#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9Y2G2	uniprotkb:Q9Y2G2	intact:EBI-2808370|ensembl:ENSP00000375767|ensembl:ENSP00000428883|ensembl:ENSP00000499211|uniprotkb:Q96P82|uniprotkb:Q6PGP8|uniprotkb:B7Z496|uniprotkb:B7Z4A2|uniprotkb:G3XAM9|uniprotkb:B5KVR6|uniprotkb:E9PEM7|uniprotkb:B5KVR8|uniprotkb:E5RFV9	intact:EBI-2808370|ensembl:ENSP00000375767|ensembl:ENSP00000428883|ensembl:ENSP00000499211|uniprotkb:Q96P82|uniprotkb:Q6PGP8|uniprotkb:B7Z496|uniprotkb:B7Z4A2|uniprotkb:G3XAM9|uniprotkb:B5KVR6|uniprotkb:E9PEM7|uniprotkb:B5KVR8|uniprotkb:E5RFV9	psi-mi:card8_human(display_long)|uniprotkb:CARD8(gene name)|psi-mi:CARD8(display_short)|uniprotkb:KIAA0955(gene name synonym)|uniprotkb:NDPP1(gene name synonym)|uniprotkb:CARD-inhibitor of NF-kappa-B-activating ligand(gene name synonym)|uniprotkb:DACAR(gene name synonym)|uniprotkb:Tumor up-regulated CARD-containing antagonist of CASP9(gene name synonym)	psi-mi:card8_human(display_long)|uniprotkb:CARD8(gene name)|psi-mi:CARD8(display_short)|uniprotkb:KIAA0955(gene name synonym)|uniprotkb:NDPP1(gene name synonym)|uniprotkb:CARD-inhibitor of NF-kappa-B-activating ligand(gene name synonym)|uniprotkb:DACAR(gene name synonym)|uniprotkb:Tumor up-regulated CARD-containing antagonist of CASP9(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Stilo et al. (2002)	pubmed:12067710|mint:MINT-5215482	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8470267|mint:MINT-18290	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105483(gene)|ensembl:ENST00000391898(transcript)|ensembl:ENST00000519940(transcript)|ensembl:ENST00000651546(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008233"(peptidase activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032089"(NACHT domain binding)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043621"(protein self-association)|go:"GO:0050700"(CARD domain binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061702"(inflammasome complex)|go:"GO:0070269"(pyroptosis)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0097264"(self proteolysis)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140608"(cysteine-type endopeptidase activator activity)|go:"GO:0140633"(CARD8 inflammasome complex assembly)|go:"GO:0140634"(CARD8 inflammasome complex)|go:"GO:1900226"(negative regulation of NLRP3 inflammasome complex assembly)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR025307|rcsb pdb:4IKM|rcsb pdb:6K9F|rcsb pdb:6XKJ|rcsb pdb:7JKQ|rcsb pdb:7JN7|reactome:R-HSA-111458|reactome:R-HSA-9627069|refseq:XP_011524943.1|refseq:XP_011524944.1|refseq:XP_011524945.1|refseq:XP_011524946.1|refseq:XP_011524952.1|refseq:NP_001171833.1|refseq:XP_006723173.1|refseq:NP_001171829.1|refseq:NP_001171830.1|refseq:NP_001171831.1|refseq:NP_001171832.1|refseq:NP_055774.2|refseq:XP_016881972.1|refseq:XP_016881979.1|refseq:XP_016881987.1|refseq:XP_006723154.1|refseq:XP_006723155.1|refseq:XP_006723156.1|refseq:XP_006723158.1|refseq:XP_006723159.1|refseq:XP_006723160.1|refseq:XP_006723167.1|refseq:XP_006723169.1|refseq:XP_006723172.1|mint:MINT-716922(identity)	ensembl:ENSG00000105483(gene)|ensembl:ENST00000391898(transcript)|ensembl:ENST00000519940(transcript)|ensembl:ENST00000651546(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008233"(peptidase activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032089"(NACHT domain binding)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043621"(protein self-association)|go:"GO:0050700"(CARD domain binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061702"(inflammasome complex)|go:"GO:0070269"(pyroptosis)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0097264"(self proteolysis)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140608"(cysteine-type endopeptidase activator activity)|go:"GO:0140633"(CARD8 inflammasome complex assembly)|go:"GO:0140634"(CARD8 inflammasome complex)|go:"GO:1900226"(negative regulation of NLRP3 inflammasome complex