SH3D2A(gene name synonym)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:EEN-B1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Howard et al. (1999)	pubmed:10531379|mint:MINT-5211924	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-77953	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007160"(cell-matrix adhesion)|ensembl:ENSG00000168615(gene)|ensembl:ENST00000487273(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016485"(protein processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0031293"(membrane protein intracellular domain proteolysis)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0042117"(monocyte activation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043236"(laminin binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0097327"(response to antineoplastic agent)|go:"GO:1902945"(metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|rcsb pdb:1M1V|reactome:R-HSA-1442490|refseq:NP_003807.1	go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035824|interpro:IPR036028|mint:Q99962|rcsb pdb:1X03|rcsb pdb:1X04|rcsb pdb:2D4C|rcsb pdb:2DBM|reactome:R-HSA-177504|reactome:R-HSA-182971|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|ensembl:ENSG00000107295(gene)|ensembl:ENST00000380607(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|refseq:NP_003017.1|dip:DIP-30996N	-	-	-	dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2003/11/28	2014/10/16	rogid:cgdFZLtfiaqZ+oJvDARR1AbFA+I9606	rogid:mAk7M0s5Dd2Qoa/e1rPYvVcV3xs9606	intact-crc:46E2B3B209F1F0A9|rigid:Y2dZFEPdWng/91Jk/RvKkiPmgfU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99JB8	uniprotkb:O88839	intact:EBI-77834|ensembl:ENSMUSP00000028694|ensembl:ENSMUSP00000054391|ensembl:ENSMUSP00000106981|ensembl:ENSMUSP00000129175|uniprotkb:Q9EQP9	intact:EBI-77874|ensembl:ENSMUSP00000029676|ensembl:ENSMUSP00000139147|uniprotkb:Q3U7C2|uniprotkb:Q8C7Z0|uniprotkb:Q91VS9|uniprotkb:Q9QYL2|uniprotkb:A4ZYV2|uniprotkb:Q3TDN7|uniprotkb:Q3UE21	psi-mi:pacn3_mouse(display_long)|uniprotkb:Pacsin3(gene name)|psi-mi:Pacsin3(display_short)	psi-mi:ada15_mouse(display_long)|uniprotkb:Adam15(gene name)|psi-mi:Adam15(display_short)|uniprotkb:Mdc15(gene name synonym)|uniprotkb:Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15(gene name synonym)|uniprotkb:Metalloprotease RGD disintegrin protein(gene name synonym)|uniprotkb:Metargidin(gene name synonym)|uniprotkb:AD56(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Howard et al. (1999)	pubmed:10531379|mint:MINT-5211924	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-77968	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000027257(gene)|ensembl:ENSMUST00000028694(transcript)|ensembl:ENSMUST00000059566(transcript)|ensembl:ENSMUST00000111349(transcript)|ensembl:ENSMUST00000168916(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008289"(lipid binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028523|interpro:IPR031160|interpro:IPR036028|mint:Q99JB8|rcsb pdb:3M3W|rcsb pdb:3QE6|rcsb pdb:3SYV|reactome:R-MMU-8856828|refseq:NP_083009.1|refseq:NP_112019.2|refseq:XP_006500487.1|refseq:XP_006500488.1|refseq:XP_006500490.1|refseq:XP_006500491.1|refseq:NP_001276606.1|refseq:NP_001276607.1	ensembl:ENSMUSG00000028041(gene)|ensembl:ENSMUST00000029676(transcript)|ensembl:ENSMUST00000184651(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002418"(immune response to tumor cell)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0042246"(tissue regeneration)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1990910"(response to hypobaric