#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P97837 uniprotkb:Q9WV48 intact:EBI-81025 intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100 psi-mi:dlgp2_rat(display_long)|uniprotkb:Dlgap2(gene name)|psi-mi:Dlgap2(display_short)|uniprotkb:Dap2(gene name synonym)|uniprotkb:SAP90/PSD-95-associated protein 2(gene name synonym)|uniprotkb:PSD-95/SAP90-binding protein 2(gene name synonym) psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yao et al. (1999) pubmed:10488079 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-80924 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620224|interpro:IPR005026(Guanylate-kinase-associated protein)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005883"(neurofilament)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0099572"(postsynaptic specialization)|reactome:R-RNO-6794361|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR030525|refseq:NP_446353.2|mint:P97837 rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1 pubmed:10488079(primary-reference) - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2003/12/16 2014/10/16 rogid:WFFaNSwGhTQ4B4JQBRSuHFFEKh010116 rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116 intact-crc:19AFFFE298B6BB08|rigid:TrGpFkJXEpdHdo+mcBov8G5nXpQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P97837 uniprotkb:P97836 intact:EBI-81025 intact:EBI-80901|uniprotkb:O54773|uniprotkb:P97841 psi-mi:dlgp2_rat(display_long)|uniprotkb:Dlgap2(gene name)|psi-mi:Dlgap2(display_short)|uniprotkb:Dap2(gene name synonym)|uniprotkb:SAP90/PSD-95-associated protein 2(gene name synonym)|uniprotkb:PSD-95/SAP90-binding protein 2(gene name synonym) psi-mi:dlgp1_rat(display_long)|uniprotkb:Dlgap1(gene name)|psi-mi:Dlgap1(display_short)|uniprotkb:Gkap(gene name synonym)|uniprotkb:Guanylate kinase-associated protein(gene name synonym)|uniprotkb:SAP90/PSD-95-associated protein 1(gene name synonym)|uniprotkb:PSD-95/SAP90-binding protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yao et al. (1999) pubmed:10488079 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-81039 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620224|interpro:IPR005026(Guanylate-kinase-associated protein)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005883"(neurofilament)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0099572"(postsynaptic specialization)|reactome:R-RNO-6794361|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR030525|refseq:NP_446353.2|mint:P97837 go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070842"(aggresome assembly)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0099572"(postsynaptic specialization)|rcsb pdb:4R0Y|rcsb pdb:5OVC|reactome:R-RNO-6794361|refseq:NP_001291216.1|rgd:620223|interpro:IPR005026(Guanylate-kinase-associated protein)|interpro:IPR030524|refseq:XP_008765652.1|refseq:XP_008765654.1|mint:P97836 pubmed:10488079(primary-reference) - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2003/12/16 2014/10/16 rogid:WFFaNSwGhTQ4B4JQBRSuHFFEKh010116 rogid:SkbS3bVadWCgL9ZlUsJ3V2tP2GM10116 intact-crc:C741C13C9516C6A8|rigid:hJyIhEBhg/YDY7CWjA76f6uq5eo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P97836 uniprotkb:Q9WV48 intact:EBI-80901|uniprotkb:O54773|uniprotkb:P97841 intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100 psi-mi:dlgp1_rat(display_long)|uniprotkb:Dlgap1(gene name)|psi-mi:Dlgap1(display_short)|uniprotkb:Gkap(gene name synonym)|uniprotkb:Guanylate kinase-associated protein(gene name synonym)|uniprotkb:SAP90/PSD-95-associated protein 1(gene name synonym)|uniprotkb:PSD-95/SAP90-binding protein 1(gene name synonym) psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Yao et al. (1999) pubmed:10488079 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-81011 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070842"(aggresome assembly)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0099572"(postsynaptic specialization)|rcsb pdb:4R0Y|rcsb pdb:5OVC|reactome:R-RNO-6794361|refseq:NP_001291216.1|rgd:620223|interpro:IPR005026(Guanylate-kinase-associated protein)|interpro:IPR030524|refseq:XP_008765652.1|refseq:XP_008765654.1|mint:P97836 rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1 pubmed:10488079(primary-reference) - - comment:"Cell type: rat crude synaptosomes." taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2003/12/16 2014/10/16 rogid:SkbS3bVadWCgL9ZlUsJ3V2tP2GM10116 rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116 intact-crc:8A2549DC90E61E17|rigid:O/cLT6ewRv0Cfbml8v+qi5WENmA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9WV48 uniprotkb:P97836 intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100 intact:EBI-80901|uniprotkb:O54773|uniprotkb:P97841 psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym) psi-mi:dlgp1_rat(display_long)|uniprotkb:Dlgap1(gene name)|psi-mi:Dlgap1(display_short)|uniprotkb:Gkap(gene name synonym)|uniprotkb:Guanylate kinase-associated protein(gene name synonym)|uniprotkb:SAP90/PSD-95-associated protein 1(gene name synonym)|uniprotkb:PSD-95/SAP90-binding protein 1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Yao et al. (1999) pubmed:10488079 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-81084 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1 go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070842"(aggresome assembly)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0099572"(postsynaptic