#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P16892 uniprotkb:P08539 intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W intact:EBI-7376|uniprotkb:D3DKU8|ensemblfungi:YHR005C psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name) psi-mi:gpa1_yeast(display_long)|uniprotkb:YHR005C(locus name)|uniprotkb:GPA1(gene name)|psi-mi:GPA1(display_short)|uniprotkb:CDC70(gene name synonym)|uniprotkb:DAC1(gene name synonym)|uniprotkb:SCG1(gene name synonym)|uniprotkb:GP1-alpha(gene name synonym) psi-mi:"MI:0096"(pull down) Metodiev et al. (2002) pubmed:12029138|mint:MINT-5215421 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8437552|mint:MINT-17645 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635|mint:MINT-715674(identity) refseq:NP_011868.1|sgd:S000001047|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-416482|dip:DIP-15N|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148|ensemblfungi:YHR005C(gene)|ensemblfungi:YHR005C_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071701"(regulation of MAPK export from nucleus)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:1SCG|rcsb pdb:7AD3|mint:MINT-715671(identity) - crc64:5117980D20A1E7E2|comment:"Stoichiometry: 1.0" crc64:2E87C546E133D6E5|comment:"Stoichiometry: 1.0" comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2002/06/24 2014/10/16 rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292 rogid:SxuqaRpicb7ZBsQju2vD6C8h3X4559292 intact-crc:FF9370FB166E7492|rigid:0x33VdQz2kMV9uFhWZQJ/LLW3do false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08539 uniprotkb:P16892 intact:EBI-7376|uniprotkb:D3DKU8|ensemblfungi:YHR005C intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W psi-mi:gpa1_yeast(display_long)|uniprotkb:YHR005C(locus name)|uniprotkb:GPA1(gene name)|psi-mi:GPA1(display_short)|uniprotkb:CDC70(gene name synonym)|uniprotkb:DAC1(gene name synonym)|uniprotkb:SCG1(gene name synonym)|uniprotkb:GP1-alpha(gene name synonym) psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name) psi-mi:"MI:0019"(coimmunoprecipitation) Metodiev et al. (2002) pubmed:12029138|mint:MINT-5215421 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8437586|mint:MINT-17646 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011868.1|sgd:S000001047|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-416482|dip:DIP-15N|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148|ensemblfungi:YHR005C(gene)|ensemblfungi:YHR005C_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071701"(regulation of MAPK export from nucleus)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:1SCG|rcsb pdb:7AD3|mint:MINT-715681(identity) refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635|mint:MINT-715684(identity) - crc64:2E87C546E133D6E5|comment:"Stoichiometry: 1.0" crc64:5117980D20A1E7E2|comment:"Stoichiometry: 1.0" comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2002/06/24 2014/10/16 rogid:SxuqaRpicb7ZBsQju2vD6C8h3X4559292 rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292 intact-crc:FAF624CA9801E92D|rigid:0x33VdQz2kMV9uFhWZQJ/LLW3do false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)