hypoxia)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR024079|interpro:IPR033605|interpro:IPR034027|interpro:IPR036436|mint:O88839|reactome:R-MMU-1474228|reactome:R-MMU-8941237|refseq:NP_001032811.2|refseq:NP_033744.1|ensembl:ENSMUSG00000028041|refseq:XP_006500981.1	-	-	-	dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	-	2003/11/28	2014/10/16	rogid:cm01D0WJAwAupYJ64NRxTeFC79U10090	rogid:FXZ6x4sYDNODovNUeNOydD13l5Y10090	intact-crc:881F0C25590420AD|rigid:03lA6HSC8ivwcu2m0mbTs5aNjb0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q61072	uniprotkb:Q99JB8	intact:EBI-77983|uniprotkb:E9QPP2|ensembl:ENSMUSP00000081048|uniprotkb:Q60618|uniprotkb:Q61853|uniprotkb:Q80U94	intact:EBI-77834|ensembl:ENSMUSP00000028694|ensembl:ENSMUSP00000054391|ensembl:ENSMUSP00000106981|ensembl:ENSMUSP00000129175|uniprotkb:Q9EQP9	psi-mi:adam9_mouse(display_long)|uniprotkb:Adam9(gene name)|psi-mi:Adam9(display_short)|uniprotkb:Kiaa0021(gene name synonym)|uniprotkb:Mdc9(gene name synonym)|uniprotkb:Mltng(gene name synonym)|uniprotkb:Metalloprotease/disintegrin/cysteine-rich protein 9(gene name synonym)|uniprotkb:Myeloma cell metalloproteinase(gene name synonym)|uniprotkb:Meltrin-gamma(gene name synonym)	psi-mi:pacn3_mouse(display_long)|uniprotkb:Pacsin3(gene name)|psi-mi:Pacsin3(display_short)	psi-mi:"MI:0019"(coimmunoprecipitation)	Howard et al. (1999)	pubmed:10531379|mint:MINT-5211924	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-78003	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000031555(gene)|ensembl:ENSMUST00000084035(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016485"(protein processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0031293"(membrane protein intracellular domain proteolysis)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042117"(monocyte activation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043236"(laminin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902945"(metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|refseq:NP_031430.2	ensembl:ENSMUSG00000027257(gene)|ensembl:ENSMUST00000028694(transcript)|ensembl:ENSMUST00000059566(transcript)|ensembl:ENSMUST00000111349(transcript)|ensembl:ENSMUST00000168916(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008289"(lipid binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028523|interpro:IPR031160|interpro:IPR036028|mint:Q99JB8|rcsb pdb:3M3W|rcsb pdb:3QE6|rcsb pdb:3SYV|reactome:R-MMU-8856828|refseq:NP_083009.1|refseq:NP_112019.2|refseq:XP_006500487.1|refseq:XP_006500488.1|refseq:XP_006500490.1|refseq:XP_006500491.1|refseq:NP_001276606.1|refseq:NP_001276607.1	-	-	-	dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	-	2003/11/28	2014/10/16	rogid:GSTKev8sg5lfwupVNEpPkPhFxHA10090	rogid:cm01D0WJAwAupYJ64NRxTeFC79U10090	intact-crc:6AA8D4E718863E16|rigid:wHi8AV2kM3Xe2cE4o0SFh18A8gc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q61072	uniprotkb:Q62420	intact:EBI-77983|uniprotkb:E9QPP2|ensembl:ENSMUSP00000081048|uniprotkb:Q60618|uniprotkb:Q61853|uniprotkb:Q80U94	intact:EBI-77971|ensembl:ENSMUSP00000030212|uniprotkb:Q3UTL7|uniprotkb:Q3UY49|uniprotkb:Q8BXS6|uniprotkb:Q8VBV1	psi-mi:adam9_mouse(display_long)|uniprotkb:Adam9(gene name)|psi-mi:Adam9(display_short)|uniprotkb:Kiaa0021(gene name synonym)|uniprotkb:Mdc9(gene name synonym)|uniprotkb:Mltng(gene name synonym)|uniprotkb:Metalloprotease/disintegrin/cysteine-rich protein 9(gene name synonym)|uniprotkb:Myeloma cell metalloproteinase(gene name synonym)|uniprotkb:Meltrin-gamma(gene name synonym)	psi-mi:sh3g2_mouse(display_long)|uniprotkb:Sh3gl2(gene