#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P51587	uniprotkb:P60896	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	intact:EBI-79819|ensembl:ENSP00000248566|uniprotkb:Q13437|uniprotkb:Q61067	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:sem1_human(display_long)|uniprotkb:C7orf76(gene name synonym)|uniprotkb:SEM1(gene name)|psi-mi:SEM1(display_short)|uniprotkb:26S proteasome complex subunit DSS1(gene name synonym)|uniprotkb:DSS1(gene name synonym)|uniprotkb:Deleted in split hand/split foot protein 1(gene name synonym)|uniprotkb:SHFDG1(gene name synonym)|uniprotkb:SHFM1(gene name synonym)|uniprotkb:Split hand/foot deleted protein 1(gene name synonym)|uniprotkb:Split hand/foot malformation type 1 protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Marston et al. (1999)	pubmed:10373512	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-79835	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	ensembl:ENSG00000127922(gene)|ensembl:ENST00000248566(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|interpro:IPR007834(DSS1/SEM1)|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:1IYJ|rcsb pdb:1MIU|rcsb pdb:1MJE|rcsb pdb:3T5X|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:5M32|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|rcsb pdb:5T0C|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:5T0G|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|rcsb pdb:5T0H|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VGZ|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_006295.1|dip:DIP-31023N	-	-	-	comment:BRCA2 C terminal fragment encoding AA 2472-2957 were impotant in pulling down SHDFG1 from HeLa and mammary tissue cDNA library.|dataset:Cancer - Interactions investigated in the context of cancer	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2003/12/09	2015/12/03	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	rogid:PWXTveLxuio5va1OslxM8lWAEK49606	intact-crc:BDB6A727EC11B596|rigid:0j6yw17EItt18+FG/WjclN+t1b4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51587	uniprotkb:P60896	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	intact:EBI-79819|ensembl:ENSP00000248566|uniprotkb:Q13437|uniprotkb:Q61067	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:sem1_human(display_long)|uniprotkb:C7orf76(gene name synonym)|uniprotkb:SEM1(gene name)|psi-mi:SEM1(display_short)|uniprotkb:26S proteasome complex subunit DSS1(gene name synonym)|uniprotkb:DSS1(gene name synonym)|uniprotkb:Deleted in split hand/split foot protein 1(gene name synonym)|uniprotkb:SHFDG1(gene name synonym)|uniprotkb:SHFM1(gene name synonym)|uniprotkb:Split hand/foot deleted protein 1(gene name synonym)|uniprotkb:Split hand/foot malformation type 1 protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Marston et al. (1999)	pubmed:10373512	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-79842	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	ensembl:ENSG00000127922(gene)|ensembl:ENST00000248566(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|interpro:IPR007834(DSS1/SEM1)|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:1IYJ|rcsb pdb:1MIU|rcsb pdb:1MJE|rcsb pdb:3T5X|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:5M32|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|rcsb pdb:5T0C|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:5T0G|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|rcsb pdb:5T0H|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VGZ|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_006295.1|dip:DIP-31023N	-	-	-	dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2003/12/09	2015/12/03	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	rogid:PWXTveLxuio5va1OslxM8lWAEK49606	intact-crc:FC9A1957CB894AB1|rigid:0j6yw17EItt18+FG/WjclN+t1b4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51587	uniprotkb:P60896	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	intact:EBI-79819|ensembl:ENSP00000248566|uniprotkb:Q13437|uniprotkb:Q61067	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:sem1_human(display_long)|uniprotkb:C7orf76(gene name synonym)|uniprotkb:SEM1(gene name)|psi-mi:SEM1(display_short)|uniprotkb:26S proteasome complex subunit DSS1(gene name synonym)|uniprotkb:DSS1(gene name synonym)|uniprotkb:Deleted in split hand/split foot protein 1(gene name synonym)|uniprotkb:SHFDG1(gene name synonym)|uniprotkb:SHFM1(gene name synonym)|uniprotkb:Split hand/foot deleted protein 1(gene name synonym)|uniprotkb:Split hand/foot malformation type 1 protein(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Marston et al. (1999)	pubmed:10373512	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-79847	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	ensembl:ENSG00000127922(gene)|ensembl:ENST00000248566(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|interpro:IPR007834(DSS1/SEM1)|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:1IYJ|rcsb pdb:1MIU|rcsb pdb:1MJE|rcsb pdb:3T5X|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:5M32|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|rcsb pdb:5T0C|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:5T0G|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|rcsb pdb:5T0H|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VGZ|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_006295.1|dip:DIP-31023N	-	-	-	dataset:Cancer - Interactions investigated in the context of cancer	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2003/12/09	2015/12/03	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	rogid:PWXTveLxuio5va1OslxM8lWAEK49606	intact-crc:669131FE7B18BDBF|rigid:0j6yw17EItt18+FG/WjclN+t1b4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P60896	uniprotkb:P51587	intact:EBI-79819|ensembl:ENSP00000248566|uniprotkb:Q13437|uniprotkb:Q61067	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	psi-mi:sem1_human(display_long)|uniprotkb:C7orf76(gene name synonym)|uniprotkb:SEM1(gene name)|psi-mi:SEM1(display_short)|uniprotkb:26S proteasome complex subunit DSS1(gene name synonym)|uniprotkb:DSS1(gene name synonym)|uniprotkb:Deleted in split hand/split foot protein 1(gene name synonym)|uniprotkb:SHFDG1(gene name synonym)|uniprotkb:SHFM1(gene name synonym)|uniprotkb:Split hand/foot deleted protein 1(gene name synonym)|uniprotkb:Split hand/foot malformation type 1 protein(gene name synonym)	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Marston et al. (1999)	pubmed:10373512	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-79852	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000127922(gene)|ensembl:ENST00000248566(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|interpro:IPR007834(DSS1/SEM1)|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:1IYJ|rcsb pdb:1MIU|rcsb pdb:1MJE|rcsb pdb:3T5X|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:5M32|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|rcsb pdb:5T0C|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:5T0G|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|rcsb pdb:5T0H|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VGZ|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_006295.1|dip:DIP-31023N	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	-	-	-	dataset:Cancer - Interactions investigated in the context of cancer	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2003/12/09	2015/12/03	rogid:PWXTveLxuio5va1OslxM8lWAEK49606	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	intact-crc:D75CABBF1D51965E|rigid:0j6yw17EItt18+FG/WjclN+t1b4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)