assembly)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR025307|rcsb pdb:4IKM|rcsb pdb:6K9F|rcsb pdb:6XKJ|rcsb pdb:7JKQ|rcsb pdb:7JN7|reactome:R-HSA-111458|reactome:R-HSA-9627069|refseq:XP_011524943.1|refseq:XP_011524944.1|refseq:XP_011524945.1|refseq:XP_011524946.1|refseq:XP_011524952.1|refseq:NP_001171833.1|refseq:XP_006723173.1|refseq:NP_001171829.1|refseq:NP_001171830.1|refseq:NP_001171831.1|refseq:NP_001171832.1|refseq:NP_055774.2|refseq:XP_016881972.1|refseq:XP_016881979.1|refseq:XP_016881987.1|refseq:XP_006723154.1|refseq:XP_006723155.1|refseq:XP_006723156.1|refseq:XP_006723158.1|refseq:XP_006723159.1|refseq:XP_006723160.1|refseq:XP_006723167.1|refseq:XP_006723169.1|refseq:XP_006723172.1|mint:MINT-716916(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2002/09/24	2021/06/18	rogid:WCpalGD3/kZFOTQQNc42fKReKAA9606	rogid:WCpalGD3/kZFOTQQNc42fKReKAA9606	intact-crc:157D72D577534B98|rigid:mUkpw4Qf2zZjeeFks5YqpcTiHc4	false	-	binding-associated region:285-537(MINT-716917)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14192	uniprotkb:Q9Y2G2	intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15	intact:EBI-2808370|ensembl:ENSP00000375767|ensembl:ENSP00000428883|ensembl:ENSP00000499211|uniprotkb:Q96P82|uniprotkb:Q6PGP8|uniprotkb:B7Z496|uniprotkb:B7Z4A2|uniprotkb:G3XAM9|uniprotkb:B5KVR6|uniprotkb:E9PEM7|uniprotkb:B5KVR8|uniprotkb:E5RFV9	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	psi-mi:card8_human(display_long)|uniprotkb:CARD8(gene name)|psi-mi:CARD8(display_short)|uniprotkb:KIAA0955(gene name synonym)|uniprotkb:NDPP1(gene name synonym)|uniprotkb:CARD-inhibitor of NF-kappa-B-activating ligand(gene name synonym)|uniprotkb:DACAR(gene name synonym)|uniprotkb:Tumor up-regulated CARD-containing antagonist of CASP9(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Stilo et al. (2002)	pubmed:12067710|mint:MINT-5215482	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8470319|mint:MINT-18623	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|mint:MINT-716972(identity)	ensembl:ENSG00000105483(gene)|ensembl:ENST00000391898(transcript)|ensembl:ENST00000519940(transcript)|ensembl:ENST00000651546(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008233"(peptidase activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032089"(NACHT domain binding)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043621"(protein self-association)|go:"GO:0050700"(CARD domain binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061702"(inflammasome complex)|go:"GO:0070269"(pyroptosis)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0097264"(self proteolysis)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140608"(cysteine-type endopeptidase activator activity)|go:"GO:0140633"(CARD8 inflammasome complex assembly)|go:"GO:0140634"(CARD8 inflammasome complex)|go:"GO:1900226"(negative regulation of NLRP3 inflammasome complex assembly)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR025307|rcsb pdb:4IKM|rcsb pdb:6K9F|rcsb pdb:6XKJ|rcsb pdb:7JKQ|rcsb pdb:7JN7|reactome:R-HSA-111458|reactome:R-HSA-9627069|refseq:XP_011524943.1|refseq:XP_011524944.1|refseq:XP_011524945.1|refseq:XP_011524946.1|refseq:XP_011524952.1|refseq:NP_001171833.1|refseq:XP_006723173.1|refseq:NP_001171829.1|refseq:NP_001171830.1|refseq:NP_001171831.1|refseq:NP_001171832.1|refseq:NP_055774.2|refseq:XP_016881972.1|refseq:XP_016881979.1|refseq:XP_016881987.1|refseq:XP_006723154.1|refseq:XP_006723155.1|refseq:XP_006723156.1|refseq:XP_006723158.1|refseq:XP_006723159.1|refseq:XP_006723160.1|refseq:XP_006723167.1|refseq:XP_006723169.1|refseq:XP_006723172.1|mint:MINT-716966(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2002/09/24	2021/06/18	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	rogid:WCpalGD3/kZFOTQQNc42fKReKAA9606	intact-crc:AE7840D947015F23|rigid:Vpxv+SyDpE7qTq27BNFK+gUEpZw	false	-	binding-associated region:285-447(MINT-716967)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y2G2	