#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P55196	uniprotkb:P25791	intact:EBI-365875|uniprotkb:O75089|uniprotkb:Q5TIG6|uniprotkb:O75087|uniprotkb:O75088|uniprotkb:Q9NSN7|uniprotkb:Q9NU92|uniprotkb:Q5TIG7|uniprotkb:Q59FP0|ensembl:ENSP00000404595	intact:EBI-739696|uniprotkb:Q9HD58|ensembl:ENSP00000379175	psi-mi:afad_human(display_long)|uniprotkb:AFDN(gene name)|psi-mi:AFDN(display_short)|uniprotkb:AF6(gene name synonym)|uniprotkb:ALL1-fused gene from chromosome 6 protein(gene name synonym)|uniprotkb:Afadin adherens junction formation factor(gene name synonym)|uniprotkb:MLLT4(gene name synonym)	psi-mi:rbtn2_human(display_long)|uniprotkb:LMO2(gene name)|psi-mi:LMO2(display_short)|uniprotkb:RBTN2(gene name synonym)|uniprotkb:RHOM2(gene name synonym)|uniprotkb:TTG2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym)|uniprotkb:RBTNL1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bégay-Müller et al. (2002)	pubmed:12067721|mint:MINT-5215491	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8475737|mint:MINT-16706	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035089.1|refseq:NP_001193937.1|refseq:XP_005267053.1|ensembl:ENST00000392108|ensembl:ENSP00000375956|ensembl:ENST00000392112|ensembl:ENSP00000375960|ensembl:ENST00000400822|ensembl:ENSP00000383623|ensembl:ENSP00000404595|refseq:NP_001278893.1|ensembl:ENSG00000130396(gene)|ensembl:ENST00000447894(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0070160"(tight junction)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000159(Ras-association)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029071|interpro:IPR036034|interpro:IPR037977|mint:P55196|rcsb pdb:1T2M|rcsb pdb:1XZ9|rcsb pdb:2AIN|rcsb pdb:2EXG|rcsb pdb:5A6C|reactome:R-HSA-418990|go:"GO:0022409"(positive regulation of cell-cell adhesion)|mint:MINT-717050(identity)	refseq:NP_001135787.1|refseq:NP_001135788.1|refseq:NP_005565.2|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2XJY|rcsb pdb:2XJZ|rcsb pdb:2YPA|rcsb pdb:4KFZ|reactome:R-HSA-8939236|ensembl:ENSG00000135363(gene)|ensembl:ENST00000395833(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007275"(multicellular organism development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|refseq:XP_005252978.1|refseq:XP_016873216.1|refseq:XP_016873217.1|refseq:XP_016873218.1|refseq:XP_016873219.1|refseq:XP_016873220.1|refseq:XP_016873221.1|refseq:XP_016873222.1|mint:MINT-717055(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2002/08/29	2014/10/16	rogid:x7kK5K1+wAFZFdVopvQ/l496J5U9606	rogid:o3vD6A43ue8k3BhmFh/mgyYvhsw9606	intact-crc:EFF558897748324C|rigid:BizCCDjEOypHKuY6maQJDFSP1rM	false	binding-associated region:1123-1373(MINT-717051)	binding-associated region:26-158(MINT-717056)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P55196	uniprotkb:P25791	intact:EBI-365875|uniprotkb:O75089|uniprotkb:Q5TIG6|uniprotkb:O75087|uniprotkb:O75088|uniprotkb:Q9NSN7|uniprotkb:Q9NU92|uniprotkb:Q5TIG7|uniprotkb:Q59FP0|ensembl:ENSP00000404595	intact:EBI-739696|uniprotkb:Q9HD58|ensembl:ENSP00000379175	psi-mi:afad_human(display_long)|uniprotkb:AFDN(gene name)|psi-mi:AFDN(display_short)|uniprotkb:AF6(gene name synonym)|uniprotkb:ALL1-fused gene from chromosome 6 protein(gene name synonym)|uniprotkb:Afadin adherens junction formation factor(gene name synonym)|uniprotkb:MLLT4(gene name synonym)	psi-mi:rbtn2_human(display_long)|uniprotkb:LMO2(gene name)|psi-mi:LMO2(display_short)|uniprotkb:RBTN2(gene name synonym)|uniprotkb:RHOM2(gene name synonym)|uniprotkb:TTG2(gene name synonym)|uniprotkb:LIM domain only protein 2(gene name synonym)|uniprotkb:Cysteine-rich protein TTG-2(gene name synonym)|uniprotkb:T-cell translocation protein 2(gene name synonym)|uniprotkb:RBTNL1(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Bégay-Müller et al. (2002)	pubmed:12067721|mint:MINT-5215491	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8475802|mint:MINT-16707	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035089.1|refseq:NP_001193937.1|refseq:XP_005267053.1|ensembl:ENST00000392108|ensembl:ENSP00000375956|ensembl:ENST00000392112|ensembl:ENSP00000375960|ensembl:ENST00000400822|ensembl:ENSP00000383623|ensembl:ENSP00000404595|refseq:NP_001278893.1|ensembl:ENSG00000130396(gene)|ensembl:ENST00000447894(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0070160"(tight junction)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000159(Ras-association)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029071|interpro:IPR036034|interpro:IPR037977|mint:P55196|rcsb pdb:1T2M|rcsb pdb:1XZ9|rcsb pdb:2AIN|rcsb pdb:2EXG|rcsb pdb:5A6C|reactome:R-HSA-418990|go:"GO:0022409"(positive regulation of cell-cell adhesion)|mint:MINT-717065(identity)	refseq:NP_001135787.1|refseq:NP_001135788.1|refseq:NP_005565.2|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2XJY|rcsb pdb:2XJZ|rcsb pdb:2YPA|rcsb pdb:4KFZ|reactome:R-HSA-8939236|ensembl:ENSG00000135363(gene)|ensembl:ENST00000395833(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007275"(multicellular organism development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|refseq:XP_005252978.1|refseq:XP_016873216.1|refseq:XP_016873217.1|refseq:XP_016873218.1|refseq:XP_016873219.1|refseq:XP_016873220.1|refseq:XP_016873221.1|refseq:XP_016873222.1|mint:MINT-717070(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2002/08/29	2014/10/16	rogid:x7kK5K1+wAFZFdVopvQ/l496J5U9606	rogid:o3vD6A43ue8k3BhmFh/mgyYvhsw9606	intact-crc:6AB7E59A764E5821|rigid:BizCCDjEOypHKuY6maQJDFSP1rM	false	binding-associated region:1123-1373(MINT-717066)	binding-associated region:26-158(MINT-717071)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)