#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P39935 uniprotkb:P10081 intact:EBI-9002|ensemblfungi:YGR162W|uniprotkb:D6VUU6 intact:EBI-9017|ensemblfungi:YKR059W|ensemblfungi:YJL138C|uniprotkb:D6VW46 psi-mi:if4f1_yeast(display_long)|uniprotkb:YGR162W(locus name)|uniprotkb:TIF4631(gene name)|psi-mi:TIF4631(display_short)|uniprotkb:eIF4G1(gene name synonym)|uniprotkb:mRNA cap-binding protein complex subunit p150(gene name synonym) psi-mi:if4a_yeast(display_long)|uniprotkb:Stimulator factor I 37 kDa component(gene name synonym)|uniprotkb:TIF41A(gene name synonym)|uniprotkb:TIF41B(gene name synonym)|uniprotkb:Translation initiation factor 1/2(gene name synonym)|uniprotkb:J0660(orf name)|uniprotkb:YJL138C(locus name)|uniprotkb:YKR059W(locus name)|uniprotkb:TIF1(gene name)|psi-mi:TIF1(display_short)|uniprotkb:TIF2(gene name)|psi-mi:TIF2(display_short)|uniprotkb:Eukaryotic initiation factor 4A(gene name synonym)|uniprotkb:p37(gene name synonym) psi-mi:"MI:0096"(pull down) Dominguez et al. (1999) pubmed:10480875 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-74685 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR162W(gene)|ensemblfungi:YGR162W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0034063"(stress granule assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|go:"GO:1902280"(regulation of RNA helicase activity)|rcsb pdb:2VSO|rcsb pdb:2VSX|rcsb pdb:6Z29|reactome:R-SCE-156827|reactome:R-SCE-166208|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|reactome:R-SCE-975956|reactome:R-SCE-975957|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022745|interpro:IPR036211|rcsb pdb:1RF8|refseq:NP_011678.3|sgd:S000003394|mint:P39935|dip:DIP-985N ensemblfungi:YJL138C(gene)|rcsb pdb:1QVA|rcsb pdb:2VSO|rcsb pdb:2VSX|reactome:R-SCE-156827|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|rcsb pdb:1QDE|ensemblfungi:YJL138C_mRNA(transcript)|ensemblfungi:YKR059W(gene)|ensemblfungi:YKR059W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|rcsb pdb:1FUK|rcsb pdb:1FUU|refseq:NP_012985.3|refseq:NP_012397.1|sgd:S000001767|sgd:S000003674|mint:P10081|dip:DIP-4571N pubmed:10480875(primary-reference) crc64:391256802F86118E crc64:19D8C133C815DD48 - taxid:-1(in vitro)|taxid:-1(In vitro) - 2003/11/06 2014/10/16 rogid:l5wtszbSL7dltfdiDAVe5zYnxVc559292 rogid:iEUvSBQzw5e9h9NnL8dTJCfbUqQ559292 intact-crc:56BCD8F372F95E7C|rigid:ylm1y7JAdfjnS6ewyN9x4BXYgsE false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P39935 uniprotkb:P10081 intact:EBI-9002|ensemblfungi:YGR162W|uniprotkb:D6VUU6 intact:EBI-9017|ensemblfungi:YKR059W|ensemblfungi:YJL138C|uniprotkb:D6VW46 psi-mi:if4f1_yeast(display_long)|uniprotkb:YGR162W(locus name)|uniprotkb:TIF4631(gene name)|psi-mi:TIF4631(display_short)|uniprotkb:eIF4G1(gene name synonym)|uniprotkb:mRNA cap-binding protein complex subunit p150(gene name synonym) psi-mi:if4a_yeast(display_long)|uniprotkb:Stimulator factor I 37 kDa component(gene name synonym)|uniprotkb:TIF41A(gene name synonym)|uniprotkb:TIF41B(gene name synonym)|uniprotkb:Translation initiation factor 1/2(gene name synonym)|uniprotkb:J0660(orf name)|uniprotkb:YJL138C(locus name)|uniprotkb:YKR059W(locus name)|uniprotkb:TIF1(gene name)|psi-mi:TIF1(display_short)|uniprotkb:TIF2(gene name)|psi-mi:TIF2(display_short)|uniprotkb:Eukaryotic initiation factor 4A(gene name synonym)|uniprotkb:p37(gene name synonym) psi-mi:"MI:0096"(pull down) Dominguez et al. (1999) pubmed:10480875 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-74689 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR162W(gene)|ensemblfungi:YGR162W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0034063"(stress