uniprotkb:Q9Y2G2	intact:EBI-2808370|ensembl:ENSP00000375767|ensembl:ENSP00000428883|ensembl:ENSP00000499211|uniprotkb:Q96P82|uniprotkb:Q6PGP8|uniprotkb:B7Z496|uniprotkb:B7Z4A2|uniprotkb:G3XAM9|uniprotkb:B5KVR6|uniprotkb:E9PEM7|uniprotkb:B5KVR8|uniprotkb:E5RFV9	intact:EBI-2808370|ensembl:ENSP00000375767|ensembl:ENSP00000428883|ensembl:ENSP00000499211|uniprotkb:Q96P82|uniprotkb:Q6PGP8|uniprotkb:B7Z496|uniprotkb:B7Z4A2|uniprotkb:G3XAM9|uniprotkb:B5KVR6|uniprotkb:E9PEM7|uniprotkb:B5KVR8|uniprotkb:E5RFV9	psi-mi:card8_human(display_long)|uniprotkb:CARD8(gene name)|psi-mi:CARD8(display_short)|uniprotkb:KIAA0955(gene name synonym)|uniprotkb:NDPP1(gene name synonym)|uniprotkb:CARD-inhibitor of NF-kappa-B-activating ligand(gene name synonym)|uniprotkb:DACAR(gene name synonym)|uniprotkb:Tumor up-regulated CARD-containing antagonist of CASP9(gene name synonym)	psi-mi:card8_human(display_long)|uniprotkb:CARD8(gene name)|psi-mi:CARD8(display_short)|uniprotkb:KIAA0955(gene name synonym)|uniprotkb:NDPP1(gene name synonym)|uniprotkb:CARD-inhibitor of NF-kappa-B-activating ligand(gene name synonym)|uniprotkb:DACAR(gene name synonym)|uniprotkb:Tumor up-regulated CARD-containing antagonist of CASP9(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Stilo et al. (2002)	pubmed:12067710|mint:MINT-5215482	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8470342|mint:MINT-18289	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105483(gene)|ensembl:ENST00000391898(transcript)|ensembl:ENST00000519940(transcript)|ensembl:ENST00000651546(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008233"(peptidase activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032089"(NACHT domain binding)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043621"(protein self-association)|go:"GO:0050700"(CARD domain binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061702"(inflammasome complex)|go:"GO:0070269"(pyroptosis)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0097264"(self proteolysis)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140608"(cysteine-type endopeptidase activator activity)|go:"GO:0140633"(CARD8 inflammasome complex assembly)|go:"GO:0140634"(CARD8 inflammasome complex)|go:"GO:1900226"(negative regulation of NLRP3 inflammasome complex assembly)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR025307|rcsb pdb:4IKM|rcsb pdb:6K9F|rcsb pdb:6XKJ|rcsb pdb:7JKQ|rcsb pdb:7JN7|reactome:R-HSA-111458|reactome:R-HSA-9627069|refseq:XP_011524943.1|refseq:XP_011524944.1|refseq:XP_011524945.1|refseq:XP_011524946.1|refseq:XP_011524952.1|refseq:NP_001171833.1|refseq:XP_006723173.1|refseq:NP_001171829.1|refseq:NP_001171830.1|refseq:NP_001171831.1|refseq:NP_001171832.1|refseq:NP_055774.2|refseq:XP_016881972.1|refseq:XP_016881979.1|refseq:XP_016881987.1|refseq:XP_006723154.1|refseq:XP_006723155.1|refseq:XP_006723156.1|refseq:XP_006723158.1|refseq:XP_006723159.1|refseq:XP_006723160.1|refseq:XP_006723167.1|refseq:XP_006723169.1|refseq:XP_006723172.1|mint:MINT-716939(identity)	ensembl:ENSG00000105483(gene)|ensembl:ENST00000391898(transcript)|ensembl:ENST00000519940(transcript)|ensembl:ENST00000651546(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008233"(peptidase activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032089"(NACHT domain binding)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043621"(protein self-association)|go:"GO:0050700"(CARD domain binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061702"(inflammasome complex)|go:"GO:0070269"(pyroptosis)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0097264"(self proteolysis)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140608"(cysteine-type endopeptidase activator activity)|go:"GO:0140633"(CARD8 inflammasome complex assembly)|go:"GO:0140634"(CARD8 inflammasome complex)|go:"GO:1900226"(negative regulation of NLRP3 inflammasome complex assembly)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR025307|rcsb