#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P28069	uniprotkb:P14921	intact:EBI-8673859|ensembl:ENSP00000263781|uniprotkb:Q9UEL3|uniprotkb:Q15133|intact:MINT-1521664|uniprotkb:Q9UD34|uniprotkb:O75757|uniprotkb:Q15132	intact:EBI-913209|uniprotkb:Q14278|uniprotkb:Q16080|ensembl:ENSP00000324578|uniprotkb:Q6N087|uniprotkb:A9UL17|uniprotkb:F5GYX9|uniprotkb:Q96AC5	psi-mi:pit1_human(display_long)|uniprotkb:POU1F1(gene name)|psi-mi:POU1F1(display_short)|uniprotkb:GHF1(gene name synonym)|uniprotkb:PIT1(gene name synonym)|uniprotkb:Growth hormone factor 1(gene name synonym)	psi-mi:ets1_human(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bradford et al. (1997)	mint:MINT-5221325|pubmed:9032233	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8673906|mint:MINT-14055	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013847(POU)|interpro:IPR015586(Pituitary-specific positive transcription factor 1)|interpro:IPR017970|rcsb pdb:5WC9|ensembl:ENSG00000064835(gene)|ensembl:ENST00000350375(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|refseq:NP_000297.1|refseq:NP_001116229.1|mint:MINT-1521707(identity)	go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0032355"(response to estradiol)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044849"(estrous cycle)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|mint:P14921|rcsb pdb:1GVJ|rcsb pdb:2NNY|rcsb pdb:2STT|rcsb pdb:2STW|rcsb pdb:3MFK|rcsb pdb:3RI4|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WTZ|rcsb pdb:3WU0|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|rcsb pdb:4LG0|rcsb pdb:5ZMC|reactome:R-HSA-2559585|refseq:NP_005229.1|ensembl:ENSG00000134954(gene)|ensembl:ENST00000319397(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|refseq:NP_001137292.1|refseq:NP_001155894.1|refseq:NP_001317380.1|refseq:XP_016872803.1|dip:DIP-35183N|mint:MINT-1521710(identity)	-	comment:mint|function:Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'|function:"Defects in POU1F1 are a cause of familial combined pituitary hormone deficiency (CPHD) [MIM:173110]. CPHD is characterized by impaired production of growth hormone (GH) and one or more of the other five anterior pituitary hormones"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2002/08/27	2014/10/16	rogid:vcnjMKSvDmyYc//qmDbH38+Feio9606	rogid:KP3E8/vvVBip6KrkyUpm9poWd/E9606	intact-crc:D8A5515983FC149F|rigid:jHd5afD4WhhcD/7FfJljVZTfzr4	false	-	binding-associated region:218-312(MINT-1521711)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)