name)|psi-mi:Sh3gl2(display_short)|uniprotkb:Sh3d2a(gene name synonym)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:Een1(gene name synonym)|uniprotkb:SH3p4(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Howard et al. (1999)	pubmed:10531379|mint:MINT-5211924	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-78022	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000031555(gene)|ensembl:ENSMUST00000084035(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016485"(protein processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0031293"(membrane protein intracellular domain proteolysis)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042117"(monocyte activation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043236"(laminin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902945"(metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|refseq:NP_031430.2	interpro:IPR035824|interpro:IPR036028|mint:Q62420|rcsb pdb:1ZWW|reactome:R-MMU-177504|reactome:R-MMU-182971|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-437239|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0008022"(protein C-terminus binding)|ensembl:ENSMUSG00000028488(gene)|ensembl:ENSMUST00000030212(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|refseq:NP_062408.2|dip:DIP-30992N	-	-	-	dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	-	2003/11/28	2014/10/16	rogid:GSTKev8sg5lfwupVNEpPkPhFxHA10090	rogid:hAkiLVjGXejkjd5pRcuq9wVXrfk10090	intact-crc:BDC7FAEFA31CB122|rigid:mKYLGQbSogyU1jt1cioPq5bQiSY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q62420	uniprotkb:O88839	intact:EBI-77971|ensembl:ENSMUSP00000030212|uniprotkb:Q3UTL7|uniprotkb:Q3UY49|uniprotkb:Q8BXS6|uniprotkb:Q8VBV1	intact:EBI-77874|ensembl:ENSMUSP00000029676|ensembl:ENSMUSP00000139147|uniprotkb:Q3U7C2|uniprotkb:Q8C7Z0|uniprotkb:Q91VS9|uniprotkb:Q9QYL2|uniprotkb:A4ZYV2|uniprotkb:Q3TDN7|uniprotkb:Q3UE21	psi-mi:sh3g2_mouse(display_long)|uniprotkb:Sh3gl2(gene name)|psi-mi:Sh3gl2(display_short)|uniprotkb:Sh3d2a(gene name synonym)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:Een1(gene name synonym)|uniprotkb:SH3p4(gene name synonym)	psi-mi:ada15_mouse(display_long)|uniprotkb:Adam15(gene name)|psi-mi:Adam15(display_short)|uniprotkb:Mdc15(gene name synonym)|uniprotkb:Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15(gene name synonym)|uniprotkb:Metalloprotease RGD disintegrin protein(gene name synonym)|uniprotkb:Metargidin(gene name synonym)|uniprotkb:AD56(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Howard et al. (1999)	pubmed:10531379|mint:MINT-5211924	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-77980	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR035824|interpro:IPR036028|mint:Q62420|rcsb pdb:1ZWW|reactome:R-MMU-177504|reactome:R-MMU-182971|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-437239|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0008022"(protein C-terminus binding)|ensembl:ENSMUSG00000028488(gene)|ensembl:ENSMUST00000030212(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|refseq:NP_062408.2|dip:DIP-30992N	ensembl:ENSMUSG00000028041(gene)|ensembl:ENSMUST00000029676(transcript)|ensembl:ENSMUST00000184651(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002418"(immune response to tumor cell)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0042246"(tissue regeneration)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1990910"(response to hypobaric