specialization)|rcsb pdb:4R0Y|rcsb pdb:5OVC|reactome:R-RNO-6794361|refseq:NP_001291216.1|rgd:620223|interpro:IPR005026(Guanylate-kinase-associated protein)|interpro:IPR030524|refseq:XP_008765652.1|refseq:XP_008765654.1|mint:P97836 pubmed:10488079(primary-reference) - - comment:SAPAP1/PSD95 was Myc-tagged and tranfected into COS cells. The authors do not state which COS cell line. Shank1 was GST-tagged. taxid:-1(in vitro)|taxid:-1(In vitro) - 2003/12/16 2014/10/16 rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116 rogid:SkbS3bVadWCgL9ZlUsJ3V2tP2GM10116 intact-crc:670ACBB24954E547|rigid:O/cLT6ewRv0Cfbml8v+qi5WENmA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9WV48 uniprotkb:P19490 intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100 intact:EBI-371642 psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym) psi-mi:gria1_rat(display_long)|uniprotkb:Gria1(gene name)|psi-mi:Gria1(display_short)|uniprotkb:GluR-A(gene name synonym)|uniprotkb:GluR-K1(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 1(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 1(gene name synonym)|uniprotkb:Glur1(gene name synonym) psi-mi:"MI:0428"(imaging technique) Yao et al. (1999) pubmed:10488079 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-371659 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1 rgd:621531|refseq:NP_113796.1|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044297"(cell body)|go:"GO:0044308"(axonal spine)|go:"GO:0044309"(neuron spine)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060992"(response to fungicide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071418"(cellular response to amine stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009986"(cell surface)|go:"GO:0010226"(response to lithium ion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099544"(perisynaptic space)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2AWW|rcsb pdb:2G2L|rcsb pdb:3SAJ|go:"GO:0097060"(synaptic membrane)|rcsb pdb:6NJL|rcsb pdb:6NJN|rcsb pdb:6QKC|rcsb pdb:6QKZ|rcsb pdb:7OCA|rcsb pdb:7OCC|rcsb pdb:7OCD|rcsb pdb:7OCE|rcsb pdb:7OCF|reactome:R-RNO-204005|reactome:R-RNO-399710|reactome:R-RNO-399719|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007616"(long-term memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|reactome:R-RNO-438066|reactome:R-RNO-5694530|reactome:R-RNO-8849932|reactome:R-RNO-416993|mint:P19490|dip:DIP-30929N - - - - taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons) - 2003/12/16 2014/10/16 rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116 rogid:Bdkl7msqLXWZxd8172jZFghg6BI10116 intact-crc:B1BB49F70DD65405|rigid:zLdB/jIKMNlXvuxFLdQi/1AHK3k false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P19490 uniprotkb:P97836 intact:EBI-371642 intact:EBI-80901|uniprotkb:O54773|uniprotkb:P97841 psi-mi:gria1_rat(display_long)|uniprotkb:Gria1(gene name)|psi-mi:Gria1(display_short)|uniprotkb:GluR-A(gene name synonym)|uniprotkb:GluR-K1(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 1(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 1(gene name synonym)|uniprotkb:Glur1(gene name synonym) psi-mi:dlgp1_rat(display_long)|uniprotkb:Dlgap1(gene name)|psi-mi:Dlgap1(display_short)|uniprotkb:Gkap(gene name synonym)|uniprotkb:Guanylate kinase-associated protein(gene name synonym)|uniprotkb:SAP90/PSD-95-associated protein 1(gene name synonym)|uniprotkb:PSD-95/SAP90-binding protein 1(gene name synonym) psi-mi:"MI:0428"(imaging technique) Yao et al. (1999) pubmed:10488079 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-371662 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621531|refseq:NP_113796.1|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044297"(cell body)|go:"GO:0044308"(axonal spine)|go:"GO:0044309"(neuron spine)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060992"(response to fungicide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071418"(cellular response to amine stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009986"(cell surface)|go:"GO:0010226"(response to lithium ion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099544"(perisynaptic space)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2AWW|rcsb pdb:2G2L|rcsb pdb:3SAJ|go:"GO:0097060"(synaptic membrane)|rcsb pdb:6NJL|rcsb pdb:6NJN|rcsb pdb:6QKC|rcsb pdb:6QKZ|rcsb pdb:7OCA|rcsb pdb:7OCC|rcsb pdb:7OCD|rcsb pdb:7OCE|rcsb pdb:7OCF|reactome:R-RNO-204005|reactome:R-RNO-399710|reactome:R-RNO-399719|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007616"(long-term memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|reactome:R-RNO-438066|reactome:R-RNO-5694530|reactome:R-RNO-8849932|reactome:R-RNO-416993|mint:P19490|dip:DIP-30929N go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070842"(aggresome assembly)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0099572"(postsynaptic specialization)|rcsb pdb:4R0Y|rcsb pdb:5OVC|reactome:R-RNO-6794361|refseq:NP_001291216.1|rgd:620223|interpro:IPR005026(Guanylate-kinase-associated protein)|interpro:IPR030524|refseq:XP_008765652.1|refseq:XP_008765654.1|mint:P97836 - - - - taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons) - 2003/12/16 2014/10/16 rogid:Bdkl7msqLXWZxd8172jZFghg6BI10116 rogid:SkbS3bVadWCgL9ZlUsJ3V2tP2GM10116 intact-crc:0325F80797A51FB0|rigid:UlyRgMfF7RdiK2bjqoJEoSWaxk0 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)