pdb:4IKM|rcsb pdb:6K9F|rcsb pdb:6XKJ|rcsb pdb:7JKQ|rcsb pdb:7JN7|reactome:R-HSA-111458|reactome:R-HSA-9627069|refseq:XP_011524943.1|refseq:XP_011524944.1|refseq:XP_011524945.1|refseq:XP_011524946.1|refseq:XP_011524952.1|refseq:NP_001171833.1|refseq:XP_006723173.1|refseq:NP_001171829.1|refseq:NP_001171830.1|refseq:NP_001171831.1|refseq:NP_001171832.1|refseq:NP_055774.2|refseq:XP_016881972.1|refseq:XP_016881979.1|refseq:XP_016881987.1|refseq:XP_006723154.1|refseq:XP_006723155.1|refseq:XP_006723156.1|refseq:XP_006723158.1|refseq:XP_006723159.1|refseq:XP_006723160.1|refseq:XP_006723167.1|refseq:XP_006723169.1|refseq:XP_006723172.1|mint:MINT-716930(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2002/09/24	2021/06/18	rogid:WCpalGD3/kZFOTQQNc42fKReKAA9606	rogid:WCpalGD3/kZFOTQQNc42fKReKAA9606	intact-crc:B16DF81A40C74A30|rigid:mUkpw4Qf2zZjeeFks5YqpcTiHc4	false	tag:?-?(MINT-716940)	binding-associated region:285-537(MINT-716931)|tag:?-?(MINT-716934)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2G2	uniprotkb:Q14192	intact:EBI-2808370|ensembl:ENSP00000375767|ensembl:ENSP00000428883|ensembl:ENSP00000499211|uniprotkb:Q96P82|uniprotkb:Q6PGP8|uniprotkb:B7Z496|uniprotkb:B7Z4A2|uniprotkb:G3XAM9|uniprotkb:B5KVR6|uniprotkb:E9PEM7|uniprotkb:B5KVR8|uniprotkb:E5RFV9	intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15	psi-mi:card8_human(display_long)|uniprotkb:CARD8(gene name)|psi-mi:CARD8(display_short)|uniprotkb:KIAA0955(gene name synonym)|uniprotkb:NDPP1(gene name synonym)|uniprotkb:CARD-inhibitor of NF-kappa-B-activating ligand(gene name synonym)|uniprotkb:DACAR(gene name synonym)|uniprotkb:Tumor up-regulated CARD-containing antagonist of CASP9(gene name synonym)	psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Stilo et al. (2002)	pubmed:12067710|mint:MINT-5215482	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8470412|mint:MINT-18622	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105483(gene)|ensembl:ENST00000391898(transcript)|ensembl:ENST00000519940(transcript)|ensembl:ENST00000651546(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008233"(peptidase activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032089"(NACHT domain binding)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043621"(protein self-association)|go:"GO:0050700"(CARD domain binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061702"(inflammasome complex)|go:"GO:0070269"(pyroptosis)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0097264"(self proteolysis)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140608"(cysteine-type endopeptidase activator activity)|go:"GO:0140633"(CARD8 inflammasome complex assembly)|go:"GO:0140634"(CARD8 inflammasome complex)|go:"GO:1900226"(negative regulation of NLRP3 inflammasome complex assembly)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR025307|rcsb pdb:4IKM|rcsb pdb:6K9F|rcsb pdb:6XKJ|rcsb pdb:7JKQ|rcsb pdb:7JN7|reactome:R-HSA-111458|reactome:R-HSA-9627069|refseq:XP_011524943.1|refseq:XP_011524944.1|refseq:XP_011524945.1|refseq:XP_011524946.1|refseq:XP_011524952.1|refseq:NP_001171833.1|refseq:XP_006723173.1|refseq:NP_001171829.1|refseq:NP_001171830.1|refseq:NP_001171831.1|refseq:NP_001171832.1|refseq:NP_055774.2|refseq:XP_016881972.1|refseq:XP_016881979.1|refseq:XP_016881987.1|refseq:XP_006723154.1|refseq:XP_006723155.1|refseq:XP_006723156.1|refseq:XP_006723158.1|refseq:XP_006723159.1|refseq:XP_006723160.1|refseq:XP_006723167.1|refseq:XP_006723169.1|refseq:XP_006723172.1|mint:MINT-716948(identity)	ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781|mint:MINT-716957(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2002/09/24	2021/06/18	rogid:WCpalGD3/kZFOTQQNc42fKReKAA9606	rogid:4X5kI037ASzuT1zACXH89BkwDBk9606	intact-crc:20DE313BE9C025CE|rigid:Vpxv+SyDpE7qTq27BNFK+gUEpZw	false	tag:?-?(MINT-716952)|binding-associated region:285-447(IPR001315)	tag:?-?(MINT-716958)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)