#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P54731	uniprotkb:P25446	intact:EBI-8663987|ensembl:ENSMUSP00000099785|intact:MINT-1513304|uniprotkb:Q6P1F8	intact:EBI-296206|uniprotkb:Q9DCQ1|uniprotkb:Q6GT31|ensembl:ENSMUSP00000025691	psi-mi:faf1_mouse(display_long)|uniprotkb:Faf1(gene name)|psi-mi:Faf1(display_short)	psi-mi:tnr6_mouse(display_long)|uniprotkb:Fas(gene name)|psi-mi:Fas(display_short)|uniprotkb:Apt1(gene name synonym)|uniprotkb:Tnfrsf6(gene name synonym)|uniprotkb:FASLG receptor(gene name synonym)|uniprotkb:Apoptosis-mediating surface antigen FAS(gene name synonym)|uniprotkb:Apo-1 antigen(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chu et al. (1995)	mint:MINT-5220866|pubmed:8524870|doi:10.1073/pnas.92.25.11894	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8664013|mint:MINT-19032	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000010517(gene)|ensembl:ENSMUST00000102724(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008219"(cell death)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR029071|interpro:IPR033043|interpro:IPR036249|interpro:IPR044541|refseq:NP_032009.2|mint:MINT-1513327(identity)	go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|ensembl:ENSMUSG00000024778(gene)|ensembl:ENSMUST00000025691(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045121"(membrane raft)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:0036337"(Fas signaling pathway)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0005516"(calmodulin binding)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019900"(kinase binding)|go:"GO:0030141"(secretory granule)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034198"(cellular response to amino acid starvation)|refseq:NP_032013.2|go:"GO:0048536"(spleen development)|go:"GO:0050869"(negative regulation of B cell activation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070227"(lymphocyte apoptotic process)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097049"(motor neuron apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097440"(apical dendrite)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR008063(Fas receptor)|interpro:IPR011029(DEATH-like)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR033998|interpro:IPR033999|mint:P25446|rcsb pdb:2NA6|rcsb pdb:3OQ9|reactome:R-MMU-3371378|reactome:R-MMU-5218900|reactome:R-MMU-69416|reactome:R-MMU-75157|dip:DIP-31093N|mint:MINT-1513333(identity)	-	comment:mint|function:Potentiates but cannot initiate FAS-induced apoptosis|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2002/09/04	2014/10/16	rogid:wqnTbKeoS+2ORpxUY5LImiuC5W010090	rogid:ihK7Oxh+f0U7iYAsR2TlwLX3Ep410090	intact-crc:4BDF077D90921695|rigid:QJS8i6oex5Ytj8Wyvo0JSiLRhKg	false	tag:?-?(MINT-1513328)	binding-associated region:187-327(MINT-1513334)|tag:?-?(MINT-1513337)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54731	uniprotkb:P25446	intact:EBI-8663987|ensembl:ENSMUSP00000099785|intact:MINT-1513304|uniprotkb:Q6P1F8	intact:EBI-296206|uniprotkb:Q9DCQ1|uniprotkb:Q6GT31|ensembl:ENSMUSP00000025691	psi-mi:faf1_mouse(display_long)|uniprotkb:Faf1(gene name)|psi-mi:Faf1(display_short)	psi-mi:tnr6_mouse(display_long)|uniprotkb:Fas(gene name)|psi-mi:Fas(display_short)|uniprotkb:Apt1(gene name synonym)|uniprotkb:Tnfrsf6(gene name synonym)|uniprotkb:FASLG receptor(gene name synonym)|uniprotkb:Apoptosis-mediating surface antigen FAS(gene name synonym)|uniprotkb:Apo-1 antigen(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Chu et al. (1995)	mint:MINT-5220866|pubmed:8524870|doi:10.1073/pnas.92.25.11894	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8664041|mint:MINT-19031	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000010517(gene)|ensembl:ENSMUST00000102724(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008219"(cell death)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR029071|interpro:IPR033043|interpro:IPR036249|interpro:IPR044541|refseq:NP_032009.2|mint:MINT-1513347(identity)	go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|ensembl:ENSMUSG00000024778(gene)|ensembl:ENSMUST00000025691(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045121"(membrane raft)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:0036337"(Fas signaling pathway)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0005516"(calmodulin binding)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019900"(kinase binding)|go:"GO:0030141"(secretory granule)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034198"(cellular response to amino acid starvation)|refseq:NP_032013.2|go:"GO:0048536"(spleen development)|go:"GO:0050869"(negative regulation of B cell activation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070227"(lymphocyte apoptotic process)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097049"(motor neuron apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097440"(apical dendrite)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR008063(Fas receptor)|interpro:IPR011029(DEATH-like)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR033998|interpro:IPR033999|mint:P25446|rcsb pdb:2NA6|rcsb pdb:3OQ9|reactome:R-MMU-3371378|reactome:R-MMU-5218900|reactome:R-MMU-69416|reactome:R-MMU-75157|dip:DIP-31093N|mint:MINT-1513350(identity)	-	comment:mint|function:Potentiates but cannot initiate FAS-induced apoptosis|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2002/09/04	2014/10/16	rogid:wqnTbKeoS+2ORpxUY5LImiuC5W010090	rogid:ihK7Oxh+f0U7iYAsR2TlwLX3Ep410090	intact-crc:BCCF83B0BCC4B62A|rigid:QJS8i6oex5Ytj8Wyvo0JSiLRhKg	false	-	binding-associated region:187-327(MINT-1513351)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)