hypoxia)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR024079|interpro:IPR033605|interpro:IPR034027|interpro:IPR036436|mint:O88839|reactome:R-MMU-1474228|reactome:R-MMU-8941237|refseq:NP_001032811.2|refseq:NP_033744.1|ensembl:ENSMUSG00000028041|refseq:XP_006500981.1	-	-	-	dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	-	2003/11/28	2014/10/16	rogid:hAkiLVjGXejkjd5pRcuq9wVXrfk10090	rogid:FXZ6x4sYDNODovNUeNOydD13l5Y10090	intact-crc:F6B5362DE29BBB9A|rigid:lFsWEU5HX7EGi0SyZ/l6WBKMoZg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13443	uniprotkb:Q9UKS6	intact:EBI-77903|uniprotkb:B7ZLN7|ensembl:ENSP00000419446|uniprotkb:Q10718|uniprotkb:Q8NFM6	intact:EBI-77926|ensembl:ENSP00000298838|ensembl:ENSP00000440945|uniprotkb:A6NH84|uniprotkb:Q9H331|uniprotkb:Q9NWV9	psi-mi:adam9_human(display_long)|uniprotkb:ADAM9(gene name)|psi-mi:ADAM9(display_short)|uniprotkb:KIAA0021(gene name synonym)|uniprotkb:MCMP(gene name synonym)|uniprotkb:MDC9(gene name synonym)|uniprotkb:Myeloma cell metalloproteinase(gene name synonym)|uniprotkb:Meltrin-gamma(gene name synonym)|uniprotkb:Cellular disintegrin-related protein(gene name synonym)|uniprotkb:Metalloprotease/disintegrin/cysteine-rich protein 9(gene name synonym)|uniprotkb:MLTNG(gene name synonym)	psi-mi:pacn3_human(display_long)|uniprotkb:PACSIN3(gene name)|psi-mi:PACSIN3(display_short)|uniprotkb:SH3 domain-containing protein 6511(gene name synonym)	psi-mi:"MI:0096"(pull down)	Howard et al. (1999)	pubmed:10531379|mint:MINT-5211924	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-78013	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007160"(cell-matrix adhesion)|ensembl:ENSG00000168615(gene)|ensembl:ENST00000487273(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016485"(protein processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0031293"(membrane protein intracellular domain proteolysis)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0042117"(monocyte activation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043236"(laminin binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0097327"(response to antineoplastic agent)|go:"GO:1902945"(metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|rcsb pdb:1M1V|reactome:R-HSA-1442490|refseq:NP_003807.1	go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008289"(lipid binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028523|interpro:IPR031160|interpro:IPR036028|mint:Q9UKS6|reactome:R-HSA-8856828|ensembl:ENSG00000165912(gene)|ensembl:ENST00000298838(transcript)|ensembl:ENST00000539589(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|refseq:NP_001171903.1|refseq:NP_001171904.1|refseq:NP_057307.2	-	-	-	comment:ADAM9 expressed as GST fusion in Ecoli|comment:PACSIN3 expressed as His/T7-tagged in Ecoli|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/11/28	2014/10/16	rogid:cgdFZLtfiaqZ+oJvDARR1AbFA+I9606	rogid:kxgltMI3NBu8k0ihTG8Nce63cQE9606	intact-crc:3AB564A7BF44547E|rigid:J7XxgD9UNQDi/xQ7CWwerMjOXcY	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q13444	uniprotkb:Q9UKS6	intact:EBI-77818|uniprotkb:Q5SR69|ensembl:ENSP00000349436|uniprotkb:Q13493|uniprotkb:Q53XQ0|uniprotkb:Q96C78|uniprotkb:B3KQU5|uniprotkb:Q5SR68|uniprotkb:Q6R267|uniprotkb:Q71S61|uniprotkb:Q71S62|uniprotkb:Q71S63|uniprotkb:Q71S64|uniprotkb:Q71S65|uniprotkb:Q71S66|uniprotkb:Q71S67|uniprotkb:Q71S68|uniprotkb:Q71S69|uniprotkb:B4DLB5|uniprotkb:E9PN65|uniprotkb:B4DMH8|uniprotkb:U3KQL5	intact:EBI-77926|ensembl:ENSP00000298838|ensembl:ENSP00000440945|uniprotkb:A6NH84|uniprotkb:Q9H331|uniprotkb:Q9NWV9	psi-mi:ada15_human(display_long)|uniprotkb:ADAM15(gene name)|psi-mi:ADAM15(display_short)|uniprotkb:MDC15(gene