granule assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|go:"GO:1902280"(regulation of RNA helicase activity)|rcsb pdb:2VSO|rcsb pdb:2VSX|rcsb pdb:6Z29|reactome:R-SCE-156827|reactome:R-SCE-166208|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|reactome:R-SCE-975956|reactome:R-SCE-975957|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022745|interpro:IPR036211|rcsb pdb:1RF8|refseq:NP_011678.3|sgd:S000003394|mint:P39935|dip:DIP-985N ensemblfungi:YJL138C(gene)|rcsb pdb:1QVA|rcsb pdb:2VSO|rcsb pdb:2VSX|reactome:R-SCE-156827|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|rcsb pdb:1QDE|ensemblfungi:YJL138C_mRNA(transcript)|ensemblfungi:YKR059W(gene)|ensemblfungi:YKR059W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|rcsb pdb:1FUK|rcsb pdb:1FUU|refseq:NP_012985.3|refseq:NP_012397.1|sgd:S000001767|sgd:S000003674|mint:P10081|dip:DIP-4571N - crc64:391256802F86118E crc64:19D8C133C815DD48 - taxid:-1(in vitro)|taxid:-1(In vitro) - 2003/11/06 2014/10/16 rogid:l5wtszbSL7dltfdiDAVe5zYnxVc559292 rogid:iEUvSBQzw5e9h9NnL8dTJCfbUqQ559292 intact-crc:B1F85A3F7D8BCEBD|rigid:ylm1y7JAdfjnS6ewyN9x4BXYgsE false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P39935 uniprotkb:P10081 intact:EBI-9002|ensemblfungi:YGR162W|uniprotkb:D6VUU6 intact:EBI-9017|ensemblfungi:YKR059W|ensemblfungi:YJL138C|uniprotkb:D6VW46 psi-mi:if4f1_yeast(display_long)|uniprotkb:YGR162W(locus name)|uniprotkb:TIF4631(gene name)|psi-mi:TIF4631(display_short)|uniprotkb:eIF4G1(gene name synonym)|uniprotkb:mRNA cap-binding protein complex subunit p150(gene name synonym) psi-mi:if4a_yeast(display_long)|uniprotkb:Stimulator factor I 37 kDa component(gene name synonym)|uniprotkb:TIF41A(gene name synonym)|uniprotkb:TIF41B(gene name synonym)|uniprotkb:Translation initiation factor 1/2(gene name synonym)|uniprotkb:J0660(orf name)|uniprotkb:YJL138C(locus name)|uniprotkb:YKR059W(locus name)|uniprotkb:TIF1(gene name)|psi-mi:TIF1(display_short)|uniprotkb:TIF2(gene name)|psi-mi:TIF2(display_short)|uniprotkb:Eukaryotic initiation factor 4A(gene name synonym)|uniprotkb:p37(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Dominguez et al. (1999) pubmed:10480875 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-74699 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR162W(gene)|ensemblfungi:YGR162W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0034063"(stress granule assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|go:"GO:1902280"(regulation of RNA helicase activity)|rcsb pdb:2VSO|rcsb pdb:2VSX|rcsb pdb:6Z29|reactome:R-SCE-156827|reactome:R-SCE-166208|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|reactome:R-SCE-975956|reactome:R-SCE-975957|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022745|interpro:IPR036211|rcsb pdb:1RF8|refseq:NP_011678.3|sgd:S000003394|mint:P39935|dip:DIP-985N ensemblfungi:YJL138C(gene)|rcsb pdb:1QVA|rcsb pdb:2VSO|rcsb pdb:2VSX|reactome:R-SCE-156827|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|rcsb pdb:1QDE|ensemblfungi:YJL138C_mRNA(transcript)|ensemblfungi:YKR059W(gene)|ensemblfungi:YKR059W_mRNA(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|rcsb pdb:1FUK|rcsb pdb:1FUU|refseq:NP_012985.3|refseq:NP_012397.1|sgd:S000001767|sgd:S000003674|mint:P10081|dip:DIP-4571N pubmed:10480875(primary-reference) crc64:391256802F86118E crc64:19D8C133C815DD48 - taxid:-1(in vitro)|taxid:-1(In vitro) - 2003/11/06 2014/10/16 rogid:l5wtszbSL7dltfdiDAVe5zYnxVc559292 rogid:iEUvSBQzw5e9h9NnL8dTJCfbUqQ559292 intact-crc:DD93AB859BC2732D|rigid:ylm1y7JAdfjnS6ewyN9x4BXYgsE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)