name synonym)|uniprotkb:Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15(gene name synonym)|uniprotkb:Metalloprotease RGD disintegrin protein(gene name synonym)|uniprotkb:Metargidin(gene name synonym)	psi-mi:pacn3_human(display_long)|uniprotkb:PACSIN3(gene name)|psi-mi:PACSIN3(display_short)|uniprotkb:SH3 domain-containing protein 6511(gene name synonym)	psi-mi:"MI:0096"(pull down)	Howard et al. (1999)	pubmed:10531379|mint:MINT-5211924	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-78019	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143537(gene)|ensembl:ENST00000356955(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002418"(immune response to tumor cell)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0042246"(tissue regeneration)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1990910"(response to hypobaric hypoxia)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR024079|interpro:IPR033605|interpro:IPR034027|interpro:IPR036436|mint:Q13444|reactome:R-HSA-1474228|reactome:R-HSA-8941237|refseq:NP_003806.3|refseq:NP_997074.1|refseq:NP_997077.1|refseq:NP_997078.1|refseq:NP_997079.1|refseq:NP_997080.1|refseq:NP_001248394.1|refseq:NP_001248393.1|refseq:NP_001248395.1	go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008289"(lipid binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028523|interpro:IPR031160|interpro:IPR036028|mint:Q9UKS6|reactome:R-HSA-8856828|ensembl:ENSG00000165912(gene)|ensembl:ENST00000298838(transcript)|ensembl:ENST00000539589(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|refseq:NP_001171903.1|refseq:NP_001171904.1|refseq:NP_057307.2	-	-	-	comment:ADAM15 expresses as GST fusion in Ecoli|comment:PACSIN3 expressed as His/T7-tagged in Ecoli|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/11/28	2014/10/16	rogid:wMQLjw9xepknd94XZXdmwnmEwhc9606	rogid:kxgltMI3NBu8k0ihTG8Nce63cQE9606	intact-crc:4443B7CE1DF58F88|rigid:NjDBpPoGxU3E94niRX+bkPTK2LI	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q99962	uniprotkb:Q13443	intact:EBI-77938|ensembl:ENSP00000369981|uniprotkb:Q9NQK5|uniprotkb:B2R618	intact:EBI-77903|uniprotkb:B7ZLN7|ensembl:ENSP00000419446|uniprotkb:Q10718|uniprotkb:Q8NFM6	psi-mi:sh3g2_human(display_long)|uniprotkb:SH3GL2(gene name)|psi-mi:SH3GL2(display_short)|uniprotkb:CNSA2(gene name synonym)|uniprotkb:SH3D2A(gene name synonym)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:EEN-B1(gene name synonym)	psi-mi:adam9_human(display_long)|uniprotkb:ADAM9(gene name)|psi-mi:ADAM9(display_short)|uniprotkb:KIAA0021(gene name synonym)|uniprotkb:MCMP(gene name synonym)|uniprotkb:MDC9(gene name synonym)|uniprotkb:Myeloma cell metalloproteinase(gene name synonym)|uniprotkb:Meltrin-gamma(gene name synonym)|uniprotkb:Cellular disintegrin-related protein(gene name synonym)|uniprotkb:Metalloprotease/disintegrin/cysteine-rich protein 9(gene name synonym)|uniprotkb:MLTNG(gene name synonym)	psi-mi:"MI:0096"(pull down)	Howard et al. (1999)	pubmed:10531379|mint:MINT-5211924	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-78026	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035824|interpro:IPR036028|mint:Q99962|rcsb pdb:1X03|rcsb pdb:1X04|rcsb pdb:2D4C|rcsb pdb:2DBM|reactome:R-HSA-177504|reactome:R-HSA-182971|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|ensembl:ENSG00000107295(gene)|ensembl:ENST00000380607(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|refseq:NP_003017.1|dip:DIP-30996N	go:"GO:0007160"(cell-matrix adhesion)|ensembl:ENSG00000168615(gene)|ensembl:ENST00000487273(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016485"(protein processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0031293"(membrane protein intracellular domain proteolysis)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0042117"(monocyte activation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043236"(laminin binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0097327"(response to antineoplastic agent)|go:"GO:1902945"(metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|rcsb pdb:1M1V|reactome:R-HSA-1442490|refseq:NP_003807.1	-	-	-	comment:ADAM9 expressed as GST fusion in Ecoli|comment:SH3GL2 expressed as His/T7-tagged in Ecoli|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/11/28	2014/10/16	rogid:mAk7M0s5Dd2Qoa/e1rPYvVcV3xs9606	rogid:cgdFZLtfiaqZ+oJvDARR1AbFA+I9606	intact-crc:CE953DAD51AAE086|rigid:Y2dZFEPdWng/91Jk/RvKkiPmgfU	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q13444	uniprotkb:Q99962	intact:EBI-77818|uniprotkb:Q5SR69|ensembl:ENSP00000349436|uniprotkb:Q13493|uniprotkb:Q53XQ0|uniprotkb:Q96C78|uniprotkb:B3KQU5|uniprotkb:Q5SR68|uniprotkb:Q6R267|uniprotkb:Q71S61|uniprotkb:Q71S62|uniprotkb:Q71S63|uniprotkb:Q71S64|uniprotkb:Q71S65|uniprotkb:Q71S66|uniprotkb:Q71S67|uniprotkb:Q71S68|uniprotkb:Q71S69|uniprotkb:B4DLB5|uniprotkb:E9PN65|uniprotkb:B4DMH8|uniprotkb:U3KQL5	intact:EBI-77938|ensembl:ENSP00000369981|uniprotkb:Q9NQK5|uniprotkb:B2R618	psi-mi:ada15_human(display_long)|uniprotkb:ADAM15(gene name)|psi-mi:ADAM15(display_short)|uniprotkb:MDC15(gene name synonym)|uniprotkb:Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15(gene name synonym)|uniprotkb:Metalloprotease RGD disintegrin protein(gene name synonym)|uniprotkb:Metargidin(gene name synonym)	psi-mi:sh3g2_human(display_long)|uniprotkb:SH3GL2(gene name)|psi-mi:SH3GL2(display_short)|uniprotkb:CNSA2(gene name synonym)|uniprotkb:SH3D2A(gene name synonym)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:EEN-B1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Howard et al. (1999)	pubmed:10531379|mint:MINT-5211924	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-78016	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143537(gene)|ensembl:ENST00000356955(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002418"(immune response to tumor cell)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0042246"(tissue regeneration)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1990910"(response to hypobaric hypoxia)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR024079|interpro:IPR033605|interpro:IPR034027|interpro:IPR036436|mint:Q13444|reactome:R-HSA-1474228|reactome:R-HSA-8941237|refseq:NP_003806.3|refseq:NP_997074.1|refseq:NP_997077.1|refseq:NP_997078.1|refseq:NP_997079.1|refseq:NP_997080.1|refseq:NP_001248394.1|refseq:NP_001248393.1|refseq:NP_001248395.1	go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035824|interpro:IPR036028|mint:Q99962|rcsb pdb:1X03|rcsb pdb:1X04|rcsb pdb:2D4C|rcsb pdb:2DBM|reactome:R-HSA-177504|reactome:R-HSA-182971|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|ensembl:ENSG00000107295(gene)|ensembl:ENST00000380607(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|refseq:NP_003017.1|dip:DIP-30996N	-	-	-	comment:ADAM15 expressed as GST fusion in Ecoli|comment:SH3GL2 expressed as His-T7-tagged in Ecoli|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2003/11/28	2014/10/16	rogid:wMQLjw9xepknd94XZXdmwnmEwhc9606	rogid:mAk7M0s5Dd2Qoa/e1rPYvVcV3xs9606	intact-crc:DE53714B29093870|rigid:dfXO6SpwCDxNjtpJeHKLa3RzgIE	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)